PubMed:2346948
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 55-66 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T2 | 184-195 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 55-66 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T2 | 184-195 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 55-66 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T2 | 184-195 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 277-281 | HP_0100699 | denotes | scar |
| T2 | 311-315 | HP_0000365 | denotes | DEAE |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-145 | Sentence | denotes | Isolation and some structure analyses of a copolymeric chondroitin sulfate-dermatan sulfate proteoglycan from post-burn, human hypertrophic scar. |
| TextSentencer_T2 | 146-430 | Sentence | denotes | A D-glucuronic acid rich, copolymeric chondroitin sulfate (CS)-dermatan sulfate (DS) proteoglycan (PG) from post-burn hypertrophic scar tissue (HSc) was obtained by DEAE-cellulose chromatography and differential ethanol fractionation, and further purified on a Sepharose CL-6B column. |
| TextSentencer_T3 | 431-470 | Sentence | denotes | CS-DS-PG protein content was 14% (w/w). |
| TextSentencer_T4 | 471-594 | Sentence | denotes | The amino-terminal amino acid sequence of the first ten residues was as follows: NH2-Asp-Glu-Ala-B-Gly-Ile-Gly-Pro-Glu-Val. |
| TextSentencer_T5 | 595-714 | Sentence | denotes | This sequence is identical to that of human embryonic fibroblast cell (IMR-90) CS-DS-PG, as well as to human HSc-DS-PG. |
| TextSentencer_T6 | 715-883 | Sentence | denotes | After chondroitinase ABC treatment, two peptides (Mr 22,000 and 16,000 daltons) were detected by sodium dodecyl sulfate-(polyacryl)amide gel electrophoresis (SDS-PAGE). |
| TextSentencer_T7 | 884-1105 | Sentence | denotes | ELISA analysis using rabbit antiserum raised against a synthetic peptide that contained 15 amino acids in the same sequence as the amino terminus of human fetal membrane PG showed significant reactivity with HSc CS-DS-PG. |
| TextSentencer_T8 | 1106-1232 | Sentence | denotes | HSc CS-DS-PG had an apparent Mr of approximately 78,000 daltons, as determined by Sepharose CL-6B chromatography and SDS-PAGE. |
| TextSentencer_T9 | 1233-1354 | Sentence | denotes | Alkaline borohydride treatment of CS-DS-PG liberated CS-DS glycosaminoglycan (GAG) chains having an Mr of 29,000 daltons. |
| TextSentencer_T10 | 1355-1496 | Sentence | denotes | The conversion of xylose to xylitol indicated that the GAG chains are attached to the PG protein core at O-3 through a xylosyl-seryl linkage. |
| TextSentencer_T11 | 1497-1601 | Sentence | denotes | CS-DS-PG also contained both N and O-linked oligosaccharides and did not aggregate with hyaluronic acid. |
| TextSentencer_T12 | 1602-1784 | Sentence | denotes | These results, together with those reported previously, showed that HSc CS-DS-PG and DS-PG have the same A1-A15 amino acid sequence at the amino terminus but different protein cores. |
| TextSentencer_T13 | 1785-1900 | Sentence | denotes | HSc CS-DS-PG was completely digested with chondroitinase AC and is, therefore, distinctly different from HSc DS-PG. |
| T1 | 0-145 | Sentence | denotes | Isolation and some structure analyses of a copolymeric chondroitin sulfate-dermatan sulfate proteoglycan from post-burn, human hypertrophic scar. |
| T2 | 146-430 | Sentence | denotes | A D-glucuronic acid rich, copolymeric chondroitin sulfate (CS)-dermatan sulfate (DS) proteoglycan (PG) from post-burn hypertrophic scar tissue (HSc) was obtained by DEAE-cellulose chromatography and differential ethanol fractionation, and further purified on a Sepharose CL-6B column. |
| T3 | 431-470 | Sentence | denotes | CS-DS-PG protein content was 14% (w/w). |
