PubMed:25037694 / 629-1830
Annnotations
PubMed_Structured_Abstracts
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3 | 0-1201 | RESULTS | denotes | Testosterone-treated aged rabbits had longer corrected QT interval, higher low frequency/high frequency, greater left ventricle (LV) mass but lower LA total emptying fraction and LV ejection fraction than control rabbits. In tissue preparations, the spontaneous rate was faster for testosterone-treated PVs than for control PVs. Angiotensin II concentration-dependently increased the amplitude of delayed afterdepolarizations (DADs) in testosterone-treated PVs but only did so at the highest angiotensin II concentration (100 nM) in control PVs. Isoproterenol increased the incidence of early afterdepolarizations (EADs) and DADs in testosterone-treated PVs but not in control PVs. Testosterone-treated PVs had more H2O2-induced burst firing and EADs than control PVs. Testosterone-treated LAs had more isoproterenol-induced DADs and spontaneous activity than did control LAs. However, acetylcholine infusion and rapid atrial pacing (10-20 Hz) induced AF in control LAs but not in testosterone-treated LAs. In addition, as compared with control LAs, testosterone-treated LAs expressed more androgen receptor, β1-adrenergic receptor, and Cav 1.2 and less G protein-coupled receptor kinase-2 and Kv 4.2. |
Goldhamster2_Cellosaurus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5 | 846-854 | CVCL_C410|Hybridoma|Mus musculus | denotes | activity |
T6 | 937-939 | CVCL_J923|Hybridoma|Mus musculus | denotes | 20 |
T7 | 1137-1140 | CVCL_LM72|Cancer_cell_line|Homo sapiens | denotes | Cav |
T8 | 1141-1144 | CVCL_0C53|Cancer_cell_line|Homo sapiens | denotes | 1.2 |
GoldHamster
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T39 | 0-12 | 10379 | denotes | Testosterone |
T36 | 0-12 | D013739 | denotes | Testosterone |
T37 | 0-12 | CHEBI:17347 | denotes | Testosterone |
T38 | 0-12 | D013739 | denotes | Testosterone |
T40 | 26-33 | D011817 | denotes | rabbits |
T41 | 26-33 | 9986 | denotes | rabbits |
T42 | 113-127 | UBERON:0002084 | denotes | left ventricle |
T44 | 213-220 | D011817 | denotes | rabbits |
T45 | 213-220 | 9986 | denotes | rabbits |
T46 | 225-231 | UBERON:0000479 | denotes | tissue |
T50 | 282-294 | 10379 | denotes | testosterone |
T47 | 282-294 | D013739 | denotes | testosterone |
T48 | 282-294 | CHEBI:17347 | denotes | testosterone |
T49 | 282-294 | D013739 | denotes | testosterone |
T51 | 303-306 | PR:000002067 | denotes | PVs |
T52 | 303-306 | PR:P15151 | denotes | PVs |
T53 | 303-306 | PR:P32507 | denotes | PVs |
T54 | 303-306 | PR:000002069 | denotes | PVs |
T55 | 324-327 | PR:000002067 | denotes | PVs |
T56 | 324-327 | PR:P15151 | denotes | PVs |
T57 | 324-327 | PR:P32507 | denotes | PVs |
T58 | 324-327 | PR:000002069 | denotes | PVs |
T68 | 329-343 | PR:000036009 | denotes | Angiotensin II |
