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PubMed:23611123 JSONTXT

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Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 26-31 http://purl.obolibrary.org/obo/MAT_0000058 denotes urine
T2 519-524 http://purl.obolibrary.org/obo/MAT_0000058 denotes urine
T3 1154-1176 http://purl.obolibrary.org/obo/MAT_0000457 denotes central nervous system
T4 1162-1176 http://purl.obolibrary.org/obo/MAT_0000026 denotes nervous system
T5 1407-1412 http://purl.obolibrary.org/obo/MAT_0000058 denotes urine

Allie

Id Subject Object Predicate Lexical cue
SS1_23611123_2_0 597-634 expanded denotes variable importance to the projection
SS2_23611123_2_0 636-639 abbr denotes VIP
SS1_23611123_2_1 801-844 expanded denotes partial least-squares discriminant analysis
SS2_23611123_2_1 846-852 abbr denotes PLS-DA
SS1_23611123_2_2 871-899 expanded denotes Monte Carlo cross validation
SS2_23611123_2_2 901-905 abbr denotes MCCV
AE1_23611123_2_0 SS1_23611123_2_0 SS2_23611123_2_0 abbreviatedTo variable importance to the projection,VIP
AE1_23611123_2_1 SS1_23611123_2_1 SS2_23611123_2_1 abbreviatedTo partial least-squares discriminant analysis,PLS-DA
AE1_23611123_2_2 SS1_23611123_2_2 SS2_23611123_2_2 abbreviatedTo Monte Carlo cross validation,MCCV

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 189-205 HP_0001622 denotes preterm delivery
T2 207-238 HP_0001511 denotes intrauterine growth restriction
T3 240-252 HP_0100602 denotes preeclampsia
T4 257-277 HP_0009800 denotes gestational diabetes
T5 269-286 HP_0000819 denotes diabetes mellitus
T6 1066-1096 HP_0001788 denotes premature rupture of membranes
T7 1154-1190 HP_0002011 denotes central nervous system malformations
T8 1162-1190 HP_0000707 denotes nervous system malformations
T9 1204-1220 HP_0001622 denotes preterm delivery
T10 1222-1242 HP_0009800 denotes gestational diabetes
T11 1244-1275 HP_0001511 denotes intrauterine growth restriction
T12 1280-1292 HP_0100602 denotes preeclampsia

Preeclampsia

Id Subject Object Predicate Lexical cue
PD-Preeclampsia-B_T1 240-252 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T2 1280-1292 ORPHA:275555 denotes preeclampsia

Preeclampsia-compare

Id Subject Object Predicate Lexical cue
PD-Preeclampsia-B_T1 240-252 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T2 1280-1292 ORPHA:275555 denotes preeclampsia

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-106 Sentence denotes Second trimester maternal urine for the diagnosis of trisomy 21 and prediction of poor pregnancy outcomes.
TextSentencer_T2 107-588 Sentence denotes Given the recognized lack of prenatal clinical methods for the early diagnosis of preterm delivery, intrauterine growth restriction, preeclampsia and gestational diabetes mellitus, and the continuing need for optimized diagnosis methods for specific chromosomal disorders (e.g., trisomy 21) and fetal malformations, this work sought specific metabolic signatures of these conditions in second trimester maternal urine, using (1)H Nuclear Magnetic Resonance ((1)H NMR) metabolomics.
TextSentencer_T3 589-964 Sentence denotes Several variable importance to the projection (VIP)- and b-coefficient-based variable selection methods were tested, both individually and through their intersection, and the resulting data sets were analyzed by partial least-squares discriminant analysis (PLS-DA) and submitted to Monte Carlo cross validation (MCCV) and permutation tests to evaluate model predictive power.
TextSentencer_T4 965-1097 Sentence denotes The NMR data subsets produced significantly improved PLS-DA models for all conditions except for pre-premature rupture of membranes.
TextSentencer_T5 1098-1340 Sentence denotes Specific urinary metabolic signatures were unveiled for central nervous system malformations, trisomy 21, preterm delivery, gestational diabetes, intrauterine growth restriction and preeclampsia, and biochemical interpretations were proposed.
TextSentencer_T6 1341-1528 Sentence denotes This work demonstrated, for the first time, the value of maternal urine profiling as a complementary means of prenatal diagnostics and early prediction of several poor pregnancy outcomes.
T1 0-106 Sentence denotes Second trimester maternal urine for the diagnosis of trisomy 21 and prediction of poor pregnancy outcomes.
T2 107-588 Sentence denotes Given the recognized lack of prenatal clinical methods for the early diagnosis of preterm delivery, intrauterine growth restriction, preeclampsia and gestational diabetes mellitus, and the continuing need for optimized diagnosis methods for specific chromosomal disorders (e.g., trisomy 21) and fetal malformations, this work sought specific metabolic signatures of these conditions in second trimester maternal urine, using (1)H Nuclear Magnetic Resonance ((1)H NMR) metabolomics.
T3 589-964 Sentence denotes Several variable importance to the projection (VIP)- and b-coefficient-based variable selection methods were tested, both individually and through their intersection, and the resulting data sets were analyzed by partial least-squares discriminant analysis (PLS-DA) and submitted to Monte Carlo cross validation (MCCV) and permutation tests to evaluate model predictive power.
T4 965-1097 Sentence denotes The NMR data subsets produced significantly improved PLS-DA models for all conditions except for pre-premature rupture of membranes.
T5 1098-1340 Sentence denotes Specific urinary metabolic signatures were unveiled for central nervous system malformations, trisomy 21, preterm delivery, gestational diabetes, intrauterine growth restriction and preeclampsia, and biochemical interpretations were proposed.
T6 1341-1528 Sentence denotes This work demonstrated, for the first time, the value of maternal urine profiling as a complementary means of prenatal diagnostics and early prediction of several poor pregnancy outcomes.

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 26-31 http://purl.obolibrary.org/obo/UBERON_0001088 denotes urine
PD-UBERON-AE-B_T2 519-524 http://purl.obolibrary.org/obo/UBERON_0001088 denotes urine
PD-UBERON-AE-B_T3 1407-1412 http://purl.obolibrary.org/obo/UBERON_0001088 denotes urine
PD-UBERON-AE-B_T4 1154-1161 http://purl.obolibrary.org/obo/UBERON_0012131 denotes central
PD-UBERON-AE-B_T5 1154-1176 http://purl.obolibrary.org/obo/UBERON_0001017 denotes central nervous system
PD-UBERON-AE-B_T6 1162-1176 http://purl.obolibrary.org/obo/UBERON_0001016 denotes nervous system

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1154-1161 http://purl.obolibrary.org/obo/UBERON_0012131 denotes central
PD-UBERON-AE-B_T2 1154-1176 http://purl.obolibrary.org/obo/UBERON_0001017 denotes central nervous system
PD-UBERON-AE-B_T3 1162-1176 http://purl.obolibrary.org/obo/UBERON_0001016 denotes nervous system
PD-UBERON-AE-B_T4 26-31 http://purl.obolibrary.org/obo/UBERON_0001088 denotes urine
PD-UBERON-AE-B_T5 519-524 http://purl.obolibrary.org/obo/UBERON_0001088 denotes urine
PD-UBERON-AE-B_T6 1407-1412 http://purl.obolibrary.org/obo/UBERON_0001088 denotes urine

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 53-63 Disease denotes trisomy 21 http://purl.obolibrary.org/obo/MONDO_0008608
T2 207-238 Disease denotes intrauterine growth restriction http://purl.obolibrary.org/obo/MONDO_0005030
T3 240-252 Disease denotes preeclampsia http://purl.obolibrary.org/obo/MONDO_0005081
T4 257-286 Disease denotes gestational diabetes mellitus http://purl.obolibrary.org/obo/MONDO_0005406
T5 357-378 Disease denotes chromosomal disorders http://purl.obolibrary.org/obo/MONDO_0019040
T6 386-396 Disease denotes trisomy 21 http://purl.obolibrary.org/obo/MONDO_0008608
T7 402-421 Disease denotes fetal malformations http://purl.obolibrary.org/obo/MONDO_0000839
T8 1154-1190 Disease denotes central nervous system malformations http://purl.obolibrary.org/obo/MONDO_0020022
T9 1192-1202 Disease denotes trisomy 21 http://purl.obolibrary.org/obo/MONDO_0008608
T10 1222-1242 Disease denotes gestational diabetes http://purl.obolibrary.org/obo/MONDO_0005406
T11 1244-1275 Disease denotes intrauterine growth restriction http://purl.obolibrary.org/obo/MONDO_0005030
T12 1280-1292 Disease denotes preeclampsia http://purl.obolibrary.org/obo/MONDO_0005081

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 26-31 Body_part denotes urine http://purl.obolibrary.org/obo/MAT_0000058
T2 519-524 Body_part denotes urine http://purl.obolibrary.org/obo/MAT_0000058
T3 1154-1176 Body_part denotes central nervous system http://purl.obolibrary.org/obo/MAT_0000457
T4 1407-1412 Body_part denotes urine http://purl.obolibrary.org/obo/MAT_0000058

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 26-31 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T2 519-524 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T3 1087-1096 Body_part denotes membranes http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T6 1154-1176 Body_part denotes central nervous system http://purl.obolibrary.org/obo/UBERON_0001017
T7 1407-1412 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 189-205 Phenotype denotes preterm delivery HP:0001622
T2 207-238 Phenotype denotes intrauterine growth restriction HP:0001511
T3 269-286 Phenotype denotes diabetes mellitus HP:0000819
T4 1066-1096 Phenotype denotes premature rupture of membranes HP:0001788
T5 1204-1220 Phenotype denotes preterm delivery HP:0001622
T6 1244-1275 Phenotype denotes intrauterine growth restriction HP:0001511