PubMed:23514715
Annnotations
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 112-123 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T2 | 1371-1382 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 112-123 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T2 | 1371-1382 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-74 | Sentence | denotes | Glycosaminoglycans in the blood of hereditary multiple exostoses patients: |
| TextSentencer_T2 | 75-178 | Sentence | denotes | Half reduction of heparan sulfate to chondroitin sulfate ratio and the possible diagnostic application. |
| TextSentencer_T3 | 179-511 | Sentence | denotes | Hereditary multiple exostoses (HME) is an autosomal dominant skeletal disorder with wide variation in clinical phenotype and is caused by heterogeneous germline mutations in two of the Ext genes, EXT-1 and EXT-2, which encode ubiquitously expressed glycosyltransferases involved in the polymerization of heparan sulfate (HS) chains. |
| TextSentencer_T4 | 512-812 | Sentence | denotes | To examine whether the Ext mutation could affect HS structures and amounts in HME patients being heterozygous for the Ext genes, we collected blood from patients and healthy individuals, separated it into plasma and cellular fractions and then isolated glycosaminoglycans (GAGs) from those fractions. |
| TextSentencer_T5 | 813-1186 | Sentence | denotes | A newly established method consisting of a combination of selective ethanol precipitation of GAGs, digestion of GAGs recovered on the filter-cup by direct addition of heparitinase or chondroitinase reaction solution and subsequent high-performance liquid chromatography of the unsaturated disaccharide products enabled the analysis using the least amount of blood (200 µL). |
| TextSentencer_T6 | 1187-1310 | Sentence | denotes | We found that HS structures of HME patients were almost similar to those of controls in both plasma and cellular fractions. |
| TextSentencer_T7 | 1311-1645 | Sentence | denotes | However, interestingly, although both the amounts of HS and chondroitin sulfate (CS) varied depending on the different individuals, the amounts of HS in both the plasma and cellular fractions of HME patient samples were decreased and the ratios of HS to CS (HS/CS) of HME patient samples were almost half those of healthy individuals. |
| TextSentencer_T8 | 1646-1792 | Sentence | denotes | The results suggest that HME patients' blood exhibited reduced HS amounts and HS/CS ratios, which could be used as a diagnostic biomarker for HME. |
| T1 | 0-74 | Sentence | denotes | Glycosaminoglycans in the blood of hereditary multiple exostoses patients: |
| T2 | 75-178 | Sentence | denotes | Half reduction of heparan sulfate to chondroitin sulfate ratio and the possible diagnostic application. |
| T3 | 179-511 | Sentence | denotes | Hereditary multiple exostoses (HME) is an autosomal dominant skeletal disorder with wide variation in clinical phenotype and is caused by heterogeneous germline mutations in two of the Ext genes, EXT-1 and EXT-2, which encode ubiquitously expressed glycosyltransferases involved in the polymerization of heparan sulfate (HS) chains. |
| T4 | 512-812 | Sentence | denotes | To examine whether the Ext mutation could affect HS structures and amounts in HME patients being heterozygous for the Ext genes, we collected blood from patients and healthy individuals, separated it into plasma and cellular fractions and then isolated glycosaminoglycans (GAGs) from those fractions. |
| T5 | 813-1186 | Sentence | denotes | A newly established method consisting of a combination of selective ethanol precipitation of GAGs, digestion of GAGs recovered on the filter-cup by direct addition of heparitinase or chondroitinase reaction solution and subsequent high-performance liquid chromatography of the unsaturated disaccharide products enabled the analysis using the least amount of blood (200 µL). |
| T6 | 1187-1310 | Sentence | denotes | We found that HS structures of HME patients were almost similar to those of controls in both plasma and cellular fractions. |
| T7 | 1311-1645 | Sentence | denotes | However, interestingly, although both the amounts of HS and chondroitin sulfate (CS) varied depending on the different individuals, the amounts of HS in both the plasma and cellular fractions of HME patient samples were decreased and the ratios of HS to CS (HS/CS) of HME patient samples were almost half those of healthy individuals. |
| T8 | 1646-1792 | Sentence | denotes | The results suggest that HME patients' blood exhibited reduced HS amounts and HS/CS ratios, which could be used as a diagnostic biomarker for HME. |
| T1 | 0-74 | Sentence | denotes | Glycosaminoglycans in the blood of hereditary multiple exostoses patients: |
