PubMed:23242548
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 0-7 | Glycan_Motif | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00052MO |
| T2 | 185-199 | Glycan_Motif | denotes | sialyl-Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
| T3 | 192-199 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T5 | 348-355 | Glycan_Motif | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00052MO |
| T6 | 535-542 | Glycan_Motif | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00052MO |
| T7 | 618-625 | Glycan_Motif | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00052MO |
| T8 | 743-750 | Glycan_Motif | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00052MO |
| T9 | 848-855 | Glycan_Motif | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00052MO |
| T10 | 973-980 | Glycan_Motif | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00052MO |
| T11 | 1090-1104 | Glycan_Motif | denotes | sialyl-Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO |
| T12 | 1097-1104 | Glycan_Motif | denotes | Lewis x | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO |
| T14 | 1199-1206 | Glycan_Motif | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00052MO |
| T15 | 1303-1310 | Glycan_Motif | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00052MO |
| T16 | 1385-1392 | Glycan_Motif | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00052MO |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 291-302 | http://purl.obolibrary.org/obo/MAT_0000038 | denotes | oral cavity |
| T2 | 707-712 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T3 | 707-712 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-200 | Sentence | denotes | Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x. |
| TextSentencer_T2 | 201-316 | Sentence | denotes | Expression and implication of carbohydrate antigens in squamous cell carcinomas (SCCs) in oral cavity was examined. |
| TextSentencer_T3 | 317-389 | Sentence | denotes | In the cell lines, type 2H and Lewis y antigens were markedly expressed. |
| TextSentencer_T4 | 390-534 | Sentence | denotes | In the tissues from SCC patients and benign disorders, type 2H was highly expressed in hyperplasia (96.4 %), displasia (92.9 %) and SCC (100 %). |
| TextSentencer_T5 | 535-657 | Sentence | denotes | Lewis y was, in turn, expressed mainly in cancer tissues (91.3 %), suggesting that Lewis y is a cancer-associated antigen. |
| TextSentencer_T6 | 658-728 | Sentence | denotes | Normal oral mucosa showed no expression of these blood group antigens. |
| TextSentencer_T7 | 729-828 | Sentence | denotes | Surprisingly, Lewis y antigen disappeared in the invasion sites where Ki-67 was definitely stained. |
| TextSentencer_T8 | 829-1035 | Sentence | denotes | Over-expression of Lewis y with manipulation of a fucosyltransferase cDNA resulted in suppression of cell growth and invasion, and knockdown of Lewis y also brought about increased cell growth and invasion. |
| TextSentencer_T9 | 1036-1120 | Sentence | denotes | In either situations, no changes in the expression of sialyl-Lewis x could be found. |
| TextSentencer_T10 | 1121-1241 | Sentence | denotes | Lowered tumor growth and invasion into surrounding tissues were also shown in Lewis y-positive SCC grafts in nu/nu mice. |
| TextSentencer_T11 | 1242-1439 | Sentence | denotes | All these results together with alternative staining between Lewis y and Ki-67 in cancer tissues and FUT1 transfectants suggested that loss of Lewis y is a crucial event for the late stage of SCCs. |
| T1 | 0-200 | Sentence | denotes | Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x. |
| T2 | 201-316 | Sentence | denotes | Expression and implication of carbohydrate antigens in squamous cell carcinomas (SCCs) in oral cavity was examined. |
| T3 | 317-389 | Sentence | denotes | In the cell lines, type 2H and Lewis y antigens were markedly expressed. |
| T4 | 390-534 | Sentence | denotes | In the tissues from SCC patients and benign disorders, type 2H was highly expressed in hyperplasia (96.4 %), displasia (92.9 %) and SCC (100 %). |
| T5 | 535-657 | Sentence | denotes | Lewis y was, in turn, expressed mainly in cancer tissues (91.3 %), suggesting that Lewis y is a cancer-associated antigen. |
| T6 | 658-728 | Sentence | denotes | Normal oral mucosa showed no expression of these blood group antigens. |
| T7 | 729-828 | Sentence | denotes | Surprisingly, Lewis y antigen disappeared in the invasion sites where Ki-67 was definitely stained. |
| T8 | 829-1035 | Sentence | denotes | Over-expression of Lewis y with manipulation of a fucosyltransferase cDNA resulted in suppression of cell growth and invasion, and knockdown of Lewis y also brought about increased cell growth and invasion. |
