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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-137 Sentence denotes Beyond orchids and dandelions: testing the 5-HTT "risky" allele for evidence of phenotypic capacitance and frequency-dependent selection.
TextSentencer_T2 138-266 Sentence denotes The persistence of behaviorally deleterious genes in the human population poses an interesting question for population genetics:
TextSentencer_T3 267-358 Sentence denotes If certain alleles at these loci are deleterious, why have they survived in the population?
TextSentencer_T4 359-643 Sentence denotes We consider evidence for phenotypic capacitance and/or frequency-dependent selection for an allele that has been putatively shown to have negative associations with human behaviors (the "short" 5-HTT promoter region allele) yet has persisted in human and nonhuman primate populations.
TextSentencer_T5 644-878 Sentence denotes Using data from the National Longitudinal Study of Adolescent Health, we compare sibling and twin variation in depression by 5-HTT genotype (specified in several ways) and investigate sibship-level cross-person gene-gene interactions.
TextSentencer_T6 879-1112 Sentence denotes In support of the "orchid/dandelion" hypothesis, we find evidence that the short allele increases variation in phenotypes in response to environmental (or genetic) differences (i.e., acts as a perturbation of a phenotypic capacitor).
TextSentencer_T7 1113-1330 Sentence denotes Further, we also find some evidence that the effects of allelic variation at this locus are moderated by the genetic environment of the sibship unit (i.e., effects may be susceptible to frequency-dependent selection).
TextSentencer_T8 1331-1528 Sentence denotes We discuss implications of these findings for genetic models in general, specifically with respect to stable unit treatment value assumption violations (i.e., nonindependence of units of analysis).
T1 0-137 Sentence denotes Beyond orchids and dandelions: testing the 5-HTT "risky" allele for evidence of phenotypic capacitance and frequency-dependent selection.
T2 138-266 Sentence denotes The persistence of behaviorally deleterious genes in the human population poses an interesting question for population genetics:
T3 267-358 Sentence denotes If certain alleles at these loci are deleterious, why have they survived in the population?
T4 359-643 Sentence denotes We consider evidence for phenotypic capacitance and/or frequency-dependent selection for an allele that has been putatively shown to have negative associations with human behaviors (the "short" 5-HTT promoter region allele) yet has persisted in human and nonhuman primate populations.
T5 644-878 Sentence denotes Using data from the National Longitudinal Study of Adolescent Health, we compare sibling and twin variation in depression by 5-HTT genotype (specified in several ways) and investigate sibship-level cross-person gene-gene interactions.
T6 879-1112 Sentence denotes In support of the "orchid/dandelion" hypothesis, we find evidence that the short allele increases variation in phenotypes in response to environmental (or genetic) differences (i.e., acts as a perturbation of a phenotypic capacitor).
T7 1113-1330 Sentence denotes Further, we also find some evidence that the effects of allelic variation at this locus are moderated by the genetic environment of the sibship unit (i.e., effects may be susceptible to frequency-dependent selection).
T8 1331-1528 Sentence denotes We discuss implications of these findings for genetic models in general, specifically with respect to stable unit treatment value assumption violations (i.e., nonindependence of units of analysis).

DisGeNET

Id Subject Object Predicate Lexical cue
T0 769-774 gene:6532 denotes 5-HTT
T1 755-765 disease:C0011570 denotes depression
T2 769-774 gene:6532 denotes 5-HTT
T3 755-765 disease:C0011581 denotes depression
T4 769-774 gene:6532 denotes 5-HTT
T5 755-765 disease:C0812393 denotes depression
R1 T0 T1 associated_with 5-HTT,depression
R2 T2 T3 associated_with 5-HTT,depression
R3 T4 T5 associated_with 5-HTT,depression

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 755-765 HP_0000716 denotes depression

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
23701535-3#125#130#gene6532 769-774 gene6532 denotes 5-HTT
23701535-3#111#121#diseaseC0011570 755-765 diseaseC0011570 denotes depression
23701535-3#111#121#diseaseC0011581 755-765 diseaseC0011581 denotes depression
125#130#gene6532111#121#diseaseC0011570 23701535-3#125#130#gene6532 23701535-3#111#121#diseaseC0011570 associated_with 5-HTT,depression
125#130#gene6532111#121#diseaseC0011581 23701535-3#125#130#gene6532 23701535-3#111#121#diseaseC0011581 associated_with 5-HTT,depression

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2316 769-774 gene:6532 denotes 5-HTT
T2317 755-765 disease:C0011570 denotes depression
R1 T2316 T2317 associated_with 5-HTT,depression
R2 T2316 T2317 associated_with 5-HTT,depression