| T2 | 75-178 | Sentence | denotes | Half reduction of heparan sulfate to chondroitin sulfate ratio and the possible diagnostic application. |
| T3 | 179-511 | Sentence | denotes | Hereditary multiple exostoses (HME) is an autosomal dominant skeletal disorder with wide variation in clinical phenotype and is caused by heterogeneous germline mutations in two of the Ext genes, EXT-1 and EXT-2, which encode ubiquitously expressed glycosyltransferases involved in the polymerization of heparan sulfate (HS) chains. |
| T4 | 512-812 | Sentence | denotes | To examine whether the Ext mutation could affect HS structures and amounts in HME patients being heterozygous for the Ext genes, we collected blood from patients and healthy individuals, separated it into plasma and cellular fractions and then isolated glycosaminoglycans (GAGs) from those fractions. |
| T5 | 813-1186 | Sentence | denotes | A newly established method consisting of a combination of selective ethanol precipitation of GAGs, digestion of GAGs recovered on the filter-cup by direct addition of heparitinase or chondroitinase reaction solution and subsequent high-performance liquid chromatography of the unsaturated disaccharide products enabled the analysis using the least amount of blood (200 µL). |
| T6 | 1187-1310 | Sentence | denotes | We found that HS structures of HME patients were almost similar to those of controls in both plasma and cellular fractions. |
| T7 | 1311-1645 | Sentence | denotes | However, interestingly, although both the amounts of HS and chondroitin sulfate (CS) varied depending on the different individuals, the amounts of HS in both the plasma and cellular fractions of HME patient samples were decreased and the ratios of HS to CS (HS/CS) of HME patient samples were almost half those of healthy individuals. |
| T8 | 1646-1792 | Sentence | denotes | The results suggest that HME patients' blood exhibited reduced HS amounts and HS/CS ratios, which could be used as a diagnostic biomarker for HME. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 112-123 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T2 | 1371-1382 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 93-108 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | heparan sulfate |
| T2 | 112-123 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T3 | 483-498 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | heparan sulfate |
| T4 | 500-502 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
| T5 | 561-563 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
| T6 | 1201-1203 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
| T7 | 1364-1366 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
| T8 | 1371-1382 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T9 | 1458-1460 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
| T10 | 1559-1561 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
| T11 | 1569-1571 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
| T12 | 1709-1711 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
| T13 | 1724-1726 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 26-31 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T2 | 26-31 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T3 | 654-659 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T4 | 654-659 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T5 | 1171-1176 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T6 | 1171-1176 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T7 | 1685-1690 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T8 | 1685-1690 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 364-367 | gene:2131 | denotes | Ext |
| T1 | 179-208 | disease:C0015306 | denotes | Hereditary multiple exostoses |
| T2 | 364-367 | gene:2131 | denotes | Ext |
| T3 | 210-213 | disease:C0015306 | denotes | HME |
| T4 | 364-367 | gene:2131 | denotes | Ext |
| T5 | 240-257 | disease:C0263661 | denotes | skeletal disorder |
| T6 | 375-380 | gene:2131 | denotes | EXT-1 |
| T7 | 179-208 | disease:C0015306 | denotes | Hereditary multiple exostoses |
| T8 | 375-380 | gene:2131 | denotes | EXT-1 |
| T9 | 210-213 | disease:C0015306 | denotes | HME |
| T10 | 375-380 | gene:2131 | denotes | EXT-1 |
| T11 | 240-257 | disease:C0263661 | denotes | skeletal disorder |
| T12 | 385-390 | gene:2132 | denotes | EXT-2 |
| T13 | 179-208 | disease:C0015306 | denotes | Hereditary multiple exostoses |
| T14 | 385-390 | gene:2133 | denotes | EXT-2 |
| T15 | 179-208 | disease:C0015306 | denotes | Hereditary multiple exostoses |
| T16 | 385-390 | gene:2132 | denotes | EXT-2 |
| T17 | 210-213 | disease:C0015306 | denotes | HME |
| T18 | 385-390 | gene:2133 | denotes | EXT-2 |
| T19 | 210-213 | disease:C0015306 | denotes | HME |
| T20 | 385-390 | gene:2132 | denotes | EXT-2 |
