PubMed:23730389 JSONTXT

{"project":"Allie","denotations":[{"id":"SS1_23730389_3_0","span":{"begin":248,"end":275},"obj":"expanded"},{"id":"SS2_23730389_3_0","span":{"begin":277,"end":280},"obj":"abbr"},{"id":"SS1_23730389_4_0","span":{"begin":359,"end":392},"obj":"expanded"},{"id":"SS2_23730389_4_0","span":{"begin":394,"end":398},"obj":"abbr"},{"id":"SS1_23730389_7_0","span":{"begin":646,"end":661},"obj":"expanded"},{"id":"SS2_23730389_7_0","span":{"begin":663,"end":665},"obj":"abbr"},{"id":"SS1_23730389_7_1","span":{"begin":668,"end":697},"obj":"expanded"},{"id":"SS2_23730389_7_1","span":{"begin":699,"end":703},"obj":"abbr"},{"id":"SS1_23730389_7_2","span":{"begin":709,"end":742},"obj":"expanded"},{"id":"SS2_23730389_7_2","span":{"begin":744,"end":748},"obj":"abbr"}],"relations":[{"id":"AE1_23730389_3_0","pred":"abbreviatedTo","subj":"SS1_23730389_3_0","obj":"SS2_23730389_3_0"},{"id":"AE1_23730389_4_0","pred":"abbreviatedTo","subj":"SS1_23730389_4_0","obj":"SS2_23730389_4_0"},{"id":"AE1_23730389_7_0","pred":"abbreviatedTo","subj":"SS1_23730389_7_0","obj":"SS2_23730389_7_0"},{"id":"AE1_23730389_7_1","pred":"abbreviatedTo","subj":"SS1_23730389_7_1","obj":"SS2_23730389_7_1"},{"id":"AE1_23730389_7_2","pred":"abbreviatedTo","subj":"SS1_23730389_7_2","obj":"SS2_23730389_7_2"}],"text":"CEUS in the differentiation between low and high-grade bladder carcinoma.\nINTRODUCTION: Bladder cancer ranks 4th overall in the number of newly diagnosed cancers and 10th in causes of cancer deaths. More than 90% of all cases of bladder cancer are transitional cell carcinoma (TCC). The goal of this study is to confirm the usefulness of low mechanical index contrast-enhanced ultrasonography (CEUS), also in association with time-intensity curves, in the differentiation between high- and low-grade bladder malignant lesions.\nMATERIALS AND METHODS: From February 2006 to February 2012 we recruited 144 patients. All patients underwent grayscale ultrasonography (US), color-Doppler ultrasonography (CDUS) and contrast-enhanced ultrasonography (CEUS). Subsequently all patients underwent cystoscopy and TURB.\nRESULTS: HISTOLOGICAL DIAGNOSES WERE: 88 high-grade carcinomas (61.1%), and 56 low-grade carcinomas (38.9%). Sensitivity and specificity of CDUS were 87.5% (126/144) and 60%, respectively. Sensitivity and specificity of CEUS were 90.9% and 85.7%, respectively. Sensitivity and specificity of TIC were 91.6% (132/144) and 85.7%, respectively.\nDISCUSSION AND CONCLUSIONS: CEUS is a reliable noninvasive method for differentiating low- and high-grade bladder carcinomas since it provides typical enhancement patterns as well as specific contrast-sonographic perfusion curves."}

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":88,"end":102},"obj":"HP_0009725"},{"id":"T2","span":{"begin":96,"end":102},"obj":"HP_0002664"},{"id":"T3","span":{"begin":154,"end":161},"obj":"HP_0002664"},{"id":"T4","span":{"begin":184,"end":190},"obj":"HP_0002664"},{"id":"T5","span":{"begin":229,"end":243},"obj":"HP_0009725"},{"id":"T6","span":{"begin":237,"end":243},"obj":"HP_0002664"}],"text":"CEUS in the differentiation between low and high-grade bladder carcinoma.\nINTRODUCTION: Bladder cancer ranks 4th overall in the number of newly diagnosed cancers and 10th in causes of cancer deaths. More than 90% of all cases of bladder cancer are transitional cell carcinoma (TCC). The goal of this study is to confirm the usefulness of low mechanical index contrast-enhanced ultrasonography (CEUS), also in association with time-intensity curves, in the differentiation between high- and low-grade bladder malignant lesions.\nMATERIALS AND METHODS: From February 2006 to February 2012 we recruited 144 patients. All patients underwent grayscale ultrasonography (US), color-Doppler ultrasonography (CDUS) and contrast-enhanced ultrasonography (CEUS). Subsequently all patients underwent cystoscopy and TURB.\nRESULTS: HISTOLOGICAL DIAGNOSES WERE: 88 high-grade carcinomas (61.1%), and 56 low-grade carcinomas (38.9%). Sensitivity and specificity of CDUS were 87.5% (126/144) and 60%, respectively. Sensitivity and specificity of CEUS were 90.9% and 85.7%, respectively. Sensitivity and specificity of TIC were 91.6% (132/144) and 85.7%, respectively.\nDISCUSSION AND CONCLUSIONS: CEUS is a reliable noninvasive method for differentiating low- and high-grade bladder carcinomas since it provides typical enhancement patterns as well as specific contrast-sonographic perfusion curves."}