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Goldhamster2_Cellosaurus

Id Subject Object Predicate Lexical cue
T1 221-222 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T2 303-304 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T3 408-409 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T4 462-463 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T5 579-580 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T6 803-804 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T7 820-821 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T8 856-858 CVCL_8754|Cancer_cell_line|Homo sapiens denotes an
T9 856-858 CVCL_H241|Cancer_cell_line|Homo sapiens denotes an
T10 999-1000 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T11 1726-1728 CVCL_5M23|Cancer_cell_line|Mesocricetus auratus denotes We
T12 1743-1744 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T13 1821-1823 CVCL_8754|Cancer_cell_line|Homo sapiens denotes an
T14 1821-1823 CVCL_H241|Cancer_cell_line|Homo sapiens denotes an

GoldHamster

Id Subject Object Predicate Lexical cue
T1 19-29 2294143 denotes Drosophila
T2 19-29 504603 denotes Drosophila
T3 19-29 2294139 denotes Drosophila
T4 19-29 2294145 denotes Drosophila
T5 19-29 2294141 denotes Drosophila
T6 19-29 2294142 denotes Drosophila
T7 19-29 2294144 denotes Drosophila
T8 19-29 2294140 denotes Drosophila
T9 19-29 D004330 denotes Drosophila
T10 19-29 2080301 denotes Drosophila
T11 36-42 UBERON:0000473 denotes testis
T12 54-58 UBERON:0003101 denotes male
T13 54-58 CHEBI:30780 denotes male
T14 69-74 D003560 denotes cysts
T15 69-74 D003560 denotes cysts
T16 135-150 GO:0007283 denotes spermatogenesis
T27 169-192 D004331 denotes Drosophila melanogaster
T28 169-192 7227 denotes Drosophila melanogaster
T29 194-198 UBERON:0003101 denotes male
T30 194-198 CHEBI:30780 denotes male
T31 199-209 UBERON:3010292 denotes germ cells
T32 257-266 UBERON:0004529 denotes processes
T33 305-314 CL:0000034 denotes stem cell
T34 354-361 GO:0051321 denotes meiosis
T35 389-399 UBERON:3010292 denotes germ cells
T37 515-524 GO:0000785 denotes chromatin
T36 515-524 D002843 denotes chromatin
T39 529-536 PR:000041244 denotes histone
T38 529-536 D006657 denotes histone
T40 529-536 CHEBI:15358 denotes histone
T41 540-549 P0C230 denotes protamine
T43 540-549 P15340 denotes protamine
T44 540-549 P29629 denotes protamine
T45 540-549 Q91185 denotes protamine
T46 540-549 P14402 denotes protamine
T47 540-549 P17502 denotes protamine
T48 540-549 Q9PS27 denotes protamine
T50 540-549 P69014 denotes protamine
T49 540-549 CHEBI:16757 denotes protamine
T42 540-549 8826 denotes protamine
T55 581-588 SO:0000104 denotes protein
T54 581-588 PR:000000001 denotes protein
T51 581-588 GO:0003675 denotes protein
T52 581-588 CHEBI:36080 denotes protein
T53 581-588 CHEBI:11122 denotes protein
T56 605-620 GO:0007283 denotes spermatogenesis
T58 627-638 SO:0001148 denotes mutagenesis
T57 627-638 GO:0006280 denotes mutagenesis
T59 692-701 P02301 denotes embryonic
T60 692-701 PR:000029532 denotes embryonic
T63 703-706 SO:0002045 denotes pre
T62 703-706 PR:Q8LLD0 denotes pre
T64 703-706 UBERON:0001782 denotes pre
T61 703-706 GO:0003904 denotes pre
T69 744-751 SO:0000104 denotes protein
T68 744-751 PR:000000001 denotes protein
T65 744-751 GO:0003675 denotes protein
T66 744-751 CHEBI:36080 denotes protein
T67 744-751 CHEBI:11122 denotes protein
T73 822-829 PR:000000001 denotes protein
T71 822-829 CHEBI:36080 denotes protein
T72 822-829 CHEBI:11122 denotes protein
T74 822-829 SO:0000104 denotes protein
T70 822-829 GO:0003675 denotes protein
T75 959-967 UBERON:0000468 denotes organism
T86 968-991 D004331 denotes Drosophila melanogaster
T87 968-991 7227 denotes Drosophila melanogaster
T88 1032-1038 UBERON:0000473 denotes testes
T89 1048-1053 D003560 denotes cysts
T90 1048-1053 D003560 denotes cysts
T91 1057-1067 UBERON:3010292 denotes germ cells
T92 1089-1094 D011679 denotes pupae
T93 1089-1094 UBERON:0003143 denotes pupae
T94 1207-1217 UBERON:3010292 denotes germ cells
T95 1221-1227 UBERON:0000473 denotes testes
T96 1245-1250 D003560 denotes cysts
T97 1245-1250 D003560 denotes cysts
T98 1280-1286 UBERON:0000473 denotes testes
T99 1291-1301 UBERON:3010292 denotes germ cells
T100 1344-1354 CHEBI:35222 denotes inhibitors
T101 1391-1400 SO:0001185 denotes enzymatic
T102 1418-1433 GO:0007283 denotes spermatogenesis
T103 1534-1540 UBERON:0000473 denotes testes
T104 1555-1560 D003560 denotes cysts
T105 1555-1560 D003560 denotes cysts
T106 1602-1608 UBERON:0000473 denotes testes
T107 1687-1693 UBERON:0000473 denotes testes
T108 1708-1713 D003560 denotes cysts
T109 1708-1713 D003560 denotes cysts
T110 1789-1804 GO:0007283 denotes spermatogenesis
T112 1844-1851 PR:000041244 denotes histone
T111 1844-1851 D006657 denotes histone
T113 1844-1851 CHEBI:15358 denotes histone
T114 1855-1864 P0C230 denotes protamine
T116 1855-1864 P15340 denotes protamine
T117 1855-1864 P29629 denotes protamine
T118 1855-1864 Q91185 denotes protamine
T119 1855-1864 P14402 denotes protamine
T120 1855-1864 P17502 denotes protamine
T121 1855-1864 Q9PS27 denotes protamine
T123 1855-1864 P69014 denotes protamine
T115 1855-1864 8826 denotes protamine
T122 1855-1864 CHEBI:16757 denotes protamine
T128 1882-1907 P9WKY4 denotes histone acetyltransferase
T129 1882-1907 P9WKY5 denotes histone acetyltransferase
T130 1882-1917 CHEBI:76395 denotes histone acetyltransferase inhibitor
T134 1918-1932 C088115 denotes anacardic acid
T135 1918-1932 CHEBI:2696 denotes anacardic acid
T136 1918-1932 C088115 denotes anacardic acid
T139 2033-2036 PR:Q8LLD0 denotes pre
T141 2033-2036 UBERON:0001782 denotes pre
T140 2033-2036 SO:0002045 denotes pre
T138 2033-2036 GO:0003904 denotes pre
T142 2055-2070 GO:0007283 denotes spermatogenesis

PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T1 128-267 DRI_Background denotes During spermatogenesis in mammals and in Drosophila melanogaster, male germ cells develop in a series of essential developmental processes.
T2 268-362 DRI_Approach denotes This includes differentiation from a stem cell population, mitotic amplification, and meiosis.
T3 363-514 DRI_Background denotes In addition, post-meiotic germ cells undergo a dramatic morphological reshaping process as well as a global epigenetic reconfiguration of the germ line
T4 550-557 DRI_Background denotes switch.
T5 558-772 DRI_Background denotes Studying the role of a protein in post-meiotic spermatogenesis using mutagenesis or other genetic tools is often impeded by essential embryonic, pre-meiotic, or meiotic functions of the protein under investigation.
T6 773-948 DRI_Challenge denotes The post-meiotic phenotype of a mutant of such a protein could be obscured through an earlier developmental block, or the interpretation of the phenotype could be complicated.
T7 949-1141 DRI_Challenge denotes The model organism Drosophila melanogaster offers a bypass to this problem: intact testes and even cysts of germ cells dissected from early pupae are able to develop ex vivo in culture medium.
T8 1142-1251 DRI_Background denotes Making use of such cultures allows microscopic imaging of living germ cells in testes and of germ-line cysts.
T9 1252-1465 DRI_Background denotes Importantly, the cultivated testes and germ cells also become accessible to pharmacological inhibitors, thereby permitting manipulation of enzymatic functions during spermatogenesis, including post-meiotic stages.
T10 1466-1561 DRI_Outcome denotes The protocol presented describes how to dissect and cultivate pupal testes and germ-line cysts.
T11 1562-1725 DRI_Background denotes Information on the development of pupal testes and culture conditions are provided alongside microscope imaging data of live testes and germ-line cysts in culture.
T12 1726-1933 DRI_Background denotes We also describe a pharmacological assay to study post-meiotic spermatogenesis, exemplified by an assay targeting the histone-to-protamine switch using the histone acetyltransferase inhibitor anacardic acid.
T13 1934-2071 DRI_Background denotes In principle, this cultivation method could be adapted to address many other research questions in pre- and post-meiotic spermatogenesis.