PubMed:23973 JSONTXT

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":172,"end":182},"obj":"HP_0000716"}],"text":"Oxypertine in combination with imipramine: a controlled trial.\nA method for the controlled assessment of two agents for possible interaction in the treatment of endogenous depression is described. This consisted of dose-ranging the supplementary agent (oxypertine 30 mg and 60 mg daily or matching placebo) during Week 2 to Week 6 having established all patients on a therapeutic dose of imipramine during Week 1. The reported enhancement of imipramine by oxypertine was not confirmed."}