PubMed:24231025 JSONTXT

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":207,"end":225},"obj":"HP_0100543"}],"text":"Cognitive impairment and limited dietary diversity or physical inactivity are conjoint precursors of incident diabetes more so in elderly women than men.\nOBJECTIVES: To establish whether elderly people with impaired cognition are at greater risk for the de-velopment of type 2 diabetes.\nDESIGN: Prospective population-based cohort study.\nSETTING: The El-derly Nutrition and Health Survey in Taiwan (NAHSIT Elderly).\nPARTICIPANTS: One thousand and four hundred ninety-three diabetes-free people \u003e=65 years were followed for incident diabetes in relation to cognitive status for up to 8 years.\nMEASUREMENTS: The association between cognitive impairment and diabetes incidence was analyzed with Cox proportional hazards models with exclusion of people who had diabetes within one year of cognitive function assessments.\nRESULTS: Cognitively-impaired women, but not men, had increased diabetes incidence density (DID). Age, gender, ethnicity and personal behavior adjusted hazard ratios (HR) and 95% confidence intervals (CI) for type 2 diabetes with normal cognition as referent were 2.43 (95% CI: 1.27-4.63) for women and 1.55 (95% CI: 0.48-5.07) for men. These gender differences and the HR significances remained with adjustments for age, ethnicity, financial status, dietary quality as a dietary diversity score, physical function, physical activity, fasting glucose, indices of body composition, body mass index, waist circumference, mid-arm muscle circumference, perceived and mental health status. There were extensive significant interactions with the covariates in women.\nCONCLUSION: Cognitive impairment in later life is associated with greater risk of type 2 diabetes in women and considerable potential risk enhancement."}

{"project":"Allie","denotations":[{"id":"SS1_24231025_12_0","span":{"begin":881,"end":907},"obj":"expanded"},{"id":"SS2_24231025_12_0","span":{"begin":909,"end":912},"obj":"abbr"},{"id":"SS1_24231025_13_0","span":{"begin":969,"end":982},"obj":"expanded"},{"id":"SS2_24231025_13_0","span":{"begin":984,"end":986},"obj":"abbr"},{"id":"SS1_24231025_13_1","span":{"begin":996,"end":1016},"obj":"expanded"},{"id":"SS2_24231025_13_1","span":{"begin":1018,"end":1020},"obj":"abbr"}],"relations":[{"id":"AE1_24231025_12_0","pred":"abbreviatedTo","subj":"SS1_24231025_12_0","obj":"SS2_24231025_12_0"},{"id":"AE1_24231025_13_0","pred":"abbreviatedTo","subj":"SS1_24231025_13_0","obj":"SS2_24231025_13_0"},{"id":"AE1_24231025_13_1","pred":"abbreviatedTo","subj":"SS1_24231025_13_1","obj":"SS2_24231025_13_1"}],"text":"Cognitive impairment and limited dietary diversity or physical inactivity are conjoint precursors of incident diabetes more so in elderly women than men.\nOBJECTIVES: To establish whether elderly people with impaired cognition are at greater risk for the de-velopment of type 2 diabetes.\nDESIGN: Prospective population-based cohort study.\nSETTING: The El-derly Nutrition and Health Survey in Taiwan (NAHSIT Elderly).\nPARTICIPANTS: One thousand and four hundred ninety-three diabetes-free people \u003e=65 years were followed for incident diabetes in relation to cognitive status for up to 8 years.\nMEASUREMENTS: The association between cognitive impairment and diabetes incidence was analyzed with Cox proportional hazards models with exclusion of people who had diabetes within one year of cognitive function assessments.\nRESULTS: Cognitively-impaired women, but not men, had increased diabetes incidence density (DID). Age, gender, ethnicity and personal behavior adjusted hazard ratios (HR) and 95% confidence intervals (CI) for type 2 diabetes with normal cognition as referent were 2.43 (95% CI: 1.27-4.63) for women and 1.55 (95% CI: 0.48-5.07) for men. These gender differences and the HR significances remained with adjustments for age, ethnicity, financial status, dietary quality as a dietary diversity score, physical function, physical activity, fasting glucose, indices of body composition, body mass index, waist circumference, mid-arm muscle circumference, perceived and mental health status. There were extensive significant interactions with the covariates in women.\nCONCLUSION: Cognitive impairment in later life is associated with greater risk of type 2 diabetes in women and considerable potential risk enhancement."}