| T4 | 471-594 | Sentence | denotes | The amino-terminal amino acid sequence of the first ten residues was as follows: NH2-Asp-Glu-Ala-B-Gly-Ile-Gly-Pro-Glu-Val. |
| T5 | 595-714 | Sentence | denotes | This sequence is identical to that of human embryonic fibroblast cell (IMR-90) CS-DS-PG, as well as to human HSc-DS-PG. |
| T6 | 715-883 | Sentence | denotes | After chondroitinase ABC treatment, two peptides (Mr 22,000 and 16,000 daltons) were detected by sodium dodecyl sulfate-(polyacryl)amide gel electrophoresis (SDS-PAGE). |
| T7 | 884-1105 | Sentence | denotes | ELISA analysis using rabbit antiserum raised against a synthetic peptide that contained 15 amino acids in the same sequence as the amino terminus of human fetal membrane PG showed significant reactivity with HSc CS-DS-PG. |
| T8 | 1106-1232 | Sentence | denotes | HSc CS-DS-PG had an apparent Mr of approximately 78,000 daltons, as determined by Sepharose CL-6B chromatography and SDS-PAGE. |
| T9 | 1233-1354 | Sentence | denotes | Alkaline borohydride treatment of CS-DS-PG liberated CS-DS glycosaminoglycan (GAG) chains having an Mr of 29,000 daltons. |
| T10 | 1355-1496 | Sentence | denotes | The conversion of xylose to xylitol indicated that the GAG chains are attached to the PG protein core at O-3 through a xylosyl-seryl linkage. |
| T11 | 1497-1601 | Sentence | denotes | CS-DS-PG also contained both N and O-linked oligosaccharides and did not aggregate with hyaluronic acid. |
| T12 | 1602-1784 | Sentence | denotes | These results, together with those reported previously, showed that HSc CS-DS-PG and DS-PG have the same A1-A15 amino acid sequence at the amino terminus but different protein cores. |
| T13 | 1785-1900 | Sentence | denotes | HSc CS-DS-PG was completely digested with chondroitinase AC and is, therefore, distinctly different from HSc DS-PG. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 55-66 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T2 | 184-195 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 75-104 | Disease | denotes | dermatan sulfate proteoglycan | http://purl.obolibrary.org/obo/MONDO_0007526|http://purl.obolibrary.org/obo/MONDO_0020682 |
| T3 | 115-119 | Disease | denotes | burn | http://purl.obolibrary.org/obo/MONDO_0043519 |
| T4 | 140-144 | Disease | denotes | scar | http://purl.obolibrary.org/obo/MONDO_0005594 |
| T5 | 259-263 | Disease | denotes | burn | http://purl.obolibrary.org/obo/MONDO_0043519 |
| T6 | 277-281 | Disease | denotes | scar | http://purl.obolibrary.org/obo/MONDO_0005594 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 55-66 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T2 | 184-195 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 55-66 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T2 | 184-195 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 277-288 | Phenotype | denotes | scar tissue | HP:0100699 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 639-659 | Cell | denotes | embryonic fibroblast | http://purl.obolibrary.org/obo/CL:2000042 |
| T2 | 649-659 | Cell | denotes | fibroblast | http://purl.obolibrary.org/obo/CL:0000057 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 282-288 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T2 | 639-659 | Body_part | denotes | embryonic fibroblast | http://purl.obolibrary.org/obo/CL_2000042 |
| T3 | 1039-1053 | Body_part | denotes | fetal membrane | http://purl.obolibrary.org/obo/UBERON_0005630 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 75-104 | Disease | denotes | dermatan sulfate proteoglycan | MONDO:0007526|MONDO:0020682 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 121-126 | Organism | denotes | human | 9606 |
| T2 | 633-638 | Organism | denotes | human | 9606 |
| T3 | 698-703 | Organism | denotes | human | 9606 |
| T4 | 1033-1038 | Organism | denotes | human | 9606 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-145 | Sentence | denotes | Isolation and some structure analyses of a copolymeric chondroitin sulfate-dermatan sulfate proteoglycan from post-burn, human hypertrophic scar. |
| T2 | 146-430 | Sentence | denotes | A D-glucuronic acid rich, copolymeric chondroitin sulfate (CS)-dermatan sulfate (DS) proteoglycan (PG) from post-burn hypertrophic scar tissue (HSc) was obtained by DEAE-cellulose chromatography and differential ethanol fractionation, and further purified on a Sepharose CL-6B column. |
| T3 | 431-470 | Sentence | denotes | CS-DS-PG protein content was 14% (w/w). |
| T4 | 471-714 | Sentence | denotes | The amino-terminal amino acid sequence of the first ten residues was as follows: NH2-Asp-Glu-Ala-B-Gly-Ile-Gly-Pro-Glu-Val. This sequence is identical to that of human embryonic fibroblast cell (IMR-90) CS-DS-PG, as well as to human HSc-DS-PG. |
| T5 | 715-883 | Sentence | denotes | After chondroitinase ABC treatment, two peptides (Mr 22,000 and 16,000 daltons) were detected by sodium dodecyl sulfate-(polyacryl)amide gel electrophoresis (SDS-PAGE). |
| T6 | 884-1105 | Sentence | denotes | ELISA analysis using rabbit antiserum raised against a synthetic peptide that contained 15 amino acids in the same sequence as the amino terminus of human fetal membrane PG showed significant reactivity with HSc CS-DS-PG. |
| T7 | 1106-1232 | Sentence | denotes | HSc CS-DS-PG had an apparent Mr of approximately 78,000 daltons, as determined by Sepharose CL-6B chromatography and SDS-PAGE. |
| T8 | 1233-1354 | Sentence | denotes | Alkaline borohydride treatment of CS-DS-PG liberated CS-DS glycosaminoglycan (GAG) chains having an Mr of 29,000 daltons. |
| T9 | 1355-1496 | Sentence | denotes | The conversion of xylose to xylitol indicated that the GAG chains are attached to the PG protein core at O-3 through a xylosyl-seryl linkage. |
| T10 | 1497-1601 | Sentence | denotes | CS-DS-PG also contained both N and O-linked oligosaccharides and did not aggregate with hyaluronic acid. |
| T11 | 1602-1784 | Sentence | denotes | These results, together with those reported previously, showed that HSc CS-DS-PG and DS-PG have the same A1-A15 amino acid sequence at the amino terminus but different protein cores. |
| T12 | 1785-1900 | Sentence | denotes | HSc CS-DS-PG was completely digested with chondroitinase AC and is, therefore, distinctly different from HSc DS-PG. |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 55-66 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T2 | 184-195 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 282-288 | Body_part | denotes | tissue | FMA:9637 |
| T2 | 649-659 | Body_part | denotes | fibroblast | FMA:63877 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 121-126 | OrganismTaxon | denotes | human | 9606 |
| T2 | 633-638 | OrganismTaxon | denotes | human | 9606 |
| T3 | 698-703 | OrganismTaxon | denotes | human | 9606 |
| T4 | 1033-1038 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 282-288 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T2 | 639-659 | Body_part | denotes | embryonic fibroblast | http://purl.obolibrary.org/obo/CL_2000042 |
| T3 | 1039-1053 | Body_part | denotes | fetal membrane | http://purl.obolibrary.org/obo/UBERON_0005630 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 277-288 | Phenotype | denotes | scar tissue | HP:0100699 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 639-659 | Cell | denotes | embryonic fibroblast | http://purl.obolibrary.org/obo/CL:2000042 |
| T2 | 649-659 | Cell | denotes | fibroblast | http://purl.obolibrary.org/obo/CL:0000057 |