PubMed:24278834 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/24278834","sourcedb":"PubMed","sourceid":"24278834","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/24278834","text":"Autism spectrum disorders.\nAutism spectrum disorders (ASDs) are collectively the most commonly diagnosed pediatric neurodevelopmental condition. ASDs include autism, pervasive developmental disorder-not otherwise specified (PDD-NOS), Rett syndrome and Asperger disorder. ASD is characterized by impaired communication and social interaction and may involve developmental delays and seizure disorders. Recent parent-reported diagnosis of ASD in the United States put it at higher levels (1:91) than previously thought, with its diagnosis in boys occurring 4 to 5 times more frequently than in girls (1:58).(1) CDC estimates are currently 1:110;(1) up from 1:150 in 2007.(2) Annual medical expenditures for those affected are generally four to six times greater than for those without ASD.(1) While twin studies demonstrate that genetics play a significant role in ASD, the impact of environment should not be underestimated, given the approximate 20-fold increase in incidence over the last 20 years.(3.)","tracks":[{"project":"Allie","denotations":[{"id":"SS1_24278834_1_0","span":{"begin":27,"end":52},"obj":"expanded"},{"id":"SS2_24278834_1_0","span":{"begin":54,"end":58},"obj":"abbr"},{"id":"SS1_24278834_2_0","span":{"begin":166,"end":222},"obj":"expanded"},{"id":"SS2_24278834_2_0","span":{"begin":224,"end":231},"obj":"abbr"}],"relations":[{"id":"AE1_24278834_1_0","pred":"abbreviatedTo","subj":"SS1_24278834_1_0","obj":"SS2_24278834_1_0"},{"id":"AE1_24278834_2_0","pred":"abbreviatedTo","subj":"SS1_24278834_2_0","obj":"SS2_24278834_2_0"}],"attributes":[{"subj":"SS1_24278834_1_0","pred":"source","obj":"Allie"},{"subj":"SS2_24278834_1_0","pred":"source","obj":"Allie"},{"subj":"SS1_24278834_2_0","pred":"source","obj":"Allie"},{"subj":"SS2_24278834_2_0","pred":"source","obj":"Allie"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":27,"end":33},"obj":"HP_0000717"},{"id":"T2","span":{"begin":158,"end":164},"obj":"HP_0000717"},{"id":"T3","span":{"begin":166,"end":198},"obj":"HP_0000729"},{"id":"T4","span":{"begin":295,"end":340},"obj":"HP_0000735"},{"id":"T5","span":{"begin":322,"end":340},"obj":"HP_0008763"},{"id":"T6","span":{"begin":357,"end":377},"obj":"HP_0001263"},{"id":"T7","span":{"begin":382,"end":389},"obj":"HP_0001250"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"},{"subj":"T3","pred":"source","obj":"PubmedHPO"},{"subj":"T4","pred":"source","obj":"PubmedHPO"},{"subj":"T5","pred":"source","obj":"PubmedHPO"},{"subj":"T6","pred":"source","obj":"PubmedHPO"},{"subj":"T7","pred":"source","obj":"PubmedHPO"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"Allie","color":"#93c2ec","default":true},{"id":"PubmedHPO","color":"#dcec93"}]}]}}