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PubMed:25371208 JSON TXT

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silkworm_phenotype

Id	Subject	Object	Predicate	Lexical cue
T8	1208-1213	Gene:100415910	denotes	Kr-h1
T9	1318-1325	Gene:100415910	denotes	BmKr-h1
T7	1104-1111	Species:7091	denotes	B. mori
T6	702-707	Gene:693030	denotes	fib-H
T5	648-653	Gene:693030	denotes	fib-H
T4	631-646	Gene:693030	denotes	fibroin H-chain
T3	252-263	Species:7091	denotes	Bombyx mori
T28	1474-1489	BMO_00547	denotes	fibroin H-chain
T26	1432-1437	BMO_00547	denotes	fib-H
T20	702-707	BMO_00547	denotes	fib-H
T2	129-140	Species:7091	denotes	Bombyx mori
T17	648-653	BMO_00547	denotes	fib-H
T15	631-646	BMO_00547	denotes	fibroin H-chain
T13	47-62	BMO_00547	denotes	fibroin H chain
T12	1501-1508	Species:7091	denotes	B. mori
T11	1474-1489	Gene:693030	denotes	fibroin H-chain
T10	1432-1437	Gene:693030	denotes	fib-H
T1	119-127	Species:7091	denotes	silkworm

sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-141	Sentence	denotes	A juvenile hormone transcription factor Bmdimm-fibroin H chain pathway is involved in the synthesis of silk protein in silkworm, Bombyx mori.
T2	142-264	Sentence	denotes	The genes responsible for silk biosynthesis are switched on and off at particular times in the silk glands of Bombyx mori.
T3	265-346	Sentence	denotes	This switch appears to be under the control of endogenous and exogenous hormones.
T4	347-475	Sentence	denotes	However, the molecular mechanisms by which silk protein synthesis is regulated by the juvenile hormone (JH) are largely unknown.
T5	476-722	Sentence	denotes	Here, we report a basic helix-loop-helix transcription factor, Bmdimm, its silk gland-specific expression, and its direct involvement in the regulation of fibroin H-chain (fib-H) by binding to an E-box (CAAATG) element of the fib-H gene promoter.
T6	723-917	Sentence	denotes	Far-Western blots, enzyme-linked immunosorbent assays, and co-immunoprecipitation assays revealed that Bmdimm protein interacted with another basic helix-loop-helix transcription factor, Bmsage.
T7	918-1001	Sentence	denotes	Immunostaining revealed that Bmdimm and Bmsage proteins are co-localized in nuclei.
T8	1002-1156	Sentence	denotes	Bmdimm expression was induced in larval silk glands in vivo, in silk glands cultured in vitro, and in B. mori cell lines after treatment with a JH analog.
T9	1157-1330	Sentence	denotes	The JH effect on Bmdimm was mediated by the JH-Met-Kr-h1 signaling pathway, and Bmdimm expression did not respond to JH by RNA interference with double-stranded BmKr-h1 RNA.
T10	1331-1509	Sentence	denotes	These data suggest that the JH regulatory pathway, the transcription factor Bmdimm, and the targeted fib-H gene contribute to the synthesis of fibroin H-chain protein in B. mori.

Glycosmos6-MAT

Id	Subject	Object	Predicate	Lexical cue
T1	242-248	http://purl.obolibrary.org/obo/MAT_0000021	denotes	glands
T2	556-561	http://purl.obolibrary.org/obo/MAT_0000021	denotes	gland
T3	1047-1053	http://purl.obolibrary.org/obo/MAT_0000021	denotes	glands
T4	1071-1077	http://purl.obolibrary.org/obo/MAT_0000021	denotes	glands

