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PubMed:23007704 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-115 Sentence denotes Identification of recurrence-related genes by integrating microRNA and gene expression profiling of gastric cancer.
TextSentencer_T2 116-331 Sentence denotes We previously analyzed the microRNA (miRNA) expression pattern in gastric cancer with and without recurrence and obtained 17 differentially expressed miRNAs with potential to predict recurrence risk for GC patients.
TextSentencer_T3 332-498 Sentence denotes In the present study, we aimed to investigate recurrence-related genes which may be regulated by the differentially expressed miRNAs identified in our prior research.
TextSentencer_T4 499-640 Sentence denotes Three different miRNA target gene databases (miRanda, TargetScan and PicTar) were used for searching the potential genes regulated by miRNAs.
TextSentencer_T5 641-745 Sentence denotes A combination was performed between miRNA target genes and recurrence-related gene expression profiling.
TextSentencer_T6 746-851 Sentence denotes Three bioinformatics algorithms (PAM, SVM and RF) were used to feature recurrence-related gene selection.
TextSentencer_T7 852-948 Sentence denotes In addition, we validated the expression levels of the genes in GC patients using real-time PCR.
TextSentencer_T8 949-1022 Sentence denotes A total of 3,263 genes were identified as potential targets of 17 miRNAs.
TextSentencer_T9 1023-1192 Sentence denotes We identified 2,736 differential expressed genes using the SAM method based on 22K oligo microarray data which included 7 recurrence and 4 without recurrence GC samples.
TextSentencer_T10 1193-1380 Sentence denotes Combining the target genes regulated by miRNAs and the differentially expressed genes between recurrence and non-recurrence groups, we identified 228 differential genes for further study.
TextSentencer_T11 1381-1522 Sentence denotes Finally, we identified HNRPA0 and PRDM4 as risk biomarkers of GC patients, which were regulated by hsa-miR‑194 and hsa-miR-373, respectively.
TextSentencer_T12 1523-1725 Sentence denotes Our data indicated that HNRPA0 and PRDM4 may be involved in the recurrence process of GC and have potential to act as new prognostic biomarkers in predicting recurrence risk for gastric cancer patients.
T1 0-115 Sentence denotes Identification of recurrence-related genes by integrating microRNA and gene expression profiling of gastric cancer.
T2 116-331 Sentence denotes We previously analyzed the microRNA (miRNA) expression pattern in gastric cancer with and without recurrence and obtained 17 differentially expressed miRNAs with potential to predict recurrence risk for GC patients.
T3 332-498 Sentence denotes In the present study, we aimed to investigate recurrence-related genes which may be regulated by the differentially expressed miRNAs identified in our prior research.
T4 499-640 Sentence denotes Three different miRNA target gene databases (miRanda, TargetScan and PicTar) were used for searching the potential genes regulated by miRNAs.
T5 641-745 Sentence denotes A combination was performed between miRNA target genes and recurrence-related gene expression profiling.
T6 746-851 Sentence denotes Three bioinformatics algorithms (PAM, SVM and RF) were used to feature recurrence-related gene selection.
T7 852-948 Sentence denotes In addition, we validated the expression levels of the genes in GC patients using real-time PCR.
T8 949-1022 Sentence denotes A total of 3,263 genes were identified as potential targets of 17 miRNAs.
T9 1023-1192 Sentence denotes We identified 2,736 differential expressed genes using the SAM method based on 22K oligo microarray data which included 7 recurrence and 4 without recurrence GC samples.
T10 1193-1380 Sentence denotes Combining the target genes regulated by miRNAs and the differentially expressed genes between recurrence and non-recurrence groups, we identified 228 differential genes for further study.
T11 1381-1522 Sentence denotes Finally, we identified HNRPA0 and PRDM4 as risk biomarkers of GC patients, which were regulated by hsa-miR‑194 and hsa-miR-373, respectively.
T12 1523-1725 Sentence denotes Our data indicated that HNRPA0 and PRDM4 may be involved in the recurrence process of GC and have potential to act as new prognostic biomarkers in predicting recurrence risk for gastric cancer patients.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 779-782 gene:5066 denotes PAM
T1 817-827 disease:C1458156 denotes recurrence
T2 779-782 gene:23077 denotes PAM
T3 817-827 disease:C1458156 denotes recurrence
R1 T0 T1 associated_with PAM,recurrence
R2 T2 T3 associated_with PAM,recurrence

Allie

Id Subject Object Predicate Lexical cue
SS1_23007704_1_0 143-151 expanded denotes microRNA
SS2_23007704_1_0 153-158 abbr denotes miRNA
AE1_23007704_1_0 SS1_23007704_1_0 SS2_23007704_1_0 abbreviatedTo microRNA,miRNA

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 182-196 HP_0012126 denotes gastric cancer
T2 190-196 HP_0002664 denotes cancer
T3 1701-1715 HP_0012126 denotes gastric cancer
T4 1709-1715 HP_0002664 denotes cancer

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
23007704-11#24#30#gene10949 1547-1553 gene10949 denotes HNRPA0
23007704-11#35#40#gene11108 1558-1563 gene11108 denotes PRDM4
23007704-11#178#192#diseaseC0024623 1701-1715 diseaseC0024623 denotes gastric cancer
23007704-11#178#192#diseaseC0699791 1701-1715 diseaseC0699791 denotes gastric cancer
23007704-11#178#192#diseaseC0024623 1701-1715 diseaseC0024623 denotes gastric cancer
23007704-11#178#192#diseaseC0699791 1701-1715 diseaseC0699791 denotes gastric cancer
24#30#gene10949178#192#diseaseC0024623 23007704-11#24#30#gene10949 23007704-11#178#192#diseaseC0024623 associated_with HNRPA0,gastric cancer
24#30#gene10949178#192#diseaseC0699791 23007704-11#24#30#gene10949 23007704-11#178#192#diseaseC0699791 associated_with HNRPA0,gastric cancer
24#30#gene10949178#192#diseaseC0024623 23007704-11#24#30#gene10949 23007704-11#178#192#diseaseC0024623 associated_with HNRPA0,gastric cancer
24#30#gene10949178#192#diseaseC0699791 23007704-11#24#30#gene10949 23007704-11#178#192#diseaseC0699791 associated_with HNRPA0,gastric cancer
35#40#gene11108178#192#diseaseC0024623 23007704-11#35#40#gene11108 23007704-11#178#192#diseaseC0024623 associated_with PRDM4,gastric cancer
35#40#gene11108178#192#diseaseC0699791 23007704-11#35#40#gene11108 23007704-11#178#192#diseaseC0699791 associated_with PRDM4,gastric cancer
35#40#gene11108178#192#diseaseC0024623 23007704-11#35#40#gene11108 23007704-11#178#192#diseaseC0024623 associated_with PRDM4,gastric cancer
35#40#gene11108178#192#diseaseC0699791 23007704-11#35#40#gene11108 23007704-11#178#192#diseaseC0699791 associated_with PRDM4,gastric cancer

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2283 1547-1553 gene:10949 denotes HNRPA0
T2284 1701-1715 disease:C0024623 denotes gastric cancer
T2285 1558-1563 gene:11108 denotes PRDM4
R1 T2283 T2284 associated_with HNRPA0,gastric cancer
R2 T2283 T2284 associated_with HNRPA0,gastric cancer
R3 T2285 T2284 associated_with PRDM4,gastric cancer
R4 T2285 T2284 associated_with PRDM4,gastric cancer