PubMed:24739405 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/24739405","sourcedb":"PubMed","sourceid":"24739405","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/24739405","text":"Effects of dehydroepiandrosterone in amphetamine-induced schizophrenia models in mice.\nOBJECTIVE: To examine the effects of dehydroepiandrosterone (DHEA) on animal models of schizophrenia.\nMETHODS: Seventy Swiss albino female mice (25-35 g) were divided into 4 groups: amphetamine-free (control), amphetamine, 50, and 100 mg/kg DHEA. The DHEA was administered intraperitoneally (ip) for 5 days. Amphetamine (3 mg/kg ip) induced hyper locomotion, apomorphine (1.5 mg/kg subcutaneously [sc]) induced climbing, and haloperidol (1.5 mg/kg sc) induced catalepsy tests were used as animal models of schizophrenia. The study was conducted at the Animal Experiment Laboratories, Department of Pharmacology, Medical School, Eskisehir Osmangazi University, Eskisehir, Turkey between March and May 2012. Statistical analysis was carried out using Kruskal-Wallis test for hyper locomotion, and one-way ANOVA for climbing and catalepsy tests.\nRESULTS: In the amphetamine-induced locomotion test, there were significant increases in all movements compared with the amphetamine-free group. Both DHEA 50 mg/kg (p\u003c0.05), and 100 mg/kg (p\u003c0.01) significantly decreased all movements compared with the amphetamine-induced locomotion group. There was a significant difference between groups in the haloperidol-induced catalepsy test (p\u003c0.05). There was no significant difference between groups in terms of total climbing time in the apomorphine-induced climbing test (p\u003e0.05).\nCONCLUSION: We observed that DHEA reduced locomotor activity and increased catalepsy at both doses, while it had no effect on climbing behavior. We suggest that DHEA displays typical neuroleptic-like effects, and may be used in the treatment of schizophrenia.","tracks":[{"project":"TEST-DiseaseOrPhenotypicFeature","denotations":[{"id":"T1","span":{"begin":57,"end":70},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":174,"end":187},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":547,"end":556},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":593,"end":606},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":913,"end":922},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1298,"end":1307},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":1532,"end":1541},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":1702,"end":1715},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A4","pred":"#label","subj":"T4","obj":"D012559"},{"id":"A7","pred":"#label","subj":"T7","obj":"D002375"},{"id":"A1","pred":"#label","subj":"T1","obj":"D012559"},{"id":"A3","pred":"#label","subj":"T3","obj":"D002375"},{"id":"A5","pred":"#label","subj":"T5","obj":"D002375"},{"id":"A2","pred":"#label","subj":"T2","obj":"D012559"},{"id":"A8","pred":"#label","subj":"T8","obj":"D012559"},{"id":"A6","pred":"#label","subj":"T6","obj":"D002375"},{"subj":"T1","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T2","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T3","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T4","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T5","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T6","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T7","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"},{"subj":"T8","pred":"source","obj":"TEST-DiseaseOrPhenotypicFeature"}]},{"project":"TEST-ChemicalEntity","denotations":[{"id":"T1","span":{"begin":11,"end":33},"obj":"ChemicalEntity"},{"id":"T3","span":{"begin":37,"end":48},"obj":"ChemicalEntity"},{"id":"T5","span":{"begin":124,"end":146},"obj":"ChemicalEntity"},{"id":"T7","span":{"begin":148,"end":152},"obj":"ChemicalEntity"},{"id":"T10","span":{"begin":269,"end":280},"obj":"ChemicalEntity"},{"id":"T12","span":{"begin":297,"end":308},"obj":"ChemicalEntity"},{"id":"T14","span":{"begin":328,"end":332},"obj":"ChemicalEntity"},{"id":"T17","span":{"begin":338,"end":342},"obj":"ChemicalEntity"},{"id":"T20","span":{"begin":395,"end":406},"obj":"ChemicalEntity"},{"id":"T21","span":{"begin":446,"end":457},"obj":"ChemicalEntity"},{"id":"T23","span":{"begin":512,"end":523},"obj":"ChemicalEntity"},{"id":"T25","span":{"begin":946,"end":957},"obj":"ChemicalEntity"},{"id":"T27","span":{"begin":1051,"end":1062},"obj":"ChemicalEntity"},{"id":"T29","span":{"begin":1080,"end":1084},"obj":"ChemicalEntity"},{"id":"T32","span":{"begin":1183,"end":1194},"obj":"ChemicalEntity"},{"id":"T34","span":{"begin":1278,"end":1289},"obj":"ChemicalEntity"},{"id":"T36","span":{"begin":1413,"end":1424},"obj":"ChemicalEntity"},{"id":"T38","span":{"begin":1486,"end":1490},"obj":"ChemicalEntity"},{"id":"T41","span":{"begin":1618,"end":1622},"obj":"ChemicalEntity"},{"id":"T44","span":{"begin":1640,"end":1651},"obj":"ChemicalEntity"}],"attributes":[{"id":"A10","pred":"ID:","subj":"T10","obj":"D000661"},{"id":"A11","pred":"ID:","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A29","pred":"ID:","subj":"T29","obj":"D003687"},{"id":"A30","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A31","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A27","pred":"ID:","subj":"T27","obj":"D000661"},{"id":"A28","pred":"ID:","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A32","pred":"ID:","subj":"T32","obj":"D000661"},{"id":"A33","pred":"ID:","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A7","pred":"ID:","subj":"T7","obj":"D003687"},{"id":"A8","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A9","pred":"ID:","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A12","pred":"ID:","subj":"T12","obj":"D000661"},{"id":"A13","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A41","pred":"ID:","subj":"T41","obj":"D003687"},{"id":"A42","pred":"ID:","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A43","pred":"ID:","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A20","pred":"ID:","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A17","pred":"ID:","subj":"T17","obj":"D003687"},{"id":"A18","pred":"ID:","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A19","pred":"ID:","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A34","pred":"ID:","subj":"T34","obj":"D006220"},{"id":"A35","pred":"ID:","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A25","pred":"ID:","subj":"T25","obj":"D000661"},{"id":"A26","pred":"ID:","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A21","pred":"ID:","subj":"T21","obj":"D001058"},{"id":"A22","pred":"ID:","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_48538"},{"id":"A14","pred":"ID:","subj":"T14","obj":"D003687"},{"id":"A15","pred":"ID:","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A16","pred":"ID:","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A1","pred":"ID:","subj":"T1","obj":"D003687"},{"id":"A2","pred":"ID:","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A5","pred":"ID:","subj":"T5","obj":"D003687"},{"id":"A6","pred":"ID:","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A23","pred":"ID:","subj":"T23","obj":"D006220"},{"id":"A24","pred":"ID:","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A38","pred":"ID:","subj":"T38","obj":"D003687"},{"id":"A39","pred":"ID:","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A40","pred":"ID:","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A3","pred":"ID:","subj":"T3","obj":"D000661"},{"id":"A4","pred":"ID:","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A44","pred":"ID:","subj":"T44","obj":"ChemicalEntity"},{"id":"A36","pred":"ID:","subj":"T36","obj":"D001058"},{"id":"A37","pred":"ID:","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_48538"},{"subj":"T1","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T3","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T5","