PubMed:23999868
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 24-27 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T3 | 51-54 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T5 | 97-100 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T7 | 147-150 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T9 | 156-167 | Glycan_Motif | denotes | sialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
| T10 | 251-254 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T12 | 292-310 | Glycan_Motif | denotes | galactosylceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T13 | 312-318 | Glycan_Motif | denotes | GalCer | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T14 | 343-346 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T16 | 384-400 | Glycan_Motif | denotes | lactosylceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G74621DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G20420WT |
| T19 | 402-408 | Glycan_Motif | denotes | LacCer | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW |
| T20 | 432-435 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T22 | 494-497 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T24 | 545-548 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T26 | 627-630 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T28 | 679-682 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T30 | 709-712 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T32 | 760-766 | Glycan_Motif | denotes | LacCer | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW |
| T33 | 768-774 | Glycan_Motif | denotes | GalCer | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T34 | 780-783 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T36 | 796-799 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T38 | 866-872 | Glycan_Motif | denotes | LacCer | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW |
| T39 | 877-880 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T41 | 914-920 | Glycan_Motif | denotes | GalCer | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T42 | 946-949 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T44 | 982-985 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T46 | 986-989 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T48 | 1000-1003 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T50 | 1151-1157 | Glycan_Motif | denotes | LacCer | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW |
| T51 | 1220-1226 | Glycan_Motif | denotes | LacCer | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW |
| T52 | 1240-1243 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T54 | 1250-1256 | Glycan_Motif | denotes | GalCer | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T55 | 1379-1382 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T57 | 1435-1441 | Glycan_Motif | denotes | LacCer | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW |
| T58 | 1446-1452 | Glycan_Motif | denotes | GalCer | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T59 | 1457-1460 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T61 | 1496-1499 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T63 | 1566-1569 | Glycan_Motif | denotes | GM4 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G77824XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G30207PZ |
| T65 | 1629-1632 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 227-232 | http://purl.obolibrary.org/obo/MAT_0000098 | denotes | brain |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-130 | Sentence | denotes | Expression machinery of GM4: the excess amounts of GM3/GM4S synthase (ST3GAL5) are necessary for GM4 synthesis in mammalian cells. |
| TextSentencer_T2 | 131-250 | Sentence | denotes | The ganglioside GM4 is a sialic acid-containing glycosphingolipid mainly expressed in mammalian brain and erythrocytes. |
| TextSentencer_T3 | 251-410 | Sentence | denotes | GM4 is synthesized by the sialylation of galactosylceramide (GalCer), while the ganglioside GM3 is synthesized by the sialylation of lactosylceramide (LacCer). |
| TextSentencer_T4 | 411-585 | Sentence | denotes | Recently, the enzyme GM3 synthase was found to be responsible for the synthesis of GM4 in vitro and in vivo, yet the mechanism behind GM4 expression in cells remains unclear. |
| TextSentencer_T5 | 586-693 | Sentence | denotes | In this study, we attempted to establish GM4-reconstituted cells to reveal the regulation of GM4 synthesis. |
| TextSentencer_T6 | 694-784 | Sentence | denotes | Interestingly, GM4 was not detected in RPMI 1846 cells expressing LacCer, GalCer, and GM3. |
| TextSentencer_T7 | 785-945 | Sentence | denotes | Similarly, GM4 was not detected in CHO-K1 cells, even when such cells expressing LacCer and GM3 were stably transfected with the GalCer synthase (GalCerS) gene. |
| TextSentencer_T8 | 946-1086 | Sentence | denotes | GM4 became detectable only when the GM3/GM4 synthase (GM3/GM4S, ST3GAL5) gene was overexpressed in either RPMI 1846 or CHO-K1/GalCerS cells. |
| TextSentencer_T9 | 1087-1249 | Sentence | denotes | A mutant of the B16 melanoma cell line, GM-95, lacks GlcCer and LacCer, due to an absence of GlcCer synthase, but carries endogenous LacCer synthase and GM3/GM4S. |
| TextSentencer_T10 | 1250-1510 | Sentence | denotes | GalCer became detectable after transfection of GalCerS into GM95 cells, but the GM95/GalCerS reconstituted cells did not express GM4, indicating that competition between the substrates LacCer and GalCer for GM3/GM4S does not cause the failure of GM4 synthesis. |
| TextSentencer_T11 | 1511-1633 | Sentence | denotes | These results suggest that the expression machinery of GM4 under physiological conditions is independent from that of GM3. |
