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PubMed:24671324 JSONTXT

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LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
9821 0-21 DiseaseOrPhenotypicFeature denotes Necrotising fasciitis MESH:D019115
9822 28-38 ChemicalEntity denotes bortezomib MESH:D000069286
9823 43-56 ChemicalEntity denotes dexamethasone MESH:D003907
9824 90-97 OrganismTaxon denotes patient NCBITaxon:9606
9825 101-131 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia MESH:D008258
9826 133-143 ChemicalEntity denotes Bortezomib MESH:D000069286
9827 158-171 ChemicalEntity denotes dexamethasone MESH:D003907
9828 249-269 DiseaseOrPhenotypicFeature denotes bacterial infections MESH:D001424
9829 273-281 OrganismTaxon denotes patients NCBITaxon:9606
9830 294-306 DiseaseOrPhenotypicFeature denotes malignancies MESH:D009369
9831 388-396 OrganismTaxon denotes patients NCBITaxon:9606
9832 432-435 OrganismTaxon denotes man NCBITaxon:9606
9833 441-471 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia MESH:D008258
9834 485-506 DiseaseOrPhenotypicFeature denotes necrotising fasciitis MESH:D019115
9835 515-526 DiseaseOrPhenotypicFeature denotes neutropenia MESH:D009503
9836 564-574 ChemicalEntity denotes bortezomib MESH:D000069286
9837 586-599 ChemicalEntity denotes dexamethasone MESH:D003907
9838 604-613 ChemicalEntity denotes rituximab MESH:D000069283
9839 756-776 DiseaseOrPhenotypicFeature denotes bacterial infections MESH:D001424
9840 788-798 ChemicalEntity denotes bortezomib MESH:D000069286
9841 814-827 ChemicalEntity denotes dexamethasone MESH:D003907
9842 839-847 OrganismTaxon denotes patients NCBITaxon:9606

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 432-435 OrganismTaxon denotes man NCBItxid:9606

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-132 Sentence denotes Necrotising fasciitis after bortezomib and dexamethasone-containing regimen in an elderly patient of Waldenström macroglobulinaemia.
T2 133-307 Sentence denotes Bortezomib and high-dose dexamethasone-containing regimens are considered to be generally tolerable with few severe bacterial infections in patients with B-cell malignancies.
T3 308-397 Sentence denotes However, information is limited concerning the safety of the regimen in elderly patients.
T4 398-614 Sentence denotes We report a case of a 76-year-old man with Waldenström macroglobulinaemia who suffered necrotising fasciitis without neutropenia after the combination treatment with bortezomib, high-dose dexamethasone and rituximab.
T5 615-702 Sentence denotes Despite immediate intravenous antimicrobial therapy, he succumbed 23 h after the onset.
T6 703-905 Sentence denotes Physicians should recognise the possibility of fatal bacterial infections related to bortezomib plus high-dose dexamethasone in elderly patients, and we believe this case warrants further investigation.

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 12-21 DiseaseOrPhenotypicFeature denotes fasciitis 0004830
T2 497-506 DiseaseOrPhenotypicFeature denotes fasciitis 0004830
T3 515-526 DiseaseOrPhenotypicFeature denotes neutropenia 0001475

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 148-152 GeneOrGeneProduct denotes high
T2 223-232 GeneOrGeneProduct denotes tolerable
T3 289-293 GeneOrGeneProduct denotes cell
T4 332-339 GeneOrGeneProduct denotes limited
T5 410-414 GeneOrGeneProduct denotes case
T6 423-427 GeneOrGeneProduct denotes year
T7 576-580 GeneOrGeneProduct denotes high
T8 804-808 GeneOrGeneProduct denotes high
T9 869-873 GeneOrGeneProduct denotes case

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 148-152 GeneOrGeneProduct denotes high
T2 289-293 GeneOrGeneProduct denotes cell
T3 332-339 GeneOrGeneProduct denotes limited
T4 576-580 GeneOrGeneProduct denotes high
T5 804-808 GeneOrGeneProduct denotes high

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 12-21 DiseaseOrPhenotypicFeature denotes fasciitis D005208
T2 101-131 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia D008258
T3 249-269 DiseaseOrPhenotypicFeature denotes bacterial infections D001424
T4 294-306 DiseaseOrPhenotypicFeature denotes malignancies D009369
T5 441-471 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia D008258
T6 497-506 DiseaseOrPhenotypicFeature denotes fasciitis D005208
T7 515-526 DiseaseOrPhenotypicFeature denotes neutropenia D009503
T8 756-776 DiseaseOrPhenotypicFeature denotes bacterial infections D001424

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 12-21 DiseaseOrPhenotypicFeature denotes fasciitis 0004830
T2 101-131 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia 0100280
T3 249-272 DiseaseOrPhenotypicFeature denotes bacterial infections in 0005113
T4 441-471 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia 0100280
T5 497-506 DiseaseOrPhenotypicFeature denotes fasciitis 0004830
T6 515-526 DiseaseOrPhenotypicFeature denotes neutropenia 0001475
T7 668-670 DiseaseOrPhenotypicFeature denotes he 0017319
T8 756-776 DiseaseOrPhenotypicFeature denotes bacterial infections 0005113

