PubMed:23129521 JSONTXT

{"project":"Allie","denotations":[{"id":"SS1_23129521_2_0","span":{"begin":155,"end":180},"obj":"expanded"},{"id":"SS2_23129521_2_0","span":{"begin":182,"end":188},"obj":"abbr"},{"id":"SS1_23129521_2_1","span":{"begin":208,"end":227},"obj":"expanded"},{"id":"SS2_23129521_2_1","span":{"begin":229,"end":232},"obj":"abbr"}],"relations":[{"id":"AE1_23129521_2_0","pred":"abbreviatedTo","subj":"SS1_23129521_2_0","obj":"SS2_23129521_2_0"},{"id":"AE1_23129521_2_1","pred":"abbreviatedTo","subj":"SS1_23129521_2_1","obj":"SS2_23129521_2_1"}],"text":"Intraoperative high frequency ultrasound in intracerebral high-grade tumors.\nPURPOSE: To demonstrate the utility of a new concept of intraoperative use of high frequency ultrasound (hfioUS) in maximizing the extent of resection (EOR) of intracerebral high-grade tumors.\nMATERIALS AND METHODS: 22 Patients harboring an intracerebral high-grade tumor were retrospectively included in this study (14 primary tumors, 8 metastasis). 14 of them had a perilesional edema equal or greater to lesion volume, 3 had previously received radiotherapy. Following macroscopic tumor debulking, the small (11 × 31 mm) L15 - 7io (Philips, Bothell, USA) high-frequency probe (7 - 15 MHz) was introduced into the resection cavity and its walls were meticulously scanned to search for tumor remnants. Postoperative MR scan was evaluated by a board-certified independent neuroradiologist, who assessed the EOR.\nRESULTS: Gross total resection was achieved in 21 patients (95.5 %). One patient had a small tumor remnant (6 × 4 × 3 mm) of a very large (80 × 60 × 74 mm) anaplastic astrocytoma, detected in the postoperative MR scan. A permanent postoperative hemiparesis was diagnosed in one patient with a metastasis in the motor area, while the other patients recovered without permanent neurological deficits from the surgery.\nCONCLUSION: The hfioUS probe allowed in this study a precise detection of the tumor and a detailed discrimination between normal, pathological and edematous tissue in all 22 cases."}

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":262,"end":268},"obj":"HP_0002664"}],"text":"Intraoperative high frequency ultrasound in intracerebral high-grade tumors.\nPURPOSE: To demonstrate the utility of a new concept of intraoperative use of high frequency ultrasound (hfioUS) in maximizing the extent of resection (EOR) of intracerebral high-grade tumors.\nMATERIALS AND METHODS: 22 Patients harboring an intracerebral high-grade tumor were retrospectively included in this study (14 primary tumors, 8 metastasis). 14 of them had a perilesional edema equal or greater to lesion volume, 3 had previously received radiotherapy. Following macroscopic tumor debulking, the small (11 × 31 mm) L15 - 7io (Philips, Bothell, USA) high-frequency probe (7 - 15 MHz) was introduced into the resection cavity and its walls were meticulously scanned to search for tumor remnants. Postoperative MR scan was evaluated by a board-certified independent neuroradiologist, who assessed the EOR.\nRESULTS: Gross total resection was achieved in 21 patients (95.5 %). One patient had a small tumor remnant (6 × 4 × 3 mm) of a very large (80 × 60 × 74 mm) anaplastic astrocytoma, detected in the postoperative MR scan. A permanent postoperative hemiparesis was diagnosed in one patient with a metastasis in the motor area, while the other patients recovered without permanent neurological deficits from the surgery.\nCONCLUSION: The hfioUS probe allowed in this study a precise detection of the tumor and a detailed discrimination between normal, pathological and edematous tissue in all 22 cases."}