PubMed:2400807 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T0	461-476	gene:9699	denotes	nuclear protein
T1	427-430	disease:C0023473	denotes	CML
T2	461-476	gene:7936	denotes	nuclear protein
T3	427-430	disease:C0023473	denotes	CML
R1	T0	T1	associated_with	nuclear protein,CML
R2	T2	T3	associated_with	nuclear protein,CML

Id	Subject	Object	Predicate	Lexical cue
T1	142-170	HP_0005506	denotes	chronic myelogenous leukemia
T2	162-170	HP_0001909	denotes	leukemia

Id	Subject	Object	Predicate	Lexical cue
T1	19-35	protein	denotes	nuclear proteins
T2	142-182	cell_type	denotes	chronic myelogenous leukemia (CML) cells
T3	275-291	protein	denotes	nuclear proteins
T4	375-384	cell_type	denotes	CML cells
T5	388-397	protein	denotes	IFN-alpha
T6	427-451	protein	denotes	CML cytoplasmic proteins
T7	461-490	protein	denotes	nuclear protein-DNA complexes
T8	535-544	protein	denotes	IFN-alpha
T9	584-587	protein	denotes	IFN
T10	638-667	protein	denotes	nuclear protein-DNA complexes
T11	707-716	protein	denotes	IFN-alpha
T12	804-820	protein	denotes	nuclear proteins

Id	Subject	Object	Predicate	Lexical cue
2400807-1#0#19#gene8548	108-127	gene8548	denotes	Cytoplasmic protein
2400807-1#34#62#diseaseC0023473	142-170	diseaseC0023473	denotes	chronic myelogenous leukemia
2400807-1#64#67#diseaseC0023473	172-175	diseaseC0023473	denotes	CML
0#19#gene854834#62#diseaseC0023473	2400807-1#0#19#gene8548	2400807-1#34#62#diseaseC0023473	associated_with	Cytoplasmic protein,chronic myelogenous leukemia
0#19#gene854864#67#diseaseC0023473	2400807-1#0#19#gene8548	2400807-1#64#67#diseaseC0023473	associated_with	Cytoplasmic protein,CML

Id	Subject	Object	Predicate	Lexical cue
C1	19-35	NP	denotes	nuclear proteins
C3	142-182	NP	denotes	chronic myelogenous leukemia (CML) cells
C2	108-182	NP	denotes	Cytoplasmic protein extracts from chronic myelogenous leukemia (CML) cells
C4	193-204	NP	denotes	an activity
C5	205-209	NP	denotes	that
C6	375-384	NP	denotes	CML cells
C7	388-397	NP	denotes	IFN-alpha
C8	423-451	NP	denotes	the CML cytoplasmic proteins
C9	455-490	NP	denotes	these nuclear protein-DNA complexes
C10	535-544	NP	denotes	IFN-alpha
C11	638-667	NP	denotes	nuclear protein-DNA complexes
C12	707-716	NP	denotes	IFN-alpha
C13	720-723	NP	denotes	CML
C14	741-750	NP	denotes	a pathway
C15	751-755	NP	denotes	that
C16	804-820	NP	denotes	nuclear proteins
R1	C5	C4	coref-relat	that,an activity
R2	C6	C3	coref-ident	CML cells,chronic myelogenous leukemia (CML) cells
R3	C8	C2	coref-ident	the CML cytoplasmic proteins,Cytoplasmic protein extracts from chronic myelogenous leukemia (CML) cells
R4	C10	C7	coref-ident	IFN-alpha,IFN-alpha
R5	C11	C9	coref-ident	nuclear protein-DNA complexes,these nuclear protein-DNA complexes
R6	C12	C10	coref-ident	IFN-alpha,IFN-alpha
R7	C13	C6	coref-ident	CML,CML cells
R8	C15	C14	coref-relat	that,a pathway
R9	C16	C1	coref-ident	nuclear proteins,nuclear proteins

Id	Subject	Object	Predicate	Lexical cue
S1	0-107	Sentence	denotes	Interferon affects nuclear proteins in cells of clinically sensitive chronic myelogenous leukemia patients.
S2	108-362	Sentence	denotes	Cytoplasmic protein extracts from chronic myelogenous leukemia (CML) cells contained an activity that altered the electrophoretic mobility of complexes formed between nuclear proteins and the transcriptional enhancers of interferon (IFN)-inducible genes.
S3	363-491	Sentence	denotes	Exposure of CML cells to IFN-alpha diminished the effect of the CML cytoplasmic proteins on these nuclear protein-DNA complexes.
S4	492-668	Sentence	denotes	The presence of clinical responsiveness to IFN-alpha correlated with the sensitivity to the IFN-induced change in the electrophoretic mobility of nuclear protein-DNA complexes.
S5	669-821	Sentence	denotes	These data suggest that the action of IFN-alpha in CML may be linked to a pathway that can result in posttranslational modification of nuclear proteins.

Id	Subject	Object	Predicate	Lexical cue
T1	19-35	protein_family_or_group	denotes	nuclear proteins
T2	48-68	multi_cell	denotes	clinically sensitive
T3	69-97	other_name	denotes	chronic myelogenous leukemia
T4	108-136	cell_component	denotes	Cytoplasmic protein extracts
T5	142-170	other_name	denotes	chronic myelogenous leukemia
T6	172-175	other_name	denotes	CML
T7	275-291	protein_family_or_group	denotes	nuclear proteins
T8	375-384	cell_type	denotes	CML cells
T9	388-397	protein_molecule	denotes	IFN-alpha
T10	427-451	protein_family_or_group	denotes	CML cytoplasmic proteins
T11	461-490	protein_complex	denotes	nuclear protein-DNA complexes
T12	535-544	protein_molecule	denotes	IFN-alpha
T13	584-587	protein_family_or_group	denotes	IFN
T14	610-634	other_name	denotes	electrophoretic mobility
T15	638-667	protein_complex	denotes	nuclear protein-DNA complexes
T16	707-716	protein_molecule	denotes	IFN-alpha
T17	720-723	other_name	denotes	CML
T18	804-820	protein_family_or_group	denotes	nuclear proteins