PubMed:25147369 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/25147369","sourcedb":"PubMed","sourceid":"25147369","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/25147369","text":"Prognostic parameters in uveal melanoma and their association with BAP1 expression.\nAIM: To determine whether BAP1 gene and protein expression associates with different prognostic parameters in uveal melanoma and whether BAP1 expression correctly identifies patients as being at risk for metastases, following enucleation of the primary tumour.\nMETHODS: Thirty cases of uveal melanoma obtained by enucleation between 1999 and 2004 were analysed for a variety of prognostic markers, including histological characteristics, chromosome aberrations obtained by fluorescence in situ hybridisation (FISH) and single nucleotide polymorphism (SNP) analysis and gene expression profiling. These parameters were compared with BAP1 gene expression and BAP1 immunostaining.\nRESULTS: The presence of monosomy of chromosome 3 as identified by the different chromosome 3 tests showed significantly increased HRs (FISH on isolated nuclei cut-off 30%: HR 11.6, p=0.002; SNP analysis: HR 20.3, p=0.004) for death due to metastasis. The gene expression profile class 2, based on the 15-gene expression profile, similarly provided a significantly increased HR for a poor outcome (HR 8.5, p=0.005). Lower BAP1 gene expression and negative BAP1 immunostaining (50% of 28 tumours were immunonegative) were both associated with these markers for prognostication: FISH cut-off 30% monosomy 3 (BAP1 gene expression: p=0.037; BAP1 immunostaining: p=0.001), SNP-monosomy 3 (BAP1 gene expression: p=0.008; BAP1 immunostaining: p=0.002) and class 2 profile (BAP1 gene expression: p\u003c0.001; BAP1 immunostaining: p=0.001) and were themselves associated with an increased risk of death due to metastasis (BAP1 gene expression dichotomised: HR 8.7, p=0.006; BAP1 immunostaining: HR 4.0, p=0.010).\nCONCLUSIONS: Loss of BAP1 expression associated well with all of the methods currently used for prognostication and was itself predictive of death due to metastasis in uveal melanoma after enucleation, thereby emphasising the importance of further research on the role of BAP1 in uveal melanoma.","tracks":[{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":67,"end":71},"obj":"gene:8314"},{"id":"T1","span":{"begin":25,"end":39},"obj":"disease:C0220633"},{"id":"T2","span":{"begin":67,"end":71},"obj":"gene:9223"},{"id":"T3","span":{"begin":25,"end":39},"obj":"disease:C0220633"},{"id":"T4","span":{"begin":67,"end":71},"obj":"gene:6045"},{"id":"T5","span":{"begin":25,"end":39},"obj":"disease:C0220633"},{"id":"T6","span":{"begin":110,"end":114},"obj":"gene:8314"},{"id":"T7","span":{"begin":194,"end":208},"obj":"disease:C0220633"},{"id":"T8","span":{"begin":110,"end":114},"obj":"gene:9223"},{"id":"T9","span":{"begin":194,"end":208},"obj":"disease:C0220633"},{"id":"T10","span":{"begin":110,"end":114},"obj":"gene:6045"},{"id":"T11","span":{"begin":194,"end":208},"obj":"disease:C0220633"},{"id":"T12","span":{"begin":110,"end":114},"obj":"gene:8314"},{"id":"T13","span":{"begin":288,"end":298},"obj":"disease:C0027627"},{"id":"T14","span":{"begin":110,"end":114},"obj":"gene:8314"},{"id":"T15","span":{"begin":288,"end":298},"obj":"disease:C2939419"},{"id":"T16","span":{"begin":110,"end":114},"obj":"gene:9223"},{"id":"T17","span":{"begin":288,"end":298},"obj":"disease:C0027627"},{"id":"T18","span":{"begin":110,"end":114},"obj":"gene:9223"},{"id":"T19","span":{"begin":288,"end":298},"obj":"disease:C2939419"},{"id":"T20","span":{"begin":110,"end":114},"obj":"gene:6045"},{"id":"T21","span":{"begin":288,"end":298},"obj":"disease:C0027627"},{"id":"T22","span":{"begin":110,"end":114},"obj":"gene:6045"},{"id":"T23","span":{"begin":288,"end":298},"obj":"disease:C2939419"},{"id":"T24","span":{"begin":221,"end":225},"obj":"gene:8314"},{"id":"T25","span":{"begin":194,"end":208},"obj":"disease:C0220633"},{"id":"T26","span":{"begin":221,"end":225},"obj":"gene:9223"},{"id":"T27","span":{"begin":194,"end":208},"obj":"disease:C0220633"},{"id":"T28","span":{"begin":221,"end":225},"obj":"gene:6045"},{"id":"T29","span":{"begin":194,"end":208},"obj":"disease:C0220633"},{"id":"T30","span":{"begin":221,"end":225},"obj":"gene:8314"},{"id":"T31","span":{"begin":288,"end":298},"obj":"disease:C0027627"},{"id":"T32","span":{"begin":221,"end":225},"obj":"gene:8314"},{"id":"T33","span":{"begin":288,"end":298},"obj":"disease:C2939419"},{"id":"T34","span":{"begin":221,"end":225},"obj":"gene:9223"},{"id":"T35","span":{"begin":288,"end":298},"obj":"disease:C0027627"},{"id":"T36","span":{"begin":221,"end":225},"obj":"gene:9223"},{"id":"T37","span":{"begin":288,"end":298},"obj":"disease:C2939419"},{"id":"T38","span":{"begin":221,"end":225},"obj":"gene:6045"},{"id":"T39","span":{"begin":288,"end":298},"obj":"disease:C0027627"},{"id":"T40","span":{"begin":221,"end":225},"obj":"gene:6045"},{"id":"T41","span":{"begin":288,"end":298},"obj":"disease:C2939419"},{"id":"T42","span":{"begin":1184,"end":1188},"obj":"gene:8314"},{"id":"T43","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T44","span":{"begin":1184,"end":1188},"obj":"gene:9223"},{"id":"T45","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T46","span":{"begin":1184,"end":1188},"obj":"gene:6045"},{"id":"T47","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T48","span":{"begin":1184,"end":1188},"obj":"gene:8314"},{"id":"T49","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T50","span":{"begin":1184,"end":1188},"obj":"gene:9223"},{"id":"T51","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T52","span":{"begin":1184,"end":1188},"obj":"gene:6045"},{"id":"T53","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T54","span":{"begin":1184,"end":1188},"obj":"gene:8314"},{"id":"T55","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T56","span":{"begin":1184,"end":1188},"obj":"gene:8314"},{"id":"T57","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T58","span":{"begin":1184,"end":1188},"obj":"gene:9223"},{"id":"T59","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T60","span":{"begin":1184,"end":1188},"obj":"gene:9223"},{"id":"T61","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T62","span":{"begin":1184,"end":1188},"obj":"gene:6045"},{"id":"T63","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T64","span":{"begin":1184,"end":1188},"obj":"gene:6045"},{"id":"T65","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T66","span":{"begin":1218,"end":1222},"obj":"gene:8314"},{"id":"T67","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T68","span":{"begin":1218,"end":1222},"obj":"gene:9223"},{"id":"T69","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T70","span":{"begin":1218,"end":1222},"obj":"gene:6045"},{"id":"T71","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T72","span":{"begin":1218,"end":1222},"obj":"gene:8314"},{"id":"T73","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T74","span":{"begin":1218,"end":1222},"obj":"gene:9223"},{"id":"T75","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T76","span":{"begin":1218,"end":1222},"obj":"gene:6045"},{"id":"T77","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T78","span":{"begin":1218,"end":1222