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T7","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T10","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T12","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T14","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T17","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T20","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T21","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T23","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T25","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T27","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T29","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T32","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T34","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T36","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T38","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T41","pred":"source","obj":"TEST-ChemicalEntity"},{"subj":"T44","pred":"source","obj":"TEST-ChemicalEntity"}]},{"project":"TEST-OrganismTaxon","denotations":[{"id":"T1","span":{"begin":81,"end":85},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":226,"end":230},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":758,"end":764},"obj":"OrganismTaxon"}],"attributes":[{"subj":"T1","pred":"source","obj":"TEST-OrganismTaxon"},{"subj":"T2","pred":"source","obj":"TEST-OrganismTaxon"},{"subj":"T3","pred":"source","obj":"TEST-OrganismTaxon"}]},{"project":"Test-GeneOrGeneProduct","denotations":[{"id":"T1","span":{"begin":148,"end":152},"obj":"GeneOrGeneProduct"},{"id":"T2","span":{"begin":328,"end":332},"obj":"GeneOrGeneProduct"},{"id":"T3","span":{"begin":338,"end":342},"obj":"GeneOrGeneProduct"},{"id":"T4","span":{"begin":890,"end":895},"obj":"GeneOrGeneProduct"},{"id":"T5","span":{"begin":1080,"end":1084},"obj":"GeneOrGeneProduct"},{"id":"T6","span":{"begin":1486,"end":1490},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":1618,"end":1622},"obj":"GeneOrGeneProduct"}],"attributes":[{"subj":"T1","pred":"source","obj":"Test-GeneOrGeneProduct"},{"subj":"T2","pred":"source","obj":"Test-GeneOrGeneProduct"},{"subj":"T3","pred":"source","obj":"Test-GeneOrGeneProduct"},{"subj":"T4","pred":"source","obj":"Test-GeneOrGeneProduct"},{"subj":"T5","pred":"source","obj":"Test-GeneOrGeneProduct"},{"subj":"T6","pred":"source","obj":"Test-GeneOrGeneProduct"},{"subj":"T7","pred":"source","obj":"Test-GeneOrGeneProduct"}]},{"project":"Test-merged","denotations":[{"id":"T8","span":{"begin":1702,"end":1715},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":1532,"end":1541},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1298,"end":1307},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":913,"end":922},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":593,"end":606},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":547,"end":556},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":174,"end":187},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T1","span":{"begin":57,"end":70},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T82927","span":{"begin":758,"end":764},"obj":"OrganismTaxon"},{"id":"T43918","span":{"begin":226,"end":230},"obj":"OrganismTaxon"},{"id":"T86244","span":{"begin":81,"end":85},"obj":"OrganismTaxon"},{"id":"T78333","span":{"begin":890,"end":895},"obj":"GeneOrGeneProduct"},{"id":"T44","span":{"begin":1640,"end":1651},"obj":"ChemicalEntity"},{"id":"T41","span":{"begin":1618,"end":1622},"obj":"ChemicalEntity"},{"id":"T38","span":{"begin":1486,"end":1490},"obj":"ChemicalEntity"},{"id":"T36","span":{"begin":1413,"end":1424},"obj":"ChemicalEntity"},{"id":"T34","span":{"begin":1278,"end":1289},"obj":"ChemicalEntity"},{"id":"T32","span":{"begin":1183,"end":1194},"obj":"ChemicalEntity"},{"id":"T29","span":{"begin":1080,"end":1084},"obj":"ChemicalEntity"},{"id":"T27","span":{"begin":1051,"end":1062},"obj":"ChemicalEntity"},{"id":"T25","span":{"begin":946,"end":957