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PubMed:24866022 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-107 Sentence denotes The effect of Na-selenite treatment on the oxidative stress-antioxidants balance of multiple organ failure.
T2 108-116 Sentence denotes PURPOSE:
T3 117-330 Sentence denotes Our study tested the hypothesis that sodium (Na)-selenite expression treatment can reduce oxidative stress and increase plasma antioxidants, whereas modulating white blood cell antigen expression in severe sepsis.
T4 331-484 Sentence denotes Selenite is a well known cofactor of glutathione peroxidases and other antioxidant enzymes; therefore, one may expect an antioxidant effect of treatment.
T5 485-495 Sentence denotes MATERIALS:
T6 496-570 Sentence denotes We randomized 40 severe septic patients into treatment and control groups.
T7 571-676 Sentence denotes Treatment group (n = 21) received 1000-μg/2 hours Na-selenite load, followed by a 1000-μg/die medication.
T8 677-900 Sentence denotes Oxidative stress markers, including malondialdehyde, maximal free radical production, and plasma antioxidants: free sulfhydryl groups, glutathione levels, and superoxide dismutase and catalase enzyme activity were measured.
T9 901-909 Sentence denotes RESULTS:
T10 910-1001 Sentence denotes According to our results, the treatment regime successfully restored serum selenium levels.
T11 1002-1158 Sentence denotes Treatment group developed a significant malondialdehyde increase by the fifth study day, whereas reactive oxygen species production decreased significantly.
T12 1159-1241 Sentence denotes Reduced glutathione and plasma sulfhydryl groups showed no significant difference.
T13 1242-1372 Sentence denotes Treatment group showed deteriorated expression of CD11a and slight increase of CD49d expression on monocytes throughout our study.
T14 1373-1385 Sentence denotes CONCLUSIONS:
T15 1386-1624 Sentence denotes Although our Na-selenite treatment regime successfully restored the selenium deficiency of severe septic patients, antioxidant and white blood cell antigen expression modulating effect of the therapy was not observed in our patient group.
T1 0-107 Sentence denotes The effect of Na-selenite treatment on the oxidative stress-antioxidants balance of multiple organ failure.
T2 108-116 Sentence denotes PURPOSE:
T3 117-330 Sentence denotes Our study tested the hypothesis that sodium (Na)-selenite expression treatment can reduce oxidative stress and increase plasma antioxidants, whereas modulating white blood cell antigen expression in severe sepsis.
T4 331-484 Sentence denotes Selenite is a well known cofactor of glutathione peroxidases and other antioxidant enzymes; therefore, one may expect an antioxidant effect of treatment.
T5 485-495 Sentence denotes MATERIALS:
T6 496-570 Sentence denotes We randomized 40 severe septic patients into treatment and control groups.
T7 571-676 Sentence denotes Treatment group (n = 21) received 1000-μg/2 hours Na-selenite load, followed by a 1000-μg/die medication.
T8 677-900 Sentence denotes Oxidative stress markers, including malondialdehyde, maximal free radical production, and plasma antioxidants: free sulfhydryl groups, glutathione levels, and superoxide dismutase and catalase enzyme activity were measured.
T9 901-909 Sentence denotes RESULTS:
T10 910-1001 Sentence denotes According to our results, the treatment regime successfully restored serum selenium levels.
T11 1002-1158 Sentence denotes Treatment group developed a significant malondialdehyde increase by the fifth study day, whereas reactive oxygen species production decreased significantly.
T12 1159-1241 Sentence denotes Reduced glutathione and plasma sulfhydryl groups showed no significant difference.
T13 1242-1372 Sentence denotes Treatment group showed deteriorated expression of CD11a and slight increase of CD49d expression on monocytes throughout our study.
T14 1373-1385 Sentence denotes CONCLUSIONS:
T15 1386-1624 Sentence denotes Although our Na-selenite treatment regime successfully restored the selenium deficiency of severe septic patients, antioxidant and white blood cell antigen expression modulating effect of the therapy was not observed in our patient group.

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 323-329 HP_0100806 denotes sepsis

yaoziqian_800_3

Id Subject Object Predicate Lexical cue
T1 14-25 CI denotes Na-selenite
T2 621-632 CI denotes Na-selenite
T3 1399-1410 CI denotes Na-selenite
T4 154-174 CI denotes sodium (Na)-selenite
T8 513-526 DP denotes severe septic
T9 1477-1490 DP denotes severe septic
T10 316-329 DP denotes severe sepsis
T11 331-339 CI denotes Selenite

Zierdiyeerkenaili_800_3

Id Subject Object Predicate Lexical cue
T1 14-25 CI denotes Na-selenite
T2 621-632 CI denotes Na-selenite
T3 1399-1410 CI denotes Na-selenite
T5 513-526 DP denotes severe septic
T6 1477-1490 DP denotes severe septic
T7 316-329 DP denotes severe sepsis
T8 331-339 CI denotes Selenite
T9 154-174 CI denotes sodium (Na)-selenite