},"obj":"gene:8314"},{"id":"T79","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T80","span":{"begin":1218,"end":1222},"obj":"gene:8314"},{"id":"T81","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T82","span":{"begin":1218,"end":1222},"obj":"gene:9223"},{"id":"T83","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T84","span":{"begin":1218,"end":1222},"obj":"gene:9223"},{"id":"T85","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T86","span":{"begin":1218,"end":1222},"obj":"gene:6045"},{"id":"T87","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T88","span":{"begin":1218,"end":1222},"obj":"gene:6045"},{"id":"T89","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T90","span":{"begin":1368,"end":1372},"obj":"gene:8314"},{"id":"T91","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T92","span":{"begin":1368,"end":1372},"obj":"gene:9223"},{"id":"T93","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T94","span":{"begin":1368,"end":1372},"obj":"gene:6045"},{"id":"T95","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T96","span":{"begin":1368,"end":1372},"obj":"gene:8314"},{"id":"T97","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T98","span":{"begin":1368,"end":1372},"obj":"gene:8314"},{"id":"T99","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T100","span":{"begin":1368,"end":1372},"obj":"gene:9223"},{"id":"T101","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T102","span":{"begin":1368,"end":1372},"obj":"gene:9223"},{"id":"T103","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T104","span":{"begin":1368,"end":1372},"obj":"gene:6045"},{"id":"T105","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T106","span":{"begin":1368,"end":1372},"obj":"gene:6045"},{"id":"T107","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T108","span":{"begin":1399,"end":1403},"obj":"gene:8314"},{"id":"T109","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T110","span":{"begin":1399,"end":1403},"obj":"gene:9223"},{"id":"T111","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T112","span":{"begin":1399,"end":1403},"obj":"gene:6045"},{"id":"T113","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T114","span":{"begin":1399,"end":1403},"obj":"gene:8314"},{"id":"T115","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T116","span":{"begin":1399,"end":1403},"obj":"gene:9223"},{"id":"T117","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T118","span":{"begin":1399,"end":1403},"obj":"gene:6045"},{"id":"T119","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T120","span":{"begin":1399,"end":1403},"obj":"gene:8314"},{"id":"T121","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T122","span":{"begin":1399,"end":1403},"obj":"gene:8314"},{"id":"T123","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T124","span":{"begin":1399,"end":1403},"obj":"gene:9223"},{"id":"T125","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T126","span":{"begin":1399,"end":1403},"obj":"gene:9223"},{"id":"T127","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T128","span":{"begin":1399,"end":1403},"obj":"gene:6045"},{"id":"T129","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T130","span":{"begin":1399,"end":1403},"obj":"gene:6045"},{"id":"T131","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T132","span":{"begin":1446,"end":1450},"obj":"gene:8314"},{"id":"T133","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T134","span":{"begin":1446,"end":1450},"obj":"gene:9223"},{"id":"T135","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T136","span":{"begin":1446,"end":1450},"obj":"gene:6045"},{"id":"T137","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T138","span":{"begin":1446,"end":1450},"obj":"gene:8314"},{"id":"T139","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T140","span":{"begin":1446,"end":1450},"obj":"gene:8314"},{"id":"T141","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T142","span":{"begin":1446,"end":1450},"obj":"gene:9223"},{"id":"T143","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T144","span":{"begin":1446,"end":1450},"obj":"gene:9223"},{"id":"T145","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T146","span":{"begin":1446,"end":1450},"obj":"gene:6045"},{"id":"T147","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T148","span":{"begin":1446,"end":1450},"obj":"gene:6045"},{"id":"T149","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T150","span":{"begin":1477,"end":1481},"obj":"gene:8314"},{"id":"T151","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T152","span":{"begin":1477,"end":1481},"obj":"gene:9223"},{"id":"T153","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T154","span":{"begin":1477,"end":1481},"obj":"gene:6045"},{"id":"T155","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T156","span":{"begin":1477,"end":1481},"obj":"gene:8314"},{"id":"T157","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T158","span":{"begin":1477,"end":1481},"obj":"gene:8314"},{"id":"T159","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T160","span":{"begin":1477,"end":1481},"obj":"gene:9223"},{"id":"T161","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T162","span":{"begin":1477,"end":1481},"obj":"gene:9223"},{"id":"T163","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T164","span":{"begin":1477,"end":1481},"obj":"gene:6045"},{"id":"T165","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T166","span":{"begin":1477,"end":1481},"obj":"gene:6045"},{"id":"T167","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T168","span":{"begin":1528,"end":1532},"obj":"gene:8314"},{"id":"T169","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T170","span":{"begin":1528,"end":1532},"obj":"gene:9223"},{"id":"T171","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T172","span":{"begin":1528,"end":1532},"obj":"gene:6045"},{"id":"T173","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T174","span":{"begin":1528,"end":1532},"obj":"gene:8314"},{"id":"T175","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T176","span":{"begin":1528,"end":1532},"obj":"gene:8314"},{"id":"T177","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T178","span":{"begin":1528,"end":1532},"obj":"gene:9223"},{"id":"T179","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T180","span":{"begin":1528,"end":1532},"obj":"gene:9223"},{"id":"T181","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T182","span":{"begin":1528,"end":1532},"obj":"gene:6045"},{"id":"T183","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T184","span":{"begin":1528,"end":1532},"obj":"gene:6045"},{"id":"T185","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T186","span":{"begin":1559,"end":1563},"obj":"gene:8314"},{"id":"T187","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T188","span":{"begin":1559,"end":1563},"obj":"gene:9223"},{"id":"T189","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T190","span":{"begin":1559,"end":1563},"obj":"gene:6045"},{"id":"T191","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T192","span":{"begin":1559,"end":1563},"obj":"gene:8314"},{"id":"T193","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T194","span":{"begin":1559,"end":1563},"obj":"gene:8314"},{"id":"T195","