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PubMed:2538431 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-78 Sentence denotes Ca2+/calmodulin-dependent protein kinase enriched in cerebellar granule cells.
T2 79-150 Sentence denotes Identification of a novel neuronal calmodulin-dependent protein kinase.
T3 151-257 Sentence denotes Ca2+-sensitive protein kinases are thought to play a pivotal role in Ca2+-mediated neuronal communication.
T4 258-450 Sentence denotes We describe here the cloning, purification, and characterization of a major Ca2+/calmodulin-dependent, brain-specific protein kinase which is particularly enriched in cerebellar granule cells.
T5 451-571 Sentence denotes The enzyme is comprised of Mr 65,000 and 67,000 polypeptides which copurify to homogeneity and phosphorylate synapsin I.
T6 572-691 Sentence denotes The protein kinase is coded for by two poly(A+) RNAs of 2.0 and 3.5 kilobases which probably derive from a single gene.
T7 692-955 Sentence denotes Two cDNA inserts, one of 198 base pairs and one of 1225 base pairs, contain a total of 677 base pairs of the protein coding sequence which includes sequences homologous to other calmodulin-dependent protein kinases including part of the calmodulin-binding domain.
T8 956-1101 Sentence denotes The surprising presence of extended sequences which are enriched in glutamate residues may influence the subcellular distribution of this kinase.
T9 1102-1319 Sentence denotes Immunohistochemical localization with an affinity-purified antibody reveals that whereas the enzyme is expressed in several neuronal subpopulations, it is exceptionally enriched in the granule cells of the cerebellum.
T10 1320-1461 Sentence denotes The relevance of the biochemical, molecular, and histologic properties of this enzyme is discussed in the context of neuronal Ca2+ signaling.
T1 0-78 Sentence denotes Ca2+/calmodulin-dependent protein kinase enriched in cerebellar granule cells.
T2 79-150 Sentence denotes Identification of a novel neuronal calmodulin-dependent protein kinase.
T3 151-257 Sentence denotes Ca2+-sensitive protein kinases are thought to play a pivotal role in Ca2+-mediated neuronal communication.
T4 258-450 Sentence denotes We describe here the cloning, purification, and characterization of a major Ca2+/calmodulin-dependent, brain-specific protein kinase which is particularly enriched in cerebellar granule cells.
T5 451-571 Sentence denotes The enzyme is comprised of Mr 65,000 and 67,000 polypeptides which copurify to homogeneity and phosphorylate synapsin I.
T6 572-691 Sentence denotes The protein kinase is coded for by two poly(A+) RNAs of 2.0 and 3.5 kilobases which probably derive from a single gene.
T7 692-955 Sentence denotes Two cDNA inserts, one of 198 base pairs and one of 1225 base pairs, contain a total of 677 base pairs of the protein coding sequence which includes sequences homologous to other calmodulin-dependent protein kinases including part of the calmodulin-binding domain.
T8 956-1101 Sentence denotes The surprising presence of extended sequences which are enriched in glutamate residues may influence the subcellular distribution of this kinase.
T9 1102-1319 Sentence denotes Immunohistochemical localization with an affinity-purified antibody reveals that whereas the enzyme is expressed in several neuronal subpopulations, it is exceptionally enriched in the granule cells of the cerebellum.
T10 1320-1461 Sentence denotes The relevance of the biochemical, molecular, and histologic properties of this enzyme is discussed in the context of neuronal Ca2+ signaling.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 361-366 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T2 1308-1318 http://purl.obolibrary.org/obo/MAT_0000110 denotes cerebellum

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 361-366 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T2 1308-1318 Body_part denotes cerebellum http://purl.obolibrary.org/obo/MAT_0000110

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 53-77 Body_part denotes cerebellar granule cells http://purl.obolibrary.org/obo/CL_0001031
T2 361-366 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T4 425-449 Body_part denotes cerebellar granule cells http://purl.obolibrary.org/obo/CL_0001031
T5 1287-1318 Body_part denotes granule cells of the cerebellum http://purl.obolibrary.org/obo/CL_0001031

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 53-77 Cell denotes cerebellar granule cells http://purl.obolibrary.org/obo/CL:0001031
T2 105-113 Cell denotes neuronal http://purl.obolibrary.org/obo/CL:0000540
T3 234-242 Cell denotes neuronal http://purl.obolibrary.org/obo/CL:0000540
T4 425-449 Cell denotes cerebellar granule cells http://purl.obolibrary.org/obo/CL:0001031
T5 611-615 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T7 1226-1234 Cell denotes neuronal http://purl.obolibrary.org/obo/CL:0000540
T8 1287-1318 Cell denotes granule cells of the cerebellum http://purl.obolibrary.org/obo/CL:0001031
T9 1437-1445 Cell denotes neuronal http://purl.obolibrary.org/obo/CL:0000540