PubMed:24996171 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/24996171","sourcedb":"PubMed","sourceid":"24996171","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/24996171","text":"Laryngeal cancer in Finland: A 5-year follow-up study of 366 patients.\nBACKGROUND: The purpose of this study was to acquire nationwide data on the management and outcome of laryngeal squamous cell carcinoma (SCC) in Finnish university hospitals over a 5-year posttreatment follow-up.\nMETHODS: All records of patients diagnosed and treated for primary laryngeal SCC during 2001 to 2005 were reviewed.\nRESULTS: Three hundred sixty-six patients with laryngeal cancer were identified, 360 of whom had laryngeal SCC. Three hundred forty-two patients with laryngeal SCC (95%) were treated with curative intent. Five-year disease-specific survival (DSS) for T1a, T1b, T2, T3, and T4 glottic SCC was 100%, 95%, 78%, 79%, and 53%, respectively. The corresponding figures for T1 to T4 supraglottic SCC were 68%, 54%, 72%, and 59%.\nCONCLUSION: Results of this nationwide study give a general overview of the outcome of unselected patients treated with unified guidelines. Patients with T2 tumors, usually treated with radiotherapy (RT), had a worse prognosis than expected. This patient group warrants further investigation and possibly treatment intensification. © 2015 Wiley Periodicals, Inc. Head Neck 38: 36-43, 2016.","tracks":[]}