PubMed:23612222 JSONTXT

{"project":"Allie","denotations":[{"id":"SS1_23612222_2_0","span":{"begin":139,"end":169},"obj":"expanded"},{"id":"SS2_23612222_2_0","span":{"begin":171,"end":175},"obj":"abbr"}],"relations":[{"id":"AE1_23612222_2_0","pred":"abbreviatedTo","subj":"SS1_23612222_2_0","obj":"SS2_23612222_2_0"}],"text":"Pragmatic exercise intervention in people with mild to moderate multiple sclerosis: a randomised controlled feasibility study.\nBACKGROUND: People with Multiple Sclerosis (PwMS) are less physically active than the general population and pragmatic approaches designed to equip them with the skills and confidence to participate in long-term physical activity are required.\nOBJECTIVE: The objective of this study was to determine the feasibility of a pragmatic exercise intervention in PwMS.\nMETHODS: A voluntary sample of 30 PwMS (male n = 4, female n = 26; mean age = 40 years; range = 24-49 years), with mild to moderate disability (EDSS ≤ 5.5), were recruited from eligible participants attending outpatient clinics. A total of 28 participants were randomised to a 10 week pragmatic exercise intervention (2× supervised and 1× home-based session per week) or usual care. Clinical, functional and quality of life (MSQoL-54) outcomes were assessed at baseline, immediately and 3 months after the intervention.\nRESULTS: Attrition was low (2 participants lost to immediate follow-up and 4 participants lost to 3 month follow-up), with high compliance rates (\u003e75% of all sessions). The intervention group achieved progression of exercise volume (24.3 ± 7.0 to 30.9 ± 5.5 min per session), intensity (60.4 ± 8.8 to 67.7 ± 6.9% HR max) and training impulse (min × average HR=training impulse/load [arbitrary units; AU]) (2600 ± 1105 to 3210 ± 1269AU) during the intervention, whilst significantly increasing(P = 0.050) their physical composite score (MSQOL-54) at 10 weeks and readiness to exercise (P = 0.003) at 3 months compared with usual care.\nCONCLUSION: This pragmatic intervention was feasible for PwMS, but further research is needed to assess its long-term impact on physical activity behaviour."}

{"project":"chenxin_473849_800","denotations":[{"id":"T1","span":{"begin":64,"end":82},"obj":"DP"},{"id":"T2","span":{"begin":151,"end":169},"obj":"DP"},{"id":"T3","span":{"begin":171,"end":175},"obj":"DP"},{"id":"T4","span":{"begin":483,"end":487},"obj":"DP"},{"id":"T5","span":{"begin":523,"end":527},"obj":"DP"},{"id":"T6","span":{"begin":1700,"end":1704},"obj":"DP"}],"text":"Pragmatic exercise intervention in people with mild to moderate multiple sclerosis: a randomised controlled feasibility study.\nBACKGROUND: People with Multiple Sclerosis (PwMS) are less physically active than the general population and pragmatic approaches designed to equip them with the skills and confidence to participate in long-term physical activity are required.\nOBJECTIVE: The objective of this study was to determine the feasibility of a pragmatic exercise intervention in PwMS.\nMETHODS: A voluntary sample of 30 PwMS (male n = 4, female n = 26; mean age = 40 years; range = 24-49 years), with mild to moderate disability (EDSS ≤ 5.5), were recruited from eligible participants attending outpatient clinics. A total of 28 participants were randomised to a 10 week pragmatic exercise intervention (2× supervised and 1× home-based session per week) or usual care. Clinical, functional and quality of life (MSQoL-54) outcomes were assessed at baseline, immediately and 3 months after the intervention.\nRESULTS: Attrition was low (2 participants lost to immediate follow-up and 4 participants lost to 3 month follow-up), with high compliance rates (\u003e75% of all sessions). The intervention group achieved progression of exercise volume (24.3 ± 7.0 to 30.9 ± 5.5 min per session), intensity (60.4 ± 8.8 to 67.7 ± 6.9% HR max) and training impulse (min × average HR=training impulse/load [arbitrary units; AU]) (2600 ± 1105 to 3210 ± 1269AU) during the intervention, whilst significantly increasing(P = 0.050) their physical composite score (MSQOL-54) at 10 weeks and readiness to exercise (P = 0.003) at 3 months compared with usual care.\nCONCLUSION: This pragmatic intervention was feasible for PwMS, but further research is needed to assess its long-term impact on physical activity behaviour."}