T70 | 329-343 | 1999003 | denotes | Angiotensin II |
T64 | 329-343 | D000804 | denotes | Angiotensin II |
T65 | 329-343 | CHEBI:2719 | denotes | Angiotensin II |
T66 | 329-343 | D000804 | denotes | Angiotensin II |
T67 | 329-343 | CHEBI:58506 | denotes | Angiotensin II |
T69 | 329-343 | CHEBI:48432 | denotes | Angiotensin II |
T71 | 427-431 | C025953 | denotes | DADs |
T72 | 427-431 | C025953 | denotes | DADs |
T76 | 436-448 | 10379 | denotes | testosterone |
T73 | 436-448 | D013739 | denotes | testosterone |
T74 | 436-448 | CHEBI:17347 | denotes | testosterone |
T75 | 436-448 | D013739 | denotes | testosterone |
T77 | 457-460 | PR:000002067 | denotes | PVs |
T78 | 457-460 | PR:P15151 | denotes | PVs |
T79 | 457-460 | PR:P32507 | denotes | PVs |
T80 | 457-460 | PR:000002069 | denotes | PVs |
T90 | 492-506 | PR:000036009 | denotes | angiotensin II |
T92 | 492-506 | 1999003 | denotes | angiotensin II |
T86 | 492-506 | D000804 | denotes | angiotensin II |
T87 | 492-506 | CHEBI:2719 | denotes | angiotensin II |
T88 | 492-506 | D000804 | denotes | angiotensin II |
T89 | 492-506 | CHEBI:58506 | denotes | angiotensin II |
T91 | 492-506 | CHEBI:48432 | denotes | angiotensin II |
T93 | 541-544 | PR:000002067 | denotes | PVs |
T94 | 541-544 | PR:P15151 | denotes | PVs |
T95 | 541-544 | PR:P32507 | denotes | PVs |
T96 | 541-544 | PR:000002069 | denotes | PVs |
T97 | 546-559 | 6054 | denotes | Isoproterenol |
T98 | 546-559 | D007545 | denotes | Isoproterenol |
T99 | 546-559 | D007545 | denotes | Isoproterenol |
T100 | 546-559 | CHEBI:64317 | denotes | Isoproterenol |
T101 | 546-559 | CHEBI:6257 | denotes | Isoproterenol |
T102 | 625-629 | C025953 | denotes | DADs |
T103 | 625-629 | C025953 | denotes | DADs |
T107 | 633-645 | 10379 | denotes | testosterone |
T104 | 633-645 | D013739 | denotes | testosterone |
T105 | 633-645 | CHEBI:17347 | denotes | testosterone |
T106 | 633-645 | D013739 | denotes | testosterone |
T108 | 654-657 | PR:000002067 | denotes | PVs |
T109 | 654-657 | PR:P15151 | denotes | PVs |
T110 | 654-657 | PR:P32507 | denotes | PVs |
T111 | 654-657 | PR:000002069 | denotes | PVs |
T112 | 677-680 | PR:000002067 | denotes | PVs |
T113 | 677-680 | PR:P15151 | denotes | PVs |
T114 | 677-680 | PR:P32507 | denotes | PVs |
T115 | 677-680 | PR:000002069 | denotes | PVs |
T119 | 682-694 | 10379 | denotes | Testosterone |
T116 | 682-694 | D013739 | denotes | Testosterone |
T117 | 682-694 | CHEBI:17347 | denotes | Testosterone |
T118 | 682-694 | D013739 | denotes | Testosterone |
T120 | 703-706 | PR:000002067 | denotes | PVs |
T121 | 703-706 | PR:P15151 | denotes | PVs |
T122 | 703-706 | PR:P32507 | denotes | PVs |
T123 | 703-706 | PR:000002069 | denotes | PVs |
T126 | 716-720 | CHEBI:16240 | denotes | H2O2 |
T127 | 764-767 | PR:000002067 | denotes | PVs |
T128 | 764-767 | PR:P15151 | denotes | PVs |
T129 | 764-767 | PR:P32507 | denotes | PVs |
