PubMed:23241745 / 448-618 JSONTXT

{"project":"PubTator4TogoVar","denotations":[{"id":"23241745_0","span":{"begin":141,"end":147},"obj":"ProteinMutation"},{"id":"23241745_1","span":{"begin":151,"end":157},"obj":"ProteinMutation"}],"attributes":[{"id":"23241745_0_ProteinMutation","pred":"proteinmutation","subj":"23241745_0","obj":"rs33939927"},{"id":"23241745_1_ProteinMutation","pred":"proteinmutation","subj":"23241745_1","obj":"rs34637584"}],"text":"We demonstrate that LRRK2 autophosphorylation on Ser(1292) occurs in vivo and is enhanced by several familial PD mutations including N1437H, R1441G/C, G2019S, and I2020T."}

{"project":"c_corpus","denotations":[{"id":"T42","span":{"begin":20,"end":25},"obj":"PR:Q5S006"},{"id":"T43","span":{"begin":20,"end":25},"obj":"PR:000003033"},{"id":"T44","span":{"begin":20,"end":25},"obj":"PR:Q5S007"},{"id":"T45","span":{"begin":46,"end":52},"obj":"CVCL_U693"},{"id":"T50","span":{"begin":49,"end":52},"obj":"Q62230"},{"id":"T51","span":{"begin":49,"end":52},"obj":"PR:000001931"},{"id":"T54","span":{"begin":49,"end":52},"obj":"PR:P18168"},{"id":"T48","span":{"begin":49,"end":52},"obj":"GO:0005790"},{"id":"T46","span":{"begin":49,"end":52},"obj":"CHEBI:32838"},{"id":"T47","span":{"begin":49,"end":52},"obj":"CHEBI:32839"},{"id":"T49","span":{"begin":49,"end":52},"obj":"CHEBI:29999"},{"id":"T53","span":{"begin":49,"end":52},"obj":"CHEBI:17115"},{"id":"T52","span":{"begin":49,"end":52},"obj":"SO:0001444"},{"id":"T55","span":{"begin":146,"end":152},"obj":"CHEBI:86642"}],"text":"We demonstrate that LRRK2 autophosphorylation on Ser(1292) occurs in vivo and is enhanced by several familial PD mutations including N1437H, R1441G/C, G2019S, and I2020T."}

{"project":"UseCases_ArguminSci_Discourse","denotations":[{"id":"T4","span":{"begin":0,"end":170},"obj":"DRI_Outcome"}],"text":"We demonstrate that LRRK2 autophosphorylation on Ser(1292) occurs in vivo and is enhanced by several familial PD mutations including N1437H, R1441G/C, G2019S, and I2020T."}

{"project":"PubMed_ArguminSci","denotations":[{"id":"T3","span":{"begin":0,"end":170},"obj":"DRI_Outcome"}],"text":"We demonstrate that LRRK2 autophosphorylation on Ser(1292) occurs in vivo and is enhanced by several familial PD mutations including N1437H, R1441G/C, G2019S, and I2020T."}