| T1 | 0-130 | Sentence | denotes | Expression machinery of GM4: the excess amounts of GM3/GM4S synthase (ST3GAL5) are necessary for GM4 synthesis in mammalian cells. |
| T2 | 131-250 | Sentence | denotes | The ganglioside GM4 is a sialic acid-containing glycosphingolipid mainly expressed in mammalian brain and erythrocytes. |
| T3 | 251-410 | Sentence | denotes | GM4 is synthesized by the sialylation of galactosylceramide (GalCer), while the ganglioside GM3 is synthesized by the sialylation of lactosylceramide (LacCer). |
| T4 | 411-585 | Sentence | denotes | Recently, the enzyme GM3 synthase was found to be responsible for the synthesis of GM4 in vitro and in vivo, yet the mechanism behind GM4 expression in cells remains unclear. |
| T5 | 586-693 | Sentence | denotes | In this study, we attempted to establish GM4-reconstituted cells to reveal the regulation of GM4 synthesis. |
| T6 | 694-784 | Sentence | denotes | Interestingly, GM4 was not detected in RPMI 1846 cells expressing LacCer, GalCer, and GM3. |
| T7 | 785-945 | Sentence | denotes | Similarly, GM4 was not detected in CHO-K1 cells, even when such cells expressing LacCer and GM3 were stably transfected with the GalCer synthase (GalCerS) gene. |
| T8 | 946-1086 | Sentence | denotes | GM4 became detectable only when the GM3/GM4 synthase (GM3/GM4S, ST3GAL5) gene was overexpressed in either RPMI 1846 or CHO-K1/GalCerS cells. |
| T9 | 1087-1249 | Sentence | denotes | A mutant of the B16 melanoma cell line, GM-95, lacks GlcCer and LacCer, due to an absence of GlcCer synthase, but carries endogenous LacCer synthase and GM3/GM4S. |
| T10 | 1250-1510 | Sentence | denotes | GalCer became detectable after transfection of GalCerS into GM95 cells, but the GM95/GalCerS reconstituted cells did not express GM4, indicating that competition between the substrates LacCer and GalCer for GM3/GM4S does not cause the failure of GM4 synthesis. |
| T11 | 1511-1633 | Sentence | denotes | These results suggest that the expression machinery of GM4 under physiological conditions is independent from that of GM3. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 24-27 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T2 | 24-27 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T3 | 51-54 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T4 | 51-54 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T5 | 97-100 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T6 | 97-100 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T7 | 147-150 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T8 | 147-150 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T9 | 156-167 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T10 | 251-254 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T11 | 251-254 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T12 | 292-310 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactosylceramide |
| T13 | 343-346 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T14 | 343-346 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T15 | 384-400 | https://glytoucan.org/Structures/Glycans/G20420WT | denotes | lactosylceramide |
| T16 | 384-400 | https://glytoucan.org/Structures/Glycans/G74621DY | denotes | lactosylceramide |
| T17 | 384-400 | https://glytoucan.org/Structures/Glycans/G84224TW | denotes | lactosylceramide |
| T18 | 432-435 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T19 | 432-435 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T20 | 494-497 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T21 | 494-497 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T22 | 545-548 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T23 | 545-548 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T24 | 627-630 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T25 | 627-630 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T26 | 679-682 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T27 | 679-682 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T28 | 709-712 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T29 | 709-712 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T30 | 780-783 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T31 | 780-783 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T32 | 796-799 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T33 | 796-799 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T34 | 877-880 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T35 | 877-880 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T36 | 946-949 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T37 | 946-949 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T38 | 982-985 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T39 | 982-985 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T40 | 986-989 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T41 | 986-989 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T42 | 1000-1003 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T43 | 1000-1003 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T44 | 1240-1243 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T45 | 1240-1243 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T46 | 1379-1382 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T47 | 1379-1382 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T48 | 1457-1460 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T49 | 1457-1460 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T50 | 1496-1499 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T51 | 1496-1499 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T52 | 1566-1569 | https://glytoucan.org/Structures/Glycans/G30207PZ | denotes | GM4 |