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 12-21 DiseaseOrPhenotypicFeature denotes fasciitis D005208
T2 101-131 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia D008258
T3 249-269 DiseaseOrPhenotypicFeature denotes bacterial infections D001424
T4 294-306 DiseaseOrPhenotypicFeature denotes malignancies D009369
T5 441-471 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia D008258
T6 497-506 DiseaseOrPhenotypicFeature denotes fasciitis D005208
T7 515-526 DiseaseOrPhenotypicFeature denotes neutropenia D009503
T8 756-776 DiseaseOrPhenotypicFeature denotes bacterial infections D001424

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 12-21 DiseaseOrPhenotypicFeature denotes fasciitis D005208
T2 101-131 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia D008258
T3 249-269 DiseaseOrPhenotypicFeature denotes bacterial infections D001424
T4 294-306 DiseaseOrPhenotypicFeature denotes malignancies D009369
T5 441-471 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia D008258
T6 497-506 DiseaseOrPhenotypicFeature denotes fasciitis D005208
T7 515-526 DiseaseOrPhenotypicFeature denotes neutropenia D009503
T8 756-776 DiseaseOrPhenotypicFeature denotes bacterial infections D001424

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 28-38 ChemicalEntity denotes bortezomib D000069286|http://purl.obolibrary.org/obo/CHEBI_52717
T3 43-56 ChemicalEntity denotes dexamethasone D003907|http://purl.obolibrary.org/obo/CHEBI_41879
T5 133-143 ChemicalEntity denotes Bortezomib D000069286|http://purl.obolibrary.org/obo/CHEBI_52717
T7 158-171 ChemicalEntity denotes dexamethasone D003907|http://purl.obolibrary.org/obo/CHEBI_41879
T9 564-574 ChemicalEntity denotes bortezomib D000069286|http://purl.obolibrary.org/obo/CHEBI_52717
T11 586-599 ChemicalEntity denotes dexamethasone D003907|http://purl.obolibrary.org/obo/CHEBI_41879
T13 604-613 ChemicalEntity denotes rituximab ChemicalEntity
T14 788-798 ChemicalEntity denotes bortezomib D000069286|http://purl.obolibrary.org/obo/CHEBI_52717
T16 814-827 ChemicalEntity denotes dexamethasone D003907|http://purl.obolibrary.org/obo/CHEBI_41879

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 90-97 OrganismTaxon denotes patient
T2 273-281 OrganismTaxon denotes patients
T3 388-396 OrganismTaxon denotes patients
T4 432-435 OrganismTaxon denotes man
T5 839-847 OrganismTaxon denotes patients

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T16 814-827 ChemicalEntity denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879|D003907
T14 788-798 ChemicalEntity denotes bortezomib http://purl.obolibrary.org/obo/CHEBI_52717|D000069286
T13 604-613 ChemicalEntity denotes rituximab ChemicalEntity
T11 586-599 ChemicalEntity denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879|D003907
T9 564-574 ChemicalEntity denotes bortezomib http://purl.obolibrary.org/obo/CHEBI_52717|D000069286
T7 158-171 ChemicalEntity denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879|D003907
T5 133-143 ChemicalEntity denotes Bortezomib http://purl.obolibrary.org/obo/CHEBI_52717|D000069286
T3 43-56 ChemicalEntity denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879|D003907
T1 28-38 ChemicalEntity denotes bortezomib http://purl.obolibrary.org/obo/CHEBI_52717|D000069286
T8 756-776 DiseaseOrPhenotypicFeature denotes bacterial infections D001424
T62215 515-526 DiseaseOrPhenotypicFeature denotes neutropenia D009503
T6 497-506 DiseaseOrPhenotypicFeature denotes fasciitis D005208
T45991 441-471 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia D008258
T4 294-306 DiseaseOrPhenotypicFeature denotes malignancies D009369
T99350 249-269 DiseaseOrPhenotypicFeature denotes bacterial infections D001424
T2 101-131 DiseaseOrPhenotypicFeature denotes Waldenström macroglobulinaemia D008258
T40593 12-21 DiseaseOrPhenotypicFeature denotes fasciitis D005208
T28207 839-847 OrganismTaxon denotes patients
T81211 432-435 OrganismTaxon denotes man
T67989 388-396 OrganismTaxon denotes patients
T2012 273-281 OrganismTaxon denotes patients
T34751 90-97 OrganismTaxon denotes patient

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 497-506 HP_0100537 denotes fasciitis
T2 515-526 HP_0001875 denotes neutropenia

PubCasesHPO

Id Subject Object Predicate Lexical cue
TI1 12-21 HP:0100537 denotes fasciitis
AB1 497-506 HP:0100537 denotes fasciitis
AB2 515-526 HP:0001875 denotes neutropenia