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PubMed:23949582 JSONTXT

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LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
9301 26-36 ChemicalEntity denotes ifosfamide MESH:D007069
9302 38-43 ChemicalEntity denotes mesna MESH:D015080
9303 81-87 OrganismTaxon denotes rabbit NCBITaxon:9986
9304 140-150 ChemicalEntity denotes Ifosfamide MESH:D007069
9305 152-155 ChemicalEntity denotes IFO MESH:D007069
9306 163-190 ChemicalEntity denotes alkylating nitrogen mustard MESH:D008357
9307 297-308 DiseaseOrPhenotypicFeature denotes hemorrhagic MESH:D006470
9308 309-317 DiseaseOrPhenotypicFeature denotes cystitis MESH:D003556
9309 339-342 ChemicalEntity denotes IFO MESH:D007069
9310 397-429 ChemicalEntity denotes sodium 2-sulfanylethanesulfonate MESH:D015080
9311 431-436 ChemicalEntity denotes Mesna MESH:D015080
9312 479-482 ChemicalEntity denotes IFO MESH:D007069
9313 487-492 ChemicalEntity denotes Mesna MESH:D015080
9314 526-532 OrganismTaxon denotes rabbit NCBITaxon:9986
9315 716-721 ChemicalEntity denotes Mesna MESH:D015080
9316 752-755 ChemicalEntity denotes IFO MESH:D007069
9317 840-843 ChemicalEntity denotes IFO MESH:D007069
9318 916-921 ChemicalEntity denotes Mesna MESH:D015080
9319 1002-1005 ChemicalEntity denotes IFO MESH:D007069
9320 1059-1064 ChemicalEntity denotes Mesna MESH:D015080
9321 1087-1090 ChemicalEntity denotes IFO MESH:D007069
9322 1093-1105 DiseaseOrPhenotypicFeature denotes genotoxicity MESH:D030342

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 81-87 OrganismTaxon denotes rabbit NCBItxid:9986

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-139 Sentence denotes The cytogenetic action of ifosfamide, mesna, and their combination on peripheral rabbit lymphocytes: an in vivo/in vitro cytogenetic study.
T2 140-233 Sentence denotes Ifosfamide (IFO) is an alkylating nitrogen mustard, administrated as an antineoplasmic agent.
T3 234-318 Sentence denotes It is characterized by its intense urotoxic action, leading to hemorrhagic cystitis.
T4 319-478 Sentence denotes This side effect of IFO raises the requirement for the co-administration with sodium 2-sulfanylethanesulfonate (Mesna) aiming to avoid or minimize this effect.
T5 479-592 Sentence denotes IFO and Mesna were administrated separately on rabbit's lymphocytes in vivo, which were later developed in vitro.
T6 593-715 Sentence denotes Cytogenetic markers for sister chromatid exchanges (SCEs), proliferation rate index (PRI) and Mitotic Index were recorded.
T7 716-866 Sentence denotes Mesna's action, in conjunction with IFO reduces the frequency of SCEs, in comparison with the SCEs recordings obtained when IFO is administered alone.
T8 867-1058 Sentence denotes In addition to this, when high concentrations of Mesna were administered alone significant reductions of the PRI were noted, than with IFO acting at the same concentration on the lymphocytes.
T9 1059-1224 Sentence denotes Mesna significantly reduces IFO's genotoxicity, while when administered in high concentrations it acts in an inhibitory fashion on the cytostatic action of the drug.

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 297-317 DiseaseOrPhenotypicFeature denotes hemorrhagic cystitis 0000496
T2 309-317 DiseaseOrPhenotypicFeature denotes cystitis 0006032
T3 735-746 DiseaseOrPhenotypicFeature denotes conjunction 0003799

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 81-87 GeneOrGeneProduct denotes rabbit
T2 88-99 GeneOrGeneProduct denotes lymphocytes
T3 183-190 GeneOrGeneProduct denotes mustard
T4 324-328 GeneOrGeneProduct denotes side
T5 343-349 GeneOrGeneProduct denotes raises
T6 512-522 GeneOrGeneProduct denotes separately
T7 526-534 GeneOrGeneProduct denotes rabbit's
T8 535-546 GeneOrGeneProduct denotes lymphocytes
T9 567-572 GeneOrGeneProduct denotes later
T10 756-763 GeneOrGeneProduct denotes reduces
T11 768-777 GeneOrGeneProduct denotes frequency
T12 893-897 GeneOrGeneProduct denotes high
T13 1006-1012 GeneOrGeneProduct denotes acting
T14 1046-1057 GeneOrGeneProduct denotes lymphocytes
T15 1079-1086 GeneOrGeneProduct denotes reduces
T16 1134-1138 GeneOrGeneProduct denotes high
T17 1157-1161 GeneOrGeneProduct denotes acts

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 81-87 GeneOrGeneProduct denotes rabbit
T2 88-99 GeneOrGeneProduct denotes lymphocytes
T3 183-190 GeneOrGeneProduct denotes mustard
T4 324-328 GeneOrGeneProduct denotes side
T5 535-546 GeneOrGeneProduct denotes lymphocytes
T6 768-777 GeneOrGeneProduct denotes frequency
T7 893-897 GeneOrGeneProduct denotes high
T8 1046-1057 GeneOrGeneProduct denotes lymphocytes
T9 1134-1138 GeneOrGeneProduct denotes high

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 297-308 DiseaseOrPhenotypicFeature denotes hemorrhagic D006470
T2 309-317 DiseaseOrPhenotypicFeature denotes cystitis D003556

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 81-87 GeneOrGeneProduct denotes rabbit
T2 183-190 GeneOrGeneProduct denotes mustard

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 297-317 DiseaseOrPhenotypicFeature denotes hemorrhagic cystitis 0000496

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 309-317 DiseaseOrPhenotypicFeature denotes cystitis D003556
T2 1093-1105 DiseaseOrPhenotypicFeature denotes genotoxicity DISEASE

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 309-317 DiseaseOrPhenotypicFeature denotes cystitis D003556
T2 1093-1105 DiseaseOrPhenotypicFeature denotes genotoxicity DISEASE

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 81-87 OrganismTaxon denotes rabbit
T2 526-534 OrganismTaxon denotes rabbit's

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 26-36 ChemicalEntity denotes ifosfamide D007069|http://purl.obolibrary.org/obo/CHEBI_5864
T3 38-43 ChemicalEntity denotes mesna D015080|ChemicalEntity
T5 140-150 ChemicalEntity denotes Ifosfamide D007069|http://purl.obolibrary.org/obo/CHEBI_5864
T7 152-155 ChemicalEntity denotes IFO ChemicalEntity|D007069
T9 174-190 ChemicalEntity denotes nitrogen mustard D008466|http://purl.obolibrary.org/obo/CHEBI_37598|http://purl.obolibrary.org/obo/CHEBI_28925
T12 339-342 ChemicalEntity denotes IFO ChemicalEntity|D007069
T14 397-403 ChemicalEntity denotes sodium D012964|http://purl.obolibrary.org/obo/CHEBI_26708
T16 404-429 ChemicalEntity denotes 2-sulfanylethanesulfonate http://purl.obolibrary.org/obo/CHEBI_58319
T17 431-436 ChemicalEntity denotes Mesna http://purl.obolibrary.org/obo/CHEBI_31824|http://purl.obolibrary.org/obo/CHEBI_17905|ChemicalEntity
T20 479-482 ChemicalEntity denotes IFO ChemicalEntity|D007069
T22 487-492 ChemicalEntity denotes Mesna http://purl.obolibrary.org/obo/CHEBI_31824|http://purl.obolibrary.org/obo/CHEBI_17905|ChemicalEntity
T25 752-755 ChemicalEntity denotes IFO ChemicalEntity|D007069
T27 840-843 ChemicalEntity denotes IFO ChemicalEntity|D007069
T29 916-921 ChemicalEntity denotes Mesna http://purl.obolibrary.org/obo/CHEBI_31824|http://purl.obolibrary.org/obo/CHEBI_17905|ChemicalEntity
T32 1002-1005 ChemicalEntity denotes IFO ChemicalEntity|D007069
T34 1059-1064 ChemicalEntity denotes Mesna http://purl.obolibrary.org/obo/CHEBI_31824|http://purl.obolibrary.org/obo/CHEBI_17905|ChemicalEntity

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T34 1059-1064 ChemicalEntity denotes Mesna ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_17905|http://purl.obolibrary.org/obo/CHEBI_31824
T32 1002-1005 ChemicalEntity denotes IFO D007069|ChemicalEntity
T29 916-921 ChemicalEntity denotes Mesna ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_17905|http://purl.obolibrary.org/obo/CHEBI_31824
T27 840-843 ChemicalEntity denotes IFO ChemicalEntity|D007069
T25 752-755 ChemicalEntity denotes IFO D007069|ChemicalEntity
T22 487-492 ChemicalEntity denotes Mesna ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_17905|http://purl.obolibrary.org/obo/CHEBI_31824
T20 479-482 ChemicalEntity denotes IFO D007069|ChemicalEntity
T17 431-436 ChemicalEntity denotes Mesna ChemicalEntity|http://purl.obolibrary.org/obo/CHEBI_17905|http://purl.obolibrary.org/obo/CHEBI_31824
T16 404-429 ChemicalEntity denotes 2-sulfanylethanesulfonate http://purl.obolibrary.org/obo/CHEBI_58319
T14 397-403 ChemicalEntity denotes sodium http://purl.obolibrary.org/obo/CHEBI_26708|D012964
T12 339-342 ChemicalEntity denotes IFO D007069|ChemicalEntity
T9 174-190 ChemicalEntity denotes nitrogen mustard http://purl.obolibrary.org/obo/CHEBI_28925|http://purl.obolibrary.org/obo/CHEBI_37598|D008466
T7 152-155 ChemicalEntity denotes IFO D007069|ChemicalEntity
T5 140-150 ChemicalEntity denotes Ifosfamide http://purl.obolibrary.org/obo/CHEBI_5864|D007069
T3 38-43 ChemicalEntity denotes mesna ChemicalEntity|D015080
T1 26-36 ChemicalEntity denotes ifosfamide http://purl.obolibrary.org/obo/CHEBI_5864|D007069
T2 183-190 GeneOrGeneProduct denotes mustard
T38102 81-87 GeneOrGeneProduct denotes rabbit
T59953 1093-1105 DiseaseOrPhenotypicFeature denotes genotoxicity DISEASE
T86233 309-317 DiseaseOrPhenotypicFeature denotes cystitis D003556
T28627 526-534 OrganismTaxon denotes rabbit's
T35386 81-87 OrganismTaxon denotes rabbit