PubMed:23667712
Annnotations
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-96 | Sentence | denotes | Effects of resveratrol in pregnancy using murine models with reduced blood supply to the uterus. |
| TextSentencer_T2 | 97-221 | Sentence | denotes | Preeclampsia (PE) and fetal growth restriction (FGR) contribute significantly to fetal and maternal morbidity and mortality. |
| TextSentencer_T3 | 222-365 | Sentence | denotes | Although the causes of PE and FGR are not fully understood, both conditions are known to be associated with impaired uterine artery blood flow. |
| TextSentencer_T4 | 366-561 | Sentence | denotes | Resveratrol, a polyphenol found in a number of plants, has been shown to induce relaxation of uterine arteries in vitro as well as improve many pathological conditions associated with PE and FGR. |
| TextSentencer_T5 | 562-863 | Sentence | denotes | We hypothesized that treatment of endothelial nitric oxide synthase knockout mice (eNOS⁻/⁻) and catechol-O-methyltransferase knockout mice (COMT⁻/⁻) with resveratrol during pregnancy would improve uterine artery blood flow and therefore ameliorate the PE-like phenotype and FGR in these murine models. |
| TextSentencer_T6 | 864-1029 | Sentence | denotes | Pregnant C57BL/6J, eNOS⁻/⁻ and COMT⁻/⁻ mice received either resveratrol supplemented diet (4 g/kg diet) or control diet between gestational day (GD) 0.5 and GD 18.5. |
| TextSentencer_T7 | 1030-1169 | Sentence | denotes | Resveratrol supplementation significantly increased uterine artery blood flow velocity and fetal weight in COMT⁻/⁻ but not in eNOS⁻/⁻ mice. |
| TextSentencer_T8 | 1170-1260 | Sentence | denotes | There were no effects of resveratrol on litter size and placental weight among the groups. |
| TextSentencer_T9 | 1261-1429 | Sentence | denotes | In conclusion, resveratrol increased uterine artery blood flow velocity and fetal weight in COMT⁻/⁻ mice, suggesting potential as a therapeutic strategy for PE and FGR. |
| T1 | 0-96 | Sentence | denotes | Effects of resveratrol in pregnancy using murine models with reduced blood supply to the uterus. |
| T2 | 97-221 | Sentence | denotes | Preeclampsia (PE) and fetal growth restriction (FGR) contribute significantly to fetal and maternal morbidity and mortality. |
| T3 | 222-365 | Sentence | denotes | Although the causes of PE and FGR are not fully understood, both conditions are known to be associated with impaired uterine artery blood flow. |
| T4 | 366-561 | Sentence | denotes | Resveratrol, a polyphenol found in a number of plants, has been shown to induce relaxation of uterine arteries in vitro as well as improve many pathological conditions associated with PE and FGR. |
| T5 | 562-863 | Sentence | denotes | We hypothesized that treatment of endothelial nitric oxide synthase knockout mice (eNOS⁻/⁻) and catechol-O-methyltransferase knockout mice (COMT⁻/⁻) with resveratrol during pregnancy would improve uterine artery blood flow and therefore ameliorate the PE-like phenotype and FGR in these murine models. |
| T6 | 864-1029 | Sentence | denotes | Pregnant C57BL/6J, eNOS⁻/⁻ and COMT⁻/⁻ mice received either resveratrol supplemented diet (4 g/kg diet) or control diet between gestational day (GD) 0.5 and GD 18.5. |
| T7 | 1030-1169 | Sentence | denotes | Resveratrol supplementation significantly increased uterine artery blood flow velocity and fetal weight in COMT⁻/⁻ but not in eNOS⁻/⁻ mice. |
| T8 | 1170-1260 | Sentence | denotes | There were no effects of resveratrol on litter size and placental weight among the groups. |
| T9 | 1261-1429 | Sentence | denotes | In conclusion, resveratrol increased uterine artery blood flow velocity and fetal weight in COMT⁻/⁻ mice, suggesting potential as a therapeutic strategy for PE and FGR. |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 97-109 | HP_0100602 | denotes | Preeclampsia |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_23667712_1_0 | 97-109 | expanded | denotes | Preeclampsia |
| SS2_23667712_1_0 | 111-113 | abbr | denotes | PE |
| SS1_23667712_1_1 | 119-143 | expanded | denotes | fetal growth restriction |
| SS2_23667712_1_1 | 145-148 | abbr | denotes | FGR |
| SS1_23667712_5_0 | 992-1007 | expanded | denotes | gestational day |
| SS2_23667712_5_0 | 1009-1011 | abbr | denotes | GD |
| AE1_23667712_1_0 | SS1_23667712_1_0 | SS2_23667712_1_0 | abbreviatedTo | Preeclampsia,PE |