| T21 | 240-257 | disease:C0263661 | denotes | skeletal disorder |
| T22 | 385-390 | gene:2133 | denotes | EXT-2 |
| T23 | 240-257 | disease:C0263661 | denotes | skeletal disorder |
| R1 | T0 | T1 | associated_with | Ext,Hereditary multiple exostoses |
| R2 | T2 | T3 | associated_with | Ext,HME |
| R3 | T4 | T5 | associated_with | Ext,skeletal disorder |
| R4 | T6 | T7 | associated_with | EXT-1,Hereditary multiple exostoses |
| R5 | T8 | T9 | associated_with | EXT-1,HME |
| R6 | T10 | T11 | associated_with | EXT-1,skeletal disorder |
| R7 | T12 | T13 | associated_with | EXT-2,Hereditary multiple exostoses |
| R8 | T14 | T15 | associated_with | EXT-2,Hereditary multiple exostoses |
| R9 | T16 | T17 | associated_with | EXT-2,HME |
| R10 | T18 | T19 | associated_with | EXT-2,HME |
| R11 | T20 | T21 | associated_with | EXT-2,skeletal disorder |
| R12 | T22 | T23 | associated_with | EXT-2,skeletal disorder |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 0-18 | FMAID:167395 | denotes | Glycosaminoglycans |
| _T2 | 0-18 | FMAID:63011 | denotes | Glycosaminoglycans |
| _T3 | 26-31 | FMAID:256053 | denotes | blood |
| _T4 | 93-100 | FMAID:165191 | denotes | heparan |
| _T5 | 93-100 | FMAID:67110 | denotes | heparan |
| _T6 | 93-108 | FMAID:167405 | denotes | heparan sulfate |
| _T7 | 93-108 | FMAID:63023 | denotes | heparan sulfate |
| _T8 | 112-131 | FMAID:196838 | denotes | chondroitin sulfate |
| _T9 | 112-131 | FMAID:82837 | denotes | chondroitin sulfate |
| _T10 | 221-230 | FMAID:74406 | denotes | autosomal |
| _T11 | 221-230 | FMAID:176862 | denotes | autosomal |
| _T12 | 368-373 | FMAID:198663 | denotes | genes |
| _T13 | 483-490 | FMAID:67110 | denotes | heparan |
| _T14 | 483-490 | FMAID:165191 | denotes | heparan |
| _T15 | 483-498 | FMAID:63023 | denotes | heparan sulfate |
| _T16 | 483-498 | FMAID:167405 | denotes | heparan sulfate |
| _T17 | 634-639 | FMAID:198663 | denotes | genes |
| _T18 | 654-659 | FMAID:256053 | denotes | blood |
| _T19 | 717-723 | FMAID:162307 | denotes | plasma |
| _T20 | 765-783 | FMAID:167395 | denotes | glycosaminoglycans |
| _T21 | 765-783 | FMAID:63011 | denotes | glycosaminoglycans |
| _T22 | 785-789 | FMAID:167404 | denotes | GAGs |
| _T23 | 906-910 | FMAID:167404 | denotes | GAGs |
| _T24 | 925-929 | FMAID:167404 | denotes | GAGs |
| _T25 | 1061-1067 | FMAID:85815 | denotes | liquid |
| _T26 | 1102-1114 | FMAID:196733 | denotes | disaccharide |
| _T27 | 1102-1114 | FMAID:82744 | denotes | disaccharide |
| _T28 | 1171-1176 | FMAID:256053 | denotes | blood |
| _T29 | 1280-1286 | FMAID:162307 | denotes | plasma |
| _T30 | 1371-1390 | FMAID:82837 | denotes | chondroitin sulfate |
| _T31 | 1371-1390 | FMAID:196838 | denotes | chondroitin sulfate |
| _T32 | 1473-1479 | FMAID:162307 | denotes | plasma |
| _T33 | 1685-1690 | FMAID:256053 | denotes | blood |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 210-213 | http://www.uniprot.org/uniprot/P39900 | denotes | HME |
| T2 | 590-593 | http://www.uniprot.org/uniprot/P39900 | denotes | HME |
| T3 | 1218-1221 | http://www.uniprot.org/uniprot/P39900 | denotes | HME |
| T4 | 1506-1509 | http://www.uniprot.org/uniprot/P39900 | denotes | HME |
| T5 | 1579-1582 | http://www.uniprot.org/uniprot/P39900 | denotes | HME |
| T6 | 1671-1674 | http://www.uniprot.org/uniprot/P39900 | denotes | HME |
| T7 | 1788-1791 | http://www.uniprot.org/uniprot/P39900 | denotes | HME |
| T8 | 996-1010 | http://www.uniprot.org/uniprot/P34059 | denotes | chondroitinase |
| T9 | 1392-1394 | http://www.uniprot.org/uniprot/O75390 | denotes | CS |
| T10 | 1565-1567 | http://www.uniprot.org/uniprot/O75390 | denotes | CS |
| T11 | 1572-1574 | http://www.uniprot.org/uniprot/O75390 | denotes | CS |
| T12 | 1727-1729 | http://www.uniprot.org/uniprot/O75390 | denotes | CS |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 996-1010 | http://www.uniprot.org/uniprot/Q571E4 | denotes | chondroitinase |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 221-230 | http://purl.bioontology.org/ontology/NCBITAXON/150701 | denotes | autosomal |
| T2 | 317-330 | http://purl.bioontology.org/ontology/NCBITAXON/1113441 | denotes | heterogeneous |
| T3 | 317-330 | http://purl.bioontology.org/ontology/NCBITAXON/691256 | denotes | heterogeneous |
| T4 | 609-621 | http://purl.bioontology.org/ontology/NCBITAXON/1369269 | denotes | heterozygous |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 101-108 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulfate |
| T2 | 124-131 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulfate |
| T3 | 491-498 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulfate |
| T4 | 1383-1390 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulfate |
| T5 | 728-736 | http://purl.obolibrary.org/obo/GO_0007349 | denotes | cellular |
| T6 | 1291-1299 | http://purl.obolibrary.org/obo/GO_0007349 | denotes | cellular |