},"obj":"ChemicalEntity"},{"id":"T23","span":{"begin":512,"end":523},"obj":"ChemicalEntity"},{"id":"T21","span":{"begin":446,"end":457},"obj":"ChemicalEntity"},{"id":"T20","span":{"begin":395,"end":406},"obj":"ChemicalEntity"},{"id":"T17","span":{"begin":338,"end":342},"obj":"ChemicalEntity"},{"id":"T14","span":{"begin":328,"end":332},"obj":"ChemicalEntity"},{"id":"T12","span":{"begin":297,"end":308},"obj":"ChemicalEntity"},{"id":"T10","span":{"begin":269,"end":280},"obj":"ChemicalEntity"},{"id":"T65395","span":{"begin":148,"end":152},"obj":"ChemicalEntity"},{"id":"T64866","span":{"begin":124,"end":146},"obj":"ChemicalEntity"},{"id":"T46634","span":{"begin":37,"end":48},"obj":"ChemicalEntity"},{"id":"T84427","span":{"begin":11,"end":33},"obj":"ChemicalEntity"}],"attributes":[{"id":"A31","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A30","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A29","pred":"ID:","subj":"T29","obj":"D003687"},{"id":"A2","pred":"#label","subj":"T2","obj":"D012559"},{"id":"A8","pred":"#label","subj":"T8","obj":"D012559"},{"id":"A28","pred":"ID:","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A27","pred":"ID:","subj":"T27","obj":"D000661"},{"id":"A33","pred":"ID:","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A32","pred":"ID:","subj":"T32","obj":"D000661"},{"id":"A24","pred":"ID:","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A23","pred":"ID:","subj":"T23","obj":"D006220"},{"id":"A43","pred":"ID:","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A42","pred":"ID:","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A41","pred":"ID:","subj":"T41","obj":"D003687"},{"id":"A1","pred":"#label","subj":"T1","obj":"D012559"},{"id":"A82472","pred":"ID:","subj":"T64866","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A89559","pred":"ID:","subj":"T64866","obj":"D003687"},{"id":"A22","pred":"ID:","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_48538"},{"id":"A21","pred":"ID:","subj":"T21","obj":"D001058"},{"id":"A3","pred":"#label","subj":"T3","obj":"D002375"},{"id":"A11","pred":"ID:","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A10","pred":"ID:","subj":"T10","obj":"D000661"},{"id":"A4","pred":"#label","subj":"T4","obj":"D012559"},{"id":"A20","pred":"ID:","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A9","pred":"ID:","subj":"T65395","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A39469","pred":"ID:","subj":"T65395","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A5117","pred":"ID:","subj":"T65395","obj":"D003687"},{"id":"A46194","pred":"ID:","subj":"T46634","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A43753","pred":"ID:","subj":"T46634","obj":"D000661"},{"id":"A6","pred":"#label","subj":"T6","obj":"D002375"},{"id":"A40","pred":"ID:","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A39","pred":"ID:","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A38","pred":"ID:","subj":"T38","obj":"D003687"},{"id":"A85096","pred":"ID:","subj":"T84427","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A19694","pred":"ID:","subj":"T84427","obj":"D003687"},{"id":"A7","pred":"#label","subj":"T7","obj":"D002375"},{"id":"A26","pred":"ID:","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A25","pred":"ID:","subj":"T25","obj":"D000661"},{"id":"A44","pred":"ID:","subj":"T44","obj":"ChemicalEntity"},{"id":"A16","pred":"ID:","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A15","pred":"ID:","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A14","pred":"ID:","subj":"T14","obj":"D003687"},{"id":"A13","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A12","pred":"ID:","subj":"T12","obj":"D000661"},{"id":"A5","pred":"#label","subj":"T5","obj":"D002375"},{"id":"A19","pred":"ID:","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A18","pred":"ID:","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A17","pred":"ID:","subj":"T17","obj":"D003687"},{"id":"A37","pred":"ID:","