| T9 | 1036-1120 | Sentence | denotes | In either situations, no changes in the expression of sialyl-Lewis x could be found. |
| T10 | 1121-1241 | Sentence | denotes | Lowered tumor growth and invasion into surrounding tissues were also shown in Lewis y-positive SCC grafts in nu/nu mice. |
| T11 | 1242-1439 | Sentence | denotes | All these results together with alternative staining between Lewis y and Ki-67 in cancer tissues and FUT1 transfectants suggested that loss of Lewis y is a crucial event for the late stage of SCCs. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-7 | https://glytoucan.org/Structures/Glycans/G00052MO | denotes | Lewis y |
| T2 | 185-199 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl-Lewis x |
| T3 | 192-199 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T4 | 192-199 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T5 | 348-355 | https://glytoucan.org/Structures/Glycans/G00052MO | denotes | Lewis y |
| T6 | 535-542 | https://glytoucan.org/Structures/Glycans/G00052MO | denotes | Lewis y |
| T7 | 618-625 | https://glytoucan.org/Structures/Glycans/G00052MO | denotes | Lewis y |
| T8 | 743-750 | https://glytoucan.org/Structures/Glycans/G00052MO | denotes | Lewis y |
| T9 | 848-855 | https://glytoucan.org/Structures/Glycans/G00052MO | denotes | Lewis y |
| T10 | 973-980 | https://glytoucan.org/Structures/Glycans/G00052MO | denotes | Lewis y |
| T11 | 1090-1104 | https://glytoucan.org/Structures/Glycans/G00054MO | denotes | sialyl-Lewis x |
| T12 | 1097-1104 | https://glytoucan.org/Structures/Glycans/G00051MO | denotes | Lewis x |
| T13 | 1097-1104 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Lewis x |
| T14 | 1199-1206 | https://glytoucan.org/Structures/Glycans/G00052MO | denotes | Lewis y |
| T15 | 1303-1310 | https://glytoucan.org/Structures/Glycans/G00052MO | denotes | Lewis y |
| T16 | 1385-1392 | https://glytoucan.org/Structures/Glycans/G00052MO | denotes | Lewis y |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-7 | http://www.glycoepitope.jp/epitopes/EP0018 | denotes | Lewis y |
| T2 | 185-199 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl-Lewis x |
| T3 | 192-199 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T4 | 348-355 | http://www.glycoepitope.jp/epitopes/EP0018 | denotes | Lewis y |
| T5 | 535-542 | http://www.glycoepitope.jp/epitopes/EP0018 | denotes | Lewis y |
| T6 | 618-625 | http://www.glycoepitope.jp/epitopes/EP0018 | denotes | Lewis y |
| T7 | 743-750 | http://www.glycoepitope.jp/epitopes/EP0018 | denotes | Lewis y |
| T8 | 848-855 | http://www.glycoepitope.jp/epitopes/EP0018 | denotes | Lewis y |
| T9 | 973-980 | http://www.glycoepitope.jp/epitopes/EP0018 | denotes | Lewis y |
| T10 | 1090-1104 | http://www.glycoepitope.jp/epitopes/EP0012 | denotes | sialyl-Lewis x |
| T11 | 1097-1104 | http://www.glycoepitope.jp/epitopes/EP0011 | denotes | Lewis x |
| T12 | 1199-1206 | http://www.glycoepitope.jp/epitopes/EP0018 | denotes | Lewis y |
| T13 | 1303-1310 | http://www.glycoepitope.jp/epitopes/EP0018 | denotes | Lewis y |
| T14 | 1385-1392 | http://www.glycoepitope.jp/epitopes/EP0018 | denotes | Lewis y |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 1343-1347 | gene:2523 | denotes | FUT1 |
| T1 | 1324-1330 | disease:C0006826 | denotes | cancer |
| T2 | 1343-1347 | gene:2523 | denotes | FUT1 |
| T3 | 1324-1330 | disease:C1306459 | denotes | cancer |
| T4 | 1343-1347 | gene:2523 | denotes | FUT1 |
| T5 | 1434-1438 | disease:C0007137 | denotes | SCCs |
| R1 | T0 | T1 | associated_with | FUT1,cancer |
| R2 | T2 | T3 | associated_with | FUT1,cancer |
| R3 | T4 | T5 | associated_with | FUT1,SCCs |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_23242548_1_0 | 256-280 | expanded | denotes | squamous cell carcinomas |
| SS2_23242548_1_0 | 282-286 | abbr | denotes | SCCs |
| AE1_23242548_1_0 | SS1_23242548_1_0 | SS2_23242548_1_0 | abbreviatedTo | squamous cell carcinomas,SCCs |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 256-280 | HP_0002860 | denotes | squamous cell carcinomas |
| T2 | 577-583 | HP_0002664 | denotes | cancer |
| T3 | 631-637 | HP_0002664 | denotes | cancer |
| T4 | 1129-1134 | HP_0002664 | denotes | tumor |