| T7 | 1484-1492 | http://purl.obolibrary.org/obo/GO_0007349 | denotes | cellular |
| T8 | 912-921 | http://purl.obolibrary.org/obo/GO_0007586 | denotes | digestion |
| T9 | 996-1010 | http://purl.obolibrary.org/obo/GO_0043890 | denotes | chondroitinase |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 221-230 | http://purl.obolibrary.org/obo/GO_0030849 | denotes | autosomal |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 26-31 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T2 | 654-659 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T3 | 1171-1176 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T4 | 1685-1690 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 290-299 | http://edamontology.org/topic_0625 | denotes | phenotype |
| T2 | 340-349 | http://edamontology.org/topic_0199 | denotes | mutations |
| T3 | 539-547 | http://edamontology.org/topic_0199 | denotes | mutation |
| T4 | 1518-1525 | http://edamontology.org/topic_3277 | denotes | samples |
| T5 | 1591-1598 | http://edamontology.org/topic_3277 | denotes | samples |
| T6 | 1774-1783 | http://edamontology.org/topic_3360 | denotes | biomarker |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 290-299 | http://edamontology.org/data_3275 | denotes | phenotype |
| T2 | 564-574 | http://edamontology.org/data_0883 | denotes | structures |
| T3 | 947-953 | http://edamontology.org/operation_3695 | denotes | filter |
| T4 | 1136-1144 | http://edamontology.org/operation_2945 | denotes | analysis |
| T5 | 1204-1214 | http://edamontology.org/data_0883 | denotes | structures |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_23514715_1_0 | 179-208 | expanded | denotes | Hereditary multiple exostoses |
| SS2_23514715_1_0 | 210-213 | abbr | denotes | HME |
| SS1_23514715_1_1 | 483-498 | expanded | denotes | heparan sulfate |
| SS2_23514715_1_1 | 500-502 | abbr | denotes | HS |
| SS1_23514715_2_0 | 765-783 | expanded | denotes | glycosaminoglycans |
| SS2_23514715_2_0 | 785-789 | abbr | denotes | GAGs |
| SS1_23514715_5_0 | 1371-1390 | expanded | denotes | chondroitin sulfate |
| SS2_23514715_5_0 | 1392-1394 | abbr | denotes | CS |
| SS1_23514715_5_1 | 1559-1567 | expanded | denotes | HS to CS |
| SS2_23514715_5_1 | 1569-1574 | abbr | denotes | HS/CS |
| AE1_23514715_1_0 | SS1_23514715_1_0 | SS2_23514715_1_0 | abbreviatedTo | Hereditary multiple exostoses,HME |
| AE1_23514715_1_1 | SS1_23514715_1_1 | SS2_23514715_1_1 | abbreviatedTo | heparan sulfate,HS |
| AE1_23514715_2_0 | SS1_23514715_2_0 | SS2_23514715_2_0 | abbreviatedTo | glycosaminoglycans,GAGs |
| AE1_23514715_5_0 | SS1_23514715_5_0 | SS2_23514715_5_0 | abbreviatedTo | chondroitin sulfate,CS |
| AE1_23514715_5_1 | SS1_23514715_5_1 | SS2_23514715_5_1 | abbreviatedTo | HS to CS,HS/CS |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 190-208 | HP_0002762 | denotes | multiple exostoses |
| T2 | 199-208 | HP_0100777 | denotes | exostoses |
| T3 | 221-239 | HP_0000006 | denotes | autosomal dominant |
| T4 | 240-257 | HP_0000924 | denotes | skeletal disorder |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 23514715-1#206#211#gene2132 | 385-390 | gene2132 | denotes | EXT-2 |
| 23514715-1#206#211#gene2133 | 385-390 | gene2133 | denotes | EXT-2 |
| 23514715-1#206#211#gene2132 | 385-390 | gene2132 | denotes | EXT-2 |
| 23514715-1#206#211#gene2133 | 385-390 | gene2133 | denotes | EXT-2 |
| 23514715-1#206#211#gene2132 | 385-390 | gene2132 | denotes | EXT-2 |
| 23514715-1#206#211#gene2133 | 385-390 | gene2133 | denotes | EXT-2 |
| 23514715-1#185#188#gene2131 | 364-367 | gene2131 | denotes | Ext |
| 23514715-1#196#201#gene2131 | 375-380 | gene2131 | denotes | EXT-1 |
| 23514715-1#0#29#diseaseC0015306 | 179-208 | diseaseC0015306 | denotes | Hereditary multiple exostoses |
| 23514715-1#31#34#diseaseC0015306 | 210-213 | diseaseC0015306 | denotes | HME |
| 23514715-1#61#78#diseaseC0263661 | 240-257 | diseaseC0263661 | denotes | skeletal disorder |
| 23514715-1#0#29#diseaseC0015306 | 179-208 | diseaseC0015306 | denotes | Hereditary multiple exostoses |
| 23514715-1#31#34#diseaseC0015306 | 210-213 | diseaseC0015306 | denotes | HME |
| 23514715-1#61#78#diseaseC0263661 | 240-257 | diseaseC0263661 | denotes | skeletal disorder |
| 23514715-1#0#29#diseaseC0015306 | 179-208 | diseaseC0015306 | denotes | Hereditary multiple exostoses |
| 23514715-1#31#34#diseaseC0015306 | 210-213 | diseaseC0015306 | denotes | HME |
| 23514715-1#61#78#diseaseC0263661 | 240-257 | diseaseC0263661 | denotes | skeletal disorder |
| 206#211#gene21320#29#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213231#34#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213261#78#diseaseC0263661 | 23514715-1#206#211#gene2132 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21320#29#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213231#34#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213261#78#diseaseC0263661 | 23514715-1#206#211#gene2132 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21320#29#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213231#34#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213261#78#diseaseC0263661 | 23514715-1#206#211#gene2132 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21330#29#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213331#34#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213361#78#diseaseC0263661 | 23514715-1#206#211#gene2133 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21330#29#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213331#34#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213361#78#diseaseC0263661 | 23514715-1#206#211#gene2133 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21330#29#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213331#34#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213361#78#diseaseC0263661 | 23514715-1#206#211#gene2133 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21320#29#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213231#34#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213261#78#diseaseC0263661 | 23514715-1#206#211#gene2132 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21320#29#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213231#34#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213261#78#diseaseC0263661 | 23514715-1#206#211#gene2132 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21320#29#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213231#34#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213261#78#diseaseC0263661 | 23514715-1#206#211#gene2132 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21330#29#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213331#34#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213361#78#diseaseC0263661 | 23514715-1#206#211#gene2133 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21330#29#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213331#34#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213361#78#diseaseC0263661 | 23514715-1#206#211#gene2133 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21330#29#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213331#34#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213361#78#diseaseC0263661 | 23514715-1#206#211#gene2133 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21320#29#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213231#34#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213261#78#diseaseC0263661 | 23514715-1#206#211#gene2132 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21320#29#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213231#34#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213261#78#diseaseC0263661 | 23514715-1#206#211#gene2132 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21320#29#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213231#34#diseaseC0015306 | 23514715-1#206#211#gene2132 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213261#78#diseaseC0263661 | 23514715-1#206#211#gene2132 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21330#29#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213331#34#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213361#78#diseaseC0263661 | 23514715-1#206#211#gene2133 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21330#29#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213331#34#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213361#78#diseaseC0263661 | 23514715-1#206#211#gene2133 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 206#211#gene21330#29#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-2,Hereditary multiple exostoses |
| 206#211#gene213331#34#diseaseC0015306 | 23514715-1#206#211#gene2133 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-2,HME |
| 206#211#gene213361#78#diseaseC0263661 | 23514715-1#206#211#gene2133 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-2,skeletal disorder |
| 185#188#gene21310#29#diseaseC0015306 | 23514715-1#185#188#gene2131 | 23514715-1#0#29#diseaseC0015306 | associated_with | Ext,Hereditary multiple exostoses |
| 185#188#gene213131#34#diseaseC0015306 | 23514715-1#185#188#gene2131 | 23514715-1#31#34#diseaseC0015306 | associated_with | Ext,HME |
| 185#188#gene213161#78#diseaseC0263661 | 23514715-1#185#188#gene2131 | 23514715-1#61#78#diseaseC0263661 | associated_with | Ext,skeletal disorder |
| 185#188#gene21310#29#diseaseC0015306 | 23514715-1#185#188#gene2131 | 23514715-1#0#29#diseaseC0015306 | associated_with | Ext,Hereditary multiple exostoses |
| 185#188#gene213131#34#diseaseC0015306 | 23514715-1#185#188#gene2131 | 23514715-1#31#34#diseaseC0015306 | associated_with | Ext,HME |
| 185#188#gene213161#78#diseaseC0263661 | 23514715-1#185#188#gene2131 | 23514715-1#61#78#diseaseC0263661 | associated_with | Ext,skeletal disorder |
| 185#188#gene21310#29#diseaseC0015306 | 23514715-1#185#188#gene2131 | 23514715-1#0#29#diseaseC0015306 | associated_with | Ext,Hereditary multiple exostoses |
| 185#188#gene213131#34#diseaseC0015306 | 23514715-1#185#188#gene2131 | 23514715-1#31#34#diseaseC0015306 | associated_with | Ext,HME |
| 185#188#gene213161#78#diseaseC0263661 | 23514715-1#185#188#gene2131 | 23514715-1#61#78#diseaseC0263661 | associated_with | Ext,skeletal disorder |
| 196#201#gene21310#29#diseaseC0015306 | 23514715-1#196#201#gene2131 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-1,Hereditary multiple exostoses |
| 196#201#gene213131#34#diseaseC0015306 | 23514715-1#196#201#gene2131 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-1,HME |
| 196#201#gene213161#78#diseaseC0263661 | 23514715-1#196#201#gene2131 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-1,skeletal disorder |
| 196#201#gene21310#29#diseaseC0015306 | 23514715-1#196#201#gene2131 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-1,Hereditary multiple exostoses |
| 196#201#gene213131#34#diseaseC0015306 | 23514715-1#196#201#gene2131 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-1,HME |
| 196#201#gene213161#78#diseaseC0263661 | 23514715-1#196#201#gene2131 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-1,skeletal disorder |
| 196#201#gene21310#29#diseaseC0015306 | 23514715-1#196#201#gene2131 | 23514715-1#0#29#diseaseC0015306 | associated_with | EXT-1,Hereditary multiple exostoses |
| 196#201#gene213131#34#diseaseC0015306 | 23514715-1#196#201#gene2131 | 23514715-1#31#34#diseaseC0015306 | associated_with | EXT-1,HME |
| 196#201#gene213161#78#diseaseC0263661 | 23514715-1#196#201#gene2131 | 23514715-1#61#78#diseaseC0263661 | associated_with | EXT-1,skeletal disorder |
GlycoBiology-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 26-31 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T2 | 26-31 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T3 | 654-659 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T4 | 654-659 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T5 | 1171-1176 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T6 | 1171-1176 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T7 | 1685-1690 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T8 | 1685-1690 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
GlycoBiology-Motifs
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 112-123 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin |
| T2 | 1371-1382 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin |
| T3 | 112-131 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin sulfate |
| T4 | 1371-1390 | http://rdf.glycoinfo.org/glycan/G00018MO | denotes | chondroitin sulfate |
GlycoBiology-Epitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoEpitope-B_T1 | 112-123 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| PD-GlycoEpitope-B_T2 | 1371-1382 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| PD-GlycoEpitope-B_T3 | 93-108 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | heparan sulfate |
| PD-GlycoEpitope-B_T4 | 483-498 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | heparan sulfate |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 26-31 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T2 | 654-659 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T3 | 1171-1176 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T4 | 1685-1690 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 112-123 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T2 | 1371-1382 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T3 | 93-108 | Glycan | denotes | heparan sulfate | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T5 | 483-498 | Glycan | denotes | heparan sulfate | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T6 | 500-502 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T7 | 561-563 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T8 | 1201-1203 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T9 | 1364-1366 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T11 | 1458-1460 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T12 | 1559-1561 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T13 | 1569-1571 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T14 | 1709-1711 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T15 | 1724-1726 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 26-31 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 654-659 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T5 | 1171-1176 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T7 | 1685-1690 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 46-64 | Phenotype | denotes | multiple exostoses | HP:0002762 |