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_48538"},{"id":"A36","pred":"ID:","subj":"T36","obj":"D001058"},{"id":"A35","pred":"ID:","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A34","pred":"ID:","subj":"T34","obj":"D006220"},{"subj":"T8","pred":"source","obj":"Test-merged"},{"subj":"T7","pred":"source","obj":"Test-merged"},{"subj":"T6","pred":"source","obj":"Test-merged"},{"subj":"T5","pred":"source","obj":"Test-merged"},{"subj":"T4","pred":"source","obj":"Test-merged"},{"subj":"T3","pred":"source","obj":"Test-merged"},{"subj":"T2","pred":"source","obj":"Test-merged"},{"subj":"T1","pred":"source","obj":"Test-merged"},{"subj":"T82927","pred":"source","obj":"Test-merged"},{"subj":"T43918","pred":"source","obj":"Test-merged"},{"subj":"T86244","pred":"source","obj":"Test-merged"},{"subj":"T78333","pred":"source","obj":"Test-merged"},{"subj":"T44","pred":"source","obj":"Test-merged"},{"subj":"T41","pred":"source","obj":"Test-merged"},{"subj":"T38","pred":"source","obj":"Test-merged"},{"subj":"T36","pred":"source","obj":"Test-merged"},{"subj":"T34","pred":"source","obj":"Test-merged"},{"subj":"T32","pred":"source","obj":"Test-merged"},{"subj":"T29","pred":"source","obj":"Test-merged"},{"subj":"T27","pred":"source","obj":"Test-merged"},{"subj":"T25","pred":"source","obj":"Test-merged"},{"subj":"T23","pred":"source","obj":"Test-merged"},{"subj":"T21","pred":"source","obj":"Test-merged"},{"subj":"T20","pred":"source","obj":"Test-merged"},{"subj":"T17","pred":"source","obj":"Test-merged"},{"subj":"T14","pred":"source","obj":"Test-merged"},{"subj":"T12","pred":"source","obj":"Test-merged"},{"subj":"T10","pred":"source","obj":"Test-merged"},{"subj":"T65395","pred":"source","obj":"Test-merged"},{"subj":"T64866","pred":"source","obj":"Test-merged"},{"subj":"T46634","pred":"source","obj":"Test-merged"},{"subj":"T84427","pred":"source","obj":"Test-merged"}]},{"project":"Test-merged-2","denotations":[{"id":"T84427","span":{"begin":11,"end":33},"obj":"ChemicalEntity"},{"id":"T46634","span":{"begin":37,"end":48},"obj":"ChemicalEntity"},{"id":"T64866","span":{"begin":124,"end":146},"obj":"ChemicalEntity"},{"id":"T65395","span":{"begin":148,"end":152},"obj":"ChemicalEntity"},{"id":"T10","span":{"begin":269,"end":280},"obj":"ChemicalEntity"},{"id":"T12","span":{"begin":297,"end":308},"obj":"ChemicalEntity"},{"id":"T14","span":{"begin":328,"end":332},"obj":"ChemicalEntity"},{"id":"T17","span":{"begin":338,"end":342},"obj":"ChemicalEntity"},{"id":"T20","span":{"begin":395,"end":406},"obj":"ChemicalEntity"},{"id":"T21","span":{"begin":446,"end":457},"obj":"ChemicalEntity"},{"id":"T23","span":{"begin":512,"end":523},"obj":"ChemicalEntity"},{"id":"T25","span":{"begin":946,"end":957},"obj":"ChemicalEntity"},{"id":"T27","span":{"begin":1051,"end":1062},"obj":"ChemicalEntity"},{"id":"T29","span":{"begin":1080,"end":1084},"obj":"ChemicalEntity"},{"id":"T32","span":{"begin":1183,"end":1194},"obj":"ChemicalEntity"},{"id":"T34","span":{"begin":1278,"end":1289},"obj":"ChemicalEntity"},{"id":"T36","span":{"begin":1413,"end":1424},"obj":"ChemicalEntity"},{"id":"T38","span":{"begin":1486,"end":1490},"obj":"ChemicalEntity"},{"id":"T41","span":{"begin":1618,"end":1622},"obj":"ChemicalEntity"},{"id":"T44","span":{"begin":1640,"end":1651},"obj":"ChemicalEntity"},{"id":"T10997","span":{"begin":148,"end":152},"obj":"GeneOrGeneProduct"},{"id":"T55644","span":{"begin":328,"end":332},"obj":"GeneOrGeneProduct"},{"id":"T42357","span":{"begin":338,"end":342},"obj":"GeneOrGeneProduct"},{"id":"T78333","span":{"begin":890,"end":895},"obj":"GeneOrGeneProduct"},{"id":"T28171","span":{"begin":1080,"end":1084},"obj":"GeneOrGeneProduct"},{"id":"T14660","span":{"begin":1486,"end":1490},"obj":"GeneOrGeneProduct"},{"id":"T72057","span":{"begin":1618,"end":1622},"obj":"GeneOrGeneProduct"},{"id":"T86244","span":{"begin":81,"end":85},"obj":"OrganismTaxon"},{"id":"T43918","span":{"begin":226,"end":230},"obj":"OrganismTaxon"},{"id":