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T196","span":{"begin":1559,"end":1563},"obj":"gene:9223"},{"id":"T197","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T198","span":{"begin":1559,"end":1563},"obj":"gene:9223"},{"id":"T199","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T200","span":{"begin":1559,"end":1563},"obj":"gene:6045"},{"id":"T201","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T202","span":{"begin":1559,"end":1563},"obj":"gene:6045"},{"id":"T203","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T204","span":{"begin":1671,"end":1675},"obj":"gene:8314"},{"id":"T205","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T206","span":{"begin":1671,"end":1675},"obj":"gene:9223"},{"id":"T207","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T208","span":{"begin":1671,"end":1675},"obj":"gene:6045"},{"id":"T209","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T210","span":{"begin":1671,"end":1675},"obj":"gene:8314"},{"id":"T211","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T212","span":{"begin":1671,"end":1675},"obj":"gene:8314"},{"id":"T213","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T214","span":{"begin":1671,"end":1675},"obj":"gene:9223"},{"id":"T215","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T216","span":{"begin":1671,"end":1675},"obj":"gene:9223"},{"id":"T217","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T218","span":{"begin":1671,"end":1675},"obj":"gene:6045"},{"id":"T219","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T220","span":{"begin":1671,"end":1675},"obj":"gene:6045"},{"id":"T221","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T222","span":{"begin":1723,"end":1727},"obj":"gene:8314"},{"id":"T223","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T224","span":{"begin":1723,"end":1727},"obj":"gene:9223"},{"id":"T225","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T226","span":{"begin":1723,"end":1727},"obj":"gene:6045"},{"id":"T227","span":{"begin":1356,"end":1364},"obj":"disease:C0026499"},{"id":"T228","span":{"begin":1723,"end":1727},"obj":"gene:8314"},{"id":"T229","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T230","span":{"begin":1723,"end":1727},"obj":"gene:9223"},{"id":"T231","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T232","span":{"begin":1723,"end":1727},"obj":"gene:6045"},{"id":"T233","span":{"begin":1434,"end":1442},"obj":"disease:C0026499"},{"id":"T234","span":{"begin":1723,"end":1727},"obj":"gene:8314"},{"id":"T235","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T236","span":{"begin":1723,"end":1727},"obj":"gene:8314"},{"id":"T237","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T238","span":{"begin":1723,"end":1727},"obj":"gene:9223"},{"id":"T239","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T240","span":{"begin":1723,"end":1727},"obj":"gene:9223"},{"id":"T241","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T242","span":{"begin":1723,"end":1727},"obj":"gene:6045"},{"id":"T243","span":{"begin":1659,"end":1669},"obj":"disease:C0027627"},{"id":"T244","span":{"begin":1723,"end":1727},"obj":"gene:6045"},{"id":"T245","span":{"begin":1659,"end":1669},"obj":"disease:C2939420"},{"id":"T246","span":{"begin":1783,"end":1787},"obj":"gene:8314"},{"id":"T247","span":{"begin":1916,"end":1926},"obj":"disease:C0027627"},{"id":"T248","span":{"begin":1783,"end":1787},"obj":"gene:8314"},{"id":"T249","span":{"begin":1916,"end":1926},"obj":"disease:C2939420"},{"id":"T250","span":{"begin":1783,"end":1787},"obj":"gene:9223"},{"id":"T251","span":{"begin":1916,"end":1926},"obj":"disease:C0027627"},{"id":"T252","span":{"begin":1783,"end":1787},"obj":"gene:9223"},{"id":"T253","span":{"begin":1916,"end":1926},"obj":"disease:C2939420"},{"id":"T254","span":{"begin":1783,"end":1787},"obj":"gene:6045"},{"id":"T255","span":{"begin":1916,"end":1926},"obj":"disease:C0027627"},{"id":"T256","span":{"begin":1783,"end":1787},"obj":"gene:6045"},{"id":"T257","span":{"begin":1916,"end":1926},"obj":"disease:C2939420"},{"id":"T258","span":{"begin":1783,"end":1787},"obj":"gene:8314"},{"id":"T259","span":{"begin":1930,"end":1944},"obj":"disease:C0220633"},{"id":"T260","span":{"begin":1783,"end":1787},"obj":"gene:9223"},{"id":"T261","span":{"begin":1930,"end":1944},"obj":"disease:C0220633"},{"id":"T262","span":{"begin":1783,"end":1787},"obj":"gene:6045"},{"id":"T263","span":{"begin":1930,"end":1944},"obj":"disease:C0220633"},{"id":"T264","span":{"begin":1783,"end":1787},"obj":"gene:8314"},{"id":"T265","span":{"begin":2042,"end":2056},"obj":"disease:C0220633"},{"id":"T266","span":{"begin":1783,"end":1787},"obj":"gene:9223"},{"id":"T267","span":{"begin":2042,"end":2056},"obj":"disease:C0220633"},{"id":"T268","span":{"begin":1783,"end":1787},"obj":"gene:6045"},{"id":"T269","span":{"begin":2042,"end":2056},"obj":"disease:C0220633"},{"id":"T270","span":{"begin":2034,"end":2038},"obj":"gene:8314"},{"id":"T271","span":{"begin":1916,"end":1926},"obj":"disease:C0027627"},{"id":"T272","span":{"begin":2034,"end":2038},"obj":"gene:8314"},{"id":"T273","span":{"begin":1916,"end":1926},"obj":"disease:C2939420"},{"id":"T274","span":{"begin":2034,"end":2038},"obj":"gene:9223"},{"id":"T275","span":{"begin":1916,"end":1926},"obj":"disease:C0027627"},{"id":"T276","span":{"begin":2034,"end":2038},"obj":"gene:9223"},{"id":"T277","span":{"begin":1916,"end":1926},"obj":"disease:C2939420"},{"id":"T278","span":{"begin":2034,"end":2038},"obj":"gene:6045"},{"id":"T279","span":{"begin":1916,"end":1926},"obj":"disease:C0027627"},{"id":"T280","span":{"begin":2034,"end":2038},"obj":"gene:6045"},{"id":"T281","span":{"begin":1916,"end":1926},"obj":"disease:C2939420"},{"id":"T282","span":{"begin":2034,"end":2038},"obj":"gene:8314"},{"id":"T283","span":{"begin":1930,"end":1944},"obj":"disease:C0220633"},{"id":"T284","span":{"begin":2034,"end":2038},"obj":"gene:9223"},{"id":"T285","span":{"begin":1930,"end":1944},"obj":"disease:C0220633"},{"id":"T286","span":{"begin":2034,"end":2038},"obj":"gene:6045"},{"id":"T287","span":{"begin":1930,"end":1944},"obj":"disease:C0220633"},{"id":"T288","span":{"begin":2034,"end":2038},"obj":"gene:8314"},{"id":"T289","span":{"begin":2042,"end":2056},"obj":"disease:C0220633"},{"id":"T290","span":{"begin":2034,"end":2038},"obj":"gene:9223"},{"id":"T291","span":{"begin":2042,"end":2056},"obj":"disease:C0220633"},{"id":"T292","span":{"begin":2034,"end":2038},"obj":"gene:6045"},{"id":"T293","span":{"begin":2042,"end":2056},"obj":"disease:C0220633"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"},{"id":"R2","pred":"associated_with","subj":"T2","obj":"T3"},{"id":"R3","pred":"associated_with","subj":"T4","obj":"T5"},{"id":"R4","pred":"associated_with","subj":"T6","obj":"T7"},{"id":"R5","pred":"associated_with","subj":"T8","obj":"T9"},{"id":"R6","pred":"associated_with","subj":"T10","obj":"T11"},{"id":"R7","pred":"associated_with","subj":"T12","obj":"T13"},{"id":"R8","pred":"associated_with","subj":"T14","obj":"T15"},{"id":"R9","pred":"associated_with","subj":"T16","obj":"T17"},{"id":"R10","pred":"associated_with","subj":"T18","obj":"T19"},{"id":"R11","pred":"associated_with","subj":"T20","obj":"T21"},{"id":"R12","pred":"associated_with","subj":"T22","obj":"T23"},{"id":"R13","pred":"associated_with","subj":"T24","obj":"T25"},{"id":