| T2 | 190-208 | Phenotype | denotes | multiple exostoses | HP:0002762 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 35-64 | Disease | denotes | hereditary multiple exostoses | http://purl.obolibrary.org/obo/MONDO_0005508 |
| T2 | 190-208 | Disease | denotes | multiple exostoses | http://purl.obolibrary.org/obo/MONDO_0005508 |
| T3 | 210-213 | Disease | denotes | HME | http://purl.obolibrary.org/obo/MONDO_0000225|http://purl.obolibrary.org/obo/MONDO_0005508 |
| T5 | 590-593 | Disease | denotes | HME | http://purl.obolibrary.org/obo/MONDO_0000225|http://purl.obolibrary.org/obo/MONDO_0005508 |
| T7 | 1218-1221 | Disease | denotes | HME | http://purl.obolibrary.org/obo/MONDO_0000225|http://purl.obolibrary.org/obo/MONDO_0005508 |
| T9 | 1506-1509 | Disease | denotes | HME | http://purl.obolibrary.org/obo/MONDO_0000225|http://purl.obolibrary.org/obo/MONDO_0005508 |
| T11 | 1579-1582 | Disease | denotes | HME | http://purl.obolibrary.org/obo/MONDO_0000225|http://purl.obolibrary.org/obo/MONDO_0005508 |
| T13 | 1671-1674 | Disease | denotes | HME | http://purl.obolibrary.org/obo/MONDO_0000225|http://purl.obolibrary.org/obo/MONDO_0005508 |
| T15 | 1788-1791 | Disease | denotes | HME | http://purl.obolibrary.org/obo/MONDO_0000225|http://purl.obolibrary.org/obo/MONDO_0005508 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 112-123 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T2 | 1371-1382 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T7 | 93-108 | Glycan | denotes | heparan sulfate | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T3 | 483-498 | Glycan | denotes | heparan sulfate | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T4 | 500-502 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T5 | 561-563 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T6 | 1201-1203 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T9 | 1364-1366 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T11 | 1458-1460 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T12 | 1559-1561 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T13 | 1569-1571 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T14 | 1709-1711 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
| T15 | 1724-1726 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 93-108 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
| T2 | 112-123 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T3 | 483-498 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
| T4 | 500-502 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T5 | 561-563 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T6 | 1201-1203 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T7 | 1364-1366 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T8 | 1371-1382 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T9 | 1458-1460 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T10 | 1559-1561 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T11 | 1569-1571 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T12 | 1709-1711 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T13 | 1724-1726 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 46-64 | Phenotype | denotes | multiple exostoses | HP:0002762 |
| T2 | 190-208 | Phenotype | denotes | multiple exostoses | HP:0002762 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 26-31 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 654-659 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T3 | 717-723 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T4 | 1171-1176 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T5 | 1280-1286 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T6 | 1473-1479 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T7 | 1685-1690 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 35-64 | Disease | denotes | hereditary multiple exostoses | MONDO:0005508 |
| T2 | 190-208 | Disease | denotes | multiple exostoses | MONDO:0005508 |
| T3 | 210-213 | Disease | denotes | HME | MONDO:0005508 |
| T4 | 590-593 | Disease | denotes | HME | MONDO:0005508 |
| T5 | 1218-1221 | Disease | denotes | HME | MONDO:0005508 |
| T6 | 1506-1509 | Disease | denotes | HME | MONDO:0005508 |
| T7 | 1579-1582 | Disease | denotes | HME | MONDO:0005508 |
| T8 | 1671-1674 | Disease | denotes | HME | MONDO:0005508 |
| T9 | 1788-1791 | Disease | denotes | HME | MONDO:0005508 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 65-73 | Organism | denotes | patients | 9606 |
| T2 | 594-602 | Organism | denotes | patients | 9606 |
| T3 | 665-673 | Organism | denotes | patients | 9606 |