T130 | 764-767 | PR:000002069 | denotes | PVs |
T134 | 769-781 | 10379 | denotes | Testosterone |
T131 | 769-781 | D013739 | denotes | Testosterone |
T132 | 769-781 | CHEBI:17347 | denotes | Testosterone |
T133 | 769-781 | D013739 | denotes | Testosterone |
T135 | 790-793 | PR:Q7JQW6 | denotes | LAs |
T136 | 790-793 | PR:Q9ZWC5 | denotes | LAs |
T138 | 790-793 | PR:000009798 | denotes | LAs |
T139 | 790-793 | PR:O43766 | denotes | LAs |
T137 | 790-793 | CHEBI:73525 | denotes | LAs |
T140 | 803-816 | 6054 | denotes | isoproterenol |
T141 | 803-816 | D007545 | denotes | isoproterenol |
T142 | 803-816 | D007545 | denotes | isoproterenol |
T143 | 803-816 | CHEBI:64317 | denotes | isoproterenol |
T144 | 803-816 | CHEBI:6257 | denotes | isoproterenol |
T145 | 825-829 | C025953 | denotes | DADs |
T146 | 825-829 | C025953 | denotes | DADs |
T147 | 872-875 | PR:Q7JQW6 | denotes | LAs |
T148 | 872-875 | PR:Q9ZWC5 | denotes | LAs |
T150 | 872-875 | PR:000009798 | denotes | LAs |
T151 | 872-875 | PR:O43766 | denotes | LAs |
T149 | 872-875 | CHEBI:73525 | denotes | LAs |
T153 | 886-899 | 194 | denotes | acetylcholine |
T152 | 886-899 | D000109 | denotes | acetylcholine |
T154 | 886-899 | CHEBI:15355 | denotes | acetylcholine |
T155 | 886-899 | D000109 | denotes | acetylcholine |
T156 | 966-969 | PR:Q7JQW6 | denotes | LAs |
T157 | 966-969 | PR:Q9ZWC5 | denotes | LAs |
T159 | 966-969 | PR:000009798 | denotes | LAs |
T160 | 966-969 | PR:O43766 | denotes | LAs |
T158 | 966-969 | CHEBI:73525 | denotes | LAs |
T164 | 981-993 | 10379 | denotes | testosterone |
T161 | 981-993 | D013739 | denotes | testosterone |
T162 | 981-993 | CHEBI:17347 | denotes | testosterone |
T163 | 981-993 | D013739 | denotes | testosterone |
T165 | 1002-1005 | PR:Q7JQW6 | denotes | LAs |
T166 | 1002-1005 | PR:Q9ZWC5 | denotes | LAs |
T168 | 1002-1005 | PR:000009798 | denotes | LAs |
T169 | 1002-1005 | PR:O43766 | denotes | LAs |
T167 | 1002-1005 | CHEBI:73525 | denotes | LAs |
T170 | 1045-1048 | PR:Q7JQW6 | denotes | LAs |
T171 | 1045-1048 | PR:Q9ZWC5 | denotes | LAs |
T173 | 1045-1048 | PR:000009798 | denotes | LAs |
T174 | 1045-1048 | PR:O43766 | denotes | LAs |
T172 | 1045-1048 | CHEBI:73525 | denotes | LAs |
T178 | 1050-1062 | 10379 | denotes | testosterone |
T175 | 1050-1062 | D013739 | denotes | testosterone |
T176 | 1050-1062 | CHEBI:17347 | denotes | testosterone |
T177 | 1050-1062 | D013739 | denotes | testosterone |
T179 | 1071-1074 | PR:Q7JQW6 | denotes | LAs |
T180 | 1071-1074 | PR:Q9ZWC5 | denotes | LAs |
T182 | 1071-1074 | PR:000009798 | denotes | LAs |
T183 | 1071-1074 | PR:O43766 | denotes | LAs |
T181 | 1071-1074 | CHEBI:73525 | denotes | LAs |
T185 | 1090-1107 | Q9GKL7 | denotes | androgen receptor |
T186 | 1090-1107 | Q9TT90 | denotes | androgen receptor |
T188 | 1090-1107 | O97775 | denotes | androgen receptor |
T189 | 1090-1107 | O97776 | denotes | androgen receptor |
