PubMed:24442316 / 1739-2113 JSONTXT

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    Inflammaging

    {"project":"Inflammaging","denotations":[{"id":"T12","span":{"begin":0,"end":374},"obj":"Sentence"},{"id":"T12","span":{"begin":0,"end":374},"obj":"Sentence"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin-sentences

    {"project":"LitCoin-sentences","denotations":[{"id":"T12","span":{"begin":0,"end":374},"obj":"Sentence"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin-entities

    {"project":"LitCoin-entities","denotations":[{"id":"9560","span":{"begin":52,"end":70},"obj":"DiseaseOrPhenotypicFeature"},{"id":"9561","span":{"begin":111,"end":116},"obj":"ChemicalEntity"},{"id":"9562","span":{"begin":167,"end":170},"obj":"ChemicalEntity"},{"id":"9563","span":{"begin":175,"end":178},"obj":"ChemicalEntity"},{"id":"9564","span":{"begin":194,"end":197},"obj":"GeneOrGeneProduct"},{"id":"9565","span":{"begin":202,"end":205},"obj":"GeneOrGeneProduct"},{"id":"9566","span":{"begin":217,"end":224},"obj":"GeneOrGeneProduct"},{"id":"9567","span":{"begin":240,"end":246},"obj":"GeneOrGeneProduct"},{"id":"9568","span":{"begin":248,"end":254},"obj":"GeneOrGeneProduct"},{"id":"9569","span":{"begin":259,"end":262},"obj":"GeneOrGeneProduct"},{"id":"9570","span":{"begin":299,"end":310},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A40","pred":"db_id","subj":"9560","obj":"MESH:D008107"},{"id":"A41","pred":"db_id","subj":"9561","obj":"MESH:D008055"},{"id":"A42","pred":"db_id","subj":"9562","obj":"MESH:D017665"},{"id":"A43","pred":"db_id","subj":"9563","obj":"MESH:D008315"},{"id":"A44","pred":"db_id","subj":"9564","obj":"NCBIGene:20655"},{"id":"A45","pred":"db_id","subj":"9565","obj":"NCBIGene:54486"},{"id":"A46","pred":"db_id","subj":"9566","obj":"NCBIGene:17390"},{"id":"A47","pred":"db_id","subj":"9566","obj":"NCBIGene:17395"},{"id":"A48","pred":"db_id","subj":"9567","obj":"NCBIGene:22329"},{"id":"A49","pred":"db_id","subj":"9568","obj":"NCBIGene:15894"},{"id":"A50","pred":"db_id","subj":"9569","obj":"NCBIGene:22371"},{"id":"A51","pred":"db_id","subj":"9570","obj":"MESH:D008107"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin_Mondo

    {"project":"LitCoin_Mondo","denotations":[{"id":"T6","span":{"begin":103,"end":110},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":304,"end":310},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A6","pred":"mondo_id","subj":"T6","obj":"0002251"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"0021178"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin-GeneOrGeneProduct-v2

    {"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T37","span":{"begin":52,"end":57},"obj":"GeneOrGeneProduct"},{"id":"T38","span":{"begin":86,"end":95},"obj":"GeneOrGeneProduct"},{"id":"T39","span":{"begin":202,"end":205},"obj":"GeneOrGeneProduct"},{"id":"T40","span":{"begin":217,"end":222},"obj":"GeneOrGeneProduct"},{"id":"T41","span":{"begin":240,"end":246},"obj":"GeneOrGeneProduct"},{"id":"T42","span":{"begin":248,"end":254},"obj":"GeneOrGeneProduct"},{"id":"T43","span":{"begin":259,"end":262},"obj":"GeneOrGeneProduct"},{"id":"T44","span":{"begin":315,"end":323},"obj":"GeneOrGeneProduct"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin-GeneOrGeneProduct-v0

    {"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T51","span":{"begin":52,"end":57},"obj":"GeneOrGeneProduct"},{"id":"T52","span":{"begin":86,"end":95},"obj":"GeneOrGeneProduct"},{"id":"T53","span":{"begin":117,"end":129},"obj":"GeneOrGeneProduct"},{"id":"T54","span":{"begin":202,"end":205},"obj":"GeneOrGeneProduct"},{"id":"T55","span":{"begin":217,"end":222},"obj":"GeneOrGeneProduct"},{"id":"T56","span":{"begin":225,"end":235},"obj":"GeneOrGeneProduct"},{"id":"T57","span":{"begin":240,"end":246},"obj":"GeneOrGeneProduct"},{"id":"T58","span":{"begin":248,"end":254},"obj":"GeneOrGeneProduct"},{"id":"T59","span":{"begin":259,"end":262},"obj":"GeneOrGeneProduct"},{"id":"T60","span":{"begin":315,"end":323},"obj":"GeneOrGeneProduct"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin-Disease-MeSH

