PubMed:24014866
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/24014866","sourcedb":"PubMed","sourceid":"24014866","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/24014866","text":"The rare sugar D-allose acts as a triggering molecule of rice defence via ROS generation.\nOnly D-allose, among various rare monosaccharides tested, induced resistance to Xanthomonas oryzae pv. oryzae in susceptible rice leaves with defence responses: reactive oxygen species, lesion mimic formation, and PR-protein gene expression. These responses were suppressed by ascorbic acid or diphenylene iodonium. Transgenic rice plants overexpressing OsrbohC, encoding NADPH oxidase, were enhanced in sensitivity to D-allose. D-Allose-mediated defence responses were suppressed by the presence of a hexokinase inhibitor. 6-Deoxy-D-allose, a structural derivative of D-allose unable to be phosphorylated, did not confer resistance. Transgenic rice plants expressing Escherichia coli AlsK encoding D-allose kinase to increase D-allose 6-phosphate synthesis were more sensitive to D-allose, but E. coli AlsI encoding D-allose 6-phosphate isomerase expression to decrease D-allose 6-phosphate reduced sensitivity. A D-glucose 6-phosphate dehydrogenase-defective mutant was also less sensitive, and OsG6PDH1 complementation restored full sensitivity. These results reveal that a monosaccharide, D-allose, induces rice resistance to X. oryzae pv. oryzae by activating NADPH oxidase through the activity of D-glucose 6-phosphate dehydrogenase, initiated by hexokinase-mediated conversion of D-allose to D-allose 6-phosphate, and treatment with D-allose might prove to be useful for reducing disease development in rice.","tracks":[{"project":"pqqtest_sentence","denotations":[{"id":"M_0","span":{"begin":907,"end":948},"obj":"cand:TO:0000314-phosphoglycerate mutase content"},{"id":"M_1","span":{"begin":907,"end":948},"obj":"cand:TO:0000331-sucrose phosphate synthase activity trait"},{"id":"M_2","span":{"begin":907,"end":948},"obj":"cand:TO:0005008-acetolactate synthase inhibitor sensitivity"},{"id":"M_3","span":{"begin":907,"end":948},"obj":"cand:funRiceGene:129-protein kinase"},{"id":"M_4","span":{"begin":907,"end":948},"obj":"cand:funRiceGene:320-starch 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