"R14","pred":"associated_with","subj":"T26","obj":"T27"},{"id":"R15","pred":"associated_with","subj":"T28","obj":"T29"},{"id":"R16","pred":"associated_with","subj":"T30","obj":"T31"},{"id":"R17","pred":"associated_with","subj":"T32","obj":"T33"},{"id":"R18","pred":"associated_with","subj":"T34","obj":"T35"},{"id":"R19","pred":"associated_with","subj":"T36","obj":"T37"},{"id":"R20","pred":"associated_with","subj":"T38","obj":"T39"},{"id":"R21","pred":"associated_with","subj":"T40","obj":"T41"},{"id":"R22","pred":"associated_with","subj":"T42","obj":"T43"},{"id":"R23","pred":"associated_with","subj":"T44","obj":"T45"},{"id":"R24","pred":"associated_with","subj":"T46","obj":"T47"},{"id":"R25","pred":"associated_with","subj":"T48","obj":"T49"},{"id":"R26","pred":"associated_with","subj":"T50","obj":"T51"},{"id":"R27","pred":"associated_with","subj":"T52","obj":"T53"},{"id":"R28","pred":"associated_with","subj":"T54","obj":"T55"},{"id":"R29","pred":"associated_with","subj":"T56","obj":"T57"},{"id":"R30","pred":"associated_with","subj":"T58","obj":"T59"},{"id":"R31","pred":"associated_with","subj":"T60","obj":"T61"},{"id":"R32","pred":"associated_with","subj":"T62","obj":"T63"},{"id":"R33","pred":"associated_with","subj":"T64","obj":"T65"},{"id":"R34","pred":"associated_with","subj":"T66","obj":"T67"},{"id":"R35","pred":"associated_with","subj":"T68","obj":"T69"},{"id":"R36","pred":"associated_with","subj":"T70","obj":"T71"},{"id":"R37","pred":"associated_with","subj":"T72","obj":"T73"},{"id":"R38","pred":"associated_with","subj":"T74","obj":"T75"},{"id":"R39","pred":"associated_with","subj":"T76","obj":"T77"},{"id":"R40","pred":"associated_with","subj":"T78","obj":"T79"},{"id":"R41","pred":"associated_with","subj":"T80","obj":"T81"},{"id":"R42","pred":"associated_with","subj":"T82","obj":"T83"},{"id":"R43","pred":"associated_with","subj":"T84","obj":"T85"},{"id":"R44","pred":"associated_with","subj":"T86","obj":"T87"},{"id":"R45","pred":"associated_with","subj":"T88","obj":"T89"},{"id":"R46","pred":"associated_with","subj":"T90","obj":"T91"},{"id":"R47","pred":"associated_with","subj":"T92","obj":"T93"},{"id":"R48","pred":"associated_with","subj":"T94","obj":"T95"},{"id":"R49","pred":"associated_with","subj":"T96","obj":"T97"},{"id":"R50","pred":"associated_with","subj":"T98","obj":"T99"},{"id":"R51","pred":"associated_with","subj":"T100","obj":"T101"},{"id":"R52","pred":"associated_with","subj":"T102","obj":"T103"},{"id":"R53","pred":"associated_with","subj":"T104","obj":"T105"},{"id":"R54","pred":"associated_with","subj":"T106","obj":"T107"},{"id":"R55","pred":"associated_with","subj":"T108","obj":"T109"},{"id":"R56","pred":"associated_with","subj":"T110","obj":"T111"},{"id":"R57","pred":"associated_with","subj":"T112","obj":"T113"},{"id":"R58","pred":"associated_with","subj":"T114","obj":"T115"},{"id":"R59","pred":"associated_with","subj":"T116","obj":"T117"},{"id":"R60","pred":"associated_with","subj":"T118","obj":"T119"},{"id":"R61","pred":"associated_with","subj":"T120","obj":"T121"},{"id":"R62","pred":"associated_with","subj":"T122","obj":"T123"},{"id":"R63","pred":"associated_with","subj":"T124","obj":"T125"},{"id":"R64","pred":"associated_with","subj":"T126","obj":"T127"},{"id":"R65","pred":"associated_with","subj":"T128","obj":"T129"},{"id":"R66","pred":"associated_with","subj":"T130","obj":"T131"},{"id":"R67","pred":"associated_with","subj":"T132","obj":"T133"},{"id":"R68","pred":"associated_with","subj":"T134","obj":"T135"},{"id":"R69","pred":"associated_with","subj":"T136","obj":"T137"},{"id":"R70","pred":"associated_with","subj":"T138","obj":"T139"},{"id":"R71","pred":"associated_with","subj":"T140","obj":"T141"},{"id":"R72","pred":"associated_with","subj":"T142","obj":"T143"},{"id":"R73","pred":"associated_with","subj":"T144","obj":"T145"},{"id":"R74","pred":"associated_with","subj":"T146","obj":"T147"},{"id":"R75","pred":"associated_with","subj":"T148","obj":"T149"},{"id":"R76","pred":"associated_with","subj":"T150","obj":"T151"},{"id":"R77","pred":"associated_with","subj":"T152","obj":"T153"},{"id":"R78","pred":"associated_with","subj":"T154","obj":"T155"},{"id":"R79","pred":"associated_with","subj":"T156","obj":"T157"},{"id":"R80","pred":"associated_with","subj":"T158","obj":"T159"},{"id":"R81","pred":"associated_with","subj":"T160","obj":"T161"},{"id":"R82","pred":"associated_with","subj":"T162","obj":"T163"},{"id":"R83","pred":"associated_with","subj":"T164","obj":"T165"},{"id":"R84","pred":"associated_with","subj":"T166","obj":"T167"},{"id":"R85","pred":"associated_with","subj":"T168","obj":"T169"},{"id":"R86","pred":"associated_with","subj":"T170","obj":"T171"},{"id":"R87","pred":"associated_with","subj":"T172","obj":"T173"},{"id":"R88","pred":"associated_with","subj":"T174","obj":"T175"},{"id":"R89","pred":"associated_with","subj":"T176","obj":"T177"},{"id":"R90","pred":"associated_with","subj":"T178","obj":"T179"},{"id":"R91","pred":"associated_with","subj":"T180","obj":"T181"},{"id":"R92","pred":"associated_with","subj":"T182","obj":"T183"},{"id":"R93","pred":"associated_with","subj":"T184","obj":"T185"},{"id":"R94","pred":"associated_with","subj":"T186","obj":"T187"},{"id":"R95","pred":"associated_with","subj":"T188","obj":"T189"},{"id":"R96","pred":"associated_with","subj":"T190","obj":"T191"},{"id":"R97","pred":"associated_with","subj":"T192","obj":"T193"},{"id":"R98","pred":"associated_with","subj":"T194","obj":"T195"},{"id":"R99","pred":"associated_with","subj":"T196","obj":"T197"},{"id":"R100","pred":"associated_with","subj":"T198","obj":"T199"},{"id":"R101","pred":"associated_with","subj":"T200","obj":"T201"},{"id":"R102","pred":"associated_with","subj":"T202","obj":"T203"},{"id":"R103","pred":"associated_with","subj":"T204","obj":"T205"},{"id":"R104","pred":"associated_with","subj":"T206","obj":"T207"},{"id":"R105","pred":"associated_with","subj":"T208","obj":"T209"},{"id":"R106","pred":"associated_with","subj":"T210","obj":"T211"},{"id":"R107","pred":"associated_with","subj":"T212","obj":"T213"},{"id":"R108","pred":"associated_with","subj":"T214","obj":"T215"},{"id":"R109","pred":"associated_with","subj":"T216","obj":"T217"},{"id":"R110","pred":"associated_with","subj":"T218","obj":"T219"},{"id":"R111","pred":"associated_with","subj":"T220","obj":"T221"},{"id":"R112","pred":"associated_with","subj":"T222","obj":"T223"},{"id":"R113","pred":"associated_with","subj":"T224","obj":"T225"},{"id":"R114","pred":"associated_with","subj":"T226","obj":"T227"},{"id":"R115","pred":"associated_with","subj":"T228","obj":"T229"},{"id":"R116","pred":"associated_with","subj":"T230","obj":"T231"},{"id":"R117","pred":"associated_with","subj":"T232","obj":"T233"},{"id":"R118","pred":"associated_with","subj":"T234","obj":"T235"},{"id":"R119","pred":"associated_with","subj":"T236","obj":"T237"},{"id":"R120","pred":"associated_with","subj":"T238","obj":"T239"},{"id":"R121","pred":"associated_with","subj":"T240","obj":"T241"},{"id":"R122","pred":"associated_with","subj":"T242","obj":"T243"},{"id":"R123","pred":"associated_with","subj":"T244","obj":"T245"},{"id":"R124","pred":"associated_with","subj":"T246","obj":"T247"},{"id":"R125","pred":"associated_with","subj":"T248","obj":"T249"},{"id":"R126","pred":"associated_with","subj":"T250","obj":"T251