| T53 | 1566-1569 | https://glytoucan.org/Structures/Glycans/G77824XV | denotes | GM4 |
| T54 | 1629-1632 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T55 | 1629-1632 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 24-27 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T2 | 97-100 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T3 | 147-150 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T4 | 251-254 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T5 | 292-310 | http://www.glycoepitope.jp/epitopes/EP0074 | denotes | galactosylceramide |
| T6 | 312-318 | http://www.glycoepitope.jp/epitopes/EP0074 | denotes | GalCer |
| T7 | 384-400 | http://www.glycoepitope.jp/epitopes/EP0078 | denotes | lactosylceramide |
| T8 | 402-408 | http://www.glycoepitope.jp/epitopes/EP0078 | denotes | LacCer |
| T9 | 494-497 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T10 | 545-548 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T11 | 627-630 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T12 | 679-682 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T13 | 709-712 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T14 | 760-766 | http://www.glycoepitope.jp/epitopes/EP0078 | denotes | LacCer |
| T15 | 768-774 | http://www.glycoepitope.jp/epitopes/EP0074 | denotes | GalCer |
| T16 | 796-799 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T17 | 866-872 | http://www.glycoepitope.jp/epitopes/EP0078 | denotes | LacCer |
| T18 | 914-920 | http://www.glycoepitope.jp/epitopes/EP0074 | denotes | GalCer |
| T19 | 946-949 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T20 | 986-989 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T21 | 1151-1157 | http://www.glycoepitope.jp/epitopes/EP0078 | denotes | LacCer |
| T22 | 1220-1226 | http://www.glycoepitope.jp/epitopes/EP0078 | denotes | LacCer |
| T23 | 1250-1256 | http://www.glycoepitope.jp/epitopes/EP0074 | denotes | GalCer |
| T24 | 1379-1382 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T25 | 1435-1441 | http://www.glycoepitope.jp/epitopes/EP0078 | denotes | LacCer |
| T26 | 1446-1452 | http://www.glycoepitope.jp/epitopes/EP0074 | denotes | GalCer |
| T27 | 1496-1499 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
| T28 | 1566-1569 | http://www.glycoepitope.jp/epitopes/EP0055 | denotes | GM4 |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_23999868_2_0 | 292-310 | expanded | denotes | galactosylceramide |
| SS2_23999868_2_0 | 312-318 | abbr | denotes | GalCer |
| SS1_23999868_2_1 | 294-310 | expanded | denotes | lactosylceramide |
| SS2_23999868_2_1 | 402-408 | abbr | denotes | LacCer |
| SS1_23999868_6_0 | 914-929 | expanded | denotes | GalCer synthase |
| SS2_23999868_6_0 | 931-938 | abbr | denotes | GalCerS |
| AE1_23999868_2_0 | SS1_23999868_2_0 | SS2_23999868_2_0 | abbreviatedTo | galactosylceramide,GalCer |
| AE1_23999868_2_1 | SS1_23999868_2_1 | SS2_23999868_2_1 | abbreviatedTo | lactosylceramide,LacCer |
| AE1_23999868_6_0 | SS1_23999868_6_0 | SS2_23999868_6_0 | abbreviatedTo | GalCer synthase,GalCerS |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 237-249 | HP_0001901 | denotes | erythrocytes |
| T2 | 1107-1115 | HP_0002861 | denotes | melanoma |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 1107-1115 | Disease | denotes | melanoma | http://purl.obolibrary.org/obo/MONDO_0005105 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 24-27 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T2 | 51-54 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T3 | 97-100 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T4 | 147-150 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T5 | 251-254 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T6 | 292-310 | Glycan | denotes | galactosylceramide | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T7 | 312-318 | Glycan | denotes | GalCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T8 | 343-346 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T9 | 384-400 | Glycan | denotes | lactosylceramide | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T10 | 402-408 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T11 | 432-435 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T12 | 494-497 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T13 | 545-548 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T14 | 627-630 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T15 | 679-682 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T16 | 709-712 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T17 | 760-766 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T18 | 768-774 | Glycan | denotes | GalCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T19 | 780-783 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T20 | 796-799 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T21 | 866-872 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T22 | 877-880 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T23 | 914-920 | Glycan | denotes | GalCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T24 | 946-949 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T25 | 982-985 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T26 | 986-989 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T27 | 1000-1003 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T28 | 1151-1157 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T29 | 1220-1226 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T30 | 1240-1243 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T31 | 1250-1256 | Glycan | denotes | GalCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T32 | 1379-1382 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T33 | 1435-1441 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T34 | 1446-1452 | Glycan | denotes | GalCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T35 | 1457-1460 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T36 | 1496-1499 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T37 | 1566-1569 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T38 | 1629-1632 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 227-232 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 1107-1115 | Phenotype | denotes | melanoma | HP:0002861 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 24-27 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T2 | 51-54 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T3 | 97-100 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T4 | 147-150 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T5 | 251-254 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T6 | 292-310 | Glycan | denotes | galactosylceramide | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T7 | 312-318 | Glycan | denotes | GalCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T8 | 343-346 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T9 | 384-400 | Glycan | denotes | lactosylceramide | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T10 | 402-408 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T11 | 432-435 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T12 | 494-497 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T13 | 545-548 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T14 | 627-630 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T15 | 679-682 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T16 | 709-712 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T17 | 760-766 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T18 | 768-774 | Glycan | denotes | GalCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T19 | 780-783 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T20 | 796-799 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T21 | 866-872 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T22 | 877-880 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T23 | 914-920 | Glycan | denotes | GalCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T24 | 946-949 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T25 | 982-985 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T26 | 986-989 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T27 | 1000-1003 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T28 | 1151-1157 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T29 | 1220-1226 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T30 | 1240-1243 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T31 | 1250-1256 | Glycan | denotes | GalCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T32 | 1379-1382 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T33 | 1435-1441 | Glycan | denotes | LacCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW |
| T34 | 1446-1452 | Glycan | denotes | GalCer | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T35 | 1457-1460 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T36 | 1496-1499 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T37 | 1566-1569 | Glycan | denotes | GM4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G30207PZ |
| T38 | 1629-1632 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 24-27 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T2 | 97-100 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T3 | 147-150 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T4 | 251-254 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T5 | 292-310 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | galactosylceramide | http://www.glycoepitope.jp/epitopes/EP0074 |
| T6 | 312-318 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GalCer | http://www.glycoepitope.jp/epitopes/EP0074 |
| T7 | 384-400 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | lactosylceramide | http://www.glycoepitope.jp/epitopes/EP0078 |
| T8 | 402-408 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T9 | 494-497 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T10 | 545-548 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T11 | 627-630 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T12 | 679-682 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T13 | 709-712 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T14 | 760-766 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T15 | 768-774 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GalCer | http://www.glycoepitope.jp/epitopes/EP0074 |
| T16 | 796-799 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T17 | 866-872 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T18 | 914-920 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GalCer | http://www.glycoepitope.jp/epitopes/EP0074 |
| T19 | 946-949 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T20 | 986-989 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T21 | 1151-1157 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T22 | 1220-1226 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T23 | 1250-1256 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GalCer | http://www.glycoepitope.jp/epitopes/EP0074 |
| T24 | 1379-1382 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T25 | 1435-1441 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T26 | 1446-1452 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GalCer | http://www.glycoepitope.jp/epitopes/EP0074 |
