PubMed:25006961
Annnotations
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 10101 | 11-20 | GeneOrGeneProduct | denotes | PKC-alpha | NCBIGene:18750 |
| 10102 | 32-39 | ChemicalEntity | denotes | lithium | MESH:D008094 |
| 10103 | 48-78 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | MESH:D018500 |
| 10104 | 80-87 | ChemicalEntity | denotes | Lithium | MESH:D008094 |
| 10105 | 125-155 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | MESH:D018500 |
| 10106 | 157-160 | DiseaseOrPhenotypicFeature | denotes | NDI | MESH:D018500 |
| 10107 | 173-181 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 10108 | 244-251 | ChemicalEntity | denotes | lithium | MESH:D008094 |
| 10109 | 275-279 | ChemicalEntity | denotes | cAMP | MESH:D000242 |
| 10110 | 313-329 | GeneOrGeneProduct | denotes | urea transporter | NCBIGene:27411 |
| 10111 | 331-336 | GeneOrGeneProduct | denotes | UT-A1 | NCBIGene:27411 |
| 10112 | 357-361 | GeneOrGeneProduct | denotes | AQP2 | NCBIGene:11827 |
| 10113 | 448-451 | GeneOrGeneProduct | denotes | PKC | NCBIGene:18750 |
| 10114 | 511-518 | ChemicalEntity | denotes | lithium | MESH:D008094 |
| 10115 | 527-535 | DiseaseOrPhenotypicFeature | denotes | polyuria | MESH:D011141 |
| 10116 | 537-546 | GeneOrGeneProduct | denotes | PKC-alpha | NCBIGene:18750 |
| 10117 | 552-556 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
| 10118 | 558-562 | GeneOrGeneProduct | denotes | PKCα | NCBIGene:18750 |
| 10119 | 628-635 | ChemicalEntity | denotes | lithium | MESH:D008094 |
| 10120 | 659-663 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
| 10121 | 760-764 | GeneOrGeneProduct | denotes | PKCα | NCBIGene:18750 |
| 10122 | 768-772 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
| 10123 | 857-861 | GeneOrGeneProduct | denotes | AQP2 | NCBIGene:11827 |
| 10124 | 931-935 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
| 10125 | 946-950 | GeneOrGeneProduct | denotes | AQP2 | NCBIGene:11827 |
| 10126 | 968-972 | GeneOrGeneProduct | denotes | PKCα | NCBIGene:18750 |
| 10127 | 1012-1017 | GeneOrGeneProduct | denotes | UT-A1 | NCBIGene:27411 |
| 10128 | 1061-1068 | ChemicalEntity | denotes | lithium | MESH:D008094 |
| 10129 | 1082-1089 | ChemicalEntity | denotes | Lithium | MESH:D008094 |
| 10130 | 1101-1105 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
| 10131 | 1157-1161 | GeneOrGeneProduct | denotes | PKCα | NCBIGene:18750 |
| 10132 | 1206-1210 | GeneOrGeneProduct | denotes | AQP2 | NCBIGene:11827 |
| 10133 | 1215-1220 | GeneOrGeneProduct | denotes | UT-A1 | NCBIGene:27411 |
| 10134 | 1254-1261 | ChemicalEntity | denotes | lithium | MESH:D008094 |
| 10135 | 1300-1304 | GeneOrGeneProduct | denotes | PKCα | NCBIGene:18750 |
| 10136 | 1308-1312 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
| 10137 | 1314-1318 | GeneOrGeneProduct | denotes | AQP2 | NCBIGene:11827 |
| 10138 | 1350-1355 | GeneOrGeneProduct | denotes | UT-A1 | NCBIGene:27411 |
| 10139 | 1391-1397 | ChemicalEntity | denotes | sodium | MESH:D012964 |
| 10140 | 1399-1408 | ChemicalEntity | denotes | potassium | MESH:D011188 |
| 10141 | 1413-1420 | ChemicalEntity | denotes | calcium | MESH:D002118 |
| 10142 | 1438-1445 | ChemicalEntity | denotes | lithium | MESH:D008094 |
| 10143 | 1464-1471 | ChemicalEntity | denotes | lithium | MESH:D008094 |
| 10144 | 1476-1480 | GeneOrGeneProduct | denotes | PKCα | NCBIGene:18750 |
| 10145 | 1484-1488 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
| 10146 | 1521-1525 | GeneOrGeneProduct | denotes | PKCα | NCBIGene:18750 |
| 10147 | 1536-1540 | GeneOrGeneProduct | denotes | AQP2 | NCBIGene:11827 |
| 10148 | 1545-1550 | GeneOrGeneProduct | denotes | UT-A1 | NCBIGene:27411 |
| 10149 | 1590-1597 | ChemicalEntity | denotes | lithium | MESH:D008094 |
| 10150 | 1606-1609 | DiseaseOrPhenotypicFeature | denotes | NDI | MESH:D018500 |
| 10151 | 1654-1662 | DiseaseOrPhenotypicFeature | denotes | polyuria | MESH:D011141 |
| 10152 | 1679-1686 | ChemicalEntity | denotes | lithium | MESH:D008094 |
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 552-556 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
| T3 | 659-663 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
| T5 | 768-772 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
| T7 | 931-935 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
| T9 | 1101-1105 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
| T11 | 1308-1312 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
| T13 | 1484-1488 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-79 | Sentence | denotes | Absence of PKC-alpha attenuates lithium-induced nephrogenic diabetes insipidus. |
| T2 | 80-182 | Sentence | denotes | Lithium, an effective antipsychotic, induces nephrogenic diabetes insipidus (NDI) in ∼40% of patients. |
| T3 | 183-395 | Sentence | denotes | The decreased capacity to concentrate urine is likely due to lithium acutely disrupting the cAMP pathway and chronically reducing urea transporter (UT-A1) and water channel (AQP2) expression in the inner medulla. |
| T4 | 396-536 | Sentence | denotes | Targeting an alternative signaling pathway, such as PKC-mediated signaling, may be an effective method of treating lithium-induced polyuria. |
| T5 | 537-655 | Sentence | denotes | PKC-alpha null mice (PKCα KO) and strain-matched wild type (WT) controls were treated with lithium for 0, 3 or 5 days. |
| T6 | 656-820 | Sentence | denotes | WT mice had increased urine output and lowered urine osmolality after 3 and 5 days of treatment whereas PKCα KO mice had no change in urine output or concentration. |
| T7 | 821-976 | Sentence | denotes | Western blot analysis revealed that AQP2 expression in medullary tissues was lowered after 3 and 5 days in WT mice; however, AQP2 was unchanged in PKCα KO. |
| T8 | 977-1029 | Sentence | denotes | Similar results were observed with UT-A1 expression. |
| T9 | 1030-1081 | Sentence | denotes | Animals were also treated with lithium for 6 weeks. |
| T10 | 1082-1205 | Sentence | denotes | Lithium-treated WT mice had 19-fold increased urine output whereas treated PKCα KO animals had a 4-fold increase in output. |
| T11 | 1206-1382 | Sentence | denotes | AQP2 and UT-A1 expression was lowered in 6 week lithium-treated WT animals whereas in treated PKCα KO mice, AQP2 was only reduced by 2-fold and UT-A1 expression was unaffected. |
| T12 | 1383-1489 | Sentence | denotes | Urinary sodium, potassium and calcium were elevated in lithium-fed WT but not in lithium-fed PKCα KO mice. |
| T13 | 1490-1695 | Sentence | denotes | Our data show that ablation of PKCα preserves AQP2 and UT-A1 protein expression and localization in lithium-induced NDI, and prevents the development of the severe polyuria associated with lithium therapy. |
LitCoin_Mondo
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 48-78 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | 0016383 |
| T2 | 60-78 | DiseaseOrPhenotypicFeature | denotes | diabetes insipidus | 0004782 |
| T3 | 125-155 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | 0016383 |
| T4 | 137-155 | DiseaseOrPhenotypicFeature | denotes | diabetes insipidus | 0004782 |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 11-20 | GeneOrGeneProduct | denotes | PKC-alpha |
| T2 | 21-31 | GeneOrGeneProduct | denotes | attenuates |
| T3 | 40-47 | GeneOrGeneProduct | denotes | induced |
| T4 | 48-78 | GeneOrGeneProduct | denotes | nephrogenic diabetes insipidus |
| T5 | 117-124 | GeneOrGeneProduct | denotes | induces |
| T6 | 125-155 | GeneOrGeneProduct | denotes | nephrogenic diabetes insipidus |
| T7 | 230-236 | GeneOrGeneProduct | denotes | likely |
| T8 | 260-270 | GeneOrGeneProduct | denotes | disrupting |
| T9 | 275-279 | GeneOrGeneProduct | denotes | cAMP |
| T10 | 304-312 | GeneOrGeneProduct | denotes | reducing |
| T11 | 313-329 | GeneOrGeneProduct | denotes | urea transporter |
| T12 | 331-336 | GeneOrGeneProduct | denotes | UT-A1 |
| T13 | 342-355 | GeneOrGeneProduct | denotes | water channel |
| T14 | 357-361 | GeneOrGeneProduct | denotes | AQP2 |
| T15 | 448-451 | GeneOrGeneProduct | denotes | PKC |
| T16 | 452-460 | GeneOrGeneProduct | denotes | mediated |
| T17 | 492-498 | GeneOrGeneProduct | denotes | method |
| T18 | 519-526 | GeneOrGeneProduct | denotes | induced |
| T19 | 537-546 | GeneOrGeneProduct | denotes | PKC-alpha |
| T20 | 547-551 | GeneOrGeneProduct | denotes | null |
| T21 | 552-556 | GeneOrGeneProduct | denotes | mice |
| T22 | 558-561 | GeneOrGeneProduct | denotes | PKC |
| T23 | 645-649 | GeneOrGeneProduct | denotes | or 5 |
| T24 | 659-663 | GeneOrGeneProduct | denotes | mice |
| T25 | 726-731 | GeneOrGeneProduct | denotes | 3 and |
| T26 | 760-763 | GeneOrGeneProduct | denotes | PKC |
| T27 | 768-772 | GeneOrGeneProduct | denotes | mice |
| T28 | 829-833 | GeneOrGeneProduct | denotes | blot |
| T29 | 857-861 | GeneOrGeneProduct | denotes | AQP2 |
| T30 | 912-917 | GeneOrGeneProduct | denotes | 3 and |
| T31 | 931-935 | GeneOrGeneProduct | denotes | mice |
| T32 | 946-950 | GeneOrGeneProduct | denotes | AQP2 |
| T33 | 968-971 | GeneOrGeneProduct | denotes | PKC |
| T34 | 977-984 | GeneOrGeneProduct | denotes | Similar |
| T35 | 1012-1017 | GeneOrGeneProduct | denotes | UT-A1 |
| T36 | 1101-1105 | GeneOrGeneProduct | denotes | mice |
| T37 | 1113-1117 | GeneOrGeneProduct | denotes | fold |
| T38 | 1157-1160 | GeneOrGeneProduct | denotes | PKC |
| T39 | 1173-1178 | GeneOrGeneProduct | denotes | had a |
| T40 | 1181-1185 | GeneOrGeneProduct | denotes | fold |
| T41 | 1206-1210 | GeneOrGeneProduct | denotes | AQP2 |
| T42 | 1215-1220 | GeneOrGeneProduct | denotes | UT-A1 |
| T43 | 1244-1248 | GeneOrGeneProduct | denotes | in 6 |
| T44 | 1300-1303 | GeneOrGeneProduct | denotes | PKC |
| T45 | 1308-1312 | GeneOrGeneProduct | denotes | mice |
| T46 | 1314-1318 | GeneOrGeneProduct | denotes | AQP2 |
| T47 | 1328-1335 | GeneOrGeneProduct | denotes | reduced |
| T48 | 1341-1345 | GeneOrGeneProduct | denotes | fold |
| T49 | 1350-1355 | GeneOrGeneProduct | denotes | UT-A1 |
| T50 | 1476-1479 | GeneOrGeneProduct | denotes | PKC |
| T51 | 1484-1488 | GeneOrGeneProduct | denotes | mice |
| T52 | 1521-1524 | GeneOrGeneProduct | denotes | PKC |
| T53 | 1536-1540 | GeneOrGeneProduct | denotes | AQP2 |
| T54 | 1545-1550 | GeneOrGeneProduct | denotes | UT-A1 |
| T55 | 1551-1558 | GeneOrGeneProduct | denotes | protein |
| T56 | 1598-1605 | GeneOrGeneProduct | denotes | induced |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 11-20 | GeneOrGeneProduct | denotes | PKC-alpha |
| T2 | 48-78 | GeneOrGeneProduct | denotes | nephrogenic diabetes insipidus |
| T3 | 125-155 | GeneOrGeneProduct | denotes | nephrogenic diabetes insipidus |
| T4 | 313-329 | GeneOrGeneProduct | denotes | urea transporter |
| T5 | 331-336 | GeneOrGeneProduct | denotes | UT-A1 |
| T6 | 342-355 | GeneOrGeneProduct | denotes | water channel |
| T7 | 357-361 | GeneOrGeneProduct | denotes | AQP2 |
| T8 | 448-451 | GeneOrGeneProduct | denotes | PKC |
| T9 | 492-498 | GeneOrGeneProduct | denotes | method |
| T10 | 537-546 | GeneOrGeneProduct | denotes | PKC-alpha |
| T11 | 547-551 | GeneOrGeneProduct | denotes | null |
| T12 | 558-561 | GeneOrGeneProduct | denotes | PKC |
| T13 | 760-763 | GeneOrGeneProduct | denotes | PKC |
| T14 | 829-833 | GeneOrGeneProduct | denotes | blot |
| T15 | 857-861 | GeneOrGeneProduct | denotes | AQP2 |
| T16 | 946-950 | GeneOrGeneProduct | denotes | AQP2 |
| T17 | 968-971 | GeneOrGeneProduct | denotes | PKC |
| T18 | 977-984 | GeneOrGeneProduct | denotes | Similar |
| T19 | 1012-1017 | GeneOrGeneProduct | denotes | UT-A1 |
| T20 | 1113-1117 | GeneOrGeneProduct | denotes | fold |
| T21 | 1157-1160 | GeneOrGeneProduct | denotes | PKC |
| T22 | 1181-1185 | GeneOrGeneProduct | denotes | fold |
| T23 | 1206-1210 | GeneOrGeneProduct | denotes | AQP2 |
| T24 | 1215-1220 | GeneOrGeneProduct | denotes | UT-A1 |
| T25 | 1300-1303 | GeneOrGeneProduct | denotes | PKC |
| T26 | 1314-1318 | GeneOrGeneProduct | denotes | AQP2 |
| T27 | 1328-1335 | GeneOrGeneProduct | denotes | reduced |
| T28 | 1341-1345 | GeneOrGeneProduct | denotes | fold |
| T29 | 1350-1355 | GeneOrGeneProduct | denotes | UT-A1 |
| T30 | 1476-1479 | GeneOrGeneProduct | denotes | PKC |
| T31 | 1521-1524 | GeneOrGeneProduct | denotes | PKC |
| T32 | 1536-1540 | GeneOrGeneProduct | denotes | AQP2 |
| T33 | 1545-1550 | GeneOrGeneProduct | denotes | UT-A1 |
| T34 | 1551-1558 | GeneOrGeneProduct | denotes | protein |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 48-78 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | D018500 |
| T2 | 125-155 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | D018500 |
| T3 | 527-535 | DiseaseOrPhenotypicFeature | denotes | polyuria | D011141 |
| T4 | 571-577 | DiseaseOrPhenotypicFeature | denotes | strain | D013180 |
| T5 | 1654-1662 | DiseaseOrPhenotypicFeature | denotes | polyuria | D011141 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 11-20 | GeneOrGeneProduct | denotes | PKC-alpha |
| T2 | 48-78 | GeneOrGeneProduct | denotes | nephrogenic diabetes insipidus |
| T3 | 125-155 | GeneOrGeneProduct | denotes | nephrogenic diabetes insipidus |
| T4 | 157-160 | GeneOrGeneProduct | denotes | NDI |
| T5 | 313-329 | GeneOrGeneProduct | denotes | urea transporter |
| T6 | 331-336 | GeneOrGeneProduct | denotes | UT-A1 |
| T7 | 342-355 | GeneOrGeneProduct | denotes | water channel |
| T8 | 357-361 | GeneOrGeneProduct | denotes | AQP2 |
| T9 | 448-451 | GeneOrGeneProduct | denotes | PKC |
| T10 | 537-546 | GeneOrGeneProduct | denotes | PKC-alpha |
| T11 | 558-561 | GeneOrGeneProduct | denotes | PKC |
| T12 | 760-763 | GeneOrGeneProduct | denotes | PKC |
| T13 | 857-861 | GeneOrGeneProduct | denotes | AQP2 |
| T14 | 946-950 | GeneOrGeneProduct | denotes | AQP2 |
| T15 | 968-971 | GeneOrGeneProduct | denotes | PKC |
| T16 | 1012-1017 | GeneOrGeneProduct | denotes | UT-A1 |
| T17 | 1157-1160 | GeneOrGeneProduct | denotes | PKC |
| T18 | 1206-1210 | GeneOrGeneProduct | denotes | AQP2 |
| T19 | 1215-1220 | GeneOrGeneProduct | denotes | UT-A1 |
| T20 | 1300-1303 | GeneOrGeneProduct | denotes | PKC |
| T21 | 1314-1318 | GeneOrGeneProduct | denotes | AQP2 |
| T22 | 1350-1355 | GeneOrGeneProduct | denotes | UT-A1 |
| T23 | 1476-1479 | GeneOrGeneProduct | denotes | PKC |
| T24 | 1521-1524 | GeneOrGeneProduct | denotes | PKC |
| T25 | 1536-1540 | GeneOrGeneProduct | denotes | AQP2 |
| T26 | 1545-1550 | GeneOrGeneProduct | denotes | UT-A1 |
| T27 | 1551-1569 | GeneOrGeneProduct | denotes | protein expression |
| T28 | 1606-1609 | GeneOrGeneProduct | denotes | NDI |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 48-78 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | 0016383 |
| T2 | 125-155 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | 0016383 |
| T3 | 1446-1449 | DiseaseOrPhenotypicFeature | denotes | fed | 0007620 |
| T4 | 1472-1475 | DiseaseOrPhenotypicFeature | denotes | fed | 0007620 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 48-78 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | D018500 |
| T2 | 125-155 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | D018500 |
| T3 | 527-535 | DiseaseOrPhenotypicFeature | denotes | polyuria | D011141 |
| T4 | 571-577 | DiseaseOrPhenotypicFeature | denotes | strain | D013180 |
| T5 | 1654-1662 | DiseaseOrPhenotypicFeature | denotes | polyuria | D011141 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 48-78 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | D018500 |
| T2 | 125-155 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | D018500 |
| T3 | 527-535 | DiseaseOrPhenotypicFeature | denotes | polyuria | D011141 |
| T4 | 1654-1662 | DiseaseOrPhenotypicFeature | denotes | polyuria | D011141 |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 32-39 | ChemicalEntity | denotes | lithium | D008094|http://purl.obolibrary.org/obo/CHEBI_30145 |
| T3 | 80-87 | ChemicalEntity | denotes | Lithium | http://purl.obolibrary.org/obo/CHEBI_30145 |
| T4 | 244-251 | ChemicalEntity | denotes | lithium | D008094|http://purl.obolibrary.org/obo/CHEBI_30145 |
| T6 | 275-279 | ChemicalEntity | denotes | cAMP | http://purl.obolibrary.org/obo/CHEBI_17489 |
| T7 | 313-317 | ChemicalEntity | denotes | urea | D014508|http://purl.obolibrary.org/obo/CHEBI_16199 |
| T9 | 342-347 | ChemicalEntity | denotes | water | D014867|http://purl.obolibrary.org/obo/CHEBI_15377 |
| T11 | 511-518 | ChemicalEntity | denotes | lithium | D008094|http://purl.obolibrary.org/obo/CHEBI_30145 |
| T13 | 628-635 | ChemicalEntity | denotes | lithium | D008094|http://purl.obolibrary.org/obo/CHEBI_30145 |
| T15 | 1061-1068 | ChemicalEntity | denotes | lithium | D008094|http://purl.obolibrary.org/obo/CHEBI_30145 |
| T17 | 1082-1089 | ChemicalEntity | denotes | Lithium | http://purl.obolibrary.org/obo/CHEBI_30145 |
| T18 | 1254-1261 | ChemicalEntity | denotes | lithium | D008094|http://purl.obolibrary.org/obo/CHEBI_30145 |
| T20 | 1391-1397 | ChemicalEntity | denotes | sodium | D012964|http://purl.obolibrary.org/obo/CHEBI_26708 |
| T22 | 1399-1408 | ChemicalEntity | denotes | potassium | D011188|http://purl.obolibrary.org/obo/CHEBI_26216 |
| T24 | 1413-1420 | ChemicalEntity | denotes | calcium | D002118|http://purl.obolibrary.org/obo/CHEBI_29320|http://purl.obolibrary.org/obo/CHEBI_22984 |
| T27 | 1438-1445 | ChemicalEntity | denotes | lithium | D008094|http://purl.obolibrary.org/obo/CHEBI_30145 |
| T29 | 1464-1471 | ChemicalEntity | denotes | lithium | D008094|http://purl.obolibrary.org/obo/CHEBI_30145 |
| T31 | 1590-1597 | ChemicalEntity | denotes | lithium | D008094|http://purl.obolibrary.org/obo/CHEBI_30145 |
| T33 | 1679-1686 | ChemicalEntity | denotes | lithium | D008094|http://purl.obolibrary.org/obo/CHEBI_30145 |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 173-181 | OrganismTaxon | denotes | patients |
| T2 | 552-556 | OrganismTaxon | denotes | mice |
| T3 | 659-663 | OrganismTaxon | denotes | mice |
| T4 | 768-772 | OrganismTaxon | denotes | mice |
| T5 | 931-935 | OrganismTaxon | denotes | mice |
| T6 | 1101-1105 | OrganismTaxon | denotes | mice |
| T7 | 1308-1312 | OrganismTaxon | denotes | mice |
| T8 | 1484-1488 | OrganismTaxon | denotes | mice |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T33 | 1679-1686 | ChemicalEntity | denotes | lithium | http://purl.obolibrary.org/obo/CHEBI_30145|D008094 | |
| T31 | 1590-1597 | ChemicalEntity | denotes | lithium | http://purl.obolibrary.org/obo/CHEBI_30145|D008094 | |
| T29 | 1464-1471 | ChemicalEntity | denotes | lithium | http://purl.obolibrary.org/obo/CHEBI_30145|D008094 | |
| T27 | 1438-1445 | ChemicalEntity | denotes | lithium | http://purl.obolibrary.org/obo/CHEBI_30145|D008094 | |
| T24 | 1413-1420 | ChemicalEntity | denotes | calcium | http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320|D002118 | |
| T22 | 1399-1408 | ChemicalEntity | denotes | potassium | http://purl.obolibrary.org/obo/CHEBI_26216|D011188 | |
| T20 | 1391-1397 | ChemicalEntity | denotes | sodium | http://purl.obolibrary.org/obo/CHEBI_26708|D012964 | |
| T18 | 1254-1261 | ChemicalEntity | denotes | lithium | http://purl.obolibrary.org/obo/CHEBI_30145|D008094 | |
| T17 | 1082-1089 | ChemicalEntity | denotes | Lithium | http://purl.obolibrary.org/obo/CHEBI_30145 | |
| T15 | 1061-1068 | ChemicalEntity | denotes | lithium | http://purl.obolibrary.org/obo/CHEBI_30145|D008094 | |
| T13 | 628-635 | ChemicalEntity | denotes | lithium | http://purl.obolibrary.org/obo/CHEBI_30145|D008094 | |
| T11 | 511-518 | ChemicalEntity | denotes | lithium | http://purl.obolibrary.org/obo/CHEBI_30145|D008094 | |
| T9 | 342-347 | ChemicalEntity | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377|D014867 | |
| T7 | 313-317 | ChemicalEntity | denotes | urea | http://purl.obolibrary.org/obo/CHEBI_16199|D014508 | |
| T6 | 275-279 | ChemicalEntity | denotes | cAMP | http://purl.obolibrary.org/obo/CHEBI_17489 | |
| T4 | 244-251 | ChemicalEntity | denotes | lithium | http://purl.obolibrary.org/obo/CHEBI_30145|D008094 | |
| T3 | 80-87 | ChemicalEntity | denotes | Lithium | http://purl.obolibrary.org/obo/CHEBI_30145 | |
| T1 | 32-39 | ChemicalEntity | denotes | lithium | http://purl.obolibrary.org/obo/CHEBI_30145|D008094 | |
| T28 | 1606-1609 | GeneOrGeneProduct | denotes | NDI | ||
| T22081 | 1551-1569 | GeneOrGeneProduct | denotes | protein expression | ||
