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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-122 Sentence denotes Visceral fat resection in humans: effect on insulin sensitivity, beta-cell function, adipokines, and inflammatory markers.
T2 123-133 Sentence denotes OBJECTIVE:
T3 134-314 Sentence denotes The visceral fat is linked to insulin resistance, the metabolic syndrome, type 2 diabetes and an increased cardiovascular risk, but it is not clear whether it has a causative role.
T4 315-334 Sentence denotes DESIGN AND METHODS:
T5 335-414 Sentence denotes Surgical resection of this fat depot is a research model to address this issue.
T6 415-590 Sentence denotes Twenty premenopausal women with metabolic syndrome and grade III obesity were randomized to undergo Roux-en-Y gastric bypass (RYGBP) either alone or combined with omentectomy.
T7 591-1044 Sentence denotes Insulin sensitivity (IS; euglycemic-hyperinsulinemic clamp), acute insulin response to glucose (AIR; intravenous glucose tolerance test), disposition index (DI = AIR × IS measured by clamp), lipid profile, adipokine profile (leptin, adiponectin, resistin, visfatin, interleukin-6, TNF-α, MCP-1), ultra-sensitive C-reactive protein (CRP), body composition, and abdominal fat echography were assessed prior to surgery and 1, 6, and 12 months post-surgery.
T8 1045-1053 Sentence denotes RESULTS:
T9 1054-1125 Sentence denotes Omentectomy was associated with greater weight loss at all time points.
T10 1126-1163 Sentence denotes IS improved similarly in both groups.
T11 1164-1288 Sentence denotes Omentectomy was associated to lower CRP after 12 months, but it did not influence adipokines and other metabolic parameters.
T12 1289-1487 Sentence denotes Among non-diabetic subjects, omentectomy was associated with a preservation of baseline AIR after 12 months (as opposed to deterioration in the control group) and a greater DI after 6 and 12 months.
T13 1488-1499 Sentence denotes CONCLUSION:
T14 1500-1693 Sentence denotes Although omentectomy did not enhance the effect of RYGBP on insulin sensitivity and adipokines, it was associated with a preservation of insulin secretion, a greater weight loss, and lower CRP.
T1 0-122 Sentence denotes Visceral fat resection in humans: effect on insulin sensitivity, beta-cell function, adipokines, and inflammatory markers.
T2 123-133 Sentence denotes OBJECTIVE:
T3 134-314 Sentence denotes The visceral fat is linked to insulin resistance, the metabolic syndrome, type 2 diabetes and an increased cardiovascular risk, but it is not clear whether it has a causative role.
T4 315-334 Sentence denotes DESIGN AND METHODS:
T5 335-414 Sentence denotes Surgical resection of this fat depot is a research model to address this issue.
T6 415-590 Sentence denotes Twenty premenopausal women with metabolic syndrome and grade III obesity were randomized to undergo Roux-en-Y gastric bypass (RYGBP) either alone or combined with omentectomy.
T7 591-1044 Sentence denotes Insulin sensitivity (IS; euglycemic-hyperinsulinemic clamp), acute insulin response to glucose (AIR; intravenous glucose tolerance test), disposition index (DI = AIR × IS measured by clamp), lipid profile, adipokine profile (leptin, adiponectin, resistin, visfatin, interleukin-6, TNF-α, MCP-1), ultra-sensitive C-reactive protein (CRP), body composition, and abdominal fat echography were assessed prior to surgery and 1, 6, and 12 months post-surgery.
T8 1045-1053 Sentence denotes RESULTS:
T9 1054-1125 Sentence denotes Omentectomy was associated with greater weight loss at all time points.
T10 1126-1163 Sentence denotes IS improved similarly in both groups.
T11 1164-1288 Sentence denotes Omentectomy was associated to lower CRP after 12 months, but it did not influence adipokines and other metabolic parameters.
T12 1289-1487 Sentence denotes Among non-diabetic subjects, omentectomy was associated with a preservation of baseline AIR after 12 months (as opposed to deterioration in the control group) and a greater DI after 6 and 12 months.
T13 1488-1499 Sentence denotes CONCLUSION:
T14 1500-1693 Sentence denotes Although omentectomy did not enhance the effect of RYGBP on insulin sensitivity and adipokines, it was associated with a preservation of insulin secretion, a greater weight loss, and lower CRP.

Allie

Id Subject Object Predicate Lexical cue
SS1_23404948_5_0 515-539 expanded denotes Roux-en-Y gastric bypass
SS2_23404948_5_0 541-546 abbr denotes RYGBP
SS1_23404948_6_0 903-921 expanded denotes C-reactive protein
SS2_23404948_6_0 923-926 abbr denotes CRP
SS1_23404948_6_1 591-610 expanded denotes Insulin sensitivity
SS2_23404948_6_1 612-614 abbr denotes IS
SS1_23404948_6_2 652-685 expanded denotes acute insulin response to glucose
SS2_23404948_6_2 687-690 abbr denotes AIR
AE1_23404948_5_0 SS1_23404948_5_0 SS2_23404948_5_0 abbreviatedTo Roux-en-Y gastric bypass,RYGBP
AE1_23404948_6_0 SS1_23404948_6_0 SS2_23404948_6_0 abbreviatedTo C-reactive protein,CRP
AE1_23404948_6_1 SS1_23404948_6_1 SS2_23404948_6_1 abbreviatedTo Insulin sensitivity,IS
AE1_23404948_6_2 SS1_23404948_6_2 SS2_23404948_6_2 abbreviatedTo acute insulin response to glucose,AIR

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 164-182 HP_0000855 denotes insulin resistance

maxiaofeng52_800_3

Id Subject Object Predicate Lexical cue
T1 188-206 DP denotes metabolic syndrome
T2 447-465 DP denotes metabolic syndrome

wangzhuo19_800_3

Id Subject Object Predicate Lexical cue
T1 447-465 DP denotes metabolic syndrome
T2 188-206 DP denotes metabolic syndrome