> top > docs > PubMed:23714854 > annotations

PubMed:23714854 JSONTXT

Annnotations TAB JSON ListView MergeView

PubMed_ArguminSci

Id Subject Object Predicate Lexical cue
T1 108-186 DRI_Background denotes Small cell lung cancer (SCLC) is a subtype of lung cancer with poor prognosis.
T2 187-324 DRI_Outcome denotes Expression array analysis of 23 SCLC cases and 42 normal tissues revealed that EZH2 and other PRC2 members were highly expressed in SCLC.
T3 325-520 DRI_Outcome denotes ChIP-seq for H3K27me3 suggested that genes with H3K27me3(+) in SCLC were extended not only to PRC2-target genes in ES cells but also to other target genes such as cellular adhesion-related genes.
T4 521-677 DRI_Approach denotes These H3K27me3(+) genes in SCLC were repressed significantly, and introduction of the most repressed gene JUB into SCLC cell line lead to growth inhibition.
T5 678-816 DRI_Outcome denotes Shorter overall survival of clinical SCLC cases correlated to repression of JUB alone, or a set of four genes including H3K27me3(+) genes.
T6 817-916 DRI_Background denotes Treatment with EZH2 inhibitors, DZNep and GSK126, resulted in growth repression of SCLC cell lines.
T7 917-1033 DRI_Background denotes High PRC2 expression was suggested to contribute to gene repression in SCLC, and may play a role in genesis of SCLC.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 266-270 gene:2146 denotes EZH2
T1 319-323 disease:C0149925 denotes SCLC
T2 627-630 gene:84962 denotes JUB
T3 636-640 disease:C0149925 denotes SCLC
T4 754-757 gene:84962 denotes JUB
T5 715-719 disease:C0149925 denotes SCLC
T6 832-836 gene:2146 denotes EZH2
T7 900-904 disease:C0149925 denotes SCLC
R1 T0 T1 associated_with EZH2,SCLC
R2 T2 T3 associated_with JUB,SCLC
R3 T4 T5 associated_with JUB,SCLC
R4 T6 T7 associated_with EZH2,SCLC

Allie

Id Subject Object Predicate Lexical cue
SS1_23714854_1_0 108-130 expanded denotes Small cell lung cancer
SS2_23714854_1_0 132-136 abbr denotes SCLC
AE1_23714854_1_0 SS1_23714854_1_0 SS2_23714854_1_0 abbreviatedTo Small cell lung cancer,SCLC

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 108-130 HP_0030357 denotes Small cell lung cancer
T2 119-130 HP_0100526 denotes lung cancer
T3 124-130 HP_0002664 denotes cancer
T4 154-165 HP_0100526 denotes lung cancer
T5 159-165 HP_0002664 denotes cancer

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
23714854-4#106#109#gene84962 627-630 gene84962 denotes JUB
23714854-4#115#119#diseaseC0149925 636-640 diseaseC0149925 denotes SCLC
23714854-6#15#19#gene2146 832-836 gene2146 denotes EZH2
23714854-6#83#87#diseaseC0149925 900-904 diseaseC0149925 denotes SCLC
106#109#gene84962115#119#diseaseC0149925 23714854-4#106#109#gene84962 23714854-4#115#119#diseaseC0149925 associated_with JUB,SCLC
15#19#gene214683#87#diseaseC0149925 23714854-6#15#19#gene2146 23714854-6#83#87#diseaseC0149925 associated_with EZH2,SCLC

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 95-99 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T2 119-123 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T3 154-158 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 84-106 Phenotype denotes small cell lung cancer HP:0030357
T2 108-130 Phenotype denotes Small cell lung cancer HP:0030357
T3 132-136 Phenotype denotes SCLC HP:0030357
T4 154-165 Phenotype denotes lung cancer HP:0100526
T5 219-223 Phenotype denotes SCLC HP:0030357
T6 319-323 Phenotype denotes SCLC HP:0030357
T7 388-392 Phenotype denotes SCLC HP:0030357
T8 548-552 Phenotype denotes SCLC HP:0030357
T9 636-640 Phenotype denotes SCLC HP:0030357
T10 715-719 Phenotype denotes SCLC HP:0030357
T11 900-904 Phenotype denotes SCLC HP:0030357
T12 988-992 Phenotype denotes SCLC HP:0030357
T13 1028-1032 Phenotype denotes SCLC HP:0030357

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 84-106 Disease denotes small cell lung cancer http://purl.obolibrary.org/obo/MONDO_0008433
T2 108-130 Disease denotes Small cell lung cancer http://purl.obolibrary.org/obo/MONDO_0008433
T3 132-136 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433
T4 154-165 Disease denotes lung cancer http://purl.obolibrary.org/obo/MONDO_0008903
T5 219-223 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433
T6 319-323 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433
T7 388-392 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433
T8 548-552 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433
T9 636-640 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433
T10 715-719 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433
T11 900-904 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433
T12 988-992 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433
T13 1028-1032 Disease denotes SCLC http://purl.obolibrary.org/obo/MONDO_0008433

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 95-99 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 119-123 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T3 154-158 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048