"T82927","span":{"begin":758,"end":764},"obj":"OrganismTaxon"},{"id":"T1","span":{"begin":57,"end":70},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T2","span":{"begin":174,"end":187},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T3","span":{"begin":547,"end":556},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":593,"end":606},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":913,"end":922},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":1298,"end":1307},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":1532,"end":1541},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":1702,"end":1715},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A8","pred":"#label","subj":"T8","obj":"D012559"},{"id":"A2","pred":"#label","subj":"T2","obj":"D012559"},{"id":"A11","pred":"ID:","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A34","pred":"ID:","subj":"T34","obj":"D006220"},{"id":"A35","pred":"ID:","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A1","pred":"#label","subj":"T1","obj":"D012559"},{"id":"A89559","pred":"ID:","subj":"T64866","obj":"D003687"},{"id":"A82472","pred":"ID:","subj":"T64866","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A27","pred":"ID:","subj":"T27","obj":"D000661"},{"id":"A28","pred":"ID:","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A43753","pred":"ID:","subj":"T46634","obj":"D000661"},{"id":"A46194","pred":"ID:","subj":"T46634","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A20","pred":"ID:","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A44","pred":"ID:","subj":"T44","obj":"ChemicalEntity"},{"id":"A17","pred":"ID:","subj":"T17","obj":"D003687"},{"id":"A18","pred":"ID:","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A19","pred":"ID:","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A14","pred":"ID:","subj":"T14","obj":"D003687"},{"id":"A15","pred":"ID:","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A16","pred":"ID:","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A29","pred":"ID:","subj":"T29","obj":"D003687"},{"id":"A30","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A31","pred":"ID:","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A25","pred":"ID:","subj":"T25","obj":"D000661"},{"id":"A26","pred":"ID:","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A5117","pred":"ID:","subj":"T65395","obj":"D003687"},{"id":"A39469","pred":"ID:","subj":"T65395","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A9","pred":"ID:","subj":"T65395","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A5","pred":"#label","subj":"T5","obj":"D002375"},{"id":"A7","pred":"#label","subj":"T7","obj":"D002375"},{"id":"A21","pred":"ID:","subj":"T21","obj":"D001058"},{"id":"A22","pred":"ID:","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_48538"},{"id":"A12","pred":"ID:","subj":"T12","obj":"D000661"},{"id":"A13","pred":"ID:","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A6","pred":"#label","subj":"T6","obj":"D002375"},{"id":"A3","pred":"#label","subj":"T3","obj":"D002375"},{"id":"A23","pred":"ID:","subj":"T23","obj":"D006220"},{"id":"A24","pred":"ID:","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_5613"},{"id":"A32","pred":"ID:","subj":"T32","obj":"D000661"},{"id":"A33","pred":"ID:","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_2679"},{"id":"A41","pred":"ID:","subj":"T41","obj":"D003687"},{"id":"A42","pred":"ID:","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A43","pred":"ID:","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A36","pred":"ID:","subj":"T36","obj":"D001058"},{"id":"A37","pred":"ID:","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_48538"},{"id":"A19694","pred":"ID:","subj":"T84427","obj":"D003687"},{"id":"A85096","pred":"ID:","subj":"T84427","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A4","pred":"#label","subj":"T4","obj":"D012559"},{"id":"A38","pred":"ID:","subj":"T38","obj":"D003687"},{"id":"A39","pred":"ID:","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_89608"},{"id":"A40","pred":"ID:","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A10","pred":"ID:","subj":"T10","obj":"D000661"},{"subj":"T84427","pred":"source","obj":"Test-merged-2"},{"subj":"T46634","pred":"source","obj":"Test-merged-2"},{"subj":"T64866","pred":"source","obj":"Test-merged-2"},{"subj":"T65395","pred":"source","obj":"Test-merged-2"},{"subj":"T10","pred":"source","obj":"Test-merged-2"},{"subj":"T12","pred":"source","obj":"Test-merged-2"},{"subj":"T14","pred":"source","obj":"Test-merged-2"},{"subj":"T17","pred":"source","obj":"Test-merged-2"},{"subj":"T20","pred":"source","obj":"Test-merged-2"},{"subj":"T21","pred":"source","obj":"Test-merged-2"},{"subj":"T23","pred":"source","obj":"Test-merged-2"},{"subj":"T25","pred":"source","obj":"Test-merged-2"},{"subj":"T27","pred":"source","obj":"Test-merged-2"},{"subj":"T29","pred":"source","obj":"Test-merged-2"},{"subj":"T32","pred":"source","obj":"Test-merged-2"},{"subj":"T34","pred":"source","obj":"Test-merged-2"},{"subj":"T36","pred":"source","obj":"Test-merged-2"},{"subj":"T38","pred":"source","obj":"Test-merged-2"},{"subj":"T41","pred":"source","obj":"Test-merged-2"},{"subj":"T44","pred":"source","obj":"Test-merged-2"},{"subj":"T10997","pred":"source","obj":"Test-merged-2"},{"subj":"T55644","pred":"source","obj":"Test-merged-2"},{"subj":"T42357","pred":"source","obj":"Test-merged-2"},{"subj":"T78333","pred":"source","obj":"Test-merged-2"},{"subj":"T28171","pred":"source","obj":"Test-merged-2"},{"subj":"T14660","pred":"source","obj":"Test-merged-2"},{"subj":"T72057","pred":"source","obj":"Test-merged-2"},{"subj":"T86244","pred":"source","obj":"Test-merged-2"},{"subj":"T43918","pred":"source","obj":"Test-merged-2"},{"subj":"T82927","pred":"source","obj":"Test-merged-2"},{"subj":"T1","pred":"source","obj":"Test-merged-2"},{"subj":"T2","pred":"source","obj":"Test-merged-2"},{"subj":"T3","pred":"source","obj":"Test-merged-2"},{"subj":"T4","pred":"source","obj":"Test-merged-2"},{"subj":"T5","pred":"source","obj":"Test-merged-2"},{"subj":"T6","pred":"source","obj":"Test-merged-2"},{"subj":"T7","pred":"source","obj":"Test-merged-2"},{"subj":"T8","pred":"source","obj":"Test-merged-2"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":174,"end":187},"obj":"HP_0100753"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"}]},{"project":"Allie","denotations":[{"id":"SS1_24739405_2_0","span":{"begin":124,"end":146},"obj":"expanded"},{"id":"SS2_24739405_2_0","span":{"begin":148,"end":152},"obj":"abbr"},{"id":"SS1_24739405_5_0","span":{"begin":360,"end":377},"obj":"expanded"},{"id":"SS2_24739405_5_0","span":{"begin":379,"end":381},"obj":"abbr"},{"id":"SS1_24739405_6_0","span":{"begin":469,"end":483},"obj":"expanded"},{"id":"SS2_24739405_6_0","span":{"begin":485,"end":487},"obj":"abbr"}],"relations":[{"id":"AE1_24739405_2_0","pred":"abbreviatedTo","subj":"SS1_24739405_2_0","obj":"SS2_24739405_2_0"},{"id":"AE1_24739405_5_0","pred":"abbreviatedTo","subj":"SS1_24739405_5_0","obj":"SS2_24739405_5_0"},{"id":"AE1_24739405_6_0","pred":"abbreviatedTo","subj":"SS1_24739405_6_0","obj":"SS2_24739405_6_0"}],"attributes":[{"subj":"SS1_24739405_2_0","pred":"source","obj":"Allie"},{"subj":"SS2_24739405_2_0","pred":"source","obj":"Allie"},{"subj":"SS1_24739405_5_0","pred":"source","obj":"Allie"},{"subj":"SS2_24739405_5_0","pred":"source","obj":"Allie"},{"subj":"SS1_24739405_6_0","pred":"source","obj":"Allie"},{"subj":"SS2_24739405_6_0","pred":"source","obj":"Allie"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST-DiseaseOrPhenotypicFeature","color":"#93ecc4","default":true},{"id":"TEST-ChemicalEntity","color":"#ecaa93"},{"id":"TEST-OrganismTaxon","color":"#9395ec"},{"id":"Test-GeneOrGeneProduct","color":"#afec93"},{"id":"Test-merged","color":"#ec93ca"},{"id":"Test-merged-2","color":"#93e4ec"},{"id":"PubmedHPO","color":"#ecda93"},{"id":"Allie","color":"#c093ec"}]}]}}