silkworm

Id	Subject	Object	Predicate	Lexical cue
T1	119-127	Species:7091	denotes	silkworm
T2	129-140	Species:7091	denotes	Bombyx mori
T3	252-263	Species:7091	denotes	Bombyx mori
T4	631-646	Gene:693030	denotes	fibroin H-chain
T5	648-653	Gene:693030	denotes	fib-H
T6	702-707	Gene:693030	denotes	fib-H
T7	1104-1111	Species:7091	denotes	B. mori
T8	1208-1213	Gene:100415910	denotes	Kr-h1
T9	1318-1325	Gene:100415910	denotes	BmKr-h1
T10	1432-1437	Gene:693030	denotes	fib-H
T11	1474-1489	Gene:693030	denotes	fibroin H-chain
T12	1501-1508	Species:7091	denotes	B. mori

silkwormbase

Id	Subject	Object	Predicate	Lexical cue
T1	119-127	Species:7091	denotes	silkworm
T10	1432-1437	Gene:693030	denotes	fib-H
T11	1474-1489	Gene:693030	denotes	fibroin H-chain
T12	1501-1508	Species:7091	denotes	B. mori
T13	47-62	BMO_00547	denotes	fibroin H chain
T15	631-646	BMO_00547	denotes	fibroin H-chain
T17	648-653	BMO_00547	denotes	fib-H
T2	129-140	Species:7091	denotes	Bombyx mori
T20	702-707	BMO_00547	denotes	fib-H
T26	1432-1437	BMO_00547	denotes	fib-H
T28	1474-1489	BMO_00547	denotes	fibroin H-chain
T3	252-263	Species:7091	denotes	Bombyx mori
T4	631-646	Gene:693030	denotes	fibroin H-chain
T5	648-653	Gene:693030	denotes	fib-H
T6	702-707	Gene:693030	denotes	fib-H
T7	1104-1111	Species:7091	denotes	B. mori
T9	1318-1325	Gene:100415910	denotes	BmKr-h1
T8	1208-1213	Gene:100415910	denotes	Kr-h1

Anatomy-MAT

Id	Subject	Object	Predicate	Lexical cue	mat_id
T1	242-248	Body_part	denotes	glands	http://purl.obolibrary.org/obo/MAT_0000021
T2	556-561	Body_part	denotes	gland	http://purl.obolibrary.org/obo/MAT_0000021
T3	1047-1053	Body_part	denotes	glands	http://purl.obolibrary.org/obo/MAT_0000021
T4	1071-1077	Body_part	denotes	glands	http://purl.obolibrary.org/obo/MAT_0000021

NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	119-127	OrganismTaxon	denotes	silkworm	7091
T2	129-140	OrganismTaxon	denotes	Bombyx mori	7091
T3	252-263	OrganismTaxon	denotes	Bombyx mori	7091

Anatomy-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	2-10	Body_part	denotes	juvenile	http://purl.obolibrary.org/obo/UBERON_0007021
T2	103-107	Body_part	denotes	silk	http://purl.obolibrary.org/obo/UBERON_0012245
T3	168-172	Body_part	denotes	silk	http://purl.obolibrary.org/obo/UBERON_0012245
T4	237-248	Body_part	denotes	silk glands	http://purl.obolibrary.org/obo/UBERON_0011146
T5	390-394	Body_part	denotes	silk	http://purl.obolibrary.org/obo/UBERON_0012245
T6	433-441	Body_part	denotes	juvenile	http://purl.obolibrary.org/obo/UBERON_0007021
T7	500-505	Body_part	denotes	helix	http://purl.obolibrary.org/obo/UBERON_0002488
T8	511-516	Body_part	denotes	helix	http://purl.obolibrary.org/obo/UBERON_0002488
T9	551-561	Body_part	denotes	silk gland	http://purl.obolibrary.org/obo/UBERON_0011146
T10	871-876	Body_part	denotes	helix	http://purl.obolibrary.org/obo/UBERON_0002488
T11	882-887	Body_part	denotes	helix	http://purl.obolibrary.org/obo/UBERON_0002488
T12	1042-1053	Body_part	denotes	silk glands	http://purl.obolibrary.org/obo/UBERON_0011146
T13	1066-1077	Body_part	denotes	silk glands	http://purl.obolibrary.org/obo/UBERON_0011146