PubMed:23733528 JSONTXT

{"project":"Allie","denotations":[{"id":"SS1_23733528_2_0","span":{"begin":154,"end":182},"obj":"expanded"},{"id":"SS2_23733528_2_0","span":{"begin":184,"end":187},"obj":"abbr"},{"id":"SS1_23733528_8_0","span":{"begin":777,"end":805},"obj":"expanded"},{"id":"SS2_23733528_8_0","span":{"begin":807,"end":810},"obj":"abbr"}],"relations":[{"id":"AE1_23733528_2_0","pred":"abbreviatedTo","subj":"SS1_23733528_2_0","obj":"SS2_23733528_2_0"},{"id":"AE1_23733528_8_0","pred":"abbreviatedTo","subj":"SS1_23733528_8_0","obj":"SS2_23733528_8_0"}],"text":"A medication diary-book for pediatric patients with acute lymphoblastic leukemia in Indonesia.\nBACKGROUND: Event-free survival of pediatric patients with acute lymphoblastic leukemia (ALL) in Yogyakarta, Indonesia was low (20%). The aim of the study was to evaluate the effectiveness of using a medication diary-book on the treatment outcome of childhood ALL.\nPROCEDURE: A randomized study was conducted with 109 pediatric patients with ALL in a pediatric oncology center in Yogyakarta, Indonesia. Both intervention and control groups received a structured parental education program and donated chemotherapy. The intervention group received a medication diary-book to remind parents and families to take oral chemotherapy and present for scheduled appointments or admissions. Event-free survival estimate (EFS) at 3 years was assessed.\nRESULTS: Among pediatric patients with ALL with highly educated mothers (senior high school or higher), the EFS-estimate at 3 years of the intervention group was significantly higher than the EFS-estimate at 3 years of the control group (62% vs. 29%, P = 0.04). Among pediatric patients with ALL with low-educated mothers, no significant difference was found in the EFS-estimates at 3 years between the intervention and control group (26% vs. 18%, P = 0.86).\nCONCLUSIONS: We conclude that a medication diary-book might be useful to improve the survival of pediatric patients with ALL in resource-limited settings, particularly in patients with highly educated mothers."}

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":154,"end":182},"obj":"HP_0006721"},{"id":"T2","span":{"begin":174,"end":182},"obj":"HP_0001909"}],"text":"A medication diary-book for pediatric patients with acute lymphoblastic leukemia in Indonesia.\nBACKGROUND: Event-free survival of pediatric patients with acute lymphoblastic leukemia (ALL) in Yogyakarta, Indonesia was low (20%). The aim of the study was to evaluate the effectiveness of using a medication diary-book on the treatment outcome of childhood ALL.\nPROCEDURE: A randomized study was conducted with 109 pediatric patients with ALL in a pediatric oncology center in Yogyakarta, Indonesia. Both intervention and control groups received a structured parental education program and donated chemotherapy. The intervention group received a medication diary-book to remind parents and families to take oral chemotherapy and present for scheduled appointments or admissions. Event-free survival estimate (EFS) at 3 years was assessed.\nRESULTS: Among pediatric patients with ALL with highly educated mothers (senior high school or higher), the EFS-estimate at 3 years of the intervention group was significantly higher than the EFS-estimate at 3 years of the control group (62% vs. 29%, P = 0.04). Among pediatric patients with ALL with low-educated mothers, no significant difference was found in the EFS-estimates at 3 years between the intervention and control group (26% vs. 18%, P = 0.86).\nCONCLUSIONS: We conclude that a medication diary-book might be useful to improve the survival of pediatric patients with ALL in resource-limited settings, particularly in patients with highly educated mothers."}