| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-89 |
Sentence |
denotes |
Levels of cytokines in umbilical cord blood in small for gestational age preterm infants. |
| T2 |
90-103 |
Sentence |
denotes |
INTRODUCTION: |
| T3 |
104-274 |
Sentence |
denotes |
Being born small for gestational age (SGA) can be a reference to intrauterine growth retardation (IUGR) and is associated with increased neonatal morbidity and mortality. |
| T4 |
275-405 |
Sentence |
denotes |
In pregnancies complicated by IUGR placental insufficiency is thought to be one of the leading underlying pathogenetic mechanisms. |
| T5 |
406-567 |
Sentence |
denotes |
As cytokines appear to be implicated in implantation and -placental development, imbalances in cytokine levels may contribute to pregnancy disorders i. e., IUGR. |
| T6 |
568-578 |
Sentence |
denotes |
OBJECTIVE: |
| T7 |
579-750 |
Sentence |
denotes |
Cord blood cytokine profiles were analyzed in order to characterize differences in cytokine profiles between SGA and appropriate for gestational age (AGA) preterm infants. |
| T8 |
751-759 |
Sentence |
denotes |
METHODS: |
| T9 |
760-951 |
Sentence |
denotes |
Cytokine concentrations were measured in venous cord blood of preterm infants delivered by caesarean section without previous labour activity and without signs of maternal or fetal infection. |
| T10 |
952-960 |
Sentence |
denotes |
RESULTS: |
| T11 |
961-1153 |
Sentence |
denotes |
93 preterm infants were enrolled, 29 SGA preterm infants (GA 31.0 (24.6-36.7) weeks; BW 1080 (315-2010) grams) and 63 AGA preterm infants (GA 33.3 (26.0-36.9) weeks; BW 1790 (760-3570) grams). |
| T12 |
1154-1206 |
Sentence |
denotes |
In both groups multiple cytokines could be detected. |
| T13 |
1207-1403 |
Sentence |
denotes |
Significant differences in cytokine levels between the groups were found for G-CSF, IL-12p40 and IL-8, while levels of IL-1a, IL-6, IL-10, IP-10, MCP-1, MCP-3, MIP-1a and TNF-a were not different. |
| T14 |
1404-1416 |
Sentence |
denotes |
CONCLUSIONS: |
| T15 |
1417-1589 |
Sentence |
denotes |
Alteration of cytokine levels in SGA preterm infants may be involved in the pathogenesis of reduced intrauterine growth as well as in the higher morbidity in these infants. |
| T16 |
1590-1715 |
Sentence |
denotes |
Further studies are needed to get more comprehension of the complex function of cytokines in pregnancies complicated by IUGR. |
| T1 |
0-89 |
Sentence |
denotes |
Levels of cytokines in umbilical cord blood in small for gestational age preterm infants. |
| T2 |
90-103 |
Sentence |
denotes |
INTRODUCTION: |
| T3 |
104-274 |
Sentence |
denotes |
Being born small for gestational age (SGA) can be a reference to intrauterine growth retardation (IUGR) and is associated with increased neonatal morbidity and mortality. |
| T4 |
275-405 |
Sentence |
denotes |
In pregnancies complicated by IUGR placental insufficiency is thought to be one of the leading underlying pathogenetic mechanisms. |
| T5 |
406-567 |
Sentence |
denotes |
As cytokines appear to be implicated in implantation and -placental development, imbalances in cytokine levels may contribute to pregnancy disorders i. e., IUGR. |
| T6 |
568-578 |
Sentence |
denotes |
OBJECTIVE: |
| T7 |
579-750 |
Sentence |
denotes |
Cord blood cytokine profiles were analyzed in order to characterize differences in cytokine profiles between SGA and appropriate for gestational age (AGA) preterm infants. |
| T8 |
751-759 |
Sentence |
denotes |
METHODS: |
| T9 |
760-951 |
Sentence |
denotes |
Cytokine concentrations were measured in venous cord blood of preterm infants delivered by caesarean section without previous labour activity and without signs of maternal or fetal infection. |
| T10 |
952-960 |
Sentence |
denotes |
RESULTS: |
| T11 |
961-1153 |
Sentence |
denotes |
93 preterm infants were enrolled, 29 SGA preterm infants (GA 31.0 (24.6-36.7) weeks; BW 1080 (315-2010) grams) and 63 AGA preterm infants (GA 33.3 (26.0-36.9) weeks; BW 1790 (760-3570) grams). |
| T12 |
1154-1206 |
Sentence |
denotes |
In both groups multiple cytokines could be detected. |
| T13 |
1207-1403 |
Sentence |
denotes |
Significant differences in cytokine levels between the groups were found for G-CSF, IL-12p40 and IL-8, while levels of IL-1a, IL-6, IL-10, IP-10, MCP-1, MCP-3, MIP-1a and TNF-a were not different. |
| T14 |
1404-1416 |
Sentence |
denotes |
CONCLUSIONS: |
| T15 |
1417-1589 |
Sentence |
denotes |
Alteration of cytokine levels in SGA preterm infants may be involved in the pathogenesis of reduced intrauterine growth as well as in the higher morbidity in these infants. |
| T16 |
1590-1715 |
Sentence |
denotes |
Further studies are needed to get more comprehension of the complex function of cytokines in pregnancies complicated by IUGR. |