| T5 | 1324-1330 | HP_0002664 | denotes | cancer |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 0-7 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T2 | 185-199 | Glycan | denotes | sialyl-Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T3 | 348-355 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T4 | 535-542 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T5 | 618-625 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T6 | 743-750 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T7 | 848-855 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T8 | 973-980 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T9 | 1090-1104 | Glycan | denotes | sialyl-Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T10 | 1199-1206 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T11 | 1303-1310 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T12 | 1385-1392 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 37-60 | Phenotype | denotes | squamous cell carcinoma | HP:0002860 |
| T2 | 256-280 | Phenotype | denotes | squamous cell carcinomas | HP:0002860 |
| T3 | 282-286 | Phenotype | denotes | SCCs | HP:0002860 |
| T4 | 577-583 | Phenotype | denotes | cancer | HP:0002664 |
| T5 | 631-637 | Phenotype | denotes | cancer | HP:0002664 |
| T6 | 1129-1134 | Phenotype | denotes | tumor | HP:0002664 |
| T7 | 1324-1330 | Phenotype | denotes | cancer | HP:0002664 |
| T8 | 1434-1438 | Phenotype | denotes | SCCs | HP:0002860 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 32-60 | Disease | denotes | oral squamous cell carcinoma | http://purl.obolibrary.org/obo/MONDO_0004958 |
| T2 | 256-280 | Disease | denotes | squamous cell carcinomas | http://purl.obolibrary.org/obo/MONDO_0005096 |
| T3 | 282-286 | Disease | denotes | SCCs | http://purl.obolibrary.org/obo/MONDO_0005096 |
| T4 | 477-488 | Disease | denotes | hyperplasia | http://purl.obolibrary.org/obo/MONDO_0005043 |
| T5 | 577-583 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T6 | 631-637 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T7 | 1129-1134 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
| T8 | 1324-1330 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T9 | 1434-1438 | Disease | denotes | SCCs | http://purl.obolibrary.org/obo/MONDO_0005096 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 0-7 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T2 | 185-199 | Glycan | denotes | sialyl-Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T3 | 348-355 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T4 | 535-542 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T5 | 618-625 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T6 | 743-750 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T7 | 848-855 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T8 | 973-980 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T9 | 1090-1104 | Glycan | denotes | sialyl-Lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO |
| T10 | 1199-1206 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T11 | 1303-1310 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
| T12 | 1385-1392 | Glycan | denotes | Lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 0-7 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T2 | 185-199 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl-Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T3 | 348-355 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T4 | 535-542 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T5 | 618-625 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T6 | 743-750 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T7 | 848-855 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T8 | 973-980 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T9 | 1090-1104 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl-Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T10 | 1199-1206 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T11 | 1303-1310 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T12 | 1385-1392 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 37-60 | Phenotype | denotes | squamous cell carcinoma | HP:0002860 |
| T2 | 256-280 | Phenotype | denotes | squamous cell carcinomas | HP:0002860 |
| T3 | 282-286 | Phenotype | denotes | SCCs | HP:0002860 |
| T4 | 577-583 | Phenotype | denotes | cancer | HP:0002664 |
| T5 | 631-637 | Phenotype | denotes | cancer | HP:0002664 |
| T6 | 1129-1134 | Phenotype | denotes | tumor | HP:0002664 |
| T7 | 1324-1330 | Phenotype | denotes | cancer | HP:0002664 |
| T8 | 1434-1438 | Phenotype | denotes | SCCs | HP:0002860 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 291-302 | Body_part | denotes | oral cavity | http://purl.obolibrary.org/obo/UBERON_0000167 |
| T2 | 665-676 | Body_part | denotes | oral mucosa | http://purl.obolibrary.org/obo/UBERON_0003729 |
| T3 | 707-712 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 32-60 | Disease | denotes | oral squamous cell carcinoma | MONDO:0004958 |
| T2 | 256-280 | Disease | denotes | squamous cell carcinomas | MONDO:0005096 |