T190 | 1090-1107 | Q7T1K4 | denotes | androgen receptor |
T191 | 1090-1107 | Q8MIK0 | denotes | androgen receptor |
T192 | 1090-1107 | Q6QT55 | denotes | androgen receptor |
T193 | 1090-1107 | P10275 | denotes | androgen receptor |
T194 | 1090-1107 | P19091 | denotes | androgen receptor |
T195 | 1090-1107 | PR:000004191 | denotes | androgen receptor |
T196 | 1090-1107 | O97960 | denotes | androgen receptor |
T197 | 1090-1107 | P15207 | denotes | androgen receptor |
T198 | 1090-1107 | O97952 | denotes | androgen receptor |
T199 | 1090-1107 | P49699 | denotes | androgen receptor |
T187 | 1090-1107 | D011944 | denotes | androgen receptor |
T200 | 1112-1131 | D011941 | denotes | adrenergic receptor |
T201 | 1137-1140 | 12618 | denotes | Cav |
T204 | 1137-1140 | 1051671 | denotes | Cav |
T209 | 1137-1142 | PR:Q03135 | denotes | Cav 1 |
T210 | 1137-1142 | PR:P35431 | denotes | Cav 1 |
T211 | 1137-1142 | PR:P49817 | denotes | Cav 1 |
T212 | 1137-1142 | PR:P93025 | denotes | Cav 1 |
T214 | 1137-1142 | PR:Q94051 | denotes | Cav 1 |
T215 | 1137-1142 | PR:000003198 | denotes | Cav 1 |
T216 | 1137-1142 | PR:P41350 | denotes | Cav 1 |
T213 | 1137-1142 | CVCL_KR36 | denotes | Cav 1 |
T227 | 1154-1189 | P25098 | denotes | G protein-coupled receptor kinase-2 |
T228 | 1154-1189 | PR:000003791 | denotes | G protein-coupled receptor kinase-2 |
T229 | 1154-1189 | Q99MK8 | denotes | G protein-coupled receptor kinase-2 |
T230 | 1154-1189 | P26817 | denotes | G protein-coupled receptor kinase-2 |
T231 | 1154-1189 | Q09639 | denotes | G protein-coupled receptor kinase-2 |
T232 | 1154-1189 | O97627 | denotes | G protein-coupled receptor kinase-2 |
T233 | 1154-1189 | P21146 | denotes | G protein-coupled receptor kinase-2 |
T235 | 1154-1189 | Q64682 | denotes | G protein-coupled receptor kinase-2 |
T236 | 1154-1189 | P32866 | denotes | G protein-coupled receptor kinase-2 |
T234 | 1154-1189 | D054769 | denotes | G protein-coupled receptor kinase-2 |
T241 | 1156-1163 | SO:0000104 | denotes | protein |
T237 | 1156-1163 | GO:0003675 | denotes | protein |
T243 | 1194-1200 | PR:000000947 | denotes | Kv 4.2 |
Allie
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
SS1_25037694_7_0 | 113-127 | expanded | denotes | left ventricle |
SS2_25037694_7_0 | 129-131 | abbr | denotes | LV |
SS1_25037694_9_0 | 397-425 | expanded | denotes | delayed afterdepolarizations |
SS2_25037694_9_0 | 427-431 | abbr | denotes | DADs |
SS1_25037694_10_0 | 587-613 | expanded | denotes | early afterdepolarizations |
SS2_25037694_10_0 | 615-619 | abbr | denotes | EADs |
AE1_25037694_7_0 | SS1_25037694_7_0 | SS2_25037694_7_0 | abbreviatedTo | left ventricle,LV |
AE1_25037694_9_0 | SS1_25037694_9_0 | SS2_25037694_9_0 | abbreviatedTo | delayed afterdepolarizations,DADs |
AE1_25037694_10_0 | SS1_25037694_10_0 | SS2_25037694_10_0 | abbreviatedTo | early afterdepolarizations,EADs |