PubMed:2303034
Annnotations
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-115 | Sentence | denotes | hSP, the domain-duplicated homolog of pS2 protein, is co-expressed with pS2 in stomach but not in breast carcinoma. |
| TextSentencer_T2 | 116-432 | Sentence | denotes | Approximately 50% of human breast tumors secrete a small cysteine-rich protein, pS2, of unknown function. pS2 protein was recently found to be homologous to a porcine protein with hormonogastric activity, pancreatic spasmolytic polypeptide (PSP), in which the 5-cysteine domain present in pS2 is tandemly duplicated. |
| TextSentencer_T3 | 433-531 | Sentence | denotes | We have characterized cDNA species encoding PSP and its human and mouse counterparts, hSP and mSP. |
| TextSentencer_T4 | 532-667 | Sentence | denotes | We show that hSP and pS2 are separately encoded in the genome, and that the two proteins are co-expressed in normal stomach epithelium. |
| TextSentencer_T5 | 668-729 | Sentence | denotes | However, expression of hSP was not detected in breast tumors. |
| TextSentencer_T6 | 730-958 | Sentence | denotes | Computer analysis revealed that the pattern of conserved cysteine residues in hSP and pS2, the P domain, is present at the N termini of two other mammalian proteins, intestinal sucrase-isomaltase and lysosomal alpha-glucosidase. |
| T1 | 0-115 | Sentence | denotes | hSP, the domain-duplicated homolog of pS2 protein, is co-expressed with pS2 in stomach but not in breast carcinoma. |
| T2 | 116-432 | Sentence | denotes | Approximately 50% of human breast tumors secrete a small cysteine-rich protein, pS2, of unknown function. pS2 protein was recently found to be homologous to a porcine protein with hormonogastric activity, pancreatic spasmolytic polypeptide (PSP), in which the 5-cysteine domain present in pS2 is tandemly duplicated. |
| T3 | 433-531 | Sentence | denotes | We have characterized cDNA species encoding PSP and its human and mouse counterparts, hSP and mSP. |
| T4 | 532-667 | Sentence | denotes | We show that hSP and pS2 are separately encoded in the genome, and that the two proteins are co-expressed in normal stomach epithelium. |
| T5 | 668-729 | Sentence | denotes | However, expression of hSP was not detected in breast tumors. |
| T6 | 730-958 | Sentence | denotes | Computer analysis revealed that the pattern of conserved cysteine residues in hSP and pS2, the P domain, is present at the N termini of two other mammalian proteins, intestinal sucrase-isomaltase and lysosomal alpha-glucosidase. |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 38-41 | gene:7031 | denotes | pS2 |
| T1 | 98-114 | disease:C0006142 | denotes | breast carcinoma |
| T2 | 38-41 | gene:7031 | denotes | pS2 |
| T3 | 98-114 | disease:C0678222 | denotes | breast carcinoma |
| T4 | 38-41 | gene:338412 | denotes | pS2 |
| T5 | 98-114 | disease:C0006142 | denotes | breast carcinoma |
| T6 | 38-41 | gene:338412 | denotes | pS2 |
| T7 | 98-114 | disease:C0678222 | denotes | breast carcinoma |
| T8 | 38-41 | gene:5664 | denotes | pS2 |
| T9 | 98-114 | disease:C0006142 | denotes | breast carcinoma |
| T10 | 38-41 | gene:5664 | denotes | pS2 |
| T11 | 98-114 | disease:C0678222 | denotes | breast carcinoma |
| R1 | T0 | T1 | associated_with | pS2,breast carcinoma |
| R2 | T2 | T3 | associated_with | pS2,breast carcinoma |
| R3 | T4 | T5 | associated_with | pS2,breast carcinoma |
| R4 | T6 | T7 | associated_with | pS2,breast carcinoma |
| R5 | T8 | T9 | associated_with | pS2,breast carcinoma |
| R6 | T10 | T11 | associated_with | pS2,breast carcinoma |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 143-156 | HP_0003002 | denotes | breast tumors |
| T2 | 143-156 | HP_0100013 | denotes | breast tumors |
| T3 | 150-156 | HP_0002664 | denotes | tumors |
| T4 | 421-431 | HP_0009609 | denotes | duplicated |
| T5 | 715-728 | HP_0003002 | denotes | breast tumors |
| T6 | 715-728 | HP_0100013 | denotes | breast tumors |
| T7 | 722-728 | HP_0002664 | denotes | tumors |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 2303034-1#57#78#gene6678 | 173-194 | gene6678 | denotes | cysteine-rich protein |
| 2303034-1#27#40#diseaseC1458155 | 143-156 | diseaseC1458155 | denotes | breast tumors |
| 57#78#gene667827#40#diseaseC1458155 | 2303034-1#57#78#gene6678 | 2303034-1#27#40#diseaseC1458155 | associated_with | cysteine-rich protein,breast tumors |
DisGeNet-2017-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2737 | 38-41 | gene:5664 | denotes | pS2 |
| T2738 | 98-114 | disease:C0678222 | denotes | breast carcinoma |
| R1 | T2737 | T2738 | associated_with | pS2,breast carcinoma |
| R2 | T2737 | T2738 | associated_with | pS2,breast carcinoma |
| R3 | T2737 | T2738 | associated_with | pS2,breast carcinoma |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 79-86 | http://purl.obolibrary.org/obo/UBERON_0000945 | denotes | stomach |
| PD-UBERON-AE-B_T2 | 648-655 | http://purl.obolibrary.org/obo/UBERON_0000945 | denotes | stomach |
| PD-UBERON-AE-B_T3 | 98-104 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE-B_T4 | 143-149 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE-B_T5 | 715-721 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE-B_T6 | 656-666 | http://purl.obolibrary.org/obo/UBERON_0000483 | denotes | epithelium |
| PD-UBERON-AE-B_T7 | 896-906 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 79-86 | http://purl.obolibrary.org/obo/UBERON_0000945 | denotes | stomach |
| PD-UBERON-AE-B_T2 | 648-655 | http://purl.obolibrary.org/obo/UBERON_0000945 | denotes | stomach |
| PD-UBERON-AE-B_T3 | 656-666 | http://purl.obolibrary.org/obo/UBERON_0000483 | denotes | epithelium |
| PD-UBERON-AE-B_T4 | 98-104 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE-B_T5 | 143-149 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE-B_T6 | 715-721 | http://purl.obolibrary.org/obo/UBERON_0000310 | denotes | breast |
| PD-UBERON-AE-B_T7 | 648-666 | http://purl.obolibrary.org/obo/UBERON_0001276 | denotes | stomach epithelium |
| PD-UBERON-AE-B_T8 | 896-906 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |