| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-129 |
Sentence |
denotes |
Increased paediatric hospitalizations for empyema in Australia after introduction of the 7-valent pneumococcal conjugate vaccine. |
| T2 |
130-140 |
Sentence |
denotes |
OBJECTIVE: |
| T3 |
141-319 |
Sentence |
denotes |
To examine rates of paediatric hospitalization for empyema and pneumonia in Australia before and after the introduction of the seven-valent pneumococcal conjugate vaccine (PCV7). |
| T4 |
320-328 |
Sentence |
denotes |
METHODS: |
| T5 |
329-558 |
Sentence |
denotes |
Rates of paediatric hospitalization for empyema and pneumonia (bacterial, viral and all types) were calculated following the codes of the International Classification of Diseases, tenth revision (ICD-10) as a principal diagnosis. |
| T6 |
559-735 |
Sentence |
denotes |
The expected number of hospitalizations after the PCV7 was introduced was estimated on the basis of the observed number of hospitalizations before the introduction of the PCV7. |
| T7 |
736-819 |
Sentence |
denotes |
Incidence rate differences (IRDs) and incidence rate ratios (IRRs) were calculated. |
| T8 |
820-948 |
Sentence |
denotes |
Hospitalization incidence in each study period was expressed as the number of hospitalizations per million (10(6)) person-years. |
| T9 |
949-1162 |
Sentence |
denotes |
The population of children aged 0-19 years in Australia from 1998 to 2004 and from 2005 to 2010, as reported by the Australian Bureau of Statistics, was used to calculate the number of person-years in each period. |
| T10 |
1163-1172 |
Sentence |
denotes |
FINDINGS: |
| T11 |
1173-1327 |
Sentence |
denotes |
In the 5 years following the introduction of the PCV7, hospitalizations for pneumonia were fewer than expected (15 304 fewer; 95% confidence interval, CI: |
| T12 |
1328-1426 |
Sentence |
denotes |
14 646-15 960; IRD: -552 per 10(6) person-years; 95% CI: -576 to -529 per 10(6) person-years; IRR: |
| T13 |
1427-1440 |
Sentence |
denotes |
0.78; 95% CI: |
| T14 |
1441-1452 |
Sentence |
denotes |
0.77-0.78). |
| T15 |
1453-1543 |
Sentence |
denotes |
Hospitalizations for empyema, on the other hand, were more than expected (83 more; 95% CI: |
| T16 |
1544-1556 |
Sentence |
denotes |
37-128; IRD: |
| T17 |
1557-1590 |
Sentence |
denotes |
3 per 10(6) person-years; 95% CI: |
| T18 |
1591-1623 |
Sentence |
denotes |
1-5 per 10(6) person-years; IRR: |
| T19 |
1624-1637 |
Sentence |
denotes |
1.35; 95% CI: |
| T20 |
1638-1649 |
Sentence |
denotes |
1.14-1.59). |
| T21 |
1650-1748 |
Sentence |
denotes |
Reductions in hospitalizations were observed for all ICD-10 pneumonia codes across all age groups. |
| T22 |
1749-1844 |
Sentence |
denotes |
The increase in empyema hospitalizations was only significant among children aged 1 to 4 years. |
| T23 |
1845-1856 |
Sentence |
denotes |
CONCLUSION: |
| T24 |
1857-2039 |
Sentence |
denotes |
The introduction of the PCV7 in Australia was associated with a substantial decrease in hospitalizations for childhood pneumonia and a small increase in hospitalizations for empyema. |
| T1 |
0-129 |
Sentence |
denotes |
Increased paediatric hospitalizations for empyema in Australia after introduction of the 7-valent pneumococcal conjugate vaccine. |
| T2 |
130-140 |
Sentence |
denotes |
OBJECTIVE: |
| T3 |
141-319 |
Sentence |
denotes |
To examine rates of paediatric hospitalization for empyema and pneumonia in Australia before and after the introduction of the seven-valent pneumococcal conjugate vaccine (PCV7). |
| T4 |
320-328 |
Sentence |
denotes |
METHODS: |
| T5 |
329-558 |
Sentence |
denotes |
Rates of paediatric hospitalization for empyema and pneumonia (bacterial, viral and all types) were calculated following the codes of the International Classification of Diseases, tenth revision (ICD-10) as a principal diagnosis. |
| T6 |
559-735 |
Sentence |
denotes |
The expected number of hospitalizations after the PCV7 was introduced was estimated on the basis of the observed number of hospitalizations before the introduction of the PCV7. |
| T7 |
736-819 |
Sentence |
denotes |
Incidence rate differences (IRDs) and incidence rate ratios (IRRs) were calculated. |
| T8 |
820-948 |
Sentence |
denotes |
Hospitalization incidence in each study period was expressed as the number of hospitalizations per million (10(6)) person-years. |
| T9 |
949-1162 |
Sentence |
denotes |
The population of children aged 0-19 years in Australia from 1998 to 2004 and from 2005 to 2010, as reported by the Australian Bureau of Statistics, was used to calculate the number of person-years in each period. |
| T10 |
1163-1172 |
Sentence |
denotes |
FINDINGS: |
| T11 |
1173-1327 |
Sentence |
denotes |
In the 5 years following the introduction of the PCV7, hospitalizations for pneumonia were fewer than expected (15 304 fewer; 95% confidence interval, CI: |
| T12 |
1328-1426 |
Sentence |
denotes |
14 646-15 960; IRD: -552 per 10(6) person-years; 95% CI: -576 to -529 per 10(6) person-years; IRR: |
| T13 |
1427-1440 |
Sentence |
denotes |
0.78; 95% CI: |
| T14 |
1441-1452 |
Sentence |
denotes |
0.77-0.78). |
| T15 |
1453-1543 |
Sentence |
denotes |
Hospitalizations for empyema, on the other hand, were more than expected (83 more; 95% CI: |
| T16 |
1544-1556 |
Sentence |
denotes |
37-128; IRD: |
| T17 |
1557-1590 |
Sentence |
denotes |
3 per 10(6) person-years; 95% CI: |
| T18 |
1591-1623 |
Sentence |
denotes |
1-5 per 10(6) person-years; IRR: |
| T19 |
1624-1637 |
Sentence |
denotes |
1.35; 95% CI: |
| T20 |
1638-1649 |
Sentence |
denotes |
1.14-1.59). |
| T21 |
1650-1748 |
Sentence |
denotes |
Reductions in hospitalizations were observed for all ICD-10 pneumonia codes across all age groups. |
| T22 |
1749-1844 |
Sentence |
denotes |
The increase in empyema hospitalizations was only significant among children aged 1 to 4 years. |
| T23 |
1845-1856 |
Sentence |
denotes |
CONCLUSION: |
| T24 |
1857-2039 |
Sentence |
denotes |
The introduction of the PCV7 in Australia was associated with a substantial decrease in hospitalizations for childhood pneumonia and a small increase in hospitalizations for empyema. |