| T26 | 1545-1550 | GeneOrGeneProduct | denotes | UT-A1 | ||
| T25 | 1536-1540 | GeneOrGeneProduct | denotes | AQP2 | ||
| T11973 | 1521-1524 | GeneOrGeneProduct | denotes | PKC | ||
| T23 | 1476-1479 | GeneOrGeneProduct | denotes | PKC | ||
| T33594 | 1350-1355 | GeneOrGeneProduct | denotes | UT-A1 | ||
| T21 | 1314-1318 | GeneOrGeneProduct | denotes | AQP2 | ||
| T4548 | 1300-1303 | GeneOrGeneProduct | denotes | PKC | ||
| T19 | 1215-1220 | GeneOrGeneProduct | denotes | UT-A1 | ||
| T75716 | 1206-1210 | GeneOrGeneProduct | denotes | AQP2 | ||
| T65105 | 1157-1160 | GeneOrGeneProduct | denotes | PKC | ||
| T16 | 1012-1017 | GeneOrGeneProduct | denotes | UT-A1 | ||
| T67104 | 968-971 | GeneOrGeneProduct | denotes | PKC | ||
| T14 | 946-950 | GeneOrGeneProduct | denotes | AQP2 | ||
| T25528 | 857-861 | GeneOrGeneProduct | denotes | AQP2 | ||
| T12 | 760-763 | GeneOrGeneProduct | denotes | PKC | ||
| T45944 | 558-561 | GeneOrGeneProduct | denotes | PKC | ||
| T10 | 537-546 | GeneOrGeneProduct | denotes | PKC-alpha | ||
| T86269 | 448-451 | GeneOrGeneProduct | denotes | PKC | ||
| T8 | 357-361 | GeneOrGeneProduct | denotes | AQP2 | ||
| T35176 | 342-355 | GeneOrGeneProduct | denotes | water channel | ||
| T54732 | 331-336 | GeneOrGeneProduct | denotes | UT-A1 | ||
| T5 | 313-329 | GeneOrGeneProduct | denotes | urea transporter | ||
| T4389 | 157-160 | GeneOrGeneProduct | denotes | NDI | ||
| T45224 | 125-155 | GeneOrGeneProduct | denotes | nephrogenic diabetes insipidus | ||
| T2 | 48-78 | GeneOrGeneProduct | denotes | nephrogenic diabetes insipidus | ||
| T93515 | 11-20 | GeneOrGeneProduct | denotes | PKC-alpha | ||
| T23155 | 1654-1662 | DiseaseOrPhenotypicFeature | denotes | polyuria | D011141 | |
| T23820 | 527-535 | DiseaseOrPhenotypicFeature | denotes | polyuria | D011141 | |
| T50659 | 125-155 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | D018500 | |
| T76238 | 48-78 | DiseaseOrPhenotypicFeature | denotes | nephrogenic diabetes insipidus | D018500 | |
| T57480 | 1484-1488 | OrganismTaxon | denotes | mice | ||
| T81775 | 1308-1312 | OrganismTaxon | denotes | mice | ||
| T44401 | 1101-1105 | OrganismTaxon | denotes | mice | ||
| T46540 | 931-935 | OrganismTaxon | denotes | mice | ||
| T52672 | 768-772 | OrganismTaxon | denotes | mice | ||
| T44204 | 659-663 | OrganismTaxon | denotes | mice | ||
| T25051 | 552-556 | OrganismTaxon | denotes | mice | ||
| T77383 | 173-181 | OrganismTaxon | denotes | patients |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 125-155 | HP_0009806 | denotes | nephrogenic diabetes insipidus |
| T2 | 137-155 | HP_0000873 | denotes | diabetes insipidus |
| T3 | 527-535 | HP_0000103 | denotes | polyuria |
| T4 | 668-690 | HP_0000103 | denotes | increased urine output |
| T5 | 1118-1140 | HP_0000103 | denotes | increased urine output |
| T6 | 1654-1662 | HP_0000103 | denotes | polyuria |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_25006961_1_0 | 125-155 | expanded | denotes | nephrogenic diabetes insipidus |
| SS2_25006961_1_0 | 157-160 | abbr | denotes | NDI |
| SS1_25006961_4_0 | 586-595 | expanded | denotes | wild type |
| SS2_25006961_4_0 | 597-599 | abbr | denotes | WT |
| AE1_25006961_1_0 | SS1_25006961_1_0 | SS2_25006961_1_0 | abbreviatedTo | nephrogenic diabetes insipidus,NDI |
| AE1_25006961_4_0 | SS1_25006961_4_0 | SS2_25006961_4_0 | abbreviatedTo | wild type,WT |