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PubMed:25452134 / 0-1770 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-109 Sentence denotes Quantitative proteome analysis of Caenorhabditis elegans upon exposure to nematicidal Bacillus thuringiensis.
T2 110-121 Sentence denotes UNLABELLED:
T3 122-233 Sentence denotes Caenorhabditis elegans can be infected by a plethora of pathogens, most of them are also pathogenic for humans.
T4 234-432 Sentence denotes Consequently, the nematode has emerged as a powerful surrogate host to model microbial human infectious diseases in a non-vertebrate, for the study of innate immunity and host-pathogen interactions.
T5 433-514 Sentence denotes Signaling cascades are well investigated that face bacterial or fungal pathogens.
T6 515-784 Sentence denotes We analyzed the downstream processes of these cascades, i.e. the differential expression of effector and regulatory molecules due to a microbial challenge with a pathogenic strain of the bacterium Bacillus thuringiensis (Bt) in comparison to a non-pathogenic Bt strain.
T7 785-913 Sentence denotes The protein abundance profile of the nematode was studied by quantitative proteomics using iTRAQ labeling and 2D-LC-MS analysis.
T8 914-1153 Sentence denotes We developed (i) a novel method for the preparation of defined C. elegans samples; (ii) a pooling strategy for fractions in 2D-LC separation schemes; and (iii) an isobaric labeling scheme reducing the number of necessary LC-MS experiments.
T9 1154-1377 Sentence denotes More than 3,600 proteins were quantified, 288 of which showed altered abundances, implicating protein classes such as lectins, lysozymes, and transthyretin-like proteins to be involved in the nematode innate immune defense.
T10 1378-1498 Sentence denotes A number of gene products previously only identified by transcriptomic profiling could be verified at the protein level.
T11 1499-1686 Sentence denotes Moreover, several other protein classes such as proteases, proteins related to autophagy and apoptosis, structural proteins, and proteins involved in chromatin organization were detected.
T1 0-109 Sentence denotes Quantitative proteome analysis of Caenorhabditis elegans upon exposure to nematicidal Bacillus thuringiensis.
T2 110-121 Sentence denotes UNLABELLED:
T3 122-233 Sentence denotes Caenorhabditis elegans can be infected by a plethora of pathogens, most of them are also pathogenic for humans.
T4 234-432 Sentence denotes Consequently, the nematode has emerged as a powerful surrogate host to model microbial human infectious diseases in a non-vertebrate, for the study of innate immunity and host-pathogen interactions.
T5 433-514 Sentence denotes Signaling cascades are well investigated that face bacterial or fungal pathogens.
T6 515-784 Sentence denotes We analyzed the downstream processes of these cascades, i.e. the differential expression of effector and regulatory molecules due to a microbial challenge with a pathogenic strain of the bacterium Bacillus thuringiensis (Bt) in comparison to a non-pathogenic Bt strain.
T7 785-913 Sentence denotes The protein abundance profile of the nematode was studied by quantitative proteomics using iTRAQ labeling and 2D-LC-MS analysis.
T8 914-1153 Sentence denotes We developed (i) a novel method for the preparation of defined C. elegans samples; (ii) a pooling strategy for fractions in 2D-LC separation schemes; and (iii) an isobaric labeling scheme reducing the number of necessary LC-MS experiments.
T9 1154-1377 Sentence denotes More than 3,600 proteins were quantified, 288 of which showed altered abundances, implicating protein classes such as lectins, lysozymes, and transthyretin-like proteins to be involved in the nematode innate immune defense.
T10 1378-1498 Sentence denotes A number of gene products previously only identified by transcriptomic profiling could be verified at the protein level.
T11 1499-1686 Sentence denotes Moreover, several other protein classes such as proteases, proteins related to autophagy and apoptosis, structural proteins, and proteins involved in chromatin organization were detected.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 356-366 http://purl.obolibrary.org/obo/MAT_0000373 denotes vertebrate

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 166-174 HP_0001050 denotes plethora

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 327-337 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 356-366 Body_part denotes vertebrate http://purl.obolibrary.org/obo/MAT_0000373

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 166-174 Phenotype denotes plethora HP:0001050

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 34-56 OrganismTaxon denotes Caenorhabditis elegans 6239
T2 86-108 OrganismTaxon denotes Bacillus thuringiensis 1428
T3 122-144 OrganismTaxon denotes Caenorhabditis elegans 6239
T4 252-260 OrganismTaxon denotes nematode 6231
T5 321-326 OrganismTaxon denotes human 9606
T6 712-734 OrganismTaxon denotes Bacillus thuringiensis 1428
T7 736-738 OrganismTaxon denotes Bt 1428
T8 774-776 OrganismTaxon denotes Bt 1428
T9 822-830 OrganismTaxon denotes nematode 6231
T10 1346-1354 OrganismTaxon denotes nematode 6231

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 479-483 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456