| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-25 |
Sentence |
denotes |
"A" motor neuron disease. |
| TextSentencer_T2 |
26-37 |
Sentence |
denotes |
IMPORTANCE: |
| TextSentencer_T3 |
38-193 |
Sentence |
denotes |
Allgrove syndrome is a rare autosomal recessive disorder characterised by achalasia, alacrima, adrenal insufficiency, autonomic dysfunction and amyotrophy. |
| TextSentencer_T4 |
194-292 |
Sentence |
denotes |
The syndrome has been described in childhood and adult presentation, as in our case, is very rare. |
| TextSentencer_T5 |
293-380 |
Sentence |
denotes |
There is a considerable delay in diagnosis due to lack of awareness about the syndrome. |
| TextSentencer_T6 |
381-394 |
Sentence |
denotes |
OBSERVATIONS: |
| TextSentencer_T7 |
395-534 |
Sentence |
denotes |
We report a single case of a 36 year old man who was initially diagnosed and treated for achalasia cardia in our institute 14 years before. |
| TextSentencer_T8 |
535-617 |
Sentence |
denotes |
After 8 years he presented again with weakness and wasting predominantly distally. |
| TextSentencer_T9 |
618-684 |
Sentence |
denotes |
He had tongue fasciculations, brisk reflexes and extensor plantar. |
| TextSentencer_T10 |
685-781 |
Sentence |
denotes |
After supportive electrophysiological studies he was diagnosed as Amyotrophic lateral sclerosis. |
| TextSentencer_T11 |
782-895 |
Sentence |
denotes |
After 5 years he presented with generalised fatigue without any significant worsening of his neurological status. |
| TextSentencer_T12 |
896-977 |
Sentence |
denotes |
On reevaluation he had alacrimia, autonomic dysfunction and mild ACTH resistance. |
| TextSentencer_T13 |
978-1004 |
Sentence |
denotes |
CONCLUSIONS AND RELEVANCE: |
| TextSentencer_T14 |
1005-1194 |
Sentence |
denotes |
Allgrove syndrome may be an underdiagnosed cause of multisystem neurological disease due to the heterogeneous clinical presentation as well as for ignorance of clinician about the syndrome. |
| TextSentencer_T15 |
1195-1319 |
Sentence |
denotes |
Based on our case, we also believe that there does exist a subgroup of patients who follow a less severe and chronic course. |
| TextSentencer_T16 |
1320-1427 |
Sentence |
denotes |
Recognition of syndrome allows for treatment of autonomic dysfunction, adrenal insufficiency and dysphagia. |
| T1 |
0-25 |
Sentence |
denotes |
"A" motor neuron disease. |
| T2 |
26-37 |
Sentence |
denotes |
IMPORTANCE: |
| T3 |
38-193 |
Sentence |
denotes |
Allgrove syndrome is a rare autosomal recessive disorder characterised by achalasia, alacrima, adrenal insufficiency, autonomic dysfunction and amyotrophy. |
| T4 |
194-292 |
Sentence |
denotes |
The syndrome has been described in childhood and adult presentation, as in our case, is very rare. |
| T5 |
293-380 |
Sentence |
denotes |
There is a considerable delay in diagnosis due to lack of awareness about the syndrome. |
| T6 |
381-394 |
Sentence |
denotes |
OBSERVATIONS: |
| T7 |
395-534 |
Sentence |
denotes |
We report a single case of a 36 year old man who was initially diagnosed and treated for achalasia cardia in our institute 14 years before. |
| T8 |
535-617 |
Sentence |
denotes |
After 8 years he presented again with weakness and wasting predominantly distally. |
| T9 |
618-684 |
Sentence |
denotes |
He had tongue fasciculations, brisk reflexes and extensor plantar. |
| T10 |
685-781 |
Sentence |
denotes |
After supportive electrophysiological studies he was diagnosed as Amyotrophic lateral sclerosis. |
| T11 |
782-895 |
Sentence |
denotes |
After 5 years he presented with generalised fatigue without any significant worsening of his neurological status. |
| T12 |
896-977 |
Sentence |
denotes |
On reevaluation he had alacrimia, autonomic dysfunction and mild ACTH resistance. |
| T13 |
978-1004 |
Sentence |
denotes |
CONCLUSIONS AND RELEVANCE: |
| T14 |
1005-1194 |
Sentence |
denotes |
Allgrove syndrome may be an underdiagnosed cause of multisystem neurological disease due to the heterogeneous clinical presentation as well as for ignorance of clinician about the syndrome. |
| T15 |
1195-1319 |
Sentence |
denotes |
Based on our case, we also believe that there does exist a subgroup of patients who follow a less severe and chronic course. |
| T16 |
1320-1427 |
Sentence |
denotes |
Recognition of syndrome allows for treatment of autonomic dysfunction, adrenal insufficiency and dysphagia. |