"},{"id":"R127","pred":"associated_with","subj":"T252","obj":"T253"},{"id":"R128","pred":"associated_with","subj":"T254","obj":"T255"},{"id":"R129","pred":"associated_with","subj":"T256","obj":"T257"},{"id":"R130","pred":"associated_with","subj":"T258","obj":"T259"},{"id":"R131","pred":"associated_with","subj":"T260","obj":"T261"},{"id":"R132","pred":"associated_with","subj":"T262","obj":"T263"},{"id":"R133","pred":"associated_with","subj":"T264","obj":"T265"},{"id":"R134","pred":"associated_with","subj":"T266","obj":"T267"},{"id":"R135","pred":"associated_with","subj":"T268","obj":"T269"},{"id":"R136","pred":"associated_with","subj":"T270","obj":"T271"},{"id":"R137","pred":"associated_with","subj":"T272","obj":"T273"},{"id":"R138","pred":"associated_with","subj":"T274","obj":"T275"},{"id":"R139","pred":"associated_with","subj":"T276","obj":"T277"},{"id":"R140","pred":"associated_with","subj":"T278","obj":"T279"},{"id":"R141","pred":"associated_with","subj":"T280","obj":"T281"},{"id":"R142","pred":"associated_with","subj":"T282","obj":"T283"},{"id":"R143","pred":"associated_with","subj":"T284","obj":"T285"},{"id":"R144","pred":"associated_with","subj":"T286","obj":"T287"},{"id":"R145","pred":"associated_with","subj":"T288","obj":"T289"},{"id":"R146","pred":"associated_with","subj":"T290","obj":"T291"},{"id":"R147","pred":"associated_with","subj":"T292","obj":"T293"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"attributes":[{"subj":"T0","pred":"source","obj":"DisGeNET"},{"subj":"T1","pred":"source","obj":"DisGeNET"},{"subj":"T2","pred":"source","obj":"DisGeNET"},{"subj":"T3","pred":"source","obj":"DisGeNET"},{"subj":"T4","pred":"source","obj":"DisGeNET"},{"subj":"T5","pred":"source","obj":"DisGeNET"},{"subj":"T6","pred":"source","obj":"DisGeNET"},{"subj":"T7","pred":"source","obj":"DisGeNET"},{"subj":"T8","pred":"source","obj":"DisGeNET"},{"subj":"T9","pred":"source","obj":"DisGeNET"},{"subj":"T10","pred":"source","obj":"DisGeNET"},{"subj":"T11","pred":"source","obj":"DisGeNET"},{"subj":"T12","pred":"source","obj":"DisGeNET"},{"subj":"T13","pred":"source","obj":"DisGeNET"},{"subj":"T14","pred":"source","obj":"DisGeNET"},{"subj":"T15","pred":"source","obj":"DisGeNET"},{"subj":"T16","pred":"source","obj":"DisGeNET"},{"subj":"T17","pred":"source","obj":"DisGeNET"},{"subj":"T18","pred":"source","obj":"DisGeNET"},{"subj":"T19","pred":"source","obj":"DisGeNET"},{"subj":"T20","pred":"source","obj":"DisGeNET"},{"subj":"T21","pred":"source","obj":"DisGeNET"},{"subj":"T22","pred":"source","obj":"DisGeNET"},{"subj":"T23","pred":"source","obj":"DisGeNET"},{"subj":"T24","pred":"source","obj":"DisGeNET"},{"subj":"T25","pred":"source","obj":"DisGeNET"},{"subj":"T26","pred":"source","obj":"DisGeNET"},{"subj":"T27","pred":"source","obj":"DisGeNET"},{"subj":"T28","pred":"source","obj":"DisGeNET"},{"subj":"T29","pred":"source","obj":"DisGeNET"},{"subj":"T30","pred":"source","obj":"DisGeNET"},{"subj":"T31","pred":"source","obj":"DisGeNET"},{"subj":"T32","pred":"source","obj":"DisGeNET"},{"subj":"T33","pred":"source","obj":"DisGeNET"},{"subj":"T34","pred":"source","obj":"DisGeNET"},{"subj":"T35","pred":"source","obj":"DisGeNET"},{"subj":"T36","pred":"source","obj":"DisGeNET"},{"subj":"T37","pred":"source","obj":"DisGeNET"},{"subj":"T38","pred":"source","obj":"DisGeNET"},{"subj":"T39","pred":"source","obj":"DisGeNET"},{"subj":"T40","pred":"source","obj":"DisGeNET"},{"subj":"T41","pred":"source","obj":"DisGeNET"},{"subj":"T42","pred":"source","obj":"DisGeNET"},{"subj":"T43","pred":"source","obj":"DisGeNET"},{"subj":"T44","pred":"source","obj":"DisGeNET"},{"subj":"T45","pred":"source","obj":"DisGeNET"},{"subj":"T46","pred":"source","obj":"DisGeNET"},{"subj":"T47","pred":"source","obj":"DisGeNET"},{"subj":"T48","pred":"source","obj":"DisGeNET"},{"subj":"T49","pred":"source","obj":"DisGeNET"},{"subj":"T50","pred":"source","obj":"DisGeNET"},{"subj":"T51","pred":"source","obj":"DisGeNET"},{"subj":"T52","pred":"source","obj":"DisGeNET"},{"subj":"T53","pred":"source","obj":"DisGeNET"},{"subj":"T54","pred":"source","obj":"DisGeNET"},{"subj":"T55","pred":"source","obj":"DisGeNET"},{"subj":"T56","pred":"source","obj":"DisGeNET"},{"subj":"T57","pred":"source","obj":"DisGeNET"},{"subj":"T58","pred":"source","obj":"DisGeNET"},{"subj":"T59","pred":"source","obj":"DisGeNET"},{"subj":"T60","pred":"source","obj":"DisGeNET"},{"subj":"T61","pred":"source","obj":"DisGeNET"},{"subj":"T62","pred":"source","obj":"DisGeNET"},{"subj":"T63","pred":"source","obj":"DisGeNET"},{"subj":"T64","pred":"source","obj":"DisGeNET"},{"subj":"T65","pred":"source","obj":"DisGeNET"},{"subj":"T66","pred":"source","obj":"DisGeNET"},{"subj":"T67","pred":"source","obj":"DisGeNET"},{"subj":"T68","pred":"source","obj":"DisGeNET"},{"subj":"T69","pred":"source","obj":"DisGeNET"},{"subj":"T70","pred":"source","obj":"DisGeNET"},{"subj":"T71","pred":"source","obj":"DisGeNET"},{"subj":"T72","pred":"source","obj":"DisGeNET"},{"subj":"T73","pred":"source","obj":"DisGeNET"},{"subj":"T74","pred":"source","obj":"DisGeNET"},{"subj":"T75","pred":"source","obj":"DisGeNET"},{"subj":"T76","pred":"source","obj":"DisGeNET"},{"subj":"T77","pred":"source","obj":"DisGeNET"},{"subj":"T78","pred":"source","obj":"DisGeNET"},{"subj":"T79","pred":"source","obj":"DisGeNET"},{"subj":"T80","pred":"source","obj":"DisGeNET"},{"subj":"T81","pred":"source","obj":"DisGeNET"},{"subj":"T82","pred":"source","obj":"DisGeNET"},{"subj":"T83","pred":"source","obj":"DisGeNET"},{"subj":"T84","pred":"source","obj":"DisGeNET"},{"subj":"T85","pred":"source","obj":"DisGeNET"},{"subj":"T86","pred":"source","obj":"DisGeNET"},{"subj":"T87","pred":"source","obj":"DisGeNET"},{"subj":"T88","pred":"source","obj":"DisGeNET"},{"subj":"T89","pred":"source","obj":"DisGeNET"},{"subj":"T90","pred":"source","obj":"DisGeNET"},{"subj":"T91","pred":"source","obj":"DisGeNET"},{"subj":"T92","pred":"source","obj":"DisGeNET"},{"subj":"T93","pred":"source","obj":"DisGeNET"},{"subj":"T94","pred":"source","obj":"DisGeNET"},{"subj":"T95","pred":"source","obj":"DisGeNET"},{"subj":"T96","pred":"source","obj":"DisGeNET"},{"subj":"T97","pred":"source","obj":"DisGeNET"},{"subj":"T98","pred":"source","obj":"DisGeNET"},{"subj":"T99","pred":"source","obj":"DisGeNET"},{"subj":"T100","pred":"source","obj":"DisGeNET"},{"subj":"T101","pred":"source","obj":"DisGeNET"},{"subj":"T102","pred":"source","obj":"DisGeNET"},{"subj":"T103","pred":"source","obj":"DisGeNET"},{"subj":"T104","pred":"source","obj":"DisGeNET"},{"subj":"T105","pred":"source","obj":"DisGeNET"},{"subj":"T106","pred":"source","obj":"DisGeNET"},{"subj":"T107","pred":"source","obj":"DisGeNET"},{"subj":"T108","pred":"source","obj":"DisGeNET"},{"subj":"T109","pred":"source","obj":"DisGeNET"},{"subj":"T110","pred":"source","obj":"DisGeNET"},{"subj":"T111","pred":"source","obj":"DisGeNET"},{"subj":"T112","pred":"source","obj":"DisGeNET"},{"subj":"T113","pred":"source","obj":"DisGeNET"},{"subj":"T114","pred":"source","obj":"DisGeNET"},{"subj":"T115","pred":"source","obj":"DisGeNET"},{"subj":"T116","pred":"source","obj":"DisGeNET"},{"subj":"T117","pred":"source","obj":"DisGeNET"},{"subj":"T118","pred":"source","obj":"DisGeNET"},{"subj":"T119","pred":"source","obj":"DisGeNET"},{"subj":"T120","pred":"source","obj":"DisGeNET"},{"subj":"T121