| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-198 |
Sentence |
denotes |
Determination of the epitope specificity of monoclonal antibodies against the inner core region of bacterial lipopolysaccharides by use of 3-deoxy-D-manno-octulosonate-containing synthetic antigens. |
| TextSentencer_T2 |
199-514 |
Sentence |
denotes |
Partial structures of enterobacterial lipopolysaccharides (LPS) of the Rechemotype, consisting of lipid A and 3-deoxy-D-manno-2-octulosonic acid (Kdo), as well as oligosaccharides and derivative of Kdo were synthesized and used to characterize the epitope specificity of monoclonal antibodies against Re-mutant LPS. |
| TextSentencer_T3 |
515-742 |
Sentence |
denotes |
High-molecular-weight antigens, obtained after copolymerization of the respective allyl glycosides with acrylamide, and the haptenic oligosaccharides were used in immunoprecipitation, immune hemolysis, and in inhibition assays. |
| TextSentencer_T4 |
743-963 |
Sentence |
denotes |
A monoclonal antibody (clone 20, igM) recognizing a terminal Kdop group was shown to require for its binding the alpha-anomeric configuration and OH-4 and OH-5 groups, whereas the C-7 - C-8 chain was of minor importance. |
| TextSentencer_T5 |
964-1148 |
Sentence |
denotes |
Another monoclonal antibody (clone 25, IgG3), which recognizes a (2--4)-linked Kdo disaccharide, was shown to require for its binding the alpha-anomeric configuration of both residues. |
| TextSentencer_T6 |
1149-1290 |
Sentence |
denotes |
The isomer having a reducing beta-Kdo residue was significantly less active, and that with a terminal beta-Kdo group was completely inactive. |
| TextSentencer_T7 |
1291-1483 |
Sentence |
denotes |
The OH-5 group of the reducing residue was shown to be not important for the specificity of this antibody, since it could be replaced by a hydrogen atom without loss of serological reactivity. |
| TextSentencer_T8 |
1484-1583 |
Sentence |
denotes |
The alpha-(2--8)-linked Kdo disaccharide was strongly cross-reactive with its (2--4)-linked isomer. |
| TextSentencer_T9 |
1584-1672 |
Sentence |
denotes |
The antibody recognized also parts of the 2-amino-2-deoxy-D-glucose backbone of lipid A. |
| T1 |
0-198 |
Sentence |
denotes |
Determination of the epitope specificity of monoclonal antibodies against the inner core region of bacterial lipopolysaccharides by use of 3-deoxy-D-manno-octulosonate-containing synthetic antigens. |
| T2 |
199-514 |
Sentence |
denotes |
Partial structures of enterobacterial lipopolysaccharides (LPS) of the Rechemotype, consisting of lipid A and 3-deoxy-D-manno-2-octulosonic acid (Kdo), as well as oligosaccharides and derivative of Kdo were synthesized and used to characterize the epitope specificity of monoclonal antibodies against Re-mutant LPS. |
| T3 |
515-742 |
Sentence |
denotes |
High-molecular-weight antigens, obtained after copolymerization of the respective allyl glycosides with acrylamide, and the haptenic oligosaccharides were used in immunoprecipitation, immune hemolysis, and in inhibition assays. |
| T4 |
743-963 |
Sentence |
denotes |
A monoclonal antibody (clone 20, igM) recognizing a terminal Kdop group was shown to require for its binding the alpha-anomeric configuration and OH-4 and OH-5 groups, whereas the C-7 - C-8 chain was of minor importance. |
| T5 |
964-1148 |
Sentence |
denotes |
Another monoclonal antibody (clone 25, IgG3), which recognizes a (2--4)-linked Kdo disaccharide, was shown to require for its binding the alpha-anomeric configuration of both residues. |
| T6 |
1149-1290 |
Sentence |
denotes |
The isomer having a reducing beta-Kdo residue was significantly less active, and that with a terminal beta-Kdo group was completely inactive. |
| T7 |
1291-1483 |
Sentence |
denotes |
The OH-5 group of the reducing residue was shown to be not important for the specificity of this antibody, since it could be replaced by a hydrogen atom without loss of serological reactivity. |
| T8 |
1484-1583 |
Sentence |
denotes |
The alpha-(2--8)-linked Kdo disaccharide was strongly cross-reactive with its (2--4)-linked isomer. |
| T9 |
1584-1672 |
Sentence |
denotes |
The antibody recognized also parts of the 2-amino-2-deoxy-D-glucose backbone of lipid A. |
