PubMed:24632949
Annnotations
sonoma2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 0-13 | VAR | denotes | Dysregulation |
| T1 | 17-20 | GENE | denotes | Wnt |
| T2 | 17-40 | GENE | denotes | Wnt inhibitory factor 1 |
| T3 | 42-46 | GENE | denotes | Wif1 |
| T4 | 48-58 | MPA | denotes | expression |
| T5 | 59-67 | REG | denotes | resulted |
| T6 | 68-70 | REG | denotes | in |
| T7 | 80-96 | GENE | denotes | Wnt-β-catenin si |
| T8 | 94-103 | MPA | denotes | signaling |
| T9 | 108-118 | CPA | denotes | cell death |
| T10 | 147-170 | DISEASE | denotes | anorectal malformations |
| T11 | 150-173 | DISEASE | denotes | rectal malformations. I |
| T12 | 357-366 | NEGREG | denotes | Defective |
| T13 | 378-385 | REG | denotes | results |
| T14 | 395-429 | DISEASE | denotes | congenital anorectal malformations |
| T15 | 398-432 | DISEASE | denotes | genital anorectal malformations (A |
| T16 | 431-435 | DISEASE | denotes | ARMs |
| T17 | 602-616 | GENE | denotes | ic Hedgehog (S |
| T18 | 618-621 | GENE | denotes | ). |
| T19 | 646-667 | CPA | denotes | programmed cell death |
| T20 | 779-797 | CPA | denotes | apoptotic endoderm |
| T21 | 810-820 | REG | denotes | associated |
| T22 | 844-854 | MPA | denotes | expression |
| T23 | 858-861 | GENE | denotes | Wnt |
| T24 | 861-884 | GENE | denotes | inhibitory factor 1 (W |
| T25 | 883-887 | GENE | denotes | Wif1 |
| T26 | 886-890 | GENE | denotes | 1), |
| T27 | 902-911 | NEGREG | denotes | inhibitor |
| T28 | 915-938 | MPA | denotes | Wnt-β-catenin signaling |
| T29 | 918-934 | GENE | denotes | -β-catenin signa |
| T30 | 943-957 | GENE | denotes | Wif1(lacZ/lacZ |
| T31 | 949-963 | GENE | denotes | acZ/lacZ) muta |
| T32 | 959-965 | VAR | denotes | mutant |
| T33 | 1009-1013 | GENE | denotes | Wif1 |
| T34 | 1015-1019 | GENE | denotes | cloa |
| T35 | 1036-1045 | NEGREG | denotes | defective |
| T36 | 1071-1087 | DISEASE | denotes | hypospadias-like |
| T37 | 1077-1093 | DISEASE | denotes | adias-like pheno |
| T38 | 1088-1098 | CPA | denotes | phenotypes |
| T39 | 1109-1126 | CPA | denotes | septation defects |
| T40 | 1115-1132 | DISEASE | denotes | ion defects were |
| T41 | 1137-1145 | REG | denotes | observed |
| T42 | 1155-1162 | GENE | denotes | -) muta |
| T43 | 1184-1193 | GENE | denotes | β-catenin |
| T44 | 1190-1202 | GENE | denotes | nin gain-of- |
| T45 | 1194-1210 | POSREG | denotes | gain-of-function |
| T46 | 1212-1215 | POSREG | denotes | GOF |
| T47 | 1217-1224 | VAR | denotes | mutants |
| T48 | 1239-1243 | GENE | denotes | Wif1 |
| T49 | 1248-1251 | GENE | denotes | Shh |
| T50 | 1248-1252 | GENE | denotes | Shh |
| T51 | 1257-1266 | MPA | denotes | expressed |
| T52 | 1257-1260 | GENE | denotes | exp |
| T53 | 1321-1325 | GENE | denotes | Wif1 |
| T54 | 1330-1334 | GENE | denotes | ecto |
| T55 | 1342-1351 | MPA | denotes | expressed |
| T56 | 1370-1380 | REG | denotes | associated |
| T57 | 1407-1416 | CPA | denotes | apoptosis |
| T58 | 1421-1430 | CPA | denotes | septation |
| T59 | 1430-1447 | DISEASE | denotes | defects in Shh(- |
| T60 | 1442-1449 | VAR | denotes | Shh(-/- |
| T61 | 1451-1458 | VAR | denotes | mutants |
| T62 | 1451-1458 | GENE | denotes | mutants |
| T63 | 1473-1488 | CPA | denotes | apoptotic cells |
