PubMed:23760764
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/23760764","sourcedb":"PubMed","sourceid":"23760764","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/23760764","text":"Intensive medical weight loss or laparoscopic adjustable gastric banding in the treatment of mild to moderate obesity: long-term follow-up of a prospective randomised trial.\nBACKGROUND: Proven short-term effectiveness of obesity therapy should be re-evaluated in the long-term. The objective of this paper is to determine the long-term (10 years) outcome for patients from a randomised controlled trial (RCT).\nMETHODS: A RCT in 2002 compared laparoscopic adjustable gastric band (LAGB) for obesity with non-surgical therapy. Follow-up has been conducted at 10 years. Eighty patients (BMI 30-35) were randomised to a non-surgical or a surgical program. Outcome data are available on 37 (92.5 %) of the surgical patients and 27 (62.5 %) of the non-surgical patients at 10 years.\nRESULTS: Weight change, the metabolic syndrome, quality of life, adverse events and direct costs of the surgical cohort were the main results of the study. A durable weight loss is present in the surgical group with a mean (SD) 10-year weight loss of 14.1 (7.7) kg (63.4 % EWL), better than the non-surgical group (mean (SD) = 0.4 (10.5) kg; p \u003c 0.001). The metabolic syndrome was reduced from 14 to 4 of the 37 patients who completed 10 years within the LAGB groups. Proximal gastric enlargements occurred in 17 (30 %) of the 57 who had LAGB and removal of the band occurred in 7 (12 %). The annual maintenance costs including additional surgery was AUD $765 per patient per year.\nCONCLUSIONS: Bariatric surgery with the LAGB can achieve long-term weight reduction which is better than a program of non-surgical therapy. There is also a sustained reduction of the metabolic syndrome. There is a significant maintenance requirement after LAGB.","tracks":[{"project":"Allie","denotations":[{"id":"SS1_23760764_3_0","span":{"begin":375,"end":402},"obj":"expanded"},{"id":"SS2_23760764_3_0","span":{"begin":404,"end":407},"obj":"abbr"},{"id":"SS1_23760764_5_0","span":{"begin":442,"end":478},"obj":"expanded"},{"id":"SS2_23760764_5_0","span":{"begin":480,"end":484},"obj":"abbr"}],"relations":[{"id":"AE1_23760764_3_0","pred":"abbreviatedTo","subj":"SS1_23760764_3_0","obj":"SS2_23760764_3_0"},{"id":"AE1_23760764_5_0","pred":"abbreviatedTo","subj":"SS1_23760764_5_0","obj":"SS2_23760764_5_0"}],"attributes":[{"subj":"SS1_23760764_3_0","pred":"source","obj":"Allie"},{"subj":"SS2_23760764_3_0","pred":"source","obj":"Allie"},{"subj":"SS1_23760764_5_0","pred":"source","obj":"Allie"},{"subj":"SS2_23760764_5_0","pred":"source","obj":"Allie"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":221,"end":228},"obj":"HP_0001513"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"Allie","color":"#93ece1","default":true},{"id":"PubmedHPO","color":"#ecc793"}]}]}}