PubMed:24623901 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/24623901","sourcedb":"PubMed","sourceid":"24623901","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/24623901","text":"Economic benefits of keeping vaccines at ambient temperature during mass vaccination: the case of meningitis A vaccine in Chad.\nOBJECTIVE: To evaluate the potential economic benefits of keeping a meningitis A vaccine at or near ambient temperature for up to 4 days during a mass vaccination campaign.\nMETHODS: During a 10-day mass vaccination campaign against meningitis A in three regions of Chad in 2011, the costs associated with storage and transport of the vaccine in a traditional cold chain system were evaluated. A mathematical model was used to estimate the savings that could have been achieved if the vaccine had been stored at or near ambient temperature--in a \"controlled temperature\" chain--at the peripheral levels of the supply chain system.\nFINDINGS: The cost of the cold chain and associated logistics used in the campaign in Chad was 0.24 United States dollars (US$) per person vaccinated. In the modelled scenario for a controlled temperature chain, however, these costs dropped by 50% and were estimated to be only US$ 0.12 per person vaccinated.\nCONCLUSION: The implementation of a \"controlled temperature\" chain at the most peripheral levels of the supply chain system--assuming no associated loss of vaccine potency, efficacy or safety--could result in major economic benefits and allow vaccine coverage to be extended in low-resource settings.","tracks":[{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":196,"end":206},"obj":"HP_0002858"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubmedHPO","color":"#b893ec","default":true}]}]}}