","pred":"source","obj":"DisGeNET"},{"subj":"T122","pred":"source","obj":"DisGeNET"},{"subj":"T123","pred":"source","obj":"DisGeNET"},{"subj":"T124","pred":"source","obj":"DisGeNET"},{"subj":"T125","pred":"source","obj":"DisGeNET"},{"subj":"T126","pred":"source","obj":"DisGeNET"},{"subj":"T127","pred":"source","obj":"DisGeNET"},{"subj":"T128","pred":"source","obj":"DisGeNET"},{"subj":"T129","pred":"source","obj":"DisGeNET"},{"subj":"T130","pred":"source","obj":"DisGeNET"},{"subj":"T131","pred":"source","obj":"DisGeNET"},{"subj":"T132","pred":"source","obj":"DisGeNET"},{"subj":"T133","pred":"source","obj":"DisGeNET"},{"subj":"T134","pred":"source","obj":"DisGeNET"},{"subj":"T135","pred":"source","obj":"DisGeNET"},{"subj":"T136","pred":"source","obj":"DisGeNET"},{"subj":"T137","pred":"source","obj":"DisGeNET"},{"subj":"T138","pred":"source","obj":"DisGeNET"},{"subj":"T139","pred":"source","obj":"DisGeNET"},{"subj":"T140","pred":"source","obj":"DisGeNET"},{"subj":"T141","pred":"source","obj":"DisGeNET"},{"subj":"T142","pred":"source","obj":"DisGeNET"},{"subj":"T143","pred":"source","obj":"DisGeNET"},{"subj":"T144","pred":"source","obj":"DisGeNET"},{"subj":"T145","pred":"source","obj":"DisGeNET"},{"subj":"T146","pred":"source","obj":"DisGeNET"},{"subj":"T147","pred":"source","obj":"DisGeNET"},{"subj":"T148","pred":"source","obj":"DisGeNET"},{"subj":"T149","pred":"source","obj":"DisGeNET"},{"subj":"T150","pred":"source","obj":"DisGeNET"},{"subj":"T151","pred":"source","obj":"DisGeNET"},{"subj":"T152","pred":"source","obj":"DisGeNET"},{"subj":"T153","pred":"source","obj":"DisGeNET"},{"subj":"T154","pred":"source","obj":"DisGeNET"},{"subj":"T155","pred":"source","obj":"DisGeNET"},{"subj":"T156","pred":"source","obj":"DisGeNET"},{"subj":"T157","pred":"source","obj":"DisGeNET"},{"subj":"T158","pred":"source","obj":"DisGeNET"},{"subj":"T159","pred":"source","obj":"DisGeNET"},{"subj":"T160","pred":"source","obj":"DisGeNET"},{"subj":"T161","pred":"source","obj":"DisGeNET"},{"subj":"T162","pred":"source","obj":"DisGeNET"},{"subj":"T163","pred":"source","obj":"DisGeNET"},{"subj":"T164","pred":"source","obj":"DisGeNET"},{"subj":"T165","pred":"source","obj":"DisGeNET"},{"subj":"T166","pred":"source","obj":"DisGeNET"},{"subj":"T167","pred":"source","obj":"DisGeNET"},{"subj":"T168","pred":"source","obj":"DisGeNET"},{"subj":"T169","pred":"source","obj":"DisGeNET"},{"subj":"T170","pred":"source","obj":"DisGeNET"},{"subj":"T171","pred":"source","obj":"DisGeNET"},{"subj":"T172","pred":"source","obj":"DisGeNET"},{"subj":"T173","pred":"source","obj":"DisGeNET"},{"subj":"T174","pred":"source","obj":"DisGeNET"},{"subj":"T175","pred":"source","obj":"DisGeNET"},{"subj":"T176","pred":"source","obj":"DisGeNET"},{"subj":"T177","pred":"source","obj":"DisGeNET"},{"subj":"T178","pred":"source","obj":"DisGeNET"},{"subj":"T179","pred":"source","obj":"DisGeNET"},{"subj":"T180","pred":"source","obj":"DisGeNET"},{"subj":"T181","pred":"source","obj":"DisGeNET"},{"subj":"T182","pred":"source","obj":"DisGeNET"},{"subj":"T183","pred":"source","obj":"DisGeNET"},{"subj":"T184","pred":"source","obj":"DisGeNET"},{"subj":"T185","pred":"source","obj":"DisGeNET"},{"subj":"T186","pred":"source","obj":"DisGeNET"},{"subj":"T187","pred":"source","obj":"DisGeNET"},{"subj":"T188","pred":"source","obj":"DisGeNET"},{"subj":"T189","pred":"source","obj":"DisGeNET"},{"subj":"T190","pred":"source","obj":"DisGeNET"},{"subj":"T191","pred":"source","obj":"DisGeNET"},{"subj":"T192","pred":"source","obj":"DisGeNET"},{"subj":"T193","pred":"source","obj":"DisGeNET"},{"subj":"T194","pred":"source","obj":"DisGeNET"},{"subj":"T195","pred":"source","obj":"DisGeNET"},{"subj":"T196","pred":"source","obj":"DisGeNET"},{"subj":"T197","pred":"source","obj":"DisGeNET"},{"subj":"T198","pred":"source","obj":"DisGeNET"},{"subj":"T199","pred":"source","obj":"DisGeNET"},{"subj":"T200","pred":"source","obj":"DisGeNET"},{"subj":"T201","pred":"source","obj":"DisGeNET"},{"subj":"T202","pred":"source","obj":"DisGeNET"},{"subj":"T203","pred":"source","obj":"DisGeNET"},{"subj":"T204","pred":"source","obj":"DisGeNET"},{"subj":"T205","pred":"source","obj":"DisGeNET"},{"subj":"T206","pred":"source","obj":"DisGeNET"},{"subj":"T207","pred":"source","obj":"DisGeNET"},{"subj":"T208","pred":"source","obj":"DisGeNET"},{"subj":"T209","pred":"source","obj":"DisGeNET"},{"subj":"T210","pred":"source","obj":"DisGeNET"},{"subj":"T211","pred":"source","obj":"DisGeNET"},{"subj":"T212","pred":"source","obj":"DisGeNET"},{"subj":"T213","pred":"source","obj":"DisGeNET"},{"subj":"T214","pred":"source","obj":"DisGeNET"},{"subj":"T215","pred":"source","obj":"DisGeNET"},{"subj":"T216","pred":"source","obj":"DisGeNET"},{"subj":"T217","pred":"source","obj":"DisGeNET"},{"subj":"T218","pred":"source","obj":"DisGeNET"},{"subj":"T219","pred":"source","obj":"DisGeNET"},{"subj":"T220","pred":"source","obj":"DisGeNET"},{"subj":"T221","pred":"source","obj":"DisGeNET"},{"subj":"T222","pred":"source","obj":"DisGeNET"},{"subj":"T223","pred":"source","obj":"DisGeNET"},{"subj":"T224","pred":"source","obj":"DisGeNET"},{"subj":"T225","pred":"source","obj":"DisGeNET"},{"subj":"T226","pred":"source","obj":"DisGeNET"},{"subj":"T227","pred":"source","obj":"DisGeNET"},{"subj":"T228","pred":"source","obj":"DisGeNET"},{"subj":"T229","pred":"source","obj":"DisGeNET"},{"subj":"T230","pred":"source","obj":"DisGeNET"},{"subj":"T231","pred":"source","obj":"DisGeNET"},{"subj":"T232","pred":"source","obj":"DisGeNET"},{"subj":"T233","pred":"source","obj":"DisGeNET"},{"subj":"T234","pred":"source","obj":"DisGeNET"},{"subj":"T235","pred":"source","obj":"DisGeNET"},{"subj":"T236","pred":"source","obj":"DisGeNET"},{"subj":"T237","pred":"source","obj":"DisGeNET"},{"subj":"T238","pred":"source","obj":"DisGeNET"},{"subj":"T239","pred":"source","obj":"DisGeNET"},{"subj":"T240","pred":"source","obj":"DisGeNET"},{"subj":"T241","pred":"source","obj":"DisGeNET"},{"subj":"T242","pred":"source","obj":"DisGeNET"},{"subj":"T243","pred":"source","obj":"DisGeNET"},{"subj":"T244","pred":"source","obj":"DisGeNET"},{"subj":"T245","pred":"source","obj":"DisGeNET"},{"subj":"T246","pred":"source","obj":"DisGeNET"},{"subj":"T247","pred":"source","obj":"DisGeNET"},{"subj":"T248","pred":"source","obj":"DisGeNET"},{"subj":"T249","pred":"source","obj":"DisGeNET"},{"subj":"T250","pred":"source","obj":"DisGeNET"},{"subj":"T251","pred":"source","obj":"DisGeNET"},{"subj":"T252","pred":"source","obj":"DisGeNET"},{"subj":"T253","pred":"source","obj":"DisGeNET"},{"subj":"T254","pred":"source","obj":"DisGeNET"},{"subj":"T255","pred":"source","obj":"DisGeNET"},{"subj":"T256","pred":"source","obj":"DisGeNET"},{"subj":"T257","pred":"source","obj":"DisGeNET"},{"subj":"T258","pred":"source","obj":"DisGeNET"},{"subj":"T259","pred":"source","obj":"DisGeNET"},{"subj":"T260","pred":"source","obj":"DisGeNET"},{"subj":"T261","pred":"source","obj":"DisGeNET"},{"subj":"T262","pred":"source","obj":"DisGeNET"},{"subj":"T263","pred":"source","obj":"DisGeNET"},{"subj":"T264","pred":"source","obj":"DisGeNET"},{"subj":"T265","pred":"source","obj":"DisGeNET"},{"subj":"T266","pred":"source","obj":"DisGeNET"},{"subj":"T267","pred":"source","obj":"DisGeNET"},{"subj":"T268","pred":"source","obj":"DisGeNET"},{"subj":"T269","pred":"source","obj":"DisGeNET