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sonoma2

Id Subject Object Predicate Lexical cue
T0 7-15 REG denotes specific
T1 16-32 POSREG denotes gain-of-function
T2 33-41 MPA denotes activity
T3 45-48 GENE denotes p53
T4 49-56 VAR denotes mutants
T5 60-71 DISEASE denotes lung cancer
T6 79-82 GENE denotes p53
T7 83-92 VAR denotes mutations
T8 122-129 VAR denotes changes
T9 130-139 REG denotes resulting
T10 140-142 REG denotes in
T11 143-153 MPA denotes expression
T12 166-172 VAR denotes mutant
T13 173-180 GENE denotes protein
T14 187-191 POSREG denotes gain
T15 206-209 MPA denotes GOF
T16 211-219 MPA denotes activity
T17 229-237 POSREG denotes dominant
T18 238-252 MPA denotes oncogenic role
T19 272-276 NEGREG denotes loss
T20 280-288 MPA denotes function
T21 292-301 VAR denotes wild-type
T22 302-305 GENE denotes p53
T23 302-305 GENE denotes p53
T24 307-317 VAR denotes Knock-down
T25 321-327 VAR denotes mutant
T26 328-331 GENE denotes p53
T27 341-352 DISEASE denotes lung cancer
T28 390-393 GENE denotes p53
T29 394-401 VAR denotes mutants
T30 402-409 REG denotes results
T31 413-417 NEGREG denotes loss
T32 421-433 MPA denotes GOF activity
T33 437-442 REG denotes shown
T34 446-454 NEGREG denotes lowering
T35 458-474 CPA denotes cell growth rate
T36 480-491 DISEASE denotes lung cancer
T37 504-508 DISEASE denotes ABC1
T38 504-508 GENE denotes ABC1
T39 513-518 DISEASE denotes H1437
T40 520-528 REG denotes carrying
T41 540-547 VAR denotes mutants
T42 548-557 VAR denotes p53-P278S
T43 548-557 GENE denotes p53-P278S
T44 562-568 VAR denotes -R267P
T45 570-574 REG denotes show
T46 575-584 NEGREG denotes reduction
T47 588-599 CPA denotes growth rate
T48 603-613 NEGREG denotes knock-down
T49 617-620 GENE denotes p53
T50 621-627 MPA denotes levels
T51 646-655 NEGREG denotes reduction
T52 663-666 GENE denotes p53
T53 667-672 MPA denotes level
T54 673-680 REG denotes induces
T55 681-685 NEGREG denotes loss
T56 689-703 CPA denotes tumorigenicity
T57 721-725 DISEASE denotes ABC1
T58 721-725 GENE denotes ABC1
T59 736-745 POSREG denotes escalates
T60 746-760 CPA denotes tumorigenicity
T61 765-770 DISEASE denotes H1437
T62 799-814 MPA denotes transactivation
T63 828-831 GENE denotes p53
T64 832-838 REG denotes target
T65 844-853 MPA denotes promoters
T66 908-916 VAR denotes p53-null
T67 908-916 GENE denotes p53-null
T68 917-934 DISEASE denotes H1299 lung cancer
T69 971-977 VAR denotes mutant
T70 978-981 GENE denotes p53
T71 982-988 REG denotes target
T72 998-1001 GENE denotes Axl
T73 1006-1015 POSREG denotes activated
T74 1028-1035 VAR denotes mutants
T75 1041-1044 GENE denotes p21
T76 1045-1053 MPA denotes promoter
T77 1058-1067 POSREG denotes activated
T78 1071-1080 VAR denotes p53-R267P
T79 1071-1080 GENE denotes p53-R267P
T80 1085-1094 VAR denotes wild-type
T81 1095-1098 GENE denotes p53
T82 1103-1106 NEGREG denotes not
T83 1110-1119 VAR denotes p53-P278S
T84 1110-1119 GENE denotes p53-P278S
T85 1121-1128 REG denotes showing
T86 1137-1147 REG denotes difference
T87 1151-1175 MPA denotes transcriptional activity
T88 1192-1199 VAR denotes mutants
T89 1225-1231 VAR denotes allele
T90 1232-1243 REG denotes specificity
T91 1252-1255 MPA denotes GOF
T92 1256-1259 GENE denotes p53