{"project":"Zierdiyeerkenaili_800_3","denotations":[{"id":"T1","span":{"begin":171,"end":175},"obj":"DP"},{"id":"T2","span":{"begin":483,"end":487},"obj":"DP"},{"id":"T3","span":{"begin":523,"end":527},"obj":"DP"},{"id":"T4","span":{"begin":1700,"end":1704},"obj":"DP"},{"id":"T5","span":{"begin":139,"end":169},"obj":"DP"},{"id":"T6","span":{"begin":35,"end":82},"obj":"DP"}],"text":"Pragmatic exercise intervention in people with mild to moderate multiple sclerosis: a randomised controlled feasibility study.\nBACKGROUND: People with Multiple Sclerosis (PwMS) are less physically active than the general population and pragmatic approaches designed to equip them with the skills and confidence to participate in long-term physical activity are required.\nOBJECTIVE: The objective of this study was to determine the feasibility of a pragmatic exercise intervention in PwMS.\nMETHODS: A voluntary sample of 30 PwMS (male n = 4, female n = 26; mean age = 40 years; range = 24-49 years), with mild to moderate disability (EDSS ≤ 5.5), were recruited from eligible participants attending outpatient clinics. A total of 28 participants were randomised to a 10 week pragmatic exercise intervention (2× supervised and 1× home-based session per week) or usual care. Clinical, functional and quality of life (MSQoL-54) outcomes were assessed at baseline, immediately and 3 months after the intervention.\nRESULTS: Attrition was low (2 participants lost to immediate follow-up and 4 participants lost to 3 month follow-up), with high compliance rates (\u003e75% of all sessions). The intervention group achieved progression of exercise volume (24.3 ± 7.0 to 30.9 ± 5.5 min per session), intensity (60.4 ± 8.8 to 67.7 ± 6.9% HR max) and training impulse (min × average HR=training impulse/load [arbitrary units; AU]) (2600 ± 1105 to 3210 ± 1269AU) during the intervention, whilst significantly increasing(P = 0.050) their physical composite score (MSQOL-54) at 10 weeks and readiness to exercise (P = 0.003) at 3 months compared with usual care.\nCONCLUSION: This pragmatic intervention was feasible for PwMS, but further research is needed to assess its long-term impact on physical activity behaviour."}

{"project":"yaoziqian_800_3","denotations":[{"id":"T3","span":{"begin":171,"end":175},"obj":"DP"},{"id":"T4","span":{"begin":483,"end":487},"obj":"DP"},{"id":"T5","span":{"begin":523,"end":527},"obj":"DP"},{"id":"T6","span":{"begin":1700,"end":1704},"obj":"DP"},{"id":"T7","span":{"begin":35,"end":82},"obj":"DP"},{"id":"T8","span":{"begin":139,"end":169},"obj":"DP"}],"text":"Pragmatic exercise intervention in people with mild to moderate multiple sclerosis: a randomised controlled feasibility study.\nBACKGROUND: People with Multiple Sclerosis (PwMS) are less physically active than the general population and pragmatic approaches designed to equip them with the skills and confidence to participate in long-term physical activity are required.\nOBJECTIVE: The objective of this study was to determine the feasibility of a pragmatic exercise intervention in PwMS.\nMETHODS: A voluntary sample of 30 PwMS (male n = 4, female n = 26; mean age = 40 years; range = 24-49 years), with mild to moderate disability (EDSS ≤ 5.5), were recruited from eligible participants attending outpatient clinics. A total of 28 participants were randomised to a 10 week pragmatic exercise intervention (2× supervised and 1× home-based session per week) or usual care. Clinical, functional and quality of life (MSQoL-54) outcomes were assessed at baseline, immediately and 3 months after the intervention.\nRESULTS: Attrition was low (2 participants lost to immediate follow-up and 4 participants lost to 3 month follow-up), with high compliance rates (\u003e75% of all sessions). The intervention group achieved progression of exercise volume (24.3 ± 7.0 to 30.9 ± 5.5 min per session), intensity (60.4 ± 8.8 to 67.7 ± 6.9% HR max) and training impulse (min × average HR=training impulse/load [arbitrary units; AU]) (2600 ± 1105 to 3210 ± 1269AU) during the intervention, whilst significantly increasing(P = 0.050) their physical composite score (MSQOL-54) at 10 weeks and readiness to exercise (P = 0.003) at 3 months compared with usual care.\nCONCLUSION: This pragmatic intervention was feasible for PwMS, but further research is needed to assess its long-term impact on physical activity behaviour."}