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PubMed:23209647 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-116 Sentence denotes Generating embryonic stem cells from the inbred mouse strain DBA/2J, a model of glaucoma and other complex diseases.
TextSentencer_T2 117-311 Sentence denotes Mouse embryonic stem (ES) cells are derived from the inner cell mass of blastocyst stage embryos and are used primarily for the creation of genetically engineered strains through gene targeting.
TextSentencer_T3 312-486 Sentence denotes While some inbred strains of mice are permissive to the derivation of embryonic stem cell lines and are therefore easily engineered, others are nonpermissive or recalcitrant.
TextSentencer_T4 487-688 Sentence denotes Genetic engineering of recalcitrant strain backgrounds requires gene targeting in a permissive background followed by extensive backcrossing of the engineered allele into the desired strain background.
TextSentencer_T5 689-840 Sentence denotes The inbred mouse strain DBA/2J is a recalcitrant strain that is used as a model of many human diseases, including glaucoma, deafness and schizophrenia.
TextSentencer_T6 841-936 Sentence denotes Here, we describe the generation of germ-line competent ES cell lines derived from DBA/2J mice.
TextSentencer_T7 937-1102 Sentence denotes We also demonstrate the utility of DBA/2J ES cells with the creation of conditional knockout allele for Endothelin-2 (Edn2) directly on the DBA/2J strain background.
T1 0-116 Sentence denotes Generating embryonic stem cells from the inbred mouse strain DBA/2J, a model of glaucoma and other complex diseases.
T2 117-311 Sentence denotes Mouse embryonic stem (ES) cells are derived from the inner cell mass of blastocyst stage embryos and are used primarily for the creation of genetically engineered strains through gene targeting.
T3 312-486 Sentence denotes While some inbred strains of mice are permissive to the derivation of embryonic stem cell lines and are therefore easily engineered, others are nonpermissive or recalcitrant.
T4 487-688 Sentence denotes Genetic engineering of recalcitrant strain backgrounds requires gene targeting in a permissive background followed by extensive backcrossing of the engineered allele into the desired strain background.
T5 689-840 Sentence denotes The inbred mouse strain DBA/2J is a recalcitrant strain that is used as a model of many human diseases, including glaucoma, deafness and schizophrenia.
T6 841-936 Sentence denotes Here, we describe the generation of germ-line competent ES cell lines derived from DBA/2J mice.
T7 937-1102 Sentence denotes We also demonstrate the utility of DBA/2J ES cells with the creation of conditional knockout allele for Endothelin-2 (Edn2) directly on the DBA/2J strain background.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 713-716 gene:6223 denotes DBA
T1 826-839 disease:C0036341 denotes schizophrenia
T2 713-716 gene:8378 denotes DBA
T3 826-839 disease:C0036341 denotes schizophrenia
R1 T0 T1 associated_with DBA,schizophrenia
R2 T2 T3 associated_with DBA,schizophrenia

Allie

Id Subject Object Predicate Lexical cue
SS1_23209647_1_0 123-137 expanded denotes embryonic stem
SS2_23209647_1_0 139-141 abbr denotes ES
SS1_23209647_6_0 1041-1053 expanded denotes Endothelin-2
SS2_23209647_6_0 1055-1059 abbr denotes Edn2
AE1_23209647_1_0 SS1_23209647_1_0 SS2_23209647_1_0 abbreviatedTo embryonic stem,ES
AE1_23209647_6_0 SS1_23209647_6_0 SS2_23209647_6_0 abbreviatedTo Endothelin-2,Edn2

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 803-811 HP_0000501 denotes glaucoma
T2 813-821 HP_0000365 denotes deafness
T3 826-839 HP_0100753 denotes schizophrenia

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
23209647-4#24#27#gene8378 713-716 gene8378 denotes DBA
23209647-4#24#27#gene6223 713-716 gene6223 denotes DBA
23209647-4#137#150#diseaseC0036341 826-839 diseaseC0036341 denotes schizophrenia
24#27#gene8378137#150#diseaseC0036341 23209647-4#24#27#gene8378 23209647-4#137#150#diseaseC0036341 associated_with DBA,schizophrenia
24#27#gene6223137#150#diseaseC0036341 23209647-4#24#27#gene6223 23209647-4#137#150#diseaseC0036341 associated_with DBA,schizophrenia

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T1702 713-716 gene:8378 denotes DBA
T1703 826-839 disease:C0036341 denotes schizophrenia
R1 T1702 T1703 associated_with DBA,schizophrenia
R2 T1702 T1703 associated_with DBA,schizophrenia

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 170-185 http://purl.obolibrary.org/obo/UBERON_0000087 denotes inner cell mass
PD-UBERON-AE-B_T2 189-199 http://purl.obolibrary.org/obo/UBERON_0000358 denotes blastocyst
PD-UBERON-AE-B_T3 206-213 http://purl.obolibrary.org/obo/UBERON_0000922 denotes embryos
PD-UBERON-AE-B_T4 605-614 http://purl.obolibrary.org/obo/UBERON_2000106 denotes extensive

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 206-213 http://purl.obolibrary.org/obo/UBERON_0000922 denotes embryos
PD-UBERON-AE-B_T2 605-614 http://purl.obolibrary.org/obo/UBERON_2000106 denotes extensive
PD-UBERON-AE-B_T3 170-185 http://purl.obolibrary.org/obo/UBERON_0000087 denotes inner cell mass
PD-UBERON-AE-B_T4 189-199 http://purl.obolibrary.org/obo/UBERON_0000358 denotes blastocyst