| T3 | 282-286 | Disease | denotes | SCCs | MONDO:0005096 |
| T4 | 477-488 | Disease | denotes | hyperplasia | MONDO:0005043 |
| T5 | 577-583 | Disease | denotes | cancer | MONDO:0004992 |
| T6 | 631-637 | Disease | denotes | cancer | MONDO:0004992 |
| T7 | 1129-1134 | Disease | denotes | tumor | MONDO:0005070 |
| T8 | 1324-1330 | Disease | denotes | cancer | MONDO:0004992 |
| T9 | 1434-1438 | Disease | denotes | SCCs | MONDO:0005096 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 414-422 | Organism | denotes | patients | 9606 |
| T2 | 1236-1240 | Organism | denotes | mice | 10088 |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 0-7 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T2 | 185-199 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl-Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T3 | 348-355 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T4 | 535-542 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T5 | 618-625 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T6 | 743-750 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T7 | 848-855 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T8 | 973-980 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T9 | 1090-1104 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | sialyl-Lewis x | http://www.glycoepitope.jp/epitopes/EP0012 |
| T10 | 1199-1206 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T11 | 1303-1310 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
| T12 | 1385-1392 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-200 | Sentence | denotes | Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x. |
| T2 | 201-316 | Sentence | denotes | Expression and implication of carbohydrate antigens in squamous cell carcinomas (SCCs) in oral cavity was examined. |
| T3 | 317-389 | Sentence | denotes | In the cell lines, type 2H and Lewis y antigens were markedly expressed. |
| T4 | 390-534 | Sentence | denotes | In the tissues from SCC patients and benign disorders, type 2H was highly expressed in hyperplasia (96.4 %), displasia (92.9 %) and SCC (100 %). |
| T5 | 535-657 | Sentence | denotes | Lewis y was, in turn, expressed mainly in cancer tissues (91.3 %), suggesting that Lewis y is a cancer-associated antigen. |
| T6 | 658-728 | Sentence | denotes | Normal oral mucosa showed no expression of these blood group antigens. |
| T7 | 729-828 | Sentence | denotes | Surprisingly, Lewis y antigen disappeared in the invasion sites where Ki-67 was definitely stained. |
| T8 | 829-1035 | Sentence | denotes | Over-expression of Lewis y with manipulation of a fucosyltransferase cDNA resulted in suppression of cell growth and invasion, and knockdown of Lewis y also brought about increased cell growth and invasion. |
| T9 | 1036-1120 | Sentence | denotes | In either situations, no changes in the expression of sialyl-Lewis x could be found. |
| T10 | 1121-1241 | Sentence | denotes | Lowered tumor growth and invasion into surrounding tissues were also shown in Lewis y-positive SCC grafts in nu/nu mice. |
| T11 | 1242-1439 | Sentence | denotes | All these results together with alternative staining between Lewis y and Ki-67 in cancer tissues and FUT1 transfectants suggested that loss of Lewis y is a crucial event for the late stage of SCCs. |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 76-83 | Body_part | denotes | tissues | FMA:9637 |
| T2 | 291-302 | Body_part | denotes | oral cavity | FMA:20292 |
| T3 | 397-404 | Body_part | denotes | tissues | FMA:9637 |
| T4 | 584-591 | Body_part | denotes | tissues | FMA:9637 |
| T5 | 665-676 | Body_part | denotes | oral mucosa | FMA:59660 |
| T6 | 707-712 | Body_part | denotes | blood | FMA:9670 |
| T7 | 1172-1179 | Body_part | denotes | tissues | FMA:9637 |
| T8 | 1331-1338 | Body_part | denotes | tissues | FMA:9637 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 291-302 | Body_part | denotes | oral cavity | http://purl.obolibrary.org/obo/MAT_0000038 |
| T2 | 707-712 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000315 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 1236-1240 | OrganismTaxon | denotes | mice | 10088 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 291-302 | Body_part | denotes | oral cavity | http://purl.obolibrary.org/obo/UBERON_0000167 |
| T2 | 665-676 | Body_part | denotes | oral mucosa | http://purl.obolibrary.org/obo/UBERON_0003729 |
| T3 | 707-712 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 291-302 | Body_part | denotes | oral cavity | http://purl.obolibrary.org/obo/MAT_0000038 |
| T2 | 707-712 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |