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PubMed:25347993 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-119 Sentence denotes Differentially expressed glycosylated patterns of α-1-antitrypsin as serum biomarkers for the diagnosis of lung cancer.
TextSentencer_T2 120-172 Sentence denotes Lung cancer is the most common malignancy worldwide.
TextSentencer_T3 173-298 Sentence denotes Thus, there is a critical need for diagnostic biomarkers with adequate sensitivity and specificity for lung cancer detection.
TextSentencer_T4 299-433 Sentence denotes Glycans in glycoproteins are significantly altered in cancer, and may serve as a tool for identifying potential diagnostic biomarkers.
TextSentencer_T5 434-555 Sentence denotes Recent studies have reported changes in α-1-antitrypsin (A1AT) glycosylation in lung cancer serum, tissue and cell lines.
TextSentencer_T6 556-779 Sentence denotes In this study, a lectin microarray was used to detect glycosylation changes in serum A1AT from patients with lung adenocarcinoma (ADC), squamous cell lung cancer, small-cell lung cancer (SCLC) and benign pulmonary diseases.
TextSentencer_T7 780-945 Sentence denotes Differentially expressed glycosylated patterns of A1AT were identified by lectin arrays and were confirmed by lectin-based enzyme-linked immunosorbent assay (ELISA).
TextSentencer_T8 946-1336 Sentence denotes We found that galactosylated A1AT could distinguish non-small-cell lung cancer (NSCLC) from benign pulmonary diseases (AUC = 0.834); fucosylated A1AT showed exceptional capability in distinguishing ADC from benign diseases (AUC = 0.919) or other lung cancer subtypes (AUC = 0.844), and A1AT containing poly-LacNAc could detect SCLC from benign diseases (AUC = 0.905) or NSCLC (AUC = 0.707).
TextSentencer_T9 1337-1463 Sentence denotes The present study indicates that glycosylated patterns of A1AT may serve as potential biomarkers for detection of lung cancer.
TextSentencer_T10 1464-1567 Sentence denotes Further studies in larger sample sizes are necessary to validate the clinical utility of these markers.
T1 0-119 Sentence denotes Differentially expressed glycosylated patterns of α-1-antitrypsin as serum biomarkers for the diagnosis of lung cancer.
T2 120-172 Sentence denotes Lung cancer is the most common malignancy worldwide.
T3 173-298 Sentence denotes Thus, there is a critical need for diagnostic biomarkers with adequate sensitivity and specificity for lung cancer detection.
T4 299-433 Sentence denotes Glycans in glycoproteins are significantly altered in cancer, and may serve as a tool for identifying potential diagnostic biomarkers.
T5 434-555 Sentence denotes Recent studies have reported changes in α-1-antitrypsin (A1AT) glycosylation in lung cancer serum, tissue and cell lines.
T6 556-779 Sentence denotes In this study, a lectin microarray was used to detect glycosylation changes in serum A1AT from patients with lung adenocarcinoma (ADC), squamous cell lung cancer, small-cell lung cancer (SCLC) and benign pulmonary diseases.
T7 780-945 Sentence denotes Differentially expressed glycosylated patterns of A1AT were identified by lectin arrays and were confirmed by lectin-based enzyme-linked immunosorbent assay (ELISA).
T8 946-1336 Sentence denotes We found that galactosylated A1AT could distinguish non-small-cell lung cancer (NSCLC) from benign pulmonary diseases (AUC = 0.834); fucosylated A1AT showed exceptional capability in distinguishing ADC from benign diseases (AUC = 0.919) or other lung cancer subtypes (AUC = 0.844), and A1AT containing poly-LacNAc could detect SCLC from benign diseases (AUC = 0.905) or NSCLC (AUC = 0.707).
T9 1337-1463 Sentence denotes The present study indicates that glycosylated patterns of A1AT may serve as potential biomarkers for detection of lung cancer.
T10 1464-1567 Sentence denotes Further studies in larger sample sizes are necessary to validate the clinical utility of these markers.
T1 0-119 Sentence denotes Differentially expressed glycosylated patterns of α-1-antitrypsin as serum biomarkers for the diagnosis of lung cancer.
T2 120-172 Sentence denotes Lung cancer is the most common malignancy worldwide.
T3 173-298 Sentence denotes Thus, there is a critical need for diagnostic biomarkers with adequate sensitivity and specificity for lung cancer detection.
T4 299-433 Sentence denotes Glycans in glycoproteins are significantly altered in cancer, and may serve as a tool for identifying potential diagnostic biomarkers.
T5 434-555 Sentence denotes Recent studies have reported changes in α-1-antitrypsin (A1AT) glycosylation in lung cancer serum, tissue and cell lines.
T6 556-779 Sentence denotes In this study, a lectin microarray was used to detect glycosylation changes in serum A1AT from patients with lung adenocarcinoma (ADC), squamous cell lung cancer, small-cell lung cancer (SCLC) and benign pulmonary diseases.
T7 780-945 Sentence denotes Differentially expressed glycosylated patterns of A1AT were identified by lectin arrays and were confirmed by lectin-based enzyme-linked immunosorbent assay (ELISA).
T8 946-1336 Sentence denotes We found that galactosylated A1AT could distinguish non-small-cell lung cancer (NSCLC) from benign pulmonary diseases (AUC = 0.834); fucosylated A1AT showed exceptional capability in distinguishing ADC from benign diseases (AUC = 0.919) or other lung cancer subtypes (AUC = 0.844), and A1AT containing poly-LacNAc could detect SCLC from benign diseases (AUC = 0.905) or NSCLC (AUC = 0.707).
T9 1337-1463 Sentence denotes The present study indicates that glycosylated patterns of A1AT may serve as potential biomarkers for detection of lung cancer.
T10 1464-1567 Sentence denotes Further studies in larger sample sizes are necessary to validate the clinical utility of these markers.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 107-111 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T2 120-124 http://purl.obolibrary.org/obo/MAT_0000135 denotes Lung
T3 276-280 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T4 514-518 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T5 665-669 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T6 706-710 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T7 730-734 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T8 1013-1017 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T9 1192-1196 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T10 1451-1455 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 120-131 HP_0100526 denotes Lung cancer
T2 125-131 HP_0002664 denotes cancer
T3 276-287 HP_0100526 denotes lung cancer
T4 281-287 HP_0002664 denotes cancer
T5 353-359 HP_0002664 denotes cancer
T6 514-525 HP_0100526 denotes lung cancer
T7 519-525 HP_0002664 denotes cancer
T8 665-684 HP_0030078 denotes lung adenocarcinoma
T9 706-717 HP_0100526 denotes lung cancer
T10 711-717 HP_0002664 denotes cancer
T11 719-741 HP_0030357 denotes small-cell lung cancer
T12 730-741 HP_0100526 denotes lung cancer
T13 735-741 HP_0002664 denotes cancer
T14 998-1024 HP_0030358 denotes non-small-cell lung cancer
T15 1002-1024 HP_0030357 denotes small-cell lung cancer
T16 1013-1024 HP_0100526 denotes lung cancer
T17 1018-1024 HP_0002664 denotes cancer
T18 1192-1203 HP_0100526 denotes lung cancer
T19 1197-1203 HP_0002664 denotes cancer
T20 1451-1462 HP_0100526 denotes lung cancer
T21 1456-1462 HP_0002664 denotes cancer

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 69-74 FMAID:167330 denotes serum
_T2 107-111 FMAID:93670 denotes lung
_T3 107-111 FMAID:7195 denotes lung
_T4 107-111 FMAID:169341 denotes lung
_T5 120-124 FMAID:169341 denotes Lung
_T6 120-124 FMAID:93670 denotes Lung
_T7 120-124 FMAID:7195 denotes Lung
_T8 276-280 FMAID:93670 denotes lung
_T9 276-280 FMAID:169341 denotes lung
_T10 276-280 FMAID:7195 denotes lung
_T11 310-323 FMAID:62925 denotes glycoproteins
_T12 310-323 FMAID:167256 denotes glycoproteins
_T13 514-518 FMAID:7195 denotes lung
_T14 514-518 FMAID:93670 denotes lung
_T15 514-518 FMAID:169341 denotes lung
_T16 526-531 FMAID:167330 denotes serum
_T17 533-539 FMAID:256050 denotes tissue
_T18 540-548 FMAID:200932 denotes and cell
_T19 540-548 FMAID:86471 denotes and cell
_T20 635-640 FMAID:167330 denotes serum
_T21 665-669 FMAID:169341 denotes lung
_T22 665-669 FMAID:93670 denotes lung
_T23 665-669 FMAID:7195 denotes lung
_T24 692-700 FMAID:70633 denotes squamous
_T25 692-700 FMAID:171491 denotes squamous
_T26 692-705 FMAID:66769 denotes squamous cell
_T27 692-705 FMAID:201938 denotes squamous cell
_T28 692-705 FMAID:164923 denotes squamous cell
_T29 706-710 FMAID:93670 denotes lung
_T30 706-710 FMAID:169341 denotes lung
_T31 706-710 FMAID:7195 denotes lung
_T32 719-729 FMAID:199060 denotes small-cell
_T33 730-734 FMAID:7195 denotes lung
_T34 730-734 FMAID:169341 denotes lung
_T35 730-734 FMAID:93670 denotes lung
_T36 760-769 FMAID:66326 denotes pulmonary
_T37 760-769 FMAID:171535 denotes pulmonary
_T38 1002-1012 FMAID:199060 denotes small-cell
_T39 1013-1017 FMAID:169341 denotes lung
_T40 1013-1017 FMAID:93670 denotes lung
_T41 1013-1017 FMAID:7195 denotes lung
_T42 1045-1054 FMAID:66326 denotes pulmonary
_T43 1045-1054 FMAID:171535 denotes pulmonary
_T44 1192-1196 FMAID:169341 denotes lung
_T45 1192-1196 FMAID:93670 denotes lung
_T46 1192-1196 FMAID:7195 denotes lung
_T47 1451-1455 FMAID:169341 denotes lung
_T48 1451-1455 FMAID:93670 denotes lung
_T49 1451-1455 FMAID:7195 denotes lung

uniprot-human

Id Subject Object Predicate Lexical cue
T1 50-65 http://www.uniprot.org/uniprot/Q86U18 denotes α-1-antitrypsin
T2 474-489 http://www.uniprot.org/uniprot/Q86U18 denotes α-1-antitrypsin
T3 686-689 http://www.uniprot.org/uniprot/Q6ZQY3 denotes ADC
T4 1144-1147 http://www.uniprot.org/uniprot/Q6ZQY3 denotes ADC
T5 686-689 http://www.uniprot.org/uniprot/Q96L55 denotes ADC
T6 1144-1147 http://www.uniprot.org/uniprot/Q96L55 denotes ADC

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 686-689 http://www.uniprot.org/uniprot/Q80WP8 denotes ADC
T2 1144-1147 http://www.uniprot.org/uniprot/Q80WP8 denotes ADC
T3 686-689 http://www.uniprot.org/uniprot/Q8BVM4 denotes ADC
T4 1144-1147 http://www.uniprot.org/uniprot/Q8BVM4 denotes ADC

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 112-118 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T2 125-131 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T3 281-287 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T4 353-359 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T5 519-525 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T6 533-539 http://purl.bioontology.org/ontology/STY/T024 denotes tissue
T7 711-717 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T8 735-741 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T9 760-769 http://purl.bioontology.org/ontology/NCBITAXON/136615 denotes pulmonary
T10 998-1001 http://purl.bioontology.org/ontology/NCBITAXON/604139 denotes non
T11 1018-1024 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T12 1045-1054 http://purl.bioontology.org/ontology/NCBITAXON/136615 denotes pulmonary
T13 1197-1203 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer
T14 1456-1462 http://purl.bioontology.org/ontology/NCBITAXON/6754 denotes cancer

GO-BP

Id Subject Object Predicate Lexical cue
T1 25-37 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylated
T2 805-817 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylated
T3 497-510 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T4 610-623 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T5 244-255 http://purl.obolibrary.org/obo/GO_0046960 denotes sensitivity
T6 260-280 http://purl.obolibrary.org/obo/GO_0060424 denotes specificity for lung
T7 1079-1090 http://purl.obolibrary.org/obo/GO_0036065 denotes fucosylated