| T64 | 1503-1510 | NEGREG | denotes | reduced |
| T65 | 1529-1538 | GENE | denotes | β-catenin |
| T66 | 1538-1550 | GENE | denotes | GOF mutant |
| T67 | 1539-1542 | POSREG | denotes | GOF |
| T68 | 1543-1549 | VAR | denotes | mutant |
| T69 | 1565-1577 | NEGREG | denotes | counteracted |
| T70 | 1582-1592 | NEGREG | denotes | inhibitory |
| T71 | 1604-1608 | GENE | denotes | Wif1 |
| T72 | 1616-1620 | GENE | denotes | alto |
| T73 | 1662-1672 | MPA | denotes | expression |
| T74 | 1676-1680 | GENE | denotes | Wif1 |
| T75 | 1688-1692 | GENE | denotes | ical |
| T76 | 1751-1755 | GENE | denotes | Wif1 |
| T77 | 1763-1767 | GENE | denotes | cel |
| T78 | 1769-1778 | CPA | denotes | apoptosis |
| T79 | 1798-1808 | NEGREG | denotes | repressing |
| T80 | 1819-1825 | MPA | denotes | signal |
| T81 | 1821-1833 | GENE | denotes | gnal, which |
| T82 | 1837-1847 | POSREG | denotes | facilitate |
| T83 | 1852-1862 | CPA | denotes | protrusion |
| T84 | 1998-2019 | GENE | denotes | nin signaling axis co |
| T85 | 2017-2028 | REG | denotes | contributes |
| T86 | 2032-2035 | DISEASE | denotes | ARM |
| T87 | 2036-2048 | MPA | denotes | pathogenesis |
| R0 | T0 | T5 | CauseOf | Dysregulation,resulted |
| R1 | T0 | T6 | CauseOf | Dysregulation,in |
| R2 | T0 | T9 | CauseOf | Dysregulation,cell death |
| R3 | T1 | T0 | ThemeOf | Wnt,Dysregulation |
| R4 | T1 | T4 | ThemeOf | Wnt,expression |
| R5 | T3 | T0 | ThemeOf | Wif1,Dysregulation |
| R6 | T3 | T4 | ThemeOf | Wif1,expression |
| R7 | T4 | T0 | ThemeOf | expression,Dysregulation |
| R8 | T4 | T5 | ThemeOf | expression,resulted |
| R9 | T8 | T6 | ThemeOf | signaling,in |
| R10 | T10 | T5 | ThemeOf | anorectal malformations,resulted |
| R11 | T12 | T13 | CauseOf | Defective,results |
| R12 | T14 | T13 | ThemeOf | congenital anorectal malformations,results |
| R13 | T16 | T13 | ThemeOf | ARMs,results |
| R14 | T20 | T21 | ThemeOf | apoptotic endoderm,associated |
| R15 | T22 | T21 | ThemeOf | expression,associated |
| R16 | T22 | T27 | ThemeOf | expression,inhibitor |
| R17 | T23 | T21 | ThemeOf | Wnt,associated |
| R18 | T23 | T22 | ThemeOf | Wnt,expression |
| R19 | T23 | T27 | ThemeOf | Wnt,inhibitor |
| R20 | T25 | T21 | ThemeOf | Wif1,associated |
| R21 | T25 | T22 | ThemeOf | Wif1,expression |
| R22 | T25 | T27 | ThemeOf | Wif1,inhibitor |
| R23 | T28 | T27 | ThemeOf | Wnt-β-catenin signaling,inhibitor |
| R24 | T28 | T21 | ThemeOf | Wnt-β-catenin signaling,associated |
| R25 | T28 | T22 | ThemeOf | Wnt-β-catenin signaling,expression |
| R26 | T30 | T32 | ThemeOf | Wif1(lacZ/lacZ,mutant |
| R27 | T32 | T35 | CauseOf | mutant,defective |
| R28 | T32 | T41 | CauseOf | mutant,observed |
| R29 | T36 | T38 | ThemeOf | hypospadias-like,phenotypes |
| R30 | T38 | T41 | ThemeOf | phenotypes,observed |
| R31 | T39 | T41 | ThemeOf | septation defects,observed |
| R32 | T43 | T47 | ThemeOf | β-catenin,mutants |
| R33 | T45 | T41 | CauseOf | gain-of-function,observed |
| R34 | T46 | T45 | CauseOf | GOF,gain-of-function |
| R35 | T46 | T41 | CauseOf | GOF,observed |
| R36 | T47 | T41 | CauseOf | mutants,observed |
| R37 | T47 | T45 | CauseOf | mutants,gain-of-function |
| R38 | T47 | T46 | CauseOf | mutants,GOF |
| R39 | T48 | T51 | ThemeOf | Wif1,expressed |
| R40 | T48 | T55 | ThemeOf | Wif1,expressed |
| R41 | T49 | T51 | ThemeOf | Shh,expressed |
| R42 | T53 | T51 | ThemeOf | Wif1,expressed |
| R43 | T53 | T55 | ThemeOf | Wif1,expressed |
| R44 | T55 | T56 | ThemeOf | expressed,associated |
| R45 | T58 | T56 | ThemeOf | septation,associated |
| R46 | T65 | T68 | ThemeOf | β-catenin,mutant |
| R47 | T67 | T69 | CauseOf | GOF,counteracted |
| R48 | T68 | T64 | CauseOf | mutant,reduced |
| R49 | T68 | T67 | CauseOf | mutant,GOF |
| R50 | T68 | T69 | CauseOf | mutant,counteracted |
| R51 | T70 | T69 | ThemeOf | inhibitory,counteracted |
| R52 | T74 | T73 | ThemeOf | Wif1,expression |
| R53 | T78 | T79 | ThemeOf | apoptosis,repressing |
| R54 | T80 | T79 | ThemeOf | signal,repressing |
| R55 | T79 | T82 | CauseOf | repressing,facilitate |
| R56 | T83 | T79 | ThemeOf | protrusion,repressing |
| R57 | T83 | T82 | ThemeOf | protrusion,facilitate |
| R58 | T86 | T85 | ThemeOf | ARM,contributes |
| R59 | T86 | T87 | ThemeOf | ARM,pathogenesis |
| R60 | T87 | T85 | ThemeOf | pathogenesis,contributes |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 42-46 | gene:11197 | denotes | Wif1 |
| T1 | 147-170 | disease:C2974527 | denotes | anorectal malformations |
| T2 | 17-40 | gene:11197 | denotes | Wnt inhibitory factor 1 |
| T3 | 147-170 | disease:C2974527 | denotes | anorectal malformations |
| T4 | 1149-1152 | gene:6469 | denotes | Shh |
| T5 | 1071-1082 | disease:C0848558 | denotes | hypospadias |
| T6 | 1009-1013 | gene:11197 | denotes | Wif1 |
| T7 | 1071-1082 | disease:C1691215 | denotes | hypospadias |
| T8 | 1009-1013 | gene:11197 | denotes | Wif1 |
| T9 | 1071-1082 | disease:C0848558 | denotes | hypospadias |
| T10 | 1149-1152 | gene:6469 | denotes | Shh |
| T11 | 1071-1082 | disease:C1691215 | denotes | hypospadias |
| T12 | 943-947 | gene:11197 | denotes | Wif1 |
| T13 | 1071-1082 | disease:C1691215 | denotes | hypospadias |
| T14 | 943-947 | gene:11197 | denotes | Wif1 |
| T15 | 1071-1082 | disease:C0848558 | denotes | hypospadias |
| R1 | T0 | T1 | associated_with | Wif1,anorectal malformations |
| R2 | T2 | T3 | associated_with | Wnt inhibitory factor 1,anorectal malformations |
| R3 | T4 | T5 | associated_with | Shh,hypospadias |
| R4 | T6 | T7 | associated_with | Wif1,hypospadias |
| R5 | T8 | T9 | associated_with | Wif1,hypospadias |
| R6 | T10 | T11 | associated_with | Shh,hypospadias |
| R7 | T12 | T13 | associated_with | Wif1,hypospadias |
| R8 | T14 | T15 | associated_with | Wif1,hypospadias |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 406-429 | HP_0012732 | denotes | anorectal malformations |
| T2 | 1071-1082 | HP_0000047 | denotes | hypospadias |
| T3 | 1109-1126 | HP_0001671 | denotes | septation defects |
| T4 | 1421-1438 | HP_0001671 | denotes | septation defects |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_24632949_0_0 | 17-40 | expanded | denotes | Wnt inhibitory factor 1 |
| SS2_24632949_0_0 | 42-46 | abbr | denotes | Wif1 |
| SS1_24632949_1_0 | 212-228 | expanded | denotes | urorectal septum |
| SS2_24632949_1_0 | 230-233 | abbr | denotes | urs |
| SS1_24632949_1_1 | 278-293 | expanded | denotes | cloaca membrane |
| SS2_24632949_1_1 | 295-297 | abbr | denotes | cm |
| SS1_24632949_2_0 | 406-429 | expanded | denotes | anorectal malformations |
| SS2_24632949_2_0 | 431-435 | abbr | denotes | ARMs |
| SS1_24632949_3_0 | 599-613 | expanded | denotes | Sonic Hedgehog |
| SS2_24632949_3_0 | 615-618 | abbr | denotes | Shh |
| SS1_24632949_5_0 | 858-881 | expanded | denotes | Wnt inhibitory factor 1 |
| SS2_24632949_5_0 | 883-887 | abbr | denotes | Wif1 |
| SS1_24632949_6_0 | 1194-1210 | expanded | denotes | gain-of-function |
| SS2_24632949_6_0 | 1212-1215 | abbr | denotes | GOF |
| AE1_24632949_0_0 | SS1_24632949_0_0 | SS2_24632949_0_0 | abbreviatedTo | Wnt inhibitory factor 1,Wif1 |
| AE1_24632949_1_0 | SS1_24632949_1_0 | SS2_24632949_1_0 | abbreviatedTo | urorectal septum,urs |
| AE1_24632949_1_1 | SS1_24632949_1_1 | SS2_24632949_1_1 | abbreviatedTo | cloaca membrane,cm |
| AE1_24632949_2_0 | SS1_24632949_2_0 | SS2_24632949_2_0 | abbreviatedTo | anorectal malformations,ARMs |
| AE1_24632949_3_0 | SS1_24632949_3_0 | SS2_24632949_3_0 | abbreviatedTo | Sonic Hedgehog,Shh |
| AE1_24632949_5_0 | SS1_24632949_5_0 | SS2_24632949_5_0 | abbreviatedTo | Wnt inhibitory factor 1,Wif1 |
| AE1_24632949_6_0 | SS1_24632949_6_0 | SS2_24632949_6_0 | abbreviatedTo | gain-of-function,GOF |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 24632949-0#17#40#gene11197 | 17-40 | gene11197 | denotes | Wnt inhibitory factor 1 |
| 24632949-0#42#46#gene11197 | 42-46 | gene11197 | denotes | Wif1 |
| 24632949-0#147#170#diseaseC3495676 | 147-170 | diseaseC3495676 | denotes | anorectal malformations |
| 24632949-11#33#36#gene6469 | 1983-1986 | gene6469 | denotes | Shh |
| 24632949-11#82#85#diseaseC3495676 | 2032-2035 | diseaseC3495676 | denotes | ARM |
| 24632949-6#3#7#gene11197 | 943-947 | gene11197 | denotes | Wif1 |
| 24632949-6#69#73#gene11197 | 1009-1013 | gene11197 | denotes | Wif1 |
| 24632949-6#209#212#gene6469 | 1149-1152 | gene6469 | denotes | Shh |
| 24632949-6#131#142#diseaseC0848558 | 1071-1082 | diseaseC0848558 | denotes | hypospadias |
| 24632949-6#131#142#diseaseC1691215 | 1071-1082 | diseaseC1691215 | denotes | hypospadias |
| 24632949-6#131#142#diseaseC0848558 | 1071-1082 | diseaseC0848558 | denotes | hypospadias |
| 24632949-6#131#142#diseaseC1691215 | 1071-1082 | diseaseC1691215 | denotes | hypospadias |
| 24632949-6#131#142#diseaseC0848558 | 1071-1082 | diseaseC0848558 | denotes | hypospadias |
| 24632949-6#131#142#diseaseC1691215 | 1071-1082 | diseaseC1691215 | denotes | hypospadias |
| 17#40#gene11197147#170#diseaseC3495676 | 24632949-0#17#40#gene11197 | 24632949-0#147#170#diseaseC3495676 | associated_with | Wnt inhibitory factor 1,anorectal malformations |
| 42#46#gene11197147#170#diseaseC3495676 | 24632949-0#42#46#gene11197 | 24632949-0#147#170#diseaseC3495676 | associated_with | Wif1,anorectal malformations |
| 33#36#gene646982#85#diseaseC3495676 | 24632949-11#33#36#gene6469 | 24632949-11#82#85#diseaseC3495676 | associated_with | Shh,ARM |
| 3#7#gene11197131#142#diseaseC0848558 | 24632949-6#3#7#gene11197 | 24632949-6#131#142#diseaseC0848558 | associated_with | Wif1,hypospadias |
| 3#7#gene11197131#142#diseaseC1691215 | 24632949-6#3#7#gene11197 | 24632949-6#131#142#diseaseC1691215 | associated_with | Wif1,hypospadias |