    {"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T5","span":{"begin":58,"end":70},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":304,"end":310},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A5","pred":"originalLabel","subj":"T5","obj":"D007249"},{"id":"A6","pred":"originalLabel","subj":"T6","obj":"D014947"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin_Mondo_095

    {"project":"LitCoin_Mondo_095","denotations":[{"id":"T14","span":{"begin":52,"end":70},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T15","span":{"begin":194,"end":197},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T17","span":{"begin":304,"end":310},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A14","pred":"mondo_id","subj":"T14","obj":"0002251"},{"id":"A15","pred":"mondo_id","subj":"T15","obj":"0019029"},{"id":"A16","pred":"mondo_id","subj":"T15","obj":"0008428"},{"id":"A17","pred":"mondo_id","subj":"T17","obj":"0021178"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin-GeneOrGeneProduct-v3

    {"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T20","span":{"begin":202,"end":205},"obj":"GeneOrGeneProduct"},{"id":"T21","span":{"begin":217,"end":222},"obj":"GeneOrGeneProduct"},{"id":"T22","span":{"begin":240,"end":246},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":248,"end":254},"obj":"GeneOrGeneProduct"},{"id":"T24","span":{"begin":259,"end":262},"obj":"GeneOrGeneProduct"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin-MeSH-Disease-2

    {"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T7","span":{"begin":58,"end":70},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T9","span":{"begin":304,"end":310},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A7","pred":"ID:","subj":"T7","obj":"DISEASE"},{"id":"A8","pred":"ID:","subj":"T7","obj":"D007249"},{"id":"A9","pred":"ID:","subj":"T9","obj":"D014947"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin-MONDO_bioort2019

    {"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T3","span":{"begin":58,"end":70},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A3","pred":"#label","subj":"T3","obj":"D007249"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin-Chemical-MeSH-CHEBI

    {"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T46","span":{"begin":175,"end":178},"obj":"ChemicalEntity"},{"id":"T47","span":{"begin":194,"end":197},"obj":"ChemicalEntity"},{"id":"T49","span":{"begin":202,"end":205},"obj":"ChemicalEntity"}],"attributes":[{"id":"A46","pred":"ID:","subj":"T46","obj":"http://purl.obolibrary.org/obo/CHEBI_566274"},{"id":"A47","pred":"ID:","subj":"T47","obj":"ChemicalEntity"},{"id":"A48","pred":"ID:","subj":"T47","obj":"D013482"},{"id":"A49","pred":"ID:","subj":"T49","obj":"D005982"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    LitCoin-training-merged

    {"project":"LitCoin-training-merged","denotations":[{"id":"T49","span":{"begin":202,"end":205},"obj":"ChemicalEntity"},{"id":"T47","span":{"begin":194,"end":197},"obj":"ChemicalEntity"},{"id":"T46","span":{"begin":175,"end":178},"obj":"ChemicalEntity"},{"id":"T7438","span":{"begin":259,"end":262},"obj":"GeneOrGeneProduct"},{"id":"T23","span":{"begin":248,"end":254},"obj":"GeneOrGeneProduct"},{"id":"T42925","span":{"begin":240,"end":246},"obj":"GeneOrGeneProduct"},{"id":"T69465","span":{"begin":217,"end":222},"obj":"GeneOrGeneProduct"},{"id":"T3936","span":{"begin":202,"end":205},"obj":"GeneOrGeneProduct"},{"id":"T11473","span":{"begin":58,"end":70},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A49","pred":"ID:","subj":"T49","obj":"D005982"},{"id":"A48","pred":"ID:","subj":"T47","obj":"D013482"},{"id":"A47","pred":"ID:","subj":"T47","obj":"ChemicalEntity"},{"id":"A46","pred":"ID:","subj":"T46","obj":"http://purl.obolibrary.org/obo/CHEBI_566274"},{"id":"A67262","pred":"#label","subj":"T11473","obj":"D007249"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}

    PubmedHPO

    {"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":52,"end":70},"obj":"HP_0012115"}],"text":"Compared to that in the normal control, more severe liver inflammation and hepatocyte apoptosis, worse hepatic lipid peroxidation demonstrated by the increased ASAFR, ·OH and MDA, but decreased SOD and GST, increased MMP-2/9 activities and VCAM-1, ICAM-1 and vWF expressions, which revealed obvious LSEC injury and scaffold structure broken, were shown in the model control."}