GO-CC

Id Subject Object Predicate Lexical cue
T1 544-548 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 701-705 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 725-729 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T4 1008-1012 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 69-74 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T2 526-531 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T3 635-640 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T4 107-111 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T5 276-280 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T6 514-518 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T7 665-669 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T8 706-710 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T9 730-734 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T10 1013-1017 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T11 1192-1196 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T12 1451-1455 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T13 533-539 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 75-85 http://edamontology.org/topic_3360 denotes biomarkers
T2 112-118 http://edamontology.org/topic_2640 denotes cancer
T3 125-131 http://edamontology.org/topic_2640 denotes cancer
T4 219-229 http://edamontology.org/topic_3360 denotes biomarkers
T5 281-287 http://edamontology.org/topic_2640 denotes cancer
T6 353-359 http://edamontology.org/topic_2640 denotes cancer
T7 422-432 http://edamontology.org/topic_3360 denotes biomarkers
T8 441-448 http://edamontology.org/topic_3678 denotes studies
T9 519-525 http://edamontology.org/topic_2640 denotes cancer
T10 564-569 http://edamontology.org/topic_3678 denotes study
T11 580-590 http://edamontology.org/topic_3518 denotes microarray
T12 580-590 http://edamontology.org/topic_0200 denotes microarray
T13 711-717 http://edamontology.org/topic_2640 denotes cancer
T14 735-741 http://edamontology.org/topic_2640 denotes cancer
T15 770-778 http://edamontology.org/topic_0634 denotes diseases
T16 1018-1024 http://edamontology.org/topic_2640 denotes cancer
T17 1055-1063 http://edamontology.org/topic_0634 denotes diseases
T18 1160-1168 http://edamontology.org/topic_0634 denotes diseases
T19 1197-1203 http://edamontology.org/topic_2640 denotes cancer
T20 1290-1298 http://edamontology.org/topic_0634 denotes diseases
T21 1349-1354 http://edamontology.org/topic_3678 denotes study
T22 1423-1433 http://edamontology.org/topic_3360 denotes biomarkers
T23 1456-1462 http://edamontology.org/topic_2640 denotes cancer
T24 1472-1479 http://edamontology.org/topic_3678 denotes studies
T25 1490-1496 http://edamontology.org/topic_3277 denotes sample

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 0-24 http://edamontology.org/operation_3742 denotes Differentially expressed
T2 288-297 http://edamontology.org/operation_2423 denotes detection
T3 380-384 http://edamontology.org/data_0007 denotes tool
T4 380-400 http://edamontology.org/data_0977 denotes tool for identifying
T5 385-400 http://edamontology.org/data_3358 denotes for identifying
T6 389-400 http://edamontology.org/data_0842 denotes identifying
T7 389-400 http://edamontology.org/data_2611 denotes identifying
T8 454-462 http://edamontology.org/data_2048 denotes reported
T9 580-594 http://edamontology.org/data_2603 denotes microarray was
T10 603-609 http://edamontology.org/operation_2423 denotes detect
T11 780-804 http://edamontology.org/operation_3742 denotes Differentially expressed
T12 840-850 http://edamontology.org/data_0842 denotes identified
T13 840-850 http://edamontology.org/data_2611 denotes identified
T14 861-867 http://edamontology.org/data_2082 denotes arrays
T15 1266-1272 http://edamontology.org/operation_2423 denotes detect
T16 1438-1447 http://edamontology.org/operation_2423 denotes detection
T17 1520-1528 http://edamontology.org/operation_2428 denotes validate

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 107-111 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T2 120-124 http://purl.obolibrary.org/obo/MAT_0000135 denotes Lung
T3 276-280 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T4 514-518 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T5 665-669 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T6 706-710 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T7 730-734 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T8 1013-1017 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T9 1192-1196 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T10 1451-1455 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung

GlyTouCan-IUPAC

Id Subject Object Predicate Lexical cue
GlycanIUPAC_T1 998-1001 "http://rdf.glycoinfo.org/glycan/G02780QX" denotes non
GlycanIUPAC_T2 998-1001 "http://rdf.glycoinfo.org/glycan/G18425DX" denotes non
GlycanIUPAC_T3 998-1001 "http://rdf.glycoinfo.org/glycan/G18630JE" denotes non
GlycanIUPAC_T4 998-1001 "http://rdf.glycoinfo.org/glycan/G01004IT" denotes non
GlycanIUPAC_T5 998-1001 "http://rdf.glycoinfo.org/glycan/G87301QZ" denotes non
GlycanIUPAC_T6 998-1001 "http://rdf.glycoinfo.org/glycan/G39790GW" denotes non
GlycanIUPAC_T7 998-1001 "http://rdf.glycoinfo.org/glycan/G42928BB" denotes non
GlycanIUPAC_T8 998-1001 "http://rdf.glycoinfo.org/glycan/G51134HC" denotes non
GlycanIUPAC_T9 998-1001 "http://rdf.glycoinfo.org/glycan/G68183GR" denotes non
GlycanIUPAC_T10 998-1001 "http://rdf.glycoinfo.org/glycan/G46883FA" denotes non
GlycanIUPAC_T11 998-1001 "http://rdf.glycoinfo.org/glycan/G54702VY" denotes non