| 3#7#gene11197131#142#diseaseC0848558 | 24632949-6#3#7#gene11197 | 24632949-6#131#142#diseaseC0848558 | associated_with | Wif1,hypospadias |
| 3#7#gene11197131#142#diseaseC1691215 | 24632949-6#3#7#gene11197 | 24632949-6#131#142#diseaseC1691215 | associated_with | Wif1,hypospadias |
| 3#7#gene11197131#142#diseaseC0848558 | 24632949-6#3#7#gene11197 | 24632949-6#131#142#diseaseC0848558 | associated_with | Wif1,hypospadias |
| 3#7#gene11197131#142#diseaseC1691215 | 24632949-6#3#7#gene11197 | 24632949-6#131#142#diseaseC1691215 | associated_with | Wif1,hypospadias |
| 69#73#gene11197131#142#diseaseC0848558 | 24632949-6#69#73#gene11197 | 24632949-6#131#142#diseaseC0848558 | associated_with | Wif1,hypospadias |
| 69#73#gene11197131#142#diseaseC1691215 | 24632949-6#69#73#gene11197 | 24632949-6#131#142#diseaseC1691215 | associated_with | Wif1,hypospadias |
| 69#73#gene11197131#142#diseaseC0848558 | 24632949-6#69#73#gene11197 | 24632949-6#131#142#diseaseC0848558 | associated_with | Wif1,hypospadias |
| 69#73#gene11197131#142#diseaseC1691215 | 24632949-6#69#73#gene11197 | 24632949-6#131#142#diseaseC1691215 | associated_with | Wif1,hypospadias |
| 69#73#gene11197131#142#diseaseC0848558 | 24632949-6#69#73#gene11197 | 24632949-6#131#142#diseaseC0848558 | associated_with | Wif1,hypospadias |
| 69#73#gene11197131#142#diseaseC1691215 | 24632949-6#69#73#gene11197 | 24632949-6#131#142#diseaseC1691215 | associated_with | Wif1,hypospadias |
| 209#212#gene6469131#142#diseaseC0848558 | 24632949-6#209#212#gene6469 | 24632949-6#131#142#diseaseC0848558 | associated_with | Shh,hypospadias |
| 209#212#gene6469131#142#diseaseC1691215 | 24632949-6#209#212#gene6469 | 24632949-6#131#142#diseaseC1691215 | associated_with | Shh,hypospadias |
| 209#212#gene6469131#142#diseaseC0848558 | 24632949-6#209#212#gene6469 | 24632949-6#131#142#diseaseC0848558 | associated_with | Shh,hypospadias |
| 209#212#gene6469131#142#diseaseC1691215 | 24632949-6#209#212#gene6469 | 24632949-6#131#142#diseaseC1691215 | associated_with | Shh,hypospadias |
| 209#212#gene6469131#142#diseaseC0848558 | 24632949-6#209#212#gene6469 | 24632949-6#131#142#diseaseC0848558 | associated_with | Shh,hypospadias |
| 209#212#gene6469131#142#diseaseC1691215 | 24632949-6#209#212#gene6469 | 24632949-6#131#142#diseaseC1691215 | associated_with | Shh,hypospadias |
kaiyin_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 1473-1488 | CPA | denotes | apoptotic cells |
| T1 | 1503-1510 | NegReg | denotes | reduced |
| T4 | 1518-1538 | Protein | denotes | endodermal β-catenin |
| T3 | 1539-1542 | PosReg | denotes | GOF |
| T5 | 1543-1549 | Var | denotes | mutant |
| R1 | T4 | T5 | ThemeOf | endodermal β-catenin,mutant |
| R2 | T5 | T3 | CauseOf | mutant,GOF |
| R3 | T3 | T1 | CauseOf | GOF,reduced |
| R4 | T2 | T1 | ThemeOf | apoptotic cells,reduced |
name_no
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 1473-1488 | CPA | denotes | apoptotic cells |
| T1 | 1503-1510 | NegReg | denotes | reduced |
| T4 | 1518-1538 | Protein | denotes | endodermal β-catenin |
| T3 | 1539-1542 | PosReg | denotes | GOF |
| T5 | 1543-1549 | Var | denotes | mutant |
| R1 | T4 | T5 | ThemeOf | endodermal β-catenin,mutant |
| R2 | T5 | T3 | CauseOf | mutant,GOF |
| R3 | T3 | T1 | CauseOf | GOF,reduced |
| R4 | T2 | T1 | ThemeOf | apoptotic cells,reduced |