"},{"subj":"T270","pred":"source","obj":"DisGeNET"},{"subj":"T271","pred":"source","obj":"DisGeNET"},{"subj":"T272","pred":"source","obj":"DisGeNET"},{"subj":"T273","pred":"source","obj":"DisGeNET"},{"subj":"T274","pred":"source","obj":"DisGeNET"},{"subj":"T275","pred":"source","obj":"DisGeNET"},{"subj":"T276","pred":"source","obj":"DisGeNET"},{"subj":"T277","pred":"source","obj":"DisGeNET"},{"subj":"T278","pred":"source","obj":"DisGeNET"},{"subj":"T279","pred":"source","obj":"DisGeNET"},{"subj":"T280","pred":"source","obj":"DisGeNET"},{"subj":"T281","pred":"source","obj":"DisGeNET"},{"subj":"T282","pred":"source","obj":"DisGeNET"},{"subj":"T283","pred":"source","obj":"DisGeNET"},{"subj":"T284","pred":"source","obj":"DisGeNET"},{"subj":"T285","pred":"source","obj":"DisGeNET"},{"subj":"T286","pred":"source","obj":"DisGeNET"},{"subj":"T287","pred":"source","obj":"DisGeNET"},{"subj":"T288","pred":"source","obj":"DisGeNET"},{"subj":"T289","pred":"source","obj":"DisGeNET"},{"subj":"T290","pred":"source","obj":"DisGeNET"},{"subj":"T291","pred":"source","obj":"DisGeNET"},{"subj":"T292","pred":"source","obj":"DisGeNET"},{"subj":"T293","pred":"source","obj":"DisGeNET"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":194,"end":208},"obj":"HP_0007716"},{"id":"T2","span":{"begin":200,"end":208},"obj":"HP_0002861"},{"id":"T3","span":{"begin":337,"end":343},"obj":"HP_0002664"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"},{"subj":"T3","pred":"source","obj":"PubmedHPO"}]},{"project":"DisGeNET5_gene_disease","denotations":[{"id":"25147369-0#67#71#gene8314","span":{"begin":716,"end":720},"obj":"gene8314"},{"id":"25147369-0#25#39#diseaseC0220633","span":{"begin":194,"end":208},"obj":"diseaseC0220633"},{"id":"25147369-6#6#10#gene8314","span":{"begin":1184,"end":1188},"obj":"gene8314"},{"id":"25147369-6#40#44#gene8314","span":{"begin":1218,"end":1222},"obj":"gene8314"},{"id":"25147369-6#190#194#gene8314","span":{"begin":1368,"end":1372},"obj":"gene8314"},{"id":"25147369-6#221#225#gene8314","span":{"begin":1399,"end":1403},"obj":"gene8314"},{"id":"25147369-6#268#272#gene8314","span":{"begin":1446,"end":1450},"obj":"gene8314"},{"id":"25147369-6#299#303#gene8314","span":{"begin":1477,"end":1481},"obj":"gene8314"},{"id":"25147369-6#350#354#gene8314","span":{"begin":1528,"end":1532},"obj":"gene8314"},{"id":"25147369-6#381#385#gene8314","span":{"begin":1559,"end":1563},"obj":"gene8314"},{"id":"25147369-6#493#497#gene8314","span":{"begin":1671,"end":1675},"obj":"gene8314"},{"id":"25147369-6#545#549#gene8314","span":{"begin":1723,"end":1727},"obj":"gene8314"},{"id":"25147369-6#178#186#diseaseC0026499","span":{"begin":1356,"end":1364},"obj":"diseaseC0026499"},{"id":"25147369-6#256#264#diseaseC0026499","span":{"begin":1434,"end":1442},"obj":"diseaseC0026499"},{"id":"25147369-6#178#186#diseaseC0026499","span":{"begin":1356,"end":1364},"obj":"diseaseC0026499"},{"id":"25147369-6#256#264#diseaseC0026499","span":{"begin":1434,"end":1442},"obj":"diseaseC0026499"},{"id":"25147369-6#178#186#diseaseC0026499","span":{"begin":1356,"end":1364},"obj":"diseaseC0026499"},{"id":"25147369-6#256#264#diseaseC0026499","span":{"begin":1434,"end":1442},"obj":"diseaseC0026499"},{"id":"25147369-6#178#186#diseaseC0026499","span":{"begin":1356,"end":1364},"obj":"diseaseC0026499"},{"id":"25147369-6#256#264#diseaseC0026499","span":{"begin":1434,"end":1442},"obj":"diseaseC0026499"},{"id":"25147369-6#178#186#diseaseC0026499","span":{"begin":1356,"end":1364},"obj":"diseaseC0026499"},{"id":"25147369-6#256#264#diseaseC0026499","span":{"begin":1434,"end":1442},"obj":"diseaseC0026499"},{"id":"25147369-6#178#186#diseaseC0026499","span":{"begin":1356,"end":1364},"obj":"diseaseC0026499"},{"id":"25147369-6#256#264#diseaseC0026499","span":{"begin":1434,"end":1442},"obj":"diseaseC0026499"},{"id":"25147369-7#8#12#gene8314","span":{"begin":1783,"end":1787},"obj":"gene8314"},{"id":"25147369-7#259#263#gene8314","span":{"begin":2034,"end":2038},"obj":"gene8314"},{"id":"25147369-7#141#151#diseaseC0027627","span":{"begin":1916,"end":1926},"obj":"diseaseC0027627"}],"relations":[{"id":"67#71#gene831425#39#diseaseC0220633","pred":"associated_with","subj":"25147369-0#67#71#gene8314","obj":"25147369-0#25#39#diseaseC0220633"},{"id":"6#10#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"6#10#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"6#10#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"6#10#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"6#10#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"6#10#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"6#10#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"6#10#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"6#10#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"6#10#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"6#10#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"6#10#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#6#10#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"40#44#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"40#44#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"40#44#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"40#44#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"40#44#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"40#44#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"40#44#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"40#44#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"40#44#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"40#44#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"40#44#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"40#44#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#40#44#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"190#194#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"190#194#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"190#194#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"190#194#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"190#194#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"190#194#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"190#194#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"190#194#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"190#194#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"190#194#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"190#194#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"190#194#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#190#194#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"221#225#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"221#225#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"221#225#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"221#225#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"221#225#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"221#225#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"221#225#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"221#225#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"221#225#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"221#225#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"221#225#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"221#225#