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PubMed:24897237 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-91 Sentence denotes Interleukin-18 gene promoter--607 A/C polymorphism and the risk of immune thrombocytopenia.
TextSentencer_T2 92-209 Sentence denotes Interleukin-18 (IL-18) is a T helper 1 cytokine, which is postulated to play a role in immune thrombocytopenia (ITP).
TextSentencer_T3 210-323 Sentence denotes The aim of this study was to determine whether IL-18 promoter gene -607 A/C polymorphism was associated with ITP.
TextSentencer_T4 324-424 Sentence denotes Three-hundred and fifty-four Chinese ITP patients and 300 Chinese healthy individuals were enrolled.
TextSentencer_T5 425-477 Sentence denotes Genomic DNA was extracted from the peripheral blood.
TextSentencer_T6 478-634 Sentence denotes Polymerase chain reaction-restriction fragment length polymorphism (RFLP) was used to genotype the DNA samples for single nucleotide polymorphism (SNP)-607.
TextSentencer_T7 635-738 Sentence denotes Allelic and genotypic frequencies were compared between the case-control groups by the chi-square test.
TextSentencer_T8 739-950 Sentence denotes The results showed that the frequencies of the CC, CA and AA genotypes and C and A allele were 32.4, 47.8, 19.8, 56.4 and 43.6% in ITP patients and 32.3, 50.4, 17.3, 57.5 and 42.5% in the controls, respectively.
TextSentencer_T9 951-1069 Sentence denotes There was no significant difference in either genotypes or allelic distribution between ITP patients and the controls.
TextSentencer_T10 1070-1348 Sentence denotes Furthermore, stratified analysis by the platelet count, age and disease course including ITP with severe thrombocytopenia (sITP), non-sITP, acute adult, chronic adult, acute childhood and chronic childhood revealed no significant difference in genotype and alleles distribution.
TextSentencer_T11 1349-1451 Sentence denotes In conclusion, this polymorphism was almost equally distributed between ITP patients and the controls.
TextSentencer_T12 1452-1572 Sentence denotes These data showed that this SNP may not be used as a stratification marker to predict the susceptibility to Chinese ITP.
T1 0-91 Sentence denotes Interleukin-18 gene promoter--607 A/C polymorphism and the risk of immune thrombocytopenia.
T2 92-209 Sentence denotes Interleukin-18 (IL-18) is a T helper 1 cytokine, which is postulated to play a role in immune thrombocytopenia (ITP).
T3 210-323 Sentence denotes The aim of this study was to determine whether IL-18 promoter gene -607 A/C polymorphism was associated with ITP.
T4 324-424 Sentence denotes Three-hundred and fifty-four Chinese ITP patients and 300 Chinese healthy individuals were enrolled.
T5 425-477 Sentence denotes Genomic DNA was extracted from the peripheral blood.
T6 478-634 Sentence denotes Polymerase chain reaction-restriction fragment length polymorphism (RFLP) was used to genotype the DNA samples for single nucleotide polymorphism (SNP)-607.
T7 635-738 Sentence denotes Allelic and genotypic frequencies were compared between the case-control groups by the chi-square test.
T8 739-950 Sentence denotes The results showed that the frequencies of the CC, CA and AA genotypes and C and A allele were 32.4, 47.8, 19.8, 56.4 and 43.6% in ITP patients and 32.3, 50.4, 17.3, 57.5 and 42.5% in the controls, respectively.
T9 951-1069 Sentence denotes There was no significant difference in either genotypes or allelic distribution between ITP patients and the controls.
T10 1070-1348 Sentence denotes Furthermore, stratified analysis by the platelet count, age and disease course including ITP with severe thrombocytopenia (sITP), non-sITP, acute adult, chronic adult, acute childhood and chronic childhood revealed no significant difference in genotype and alleles distribution.
T11 1349-1451 Sentence denotes In conclusion, this polymorphism was almost equally distributed between ITP patients and the controls.
T12 1452-1572 Sentence denotes These data showed that this SNP may not be used as a stratification marker to predict the susceptibility to Chinese ITP.

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 179-202 HP_0001973 denotes immune thrombocytopenia
T2 186-202 HP_0001873 denotes thrombocytopenia
T3 1175-1191 HP_0001873 denotes thrombocytopenia

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
24897237-0#0#14#gene3606 0-14 gene3606 denotes Interleukin-18
24897237-0#67#90#diseaseC0242584 67-90 diseaseC0242584 denotes immune thrombocytopenia
24897237-0#67#90#diseaseC0272286 67-90 diseaseC0272286 denotes immune thrombocytopenia
24897237-0#67#90#diseaseC0398650 67-90 diseaseC0398650 denotes immune thrombocytopenia
0#14#gene360667#90#diseaseC0242584 24897237-0#0#14#gene3606 24897237-0#67#90#diseaseC0242584 associated_with Interleukin-18,immune thrombocytopenia
0#14#gene360667#90#diseaseC0272286 24897237-0#0#14#gene3606 24897237-0#67#90#diseaseC0272286 associated_with Interleukin-18,immune thrombocytopenia
0#14#gene360667#90#diseaseC0398650 24897237-0#0#14#gene3606 24897237-0#67#90#diseaseC0398650 associated_with Interleukin-18,immune thrombocytopenia

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2485 0-14 gene:3606 denotes Interleukin-18
T2486 67-90 disease:C0242584 denotes immune thrombocytopenia
R1 T2485 T2486 associated_with Interleukin-18,immune thrombocytopenia
R2 T2485 T2486 associated_with Interleukin-18,immune thrombocytopenia
R3 T2485 T2486 associated_with Interleukin-18,immune thrombocytopenia

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 471-476 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 471-476 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood