| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-126 |
Sentence |
denotes |
Plasma Ip(a) concentration is inversely correlated with the ratio of Kringle IV/Kringle V encoding domains in the apo(a) gene. |
| TextSentencer_T2 |
127-193 |
Sentence |
denotes |
Plasma Lp(a) levels correlate with atherosclerosis susceptibility. |
| TextSentencer_T3 |
194-291 |
Sentence |
denotes |
This lipoprotein consists of an LDL-like particle attached to a large glycoprotein called apo(a). |
| TextSentencer_T4 |
292-483 |
Sentence |
denotes |
Apo(a) is a complex glycoprotein containing multiple Kringle domains, found to be highly homologous to plasminogen Kringle IV, and a single Kringle domain homologous to plasminogen Kringle V. |
| TextSentencer_T5 |
484-570 |
Sentence |
denotes |
Lp(a) levels appear to be inversely correlated with apo(a) size in a given individual. |
| TextSentencer_T6 |
571-706 |
Sentence |
denotes |
In this study, we have used probes specific to the Kringles IV and V domains of apo(a) cDNA in quantitative Southern blotting analysis. |
| TextSentencer_T7 |
707-886 |
Sentence |
denotes |
By this method, we have determined the ratio of Kringle IV/Kringle V encoding domains in the apo(a) gene of 53 unrelated individuals with different plasma concentrations of Lp(a). |
| TextSentencer_T8 |
887-1087 |
Sentence |
denotes |
This ratio was found to be inversely correlated with log Lp(a) levels (r = -0.90, P less than 0.0001) and directly correlated with apo(a) apparent molecular weight (Mr) (r = 0.79, P less than 0.0001). |
| TextSentencer_T9 |
1088-1404 |
Sentence |
denotes |
In summary, by showing that Lp(a) concentrations and apo(a) apparent size are highly correlated with the ratio of Kringle IV/Kringle V encoding domains in the apo(a) gene, we provide a DNA marker for this atherosclerosis risk factor as well as an important insight into the genetic mechanism regulating Lp(a) levels. |
| T1 |
0-126 |
Sentence |
denotes |
Plasma Ip(a) concentration is inversely correlated with the ratio of Kringle IV/Kringle V encoding domains in the apo(a) gene. |
| T2 |
127-193 |
Sentence |
denotes |
Plasma Lp(a) levels correlate with atherosclerosis susceptibility. |
| T3 |
194-291 |
Sentence |
denotes |
This lipoprotein consists of an LDL-like particle attached to a large glycoprotein called apo(a). |
| T4 |
292-483 |
Sentence |
denotes |
Apo(a) is a complex glycoprotein containing multiple Kringle domains, found to be highly homologous to plasminogen Kringle IV, and a single Kringle domain homologous to plasminogen Kringle V. |
| T5 |
484-570 |
Sentence |
denotes |
Lp(a) levels appear to be inversely correlated with apo(a) size in a given individual. |
| T6 |
571-706 |
Sentence |
denotes |
In this study, we have used probes specific to the Kringles IV and V domains of apo(a) cDNA in quantitative Southern blotting analysis. |
| T7 |
707-886 |
Sentence |
denotes |
By this method, we have determined the ratio of Kringle IV/Kringle V encoding domains in the apo(a) gene of 53 unrelated individuals with different plasma concentrations of Lp(a). |
| T8 |
887-1087 |
Sentence |
denotes |
This ratio was found to be inversely correlated with log Lp(a) levels (r = -0.90, P less than 0.0001) and directly correlated with apo(a) apparent molecular weight (Mr) (r = 0.79, P less than 0.0001). |
| T9 |
1088-1404 |
Sentence |
denotes |
In summary, by showing that Lp(a) concentrations and apo(a) apparent size are highly correlated with the ratio of Kringle IV/Kringle V encoding domains in the apo(a) gene, we provide a DNA marker for this atherosclerosis risk factor as well as an important insight into the genetic mechanism regulating Lp(a) levels. |
