PubMed:25482837 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/25482837","sourcedb":"PubMed","sourceid":"25482837","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/25482837","text":"The Chinese First-Episode Schizophrenia Trial: background and study design.\nSchizophrenia is a complex illness with unknown aetiology and pathogenesis. Currently, a considerable number of patients with schizophrenia do not receive standardised and systematic treatment in China. In the past years, many controlled trials have been conducted in chronic schizophrenia. In contrast, research on first-episode schizophrenia is lacking. This paper describes the background and design of the Chinese First-Episode Schizophrenia Trial project--a multicentre, randomised, open-label clinical trial. A total of 600 first-episode schizophrenia patients were randomly divided into 3 groups and treated with risperidone, aripiprazole, and olanzapine for 1 year. During the study period, only 1 medication change of the 3 antipsychotic medications was allowed.","tracks":[{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":76,"end":89},"obj":"HP_0100753"},{"id":"T2","span":{"begin":202,"end":215},"obj":"HP_0100753"},{"id":"T3","span":{"begin":352,"end":365},"obj":"HP_0100753"},{"id":"T4","span":{"begin":406,"end":419},"obj":"HP_0100753"},{"id":"T5","span":{"begin":508,"end":521},"obj":"HP_0100753"},{"id":"T6","span":{"begin":620,"end":633},"obj":"HP_0100753"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"},{"subj":"T3","pred":"source","obj":"PubmedHPO"},{"subj":"T4","pred":"source","obj":"PubmedHPO"},{"subj":"T5","pred":"source","obj":"PubmedHPO"},{"subj":"T6","pred":"source","obj":"PubmedHPO"}]},{"project":"maxiaofeng52_800_3","denotations":[{"id":"T1","span":{"begin":508,"end":521},"obj":"DP"},{"id":"T2","span":{"begin":26,"end":39},"obj":"DP"},{"id":"T3","span":{"begin":76,"end":89},"obj":"DP"},{"id":"T4","span":{"begin":696,"end":707},"obj":"CI"},{"id":"T5","span":{"begin":709,"end":721},"obj":"CI"},{"id":"T6","span":{"begin":727,"end":737},"obj":"CI"},{"id":"T7","span":{"begin":202,"end":215},"obj":"DP"},{"id":"T8","span":{"begin":352,"end":365},"obj":"DP"},{"id":"T9","span":{"begin":406,"end":419},"obj":"DP"},{"id":"T10","span":{"begin":620,"end":633},"obj":"DP"}],"attributes":[{"subj":"T1","pred":"source","obj":"maxiaofeng52_800_3"},{"subj":"T2","pred":"source","obj":"maxiaofeng52_800_3"},{"subj":"T3","pred":"source","obj":"maxiaofeng52_800_3"},{"subj":"T4","pred":"source","obj":"maxiaofeng52_800_3"},{"subj":"T5","pred":"source","obj":"maxiaofeng52_800_3"},{"subj":"T6","pred":"source","obj":"maxiaofeng52_800_3"},{"subj":"T7","pred":"source","obj":"maxiaofeng52_800_3"},{"subj":"T8","pred":"source","obj":"maxiaofeng52_800_3"},{"subj":"T9","pred":"source","obj":"maxiaofeng52_800_3"},{"subj":"T10","pred":"source","obj":"maxiaofeng52_800_3"}]},{"project":"wangzhuo19_800_3","denotations":[{"id":"T1","span":{"begin":620,"end":633},"obj":"DP"},{"id":"T2","span":{"begin":202,"end":215},"obj":"DP"},{"id":"T3","span":{"begin":352,"end":365},"obj":"DP"},{"id":"T4","span":{"begin":406,"end":419},"obj":"DP"},{"id":"T5","span":{"begin":696,"end":707},"obj":"CI"},{"id":"T6","span":{"begin":709,"end":721},"obj":"CI"},{"id":"T7","span":{"begin":727,"end":737},"obj":"CI"},{"id":"T8","span":{"begin":26,"end":39},"obj":"DP"},{"id":"T9","span":{"begin":76,"end":89},"obj":"DP"},{"id":"T10","span":{"begin":508,"end":521},"obj":"DP"}],"attributes":[{"subj":"T1","pred":"source","obj":"wangzhuo19_800_3"},{"subj":"T2","pred":"source","obj":"wangzhuo19_800_3"},{"subj":"T3","pred":"source","obj":"wangzhuo19_800_3"},{"subj":"T4","pred":"source","obj":"wangzhuo19_800_3"},{"subj":"T5","pred":"source","obj":"wangzhuo19_800_3"},{"subj":"T6","pred":"source","obj":"wangzhuo19_800_3"},{"subj":"T7","pred":"source","obj":"wangzhuo19_800_3"},{"subj":"T8","pred":"source","obj":"wangzhuo19_800_3"},{"subj":"T9","pred":"source","obj":"wangzhuo19_800_3"},{"subj":"T10","pred":"source","obj":"wangzhuo19_800_3"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubmedHPO","color":"#93eceb","default":true},{"id":"maxiaofeng52_800_3","color":"#ecd193"},{"id":"wangzhuo19_800_3","color":"#b693ec"}]}]}}