| AE1_23667712_1_1 | SS1_23667712_1_1 | SS2_23667712_1_1 | abbreviatedTo | fetal growth restriction,FGR |
| AE1_23667712_5_0 | SS1_23667712_5_0 | SS2_23667712_5_0 | abbreviatedTo | gestational day,GD |
Preeclampsia
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-Preeclampsia-B_T1 | 97-109 | ORPHA:275555 | denotes | Preeclampsia |
Preeclampsia-compare
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-Preeclampsia-B_T1 | 97-109 | ORPHA:275555 | denotes | Preeclampsia |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 69-74 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T2 | 354-359 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T3 | 774-779 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T4 | 1097-1102 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T5 | 1313-1318 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T6 | 89-95 | http://purl.obolibrary.org/obo/UBERON_0000995 | denotes | uterus |
| PD-UBERON-AE-B_T7 | 339-353 | http://purl.obolibrary.org/obo/UBERON_0002493 | denotes | uterine artery |
| PD-UBERON-AE-B_T8 | 759-773 | http://purl.obolibrary.org/obo/UBERON_0002493 | denotes | uterine artery |
| PD-UBERON-AE-B_T9 | 1082-1096 | http://purl.obolibrary.org/obo/UBERON_0002493 | denotes | uterine artery |
| PD-UBERON-AE-B_T10 | 1298-1312 | http://purl.obolibrary.org/obo/UBERON_0002493 | denotes | uterine artery |
| PD-UBERON-AE-B_T11 | 347-353 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| PD-UBERON-AE-B_T12 | 767-773 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| PD-UBERON-AE-B_T13 | 1090-1096 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| PD-UBERON-AE-B_T14 | 1306-1312 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| PD-UBERON-AE-B_T15 | 347-359 | http://purl.obolibrary.org/obo/UBERON_0013755 | denotes | artery blood |
| PD-UBERON-AE-B_T16 | 767-779 | http://purl.obolibrary.org/obo/UBERON_0013755 | denotes | artery blood |
| PD-UBERON-AE-B_T17 | 1090-1102 | http://purl.obolibrary.org/obo/UBERON_0013755 | denotes | artery blood |
| PD-UBERON-AE-B_T18 | 1306-1318 | http://purl.obolibrary.org/obo/UBERON_0013755 | denotes | artery blood |
preeclampsia_genes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-PreeclampsiaGenes-B_T1 | 658-686 | HGNC:COMT | denotes | catechol-O-methyltransferase |
| PD-PreeclampsiaGenes-B_T2 | 608-629 | HGNC:NOS3 | denotes | nitric oxide synthase |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 69-74 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T2 | 354-359 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T3 | 774-779 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T4 | 1097-1102 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T5 | 1313-1318 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T6 | 347-353 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| PD-UBERON-AE-B_T7 | 468-476 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | arteries |
| PD-UBERON-AE-B_T8 | 767-773 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| PD-UBERON-AE-B_T9 | 1090-1096 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| PD-UBERON-AE-B_T10 | 1306-1312 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| PD-UBERON-AE-B_T11 | 1226-1235 | http://purl.obolibrary.org/obo/UBERON_0001987 | denotes | placental |
| PD-UBERON-AE-B_T12 | 89-95 | http://purl.obolibrary.org/obo/UBERON_0000995 | denotes | uterus |
| PD-UBERON-AE-B_T13 | 339-353 | http://purl.obolibrary.org/obo/UBERON_0002493 | denotes | uterine artery |
| PD-UBERON-AE-B_T14 | 460-476 | http://purl.obolibrary.org/obo/UBERON_0002493 | denotes | uterine arteries |
| PD-UBERON-AE-B_T15 | 759-773 | http://purl.obolibrary.org/obo/UBERON_0002493 | denotes | uterine artery |
| PD-UBERON-AE-B_T16 | 1082-1096 | http://purl.obolibrary.org/obo/UBERON_0002493 | denotes | uterine artery |
| PD-UBERON-AE-B_T17 | 1298-1312 | http://purl.obolibrary.org/obo/UBERON_0002493 | denotes | uterine artery |
| PD-UBERON-AE-B_T18 | 347-359 | http://purl.obolibrary.org/obo/UBERON_0013755 | denotes | artery blood |
| PD-UBERON-AE-B_T19 | 767-779 | http://purl.obolibrary.org/obo/UBERON_0013755 | denotes | artery blood |
| PD-UBERON-AE-B_T20 | 1090-1102 | http://purl.obolibrary.org/obo/UBERON_0013755 | denotes | artery blood |
| PD-UBERON-AE-B_T21 | 1306-1318 | http://purl.obolibrary.org/obo/UBERON_0013755 | denotes | artery blood |