| T4 | 1222-1230 | Organism | denotes | patients | 9606 |
| T5 | 1510-1517 | Organism | denotes | patient | 9606 |
| T6 | 1583-1590 | Organism | denotes | patient | 9606 |
| T7 | 1675-1683 | Organism | denotes | patients | 9606 |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 93-108 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
| T2 | 112-123 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T3 | 483-498 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
| T4 | 500-502 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T5 | 561-563 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T6 | 1201-1203 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T7 | 1364-1366 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T8 | 1371-1382 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T9 | 1458-1460 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T10 | 1559-1561 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T11 | 1569-1571 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T12 | 1709-1711 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
| T13 | 1724-1726 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-74 | Sentence | denotes | Glycosaminoglycans in the blood of hereditary multiple exostoses patients: |
| T2 | 75-178 | Sentence | denotes | Half reduction of heparan sulfate to chondroitin sulfate ratio and the possible diagnostic application. |
| T3 | 179-511 | Sentence | denotes | Hereditary multiple exostoses (HME) is an autosomal dominant skeletal disorder with wide variation in clinical phenotype and is caused by heterogeneous germline mutations in two of the Ext genes, EXT-1 and EXT-2, which encode ubiquitously expressed glycosyltransferases involved in the polymerization of heparan sulfate (HS) chains. |
| T4 | 512-812 | Sentence | denotes | To examine whether the Ext mutation could affect HS structures and amounts in HME patients being heterozygous for the Ext genes, we collected blood from patients and healthy individuals, separated it into plasma and cellular fractions and then isolated glycosaminoglycans (GAGs) from those fractions. |
| T5 | 813-1186 | Sentence | denotes | A newly established method consisting of a combination of selective ethanol precipitation of GAGs, digestion of GAGs recovered on the filter-cup by direct addition of heparitinase or chondroitinase reaction solution and subsequent high-performance liquid chromatography of the unsaturated disaccharide products enabled the analysis using the least amount of blood (200 µL). |
| T6 | 1187-1310 | Sentence | denotes | We found that HS structures of HME patients were almost similar to those of controls in both plasma and cellular fractions. |
| T7 | 1311-1645 | Sentence | denotes | However, interestingly, although both the amounts of HS and chondroitin sulfate (CS) varied depending on the different individuals, the amounts of HS in both the plasma and cellular fractions of HME patient samples were decreased and the ratios of HS to CS (HS/CS) of HME patient samples were almost half those of healthy individuals. |
| T8 | 1646-1792 | Sentence | denotes | The results suggest that HME patients' blood exhibited reduced HS amounts and HS/CS ratios, which could be used as a diagnostic biomarker for HME. |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 26-31 | Body_part | denotes | blood | FMA:9670 |
| T2 | 221-230 | Body_part | denotes | autosomal | FMA:74406 |
| T3 | 654-659 | Body_part | denotes | blood | FMA:9670 |
| T4 | 717-723 | Body_part | denotes | plasma | FMA:62970 |
| T5 | 1171-1176 | Body_part | denotes | blood | FMA:9670 |
| T6 | 1280-1286 | Body_part | denotes | plasma | FMA:62970 |
| T7 | 1473-1479 | Body_part | denotes | plasma | FMA:62970 |
| T8 | 1685-1690 | Body_part | denotes | blood | FMA:9670 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 26-31 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000315 |
| T2 | 654-659 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 1171-1176 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000315 |
| T4 | 1685-1690 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000315 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 1510-1517 | OrganismTaxon | denotes | patient | 9606 |
| T2 | 1583-1590 | OrganismTaxon | denotes | patient | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 26-31 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 654-659 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T3 | 717-723 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T4 | 1171-1176 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T5 | 1280-1286 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T6 | 1473-1479 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
| T7 | 1685-1690 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |