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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-41 Sentence denotes Red blood cell clearance in inflammation.
T2 42-50 Sentence denotes SUMMARY:
T3 51-124 Sentence denotes Anemia is a frequently encountered problem in the critically ill patient.
T4 125-404 Sentence denotes The inability to compensate for anemia includes several mechanisms, collectively referred to as anemia of inflammation: reduced production of erythropoietin, impaired bone marrow response to erythropoietin, reduced iron availability, and increased red blood cell (RBC) clearance.
T5 405-476 Sentence denotes This review focuses on mechanisms of RBC clearance during inflammation.
T6 477-744 Sentence denotes We state that phosphatidylserine (PS) expression in inflammation is mainly enhanced due to an increase in ceramide, caused by an increase in sphingomyelinase activity due to either platelet activating factor, tumor necrosis factor-α, or direct production by bacteria.
T7 745-830 Sentence denotes Phagocytosis of RBCs during inflammation is mediated via RBC membrane protein band 3.
T8 831-1007 Sentence denotes Reduced deformability of RBCs seems an important feature in inflammation, also mediated by band 3 as well as by nitric oxide, reactive oxygen species, and sialic acid residues.
T9 1008-1245 Sentence denotes Also, adherence of RBCs to the endothelium is increased during inflammation, most likely due to increased expression of endothelial adhesion molecules as well as PS on the RBC membrane, in combination with decreased capillary blood flow.
T10 1246-1424 Sentence denotes Thereby, clearance of RBCs during inflammation shows similarities to clearance of senescent RBCs, but also has distinct entities, including increased adhesion to the endothelium.
T1 0-41 Sentence denotes Red blood cell clearance in inflammation.
T2 42-50 Sentence denotes SUMMARY:
T3 51-124 Sentence denotes Anemia is a frequently encountered problem in the critically ill patient.
T4 125-404 Sentence denotes The inability to compensate for anemia includes several mechanisms, collectively referred to as anemia of inflammation: reduced production of erythropoietin, impaired bone marrow response to erythropoietin, reduced iron availability, and increased red blood cell (RBC) clearance.
T5 405-476 Sentence denotes This review focuses on mechanisms of RBC clearance during inflammation.
T6 477-744 Sentence denotes We state that phosphatidylserine (PS) expression in inflammation is mainly enhanced due to an increase in ceramide, caused by an increase in sphingomyelinase activity due to either platelet activating factor, tumor necrosis factor-α, or direct production by bacteria.
T7 745-830 Sentence denotes Phagocytosis of RBCs during inflammation is mediated via RBC membrane protein band 3.
T8 831-1007 Sentence denotes Reduced deformability of RBCs seems an important feature in inflammation, also mediated by band 3 as well as by nitric oxide, reactive oxygen species, and sialic acid residues.
T9 1008-1245 Sentence denotes Also, adherence of RBCs to the endothelium is increased during inflammation, most likely due to increased expression of endothelial adhesion molecules as well as PS on the RBC membrane, in combination with decreased capillary blood flow.
T10 1246-1424 Sentence denotes Thereby, clearance of RBCs during inflammation shows similarities to clearance of senescent RBCs, but also has distinct entities, including increased adhesion to the endothelium.

Allie

Id Subject Object Predicate Lexical cue
SS1_23801928_3_0 373-387 expanded denotes red blood cell
SS2_23801928_3_0 389-392 abbr denotes RBC
SS1_23801928_5_0 491-509 expanded denotes phosphatidylserine
SS2_23801928_5_0 511-513 abbr denotes PS
AE1_23801928_3_0 SS1_23801928_3_0 SS2_23801928_3_0 abbreviatedTo red blood cell,RBC
AE1_23801928_5_0 SS1_23801928_5_0 SS2_23801928_5_0 abbreviatedTo phosphatidylserine,PS

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 51-57 HP_0001903 denotes Anemia
T2 157-163 HP_0001903 denotes anemia
T3 221-227 HP_0001903 denotes anemia
T4 686-691 HP_0002664 denotes tumor