| T27 | 1496-1499 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T28 | 1566-1569 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 1107-1115 | Phenotype | denotes | melanoma | HP:0002861 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 237-249 | Cell | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL:0000232 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 227-232 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
| T2 | 237-249 | Body_part | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL_0000232 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 1107-1115 | Disease | denotes | melanoma | MONDO:0005105 |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 24-27 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T2 | 97-100 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T3 | 147-150 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T4 | 251-254 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T5 | 292-310 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | galactosylceramide | http://www.glycoepitope.jp/epitopes/EP0074 |
| T6 | 312-318 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GalCer | http://www.glycoepitope.jp/epitopes/EP0074 |
| T7 | 384-400 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | lactosylceramide | http://www.glycoepitope.jp/epitopes/EP0078 |
| T8 | 402-408 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T9 | 494-497 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T10 | 545-548 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T11 | 627-630 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T12 | 679-682 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T13 | 709-712 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T14 | 760-766 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T15 | 768-774 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GalCer | http://www.glycoepitope.jp/epitopes/EP0074 |
| T16 | 796-799 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T17 | 866-872 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T18 | 914-920 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GalCer | http://www.glycoepitope.jp/epitopes/EP0074 |
| T19 | 946-949 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T20 | 986-989 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T21 | 1151-1157 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T22 | 1220-1226 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T23 | 1250-1256 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GalCer | http://www.glycoepitope.jp/epitopes/EP0074 |
| T24 | 1379-1382 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T25 | 1435-1441 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | LacCer | http://www.glycoepitope.jp/epitopes/EP0078 |
| T26 | 1446-1452 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GalCer | http://www.glycoepitope.jp/epitopes/EP0074 |
| T27 | 1496-1499 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
| T28 | 1566-1569 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM4 | http://www.glycoepitope.jp/epitopes/EP0055 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 114-123 | Organism | denotes | mammalian | 40674 |
| T2 | 217-226 | Organism | denotes | mammalian | 40674 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-130 | Sentence | denotes | Expression machinery of GM4: the excess amounts of GM3/GM4S synthase (ST3GAL5) are necessary for GM4 synthesis in mammalian cells. |
| T2 | 131-250 | Sentence | denotes | The ganglioside GM4 is a sialic acid-containing glycosphingolipid mainly expressed in mammalian brain and erythrocytes. |
| T3 | 251-410 | Sentence | denotes | GM4 is synthesized by the sialylation of galactosylceramide (GalCer), while the ganglioside GM3 is synthesized by the sialylation of lactosylceramide (LacCer). |
| T4 | 411-585 | Sentence | denotes | Recently, the enzyme GM3 synthase was found to be responsible for the synthesis of GM4 in vitro and in vivo, yet the mechanism behind GM4 expression in cells remains unclear. |
| T5 | 586-693 | Sentence | denotes | In this study, we attempted to establish GM4-reconstituted cells to reveal the regulation of GM4 synthesis. |
| T6 | 694-784 | Sentence | denotes | Interestingly, GM4 was not detected in RPMI 1846 cells expressing LacCer, GalCer, and GM3. |
| T7 | 785-945 | Sentence | denotes | Similarly, GM4 was not detected in CHO-K1 cells, even when such cells expressing LacCer and GM3 were stably transfected with the GalCer synthase (GalCerS) gene. |
| T8 | 946-1086 | Sentence | denotes | GM4 became detectable only when the GM3/GM4 synthase (GM3/GM4S, ST3GAL5) gene was overexpressed in either RPMI 1846 or CHO-K1/GalCerS cells. |
| T9 | 1087-1249 | Sentence | denotes | A mutant of the B16 melanoma cell line, GM-95, lacks GlcCer and LacCer, due to an absence of GlcCer synthase, but carries endogenous LacCer synthase and GM3/GM4S. |
| T10 | 1250-1510 | Sentence | denotes | GalCer became detectable after transfection of GalCerS into GM95 cells, but the GM95/GalCerS reconstituted cells did not express GM4, indicating that competition between the substrates LacCer and GalCer for GM3/GM4S does not cause the failure of GM4 synthesis. |
| T11 | 1511-1633 | Sentence | denotes | These results suggest that the expression machinery of GM4 under physiological conditions is independent from that of GM3. |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 227-232 | Body_part | denotes | brain | FMA:50801 |
| T2 | 237-249 | Body_part | denotes | erythrocytes | FMA:62845 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 227-232 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 227-232 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
| T3 | 237-249 | Body_part | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL_0000232 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 237-249 | Cell | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL:0000232 |