PubMed:24945498 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/24945498","sourcedb":"PubMed","sourceid":"24945498","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/24945498","text":"Molecular and Serological Intraocular Fluid Analysis of Coxiella burnetii-seropositive Patients with Concurrent Idiopathic Uveitis.\nPURPOSE: Previous studies have suggested a link between Q fever and uveitis. We determined whether Coxiella burnetii causes intraocular infection in C. burnetii-seropositive patients with idiopathic uveitis.\nMETHODS: From a retrospective observational case series, paired aqueous humor and serum samples from 10 C. burnetii-seropositive patients with idiopathic uveitis were examined for intraocular antibody production by using the Goldmann-Witmer coefficient and by polymerase chain reaction (PCR).\nRESULTS: Although intraocular IgG against C. burnetii was detected, no intraocular antibody production was observed (low Goldmann Wittmer coefficients). All PCR results were negative.\nCONCLUSIONS: Uveitis due to an intraocular infection with C. burnetii is unlikely.","tracks":[]}