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 107-111 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T2 120-124 http://purl.obolibrary.org/obo/UBERON_0002048 denotes Lung
PD-UBERON-AE-B_T3 276-280 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T4 514-518 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T5 665-669 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T6 706-710 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T7 730-734 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T8 1013-1017 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T9 1192-1196 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T10 1451-1455 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T11 533-539 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T12 69-74 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T13 526-531 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
PD-UBERON-AE-B_T14 635-640 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 1253-1259 Glycan denotes LacNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G66213AR

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 107-111 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T2 120-124 Body_part denotes Lung http://purl.obolibrary.org/obo/MAT_0000135
T3 276-280 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T4 514-518 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T5 665-669 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T6 706-710 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T7 730-734 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T8 1013-1017 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T9 1192-1196 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T10 1451-1455 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 107-118 Phenotype denotes lung cancer HP:0100526
T2 120-131 Phenotype denotes Lung cancer HP:0100526
T3 276-287 Phenotype denotes lung cancer HP:0100526
T4 353-359 Phenotype denotes cancer HP:0002664
T5 514-525 Phenotype denotes lung cancer HP:0100526
T6 665-684 Phenotype denotes lung adenocarcinoma HP:0030078
T7 706-717 Phenotype denotes lung cancer HP:0100526
T8 719-741 Phenotype denotes small-cell lung cancer HP:0030357
T9 743-747 Phenotype denotes SCLC HP:0030357
T10 998-1024 Phenotype denotes non-small-cell lung cancer HP:0030358
T11 1026-1031 Phenotype denotes NSCLC HP:0030358
T12 1192-1203 Phenotype denotes lung cancer HP:0100526
T13 1273-1277 Phenotype denotes SCLC HP:0030357
T14 1316-1321 Phenotype denotes NSCLC HP:0030358
T15 1451-1462 Phenotype denotes lung cancer HP:0100526

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 107-118 Disease denotes lung cancer http://purl.obolibrary.org/obo/MONDO_0008903
T2 120-131 Disease denotes Lung cancer http://purl.obolibrary.org/obo/MONDO_0008903
T3 276-287 Disease denotes lung cancer http://purl.obolibrary.org/obo/MONDO_0008903
T4 353-359 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T5 514-525 Disease denotes lung cancer http://purl.obolibrary.org/obo/MONDO_0008903
T6 665-684 Disease denotes lung adenocarcinoma http://purl.obolibrary.org/obo/MONDO_0005061
T7 686-689 Disease denotes ADC http://purl.obolibrary.org/obo/MONDO_0020689|http://purl.obolibrary.org/obo/MONDO_0004970
T9 692-717 Disease denotes squamous cell lung cancer http://purl.obolibrary.org/obo/MONDO_0005097
T10 719-741 Disease denotes small-cell lung cancer http://purl.obolibrary.org/obo/MONDO_0008433
T11 743-747 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433
T12 760-778 Disease denotes pulmonary diseases http://purl.obolibrary.org/obo/MONDO_0005275
T13 998-1024 Disease denotes non-small-cell lung cancer http://purl.obolibrary.org/obo/MONDO_0005233
T14 1026-1031 Disease denotes NSCLC http://purl.obolibrary.org/obo/MONDO_0005233
T15 1045-1063 Disease denotes pulmonary diseases http://purl.obolibrary.org/obo/MONDO_0005275
T16 1144-1147 Disease denotes ADC http://purl.obolibrary.org/obo/MONDO_0020689|http://purl.obolibrary.org/obo/MONDO_0004970
T18 1192-1203 Disease denotes lung cancer http://purl.obolibrary.org/obo/MONDO_0008903
T19 1273-1277 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433
T20 1316-1321 Disease denotes NSCLC http://purl.obolibrary.org/obo/MONDO_0005233
T21 1451-1462 Disease denotes lung cancer http://purl.obolibrary.org/obo/MONDO_0008903

