
PubMed:24558268
Annnotations
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
TextSentencer_T1 | 0-169 | Sentence | denotes | Rapid structural elucidation of polysaccharides employing predicted functions of glycosyltransferases and NMR data: application to the O-antigen of Escherichia coli O59. |
TextSentencer_T2 | 170-377 | Sentence | denotes | A computerized method that uses predicted functions of glycosyltransferases (GTs) in conjunction with unassigned NMR data has been developed for the structural elucidation of bacterial polysaccharides (PSs). |
TextSentencer_T3 | 378-747 | Sentence | denotes | In this approach, information about the action of GTs (consisting of possible sugar residues used as donors and/or acceptors, as well as the anomeric configuration and/or substitution position in the respective glycosidic linkages) is extracted from the Escherichia coli O-antigen database and is submitted, together with the unassigned NMR data, to the CASPER program. |
TextSentencer_T4 | 748-921 | Sentence | denotes | This time saving methodology, which alleviates the need for chemical analysis, was successfully implemented in the structural elucidation of the O-antigen PS of E. coli O59. |
TextSentencer_T5 | 922-1141 | Sentence | denotes | The repeating unit of the O-specific chain was determined using the O-deacylated PS and has a branched structure, namely, →6)[α-d-GalpA3Ac/4Ac-(1 → 3)]-α-d-Manp-(1 → 3)-α-d-Manp-(1 → 3)-β-d-Manp-(1 → 3)-α-d-GlcpNAc-(1→. |
TextSentencer_T6 | 1142-1402 | Sentence | denotes | The identification of the O-acetylation positions was efficiently performed by comparison of the (1)H,(13)C HSQC NMR spectra of the O-deacylated lipopolysaccharide and the lipid-free PS in conjunction with chemical shift predictions made by the CASPER program. |
TextSentencer_T7 | 1403-1557 | Sentence | denotes | The side-chain d-GalpA residue carries one equivalent of O-acetyl groups at the O-3 and O-4 positions distributed in the LPS in a 3:7 ratio, respectively. |
TextSentencer_T8 | 1558-1730 | Sentence | denotes | The presence of O-acetyl groups in the repeating unit of the E. coli O59 PS is consistent with the previously proposed acetyltransferase WclD in the O-antigen gene cluster. |
T1 | 0-169 | Sentence | denotes | Rapid structural elucidation of polysaccharides employing predicted functions of glycosyltransferases and NMR data: application to the O-antigen of Escherichia coli O59. |
T2 | 170-377 | Sentence | denotes | A computerized method that uses predicted functions of glycosyltransferases (GTs) in conjunction with unassigned NMR data has been developed for the structural elucidation of bacterial polysaccharides (PSs). |
T3 | 378-747 | Sentence | denotes | In this approach, information about the action of GTs (consisting of possible sugar residues used as donors and/or acceptors, as well as the anomeric configuration and/or substitution position in the respective glycosidic linkages) is extracted from the Escherichia coli O-antigen database and is submitted, together with the unassigned NMR data, to the CASPER program. |
T4 | 748-921 | Sentence | denotes | This time saving methodology, which alleviates the need for chemical analysis, was successfully implemented in the structural elucidation of the O-antigen PS of E. coli O59. |
T5 | 922-1141 | Sentence | denotes | The repeating unit of the O-specific chain was determined using the O-deacylated PS and has a branched structure, namely, →6)[α-d-GalpA3Ac/4Ac-(1 → 3)]-α-d-Manp-(1 → 3)-α-d-Manp-(1 → 3)-β-d-Manp-(1 → 3)-α-d-GlcpNAc-(1→. |
T6 | 1142-1402 | Sentence | denotes | The identification of the O-acetylation positions was efficiently performed by comparison of the (1)H,(13)C HSQC NMR spectra of the O-deacylated lipopolysaccharide and the lipid-free PS in conjunction with chemical shift predictions made by the CASPER program. |
T7 | 1403-1557 | Sentence | denotes | The side-chain d-GalpA residue carries one equivalent of O-acetyl groups at the O-3 and O-4 positions distributed in the LPS in a 3:7 ratio, respectively. |
T8 | 1558-1730 | Sentence | denotes | The presence of O-acetyl groups in the repeating unit of the E. coli O59 PS is consistent with the previously proposed acetyltransferase WclD in the O-antigen gene cluster. |
T1 | 0-169 | Sentence | denotes | Rapid structural elucidation of polysaccharides employing predicted functions of glycosyltransferases and NMR data: application to the O-antigen of Escherichia coli O59. |
T2 | 170-377 | Sentence | denotes | A computerized method that uses predicted functions of glycosyltransferases (GTs) in conjunction with unassigned NMR data has been developed for the structural elucidation of bacterial polysaccharides (PSs). |
T3 | 378-747 | Sentence | denotes | In this approach, information about the action of GTs (consisting of possible sugar residues used as donors and/or acceptors, as well as the anomeric configuration and/or substitution position in the respective glycosidic linkages) is extracted from the Escherichia coli O-antigen database and is submitted, together with the unassigned NMR data, to the CASPER program. |
T4 | 748-921 | Sentence | denotes | This time saving methodology, which alleviates the need for chemical analysis, was successfully implemented in the structural elucidation of the O-antigen PS of E. coli O59. |
T5 | 922-1141 | Sentence | denotes | The repeating unit of the O-specific chain was determined using the O-deacylated PS and has a branched structure, namely, →6)[α-d-GalpA3Ac/4Ac-(1 → 3)]-α-d-Manp-(1 → 3)-α-d-Manp-(1 → 3)-β-d-Manp-(1 → 3)-α-d-GlcpNAc-(1→. |
T6 | 1142-1402 | Sentence | denotes | The identification of the O-acetylation positions was efficiently performed by comparison of the (1)H,(13)C HSQC NMR spectra of the O-deacylated lipopolysaccharide and the lipid-free PS in conjunction with chemical shift predictions made by the CASPER program. |
T7 | 1403-1557 | Sentence | denotes | The side-chain d-GalpA residue carries one equivalent of O-acetyl groups at the O-3 and O-4 positions distributed in the LPS in a 3:7 ratio, respectively. |
T8 | 1558-1730 | Sentence | denotes | The presence of O-acetyl groups in the repeating unit of the E. coli O59 PS is consistent with the previously proposed acetyltransferase WclD in the O-antigen gene cluster. |
GlycoBiology-PACDB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
_T1 | 148-164 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC002,LEC056,LEC062,LEC069,LEC081,LEC111,LEC133,LEC171,LEC177,LEC187,LEC211,LEC242,LEC252,LEC258,LEC259,LEC260,LEC262,LEC369,LEC377,LEC422,LEC442,LEC448,LEC450,LEC451,LEC454,LEC472,LEC492,LEC620 | denotes | Escherichia coli |
_T2 | 148-164 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC636 | denotes | Escherichia coli |
_T3 | 148-164 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC157,LEC407 | denotes | Escherichia coli |
_T4 | 148-164 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC054,LEC058,LEC073,LEC082,LEC091,LEC103,LEC109,LEC110,LEC123,LEC158,LEC179,LEC198,LEC205,LEC222,LEC223,LEC224,LEC225,LEC232,LEC298,LEC357,LEC378,LEC383,LEC388,LEC389,LEC397,LEC401,LEC410,LEC452 | denotes | Escherichia coli |
_T5 | 148-164 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC244,LEC256,LEC354 | denotes | Escherichia coli |
_T6 | 148-164 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC487 | denotes | Escherichia coli |
_T7 | 148-164 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC295,LEC417 | denotes | Escherichia coli |
_T8 | 148-164 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC243,LEC640 | denotes | Escherichia coli |
_T9 | 148-164 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC754 | denotes | Escherichia coli |
_T10 | 148-168 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC629 | denotes | Escherichia coli O59 |
_T11 | 148-168 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC267,LEC475 | denotes | Escherichia coli O59 |
_T12 | 632-648 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC002,LEC056,LEC062,LEC069,LEC081,LEC111,LEC133,LEC171,LEC177,LEC187,LEC211,LEC242,LEC252,LEC258,LEC259,LEC260,LEC262,LEC369,LEC377,LEC422,LEC442,LEC448,LEC450,LEC451,LEC454,LEC472,LEC492,LEC620 | denotes | Escherichia coli |
_T13 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC629 | denotes | Escherichia coli O |
_T14 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC243,LEC640 | denotes | Escherichia coli O |
_T15 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC267,LEC475 | denotes | Escherichia coli O |
_T16 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC774 | denotes | Escherichia coli O |
_T17 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC328 | denotes | Escherichia coli O |
_T18 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC324 | denotes | Escherichia coli O |
_T19 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC754 | denotes | Escherichia coli O |
_T20 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC487 | denotes | Escherichia coli O |
_T21 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC720 | denotes | Escherichia coli O |
_T22 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC263,LEC665 | denotes | Escherichia coli O |
_T23 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC244,LEC256,LEC354 | denotes | Escherichia coli O |
_T24 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC157,LEC407 | denotes | Escherichia coli O |
_T25 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC054,LEC058,LEC073,LEC082,LEC091,LEC103,LEC109,LEC110,LEC123,LEC158,LEC179,LEC198,LEC205,LEC222,LEC223,LEC224,LEC225,LEC232,LEC298,LEC357,LEC378,LEC383,LEC388,LEC389,LEC397,LEC401,LEC410,LEC452 | denotes | Escherichia coli O |
_T26 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC295,LEC417 | denotes | Escherichia coli O |
_T27 | 632-650 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC636 | denotes | Escherichia coli O |
ICD10
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 255-266 | http://purl.bioontology.org/ontology/ICD10/H10 | denotes | conjunction |
T2 | 1331-1342 | http://purl.bioontology.org/ontology/ICD10/H10 | denotes | conjunction |
T3 | 255-266 | http://purl.bioontology.org/ontology/ICD10/H10.9 | denotes | conjunction |
T4 | 1331-1342 | http://purl.bioontology.org/ontology/ICD10/H10.9 | denotes | conjunction |
GlycoBiology-FMA
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
_T1 | 32-47 | FMAID:196779 | denotes | polysaccharides |
_T2 | 32-47 | FMAID:82785 | denotes | polysaccharides |
_T3 | 32-47 | FMAID:196735 | denotes | polysaccharides |
_T4 | 32-47 | FMAID:82746 | denotes | polysaccharides |
_T5 | 355-370 | FMAID:82746 | denotes | polysaccharides |
_T6 | 355-370 | FMAID:196735 | denotes | polysaccharides |
_T7 | 355-370 | FMAID:196779 | denotes | polysaccharides |
_T8 | 355-370 | FMAID:82785 | denotes | polysaccharides |
_T9 | 456-461 | FMAID:196724 | denotes | sugar |
_T10 | 1016-1024 | FMAID:226028 | denotes | branched |
_T11 | 1016-1024 | FMAID:226027 | denotes | branched |
_T12 | 1287-1305 | FMAID:196779 | denotes | lipopolysaccharide |
_T13 | 1287-1305 | FMAID:82785 | denotes | lipopolysaccharide |
_T14 | 1287-1305 | FMAID:82746 | denotes | lipopolysaccharide |
_T15 | 1287-1305 | FMAID:196735 | denotes | lipopolysaccharide |
_T16 | 1314-1319 | FMAID:67264 | denotes | lipid |
_T17 | 1314-1319 | FMAID:165448 | denotes | lipid |
_T18 | 1717-1721 | FMAID:198663 | denotes | gene |
_T19 | 1717-1729 | FMAID:198017 | denotes | gene cluster |
_T20 | 1717-1729 | FMAID:84082 | denotes | gene cluster |
GlycoBiology-NCBITAXON
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 148-159 | http://purl.bioontology.org/ontology/NCBITAXON/561 | denotes | Escherichia |
T2 | 632-643 | http://purl.bioontology.org/ontology/NCBITAXON/561 | denotes | Escherichia |
T3 | 1469-1475 | http://purl.bioontology.org/ontology/STY/T096 | denotes | groups |
T4 | 1583-1589 | http://purl.bioontology.org/ontology/STY/T096 | denotes | groups |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 301-310 | http://purl.obolibrary.org/obo/GO_0032502 | denotes | developed |
Allie
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
SS1_24558268_1_0 | 225-245 | expanded | denotes | glycosyltransferases |
SS2_24558268_1_0 | 247-250 | abbr | denotes | GTs |
SS1_24558268_1_1 | 355-370 | expanded | denotes | polysaccharides |
SS2_24558268_1_1 | 372-375 | abbr | denotes | PSs |
AE1_24558268_1_0 | SS1_24558268_1_0 | SS2_24558268_1_0 | abbreviatedTo | glycosyltransferases,GTs |
AE1_24558268_1_1 | SS1_24558268_1_1 | SS2_24558268_1_1 | abbreviatedTo | polysaccharides,PSs |
GlyTouCan-IUPAC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
GlycanIUPAC_T1 | 456-461 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
GlycanIUPAC_T2 | 456-461 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
GlycanIUPAC_T3 | 456-461 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
GlycoBiology-Motifs
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 1524-1527 | http://rdf.glycoinfo.org/glycan/G00022MO | denotes | LPS |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 148-164 | OrganismTaxon | denotes | Escherichia coli | 562 |
T2 | 632-648 | OrganismTaxon | denotes | Escherichia coli | 562 |
T3 | 909-916 | OrganismTaxon | denotes | E. coli | 562 |
T4 | 1619-1626 | OrganismTaxon | denotes | E. coli | 562 |