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#221#225#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"268#272#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"268#272#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"268#272#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"268#272#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"268#272#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"268#272#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"268#272#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"268#272#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"268#272#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"268#272#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"268#272#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"268#272#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#268#272#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"299#303#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"299#303#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"299#303#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"299#303#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"299#303#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"299#303#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"299#303#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"299#303#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"299#303#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"299#303#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"299#303#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"299#303#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#299#303#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"350#354#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"350#354#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"350#354#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"350#354#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"350#354#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"350#354#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"350#354#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"350#354#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"350#354#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"350#354#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"350#354#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"350#354#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#350#354#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"381#385#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"381#385#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"381#385#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"381#385#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"381#385#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"381#385#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"381#385#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"381#385#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"381#385#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"381#385#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"381#385#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"381#385#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#381#385#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"493#497#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"493#497#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"493#497#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"493#497#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"493#497#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"493#497#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"493#497#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"493#497#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"493#497#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"493#497#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"493#497#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"493#497#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#493#497#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"545#549#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"545#549#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"545#549#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"545#549#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"545#549#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"545#549#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"545#549#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"545#549#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"545#549#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"545#549#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"545#549#gene8314178#186#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#178#186#diseaseC0026499"},{"id":"545#549#gene8314256#264#diseaseC0026499","pred":"associated_with","subj":"25147369-6#545#549#gene8314","obj":"25147369-6#256#264#diseaseC0026499"},{"id":"8#12#gene8314141#151#diseaseC0027627","pred":"associated_with","subj":"25147369-7#8#12#gene8314","obj":"25147369-7#141#151#diseaseC0027627"},{"id":"259#263#gene8314141#151#diseaseC0027627","pred":"associated_with","subj":"25147369-7#259#263#gene8314","obj":"25147369-7#141#151#diseaseC0027627"}],"attributes":[{"subj":"25147369-0#67#71#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-0#25#39#diseaseC0220633","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#6#10#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#40#44#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#190#194#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#221#225#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#268#272#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#299#303#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#350#354#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#381#385#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#493#497#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#545#549#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#178#186#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#256#264#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#178#186#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#256#264#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#178#186#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#256#264#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#178#186#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#256#264#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#178#186#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#256#264#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#178#186#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-6#256#264#diseaseC0026499","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-7#8#12#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-7#259#263#gene8314","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"25147369-7#141#151#diseaseC0027627","pred":"source","obj":"DisGeNET5_gene_disease"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"DisGeNET","color":"#93ece1","default":true},{"id":"PubmedHPO","color":"#ecc793"},{"id":"DisGeNET5_gene_disease","color":"#ad93ec"}]}]}}