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 107-118 Phenotype denotes lung cancer HP:0100526
T2 120-131 Phenotype denotes Lung cancer HP:0100526
T3 276-287 Phenotype denotes lung cancer HP:0100526
T4 353-359 Phenotype denotes cancer HP:0002664
T5 514-525 Phenotype denotes lung cancer HP:0100526
T6 665-684 Phenotype denotes lung adenocarcinoma HP:0030078
T7 706-717 Phenotype denotes lung cancer HP:0100526
T8 719-741 Phenotype denotes small-cell lung cancer HP:0030357
T9 743-747 Phenotype denotes SCLC HP:0030357
T10 998-1024 Phenotype denotes non-small-cell lung cancer HP:0030358
T11 1026-1031 Phenotype denotes NSCLC HP:0030358
T12 1192-1203 Phenotype denotes lung cancer HP:0100526
T13 1273-1277 Phenotype denotes SCLC HP:0030357
T14 1316-1321 Phenotype denotes NSCLC HP:0030358
T15 1451-1462 Phenotype denotes lung cancer HP:0100526

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 1248-1252 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 107-118 Disease denotes lung cancer MONDO:0005138|MONDO:0008903
T3 120-131 Disease denotes Lung cancer MONDO:0005138|MONDO:0008903
T5 151-161 Disease denotes malignancy MONDO:0004992
T6 276-287 Disease denotes lung cancer MONDO:0005138|MONDO:0008903
T8 353-359 Disease denotes cancer MONDO:0004992
T9 514-525 Disease denotes lung cancer MONDO:0005138|MONDO:0008903
T11 665-684 Disease denotes lung adenocarcinoma MONDO:0005061
T12 686-689 Disease denotes ADC MONDO:0004970
T13 692-717 Disease denotes squamous cell lung cancer MONDO:0005097
T14 719-741 Disease denotes small-cell lung cancer MONDO:0008433
T15 743-747 Disease denotes SCLC MONDO:0008433
T16 760-778 Disease denotes pulmonary diseases MONDO:0005275
T17 998-1024 Disease denotes non-small-cell lung cancer MONDO:0005233
T18 1026-1031 Disease denotes NSCLC MONDO:0005233
T19 1045-1063 Disease denotes pulmonary diseases MONDO:0005275
T20 1144-1147 Disease denotes ADC MONDO:0004970
T21 1192-1203 Disease denotes lung cancer MONDO:0005138|MONDO:0008903
T23 1273-1277 Disease denotes SCLC MONDO:0008433
T24 1316-1321 Disease denotes NSCLC MONDO:0005233
T25 1451-1462 Disease denotes lung cancer MONDO:0005138|MONDO:0008903

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 651-659 Organism denotes patients 9606

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-119 Sentence denotes Differentially expressed glycosylated patterns of α-1-antitrypsin as serum biomarkers for the diagnosis of lung cancer.
T2 120-172 Sentence denotes Lung cancer is the most common malignancy worldwide.
T3 173-298 Sentence denotes Thus, there is a critical need for diagnostic biomarkers with adequate sensitivity and specificity for lung cancer detection.
T4 299-433 Sentence denotes Glycans in glycoproteins are significantly altered in cancer, and may serve as a tool for identifying potential diagnostic biomarkers.
T5 434-555 Sentence denotes Recent studies have reported changes in α-1-antitrypsin (A1AT) glycosylation in lung cancer serum, tissue and cell lines.
T6 556-779 Sentence denotes In this study, a lectin microarray was used to detect glycosylation changes in serum A1AT from patients with lung adenocarcinoma (ADC), squamous cell lung cancer, small-cell lung cancer (SCLC) and benign pulmonary diseases.
T7 780-945 Sentence denotes Differentially expressed glycosylated patterns of A1AT were identified by lectin arrays and were confirmed by lectin-based enzyme-linked immunosorbent assay (ELISA).
T8 946-1336 Sentence denotes We found that galactosylated A1AT could distinguish non-small-cell lung cancer (NSCLC) from benign pulmonary diseases (AUC = 0.834); fucosylated A1AT showed exceptional capability in distinguishing ADC from benign diseases (AUC = 0.919) or other lung cancer subtypes (AUC = 0.844), and A1AT containing poly-LacNAc could detect SCLC from benign diseases (AUC = 0.905) or NSCLC (AUC = 0.707).
T9 1337-1463 Sentence denotes The present study indicates that glycosylated patterns of A1AT may serve as potential biomarkers for detection of lung cancer.
T10 1464-1567 Sentence denotes Further studies in larger sample sizes are necessary to validate the clinical utility of these markers.

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 1253-1259 Glycan denotes LacNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G66213AR

Lectin-Jamboree-Sentence

Id Subject Object Predicate Lexical cue
T1 0-119 Sentence denotes Differentially expressed glycosylated patterns of α-1-antitrypsin as serum biomarkers for the diagnosis of lung cancer.
T2 120-172 Sentence denotes Lung cancer is the most common malignancy worldwide.
T3 173-298 Sentence denotes Thus, there is a critical need for diagnostic biomarkers with adequate sensitivity and specificity for lung cancer detection.
T4 299-433 Sentence denotes Glycans in glycoproteins are significantly altered in cancer, and may serve as a tool for identifying potential diagnostic biomarkers.
T5 434-555 Sentence denotes Recent studies have reported changes in α-1-antitrypsin (A1AT) glycosylation in lung cancer serum, tissue and cell lines.
T6 556-779 Sentence denotes In this study, a lectin microarray was used to detect glycosylation changes in serum A1AT from patients with lung adenocarcinoma (ADC), squamous cell lung cancer, small-cell lung cancer (SCLC) and benign pulmonary diseases.
T7 780-945 Sentence denotes Differentially expressed glycosylated patterns of A1AT were identified by lectin arrays and were confirmed by lectin-based enzyme-linked immunosorbent assay (ELISA).
T8 946-1336 Sentence denotes We found that galactosylated A1AT could distinguish non-small-cell lung cancer (NSCLC) from benign pulmonary diseases (AUC = 0.834); fucosylated A1AT showed exceptional capability in distinguishing ADC from benign diseases (AUC = 0.919) or other lung cancer subtypes (AUC = 0.844), and A1AT containing poly-LacNAc could detect SCLC from benign diseases (AUC = 0.905) or NSCLC (AUC = 0.707).
T9 1337-1463 Sentence denotes The present study indicates that glycosylated patterns of A1AT may serve as potential biomarkers for detection of lung cancer.
T10 1464-1567 Sentence denotes Further studies in larger sample sizes are necessary to validate the clinical utility of these markers.

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 107-111 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 120-124 Body_part denotes Lung http://purl.obolibrary.org/obo/UBERON_0002048
T3 276-280 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T4 514-518 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T5 533-539 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T6 665-669 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T7 706-710 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T8 730-734 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T9 1013-1017 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T10 1192-1196 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T11 1451-1455 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 69-74 Body_part denotes serum FMA:63083
T2 107-111 Body_part denotes lung FMA:7195
T3 120-124 Body_part denotes Lung FMA:7195
T4 276-280 Body_part denotes lung FMA:7195
T5 514-518 Body_part denotes lung FMA:7195
T6 526-531 Body_part denotes serum FMA:63083
T7 533-539 Body_part denotes tissue FMA:9637
T8 635-640 Body_part denotes serum FMA:63083
T9 665-669 Body_part denotes lung FMA:7195
T10 706-710 Body_part denotes lung FMA:7195
T11 730-734 Body_part denotes lung FMA:7195
T12 1013-1017 Body_part denotes lung FMA:7195
T13 1192-1196 Body_part denotes lung FMA:7195
T14 1451-1455 Body_part denotes lung FMA:7195

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 107-111 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T2 120-124 Body_part denotes Lung http://purl.obolibrary.org/obo/MAT_0000135
T3 276-280 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T4 514-518 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T5 665-669 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T6 706-710 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T7 730-734 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T8 1013-1017 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T9 1192-1196 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T10 1451-1455 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 107-111 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 120-124 Body_part denotes Lung http://purl.obolibrary.org/obo/UBERON_0002048
T3 276-280 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T4 514-518 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T5 533-539 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T6 665-669 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T7 706-710 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T8 730-734 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T9 1013-1017 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T10 1192-1196 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T11 1451-1455 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 1248-1252 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775