T93 1260-1267 VAR denotes mutants
T94 1297-1308 REG denotes specificity
T95 1312-1321 REG denotes dependent
T96 1329-1353 MPA denotes transactivation property
T97 1357-1360 MPA denotes GOF
T98 1361-1364 GENE denotes p53
T99 1383-1393 REG denotes importance
T100 1397-1400 GENE denotes p21
T101 1401-1411 POSREG denotes activation
T102 1415-1420 CPA denotes tumor
T103 1415-1420 DISEASE denotes tumor
T104 1421-1432 NEGREG denotes suppression
T105 1436-1439 GENE denotes p53
R29 T8 T14 CauseOf changes,gain
R30 T8 T17 CauseOf changes,dominant
R31 T8 T19 CauseOf changes,loss
R32 T9 T10 CauseOf resulting,in
R33 T11 T9 ThemeOf expression,resulting
R34 T11 T10 ThemeOf expression,in
R35 T11 T12 ThemeOf expression,mutant
R36 T12 T9 CauseOf mutant,resulting
R37 T12 T14 CauseOf mutant,gain
R38 T12 T17 CauseOf mutant,dominant
R39 T12 T19 CauseOf mutant,loss
R40 T13 T10 ThemeOf protein,in
R41 T13 T11 ThemeOf protein,expression
R42 T13 T12 ThemeOf protein,mutant
R43 T13 T15 ThemeOf protein,GOF
R44 T13 T16 ThemeOf protein,activity
R45 T13 T18 ThemeOf protein,oncogenic role
R190 T75 T77 ThemeOf p21,activated
R191 T76 T74 ThemeOf promoter,mutants
R192 T76 T77 ThemeOf promoter,activated
R193 T80 T73 CauseOf wild-type,activated
R194 T80 T77 CauseOf wild-type,activated
R0 T0 T1 CauseOf specific,gain-of-function
R1 T2 T1 ThemeOf activity,gain-of-function
R2 T4 T1 CauseOf mutants,gain-of-function
R3 T2 T0 ThemeOf activity,specific
R4 T3 T2 ThemeOf p53,activity
R5 T2 T4 ThemeOf activity,mutants
R6 T3 T0 ThemeOf p53,specific
R7 T3 T1 ThemeOf p53,gain-of-function
R8 T3 T4 ThemeOf p53,mutants
R9 T4 T0 CauseOf mutants,specific
R10 T5 T0 ThemeOf lung cancer,specific
R11 T5 T1 ThemeOf lung cancer,gain-of-function
R12 T5 T2 ThemeOf lung cancer,activity
R13 T5 T4 ThemeOf lung cancer,mutants
R14 T6 T4 ThemeOf p53,mutants
R15 T6 T7 ThemeOf p53,mutations
R16 T6 T8 ThemeOf p53,changes
R17 T6 T11 ThemeOf p53,expression
R18 T7 T1 CauseOf mutations,gain-of-function
R19 T7 T9 CauseOf mutations,resulting
R20 T7 T10 CauseOf mutations,in
R21 T7 T11 CauseOf mutations,expression
R22 T7 T14 CauseOf mutations,gain
R23 T7 T17 CauseOf mutations,dominant
R24 T7 T19 CauseOf mutations,loss
R25 T8 T1 CauseOf changes,gain-of-function
R26 T8 T9 CauseOf changes,resulting
R27 T8 T10 CauseOf changes,in
R28 T8 T11 CauseOf changes,expression
R46 T15 T14 ThemeOf GOF,gain
R47 T16 T14 ThemeOf activity,gain
R48 T15 T11 ThemeOf GOF,expression
R49 T15 T16 ThemeOf GOF,activity
R50 T18 T17 ThemeOf oncogenic role,dominant
R51 T19 T17 CauseOf loss,dominant
R52 T20 T19 ThemeOf function,loss
R53 T20 T21 ThemeOf function,wild-type
R54 T21 T14 CauseOf wild-type,gain
R55 T21 T17 CauseOf wild-type,dominant
R56 T21 T19 CauseOf wild-type,loss
R57 T22 T11 ThemeOf p53,expression
R58 T22 T16 ThemeOf p53,activity
R59 T22 T18 ThemeOf p53,oncogenic role
R60 T22 T19 ThemeOf p53,loss
R61 T22 T20 ThemeOf p53,function
R62 T22 T21 ThemeOf p53,wild-type
R63 T24 T17 CauseOf Knock-down,dominant
R64 T24 T19 CauseOf Knock-down,loss
R65 T27 T24 ThemeOf lung cancer,Knock-down
R66 T24 T30 CauseOf Knock-down,results
R67 T24 T31 CauseOf Knock-down,loss
R68 T24 T33 CauseOf Knock-down,shown
R69 T24 T34 CauseOf Knock-down,lowering
R70 T25 T30 CauseOf mutant,results
R71 T25 T31 CauseOf mutant,loss
R72 T25 T34 CauseOf mutant,lowering
R73 T26 T24 ThemeOf p53,Knock-down
R74 T26 T25 ThemeOf p53,mutant
R75 T26 T29 ThemeOf p53,mutants
R76 T27 T25 ThemeOf lung cancer,mutant
R77 T27 T29 ThemeOf lung cancer,mutants
R78 T27 T30 ThemeOf lung cancer,results
R79 T28 T24 ThemeOf p53,Knock-down
R80 T28 T25 ThemeOf p53,mutant
R81 T28 T29 ThemeOf p53,mutants
R82 T29 T30 CauseOf mutants,results
R83 T29 T31 CauseOf mutants,loss
R84 T29 T33 CauseOf mutants,shown
R85 T29 T34 CauseOf mutants,lowering
R86 T32 T31 ThemeOf GOF activity,loss
R87 T31 T34 CauseOf loss,lowering
R88 T32 T33 ThemeOf GOF activity,shown
R89 T35 T34 ThemeOf cell growth rate,lowering
R90 T35 T33 ThemeOf cell growth rate,shown
R91 T36 T34 ThemeOf lung cancer,lowering
R92 T36 T40 ThemeOf lung cancer,carrying
R93 T36 T41 ThemeOf lung cancer,mutants
R94 T36 T44 ThemeOf lung cancer,-R267P
R95 T36 T45 ThemeOf lung cancer,show
R96 T36 T46 ThemeOf lung cancer,reduction
R97 T37 T40 ThemeOf ABC1,carrying
R98 T37 T41 ThemeOf ABC1,mutants
R99 T37 T44 ThemeOf ABC1,-R267P
R100 T37 T45 ThemeOf ABC1,show
R101 T37 T46 ThemeOf ABC1,reduction
R102 T39 T40 ThemeOf H1437,carrying
R103 T39 T41 ThemeOf H1437,mutants
R104 T39 T42 ThemeOf H1437,p53-P278S
R105 T39 T44 ThemeOf H1437,-R267P
R106 T39 T45 ThemeOf H1437,show
R107 T39 T46 ThemeOf H1437,reduction
R108 T39 T48 ThemeOf H1437,knock-down
R109 T39 T50 ThemeOf H1437,levels
R110 T40 T41 ThemeOf carrying,mutants
R111 T40 T45 CauseOf carrying,show
R112 T40 T46 CauseOf carrying,reduction
R113 T41 T34 CauseOf mutants,lowering
R114 T42 T41 ThemeOf p53-P278S,mutants
R115 T44 T41 ThemeOf -R267P,mutants
R116 T41 T45 CauseOf mutants,show
R117 T41 T46 CauseOf mutants,reduction
R118 T41 T47 CauseOf mutants,growth rate
R119 T41 T55 CauseOf mutants,loss
R120 T41 T59 CauseOf mutants,escalates
R121 T42 T40 ThemeOf p53-P278S,carrying
R122 T42 T46 CauseOf p53-P278S,reduction
R123 T44 T45 CauseOf -R267P,show
R124 T44 T46 CauseOf -R267P,reduction
R125 T47 T46 ThemeOf growth rate,reduction
R126 T48 T46 CauseOf knock-down,reduction
R127 T47 T45 ThemeOf growth rate,show
R128 T48 T47 CauseOf knock-down,growth rate
R129 T48 T34 CauseOf knock-down,lowering
R130 T48 T40 CauseOf knock-down,carrying
R131 T48 T45 CauseOf knock-down,show
R132 T50 T48 ThemeOf levels,knock-down
R133 T48 T54 CauseOf knock-down,induces
R134 T48 T55 CauseOf knock-down,loss
R135 T48 T59 CauseOf knock-down,escalates
R136 T49 T41 ThemeOf p53,mutants
R137 T49 T48 ThemeOf p53,knock-down
R138 T49 T50 ThemeOf p53,levels
R139 T51 T46 CauseOf reduction,reduction
R140 T51 T54 CauseOf reduction,induces
R141 T51 T55 CauseOf reduction,loss
R142 T51 T59 CauseOf reduction,escalates
R143 T52 T51 ThemeOf p53,reduction
R144 T52 T53 ThemeOf p53,level
R145 T53 T51 ThemeOf level,reduction
R146 T53 T54 ThemeOf level,induces
R147 T54 T55 CauseOf induces,loss
R148 T56 T55 ThemeOf tumorigenicity,loss
R149 T56 T54 ThemeOf tumorigenicity,induces
R150 T57 T51 ThemeOf ABC1,reduction
R151 T57 T53 ThemeOf ABC1,level
R152 T57 T54 ThemeOf ABC1,induces
R153 T57 T55 ThemeOf ABC1,loss
R154 T57 T56 ThemeOf ABC1,tumorigenicity
R155 T57 T59 ThemeOf ABC1,escalates
R156 T60 T59 ThemeOf tumorigenicity,escalates
R157 T61 T60 ThemeOf H1437,tumorigenicity
R158 T61 T55 ThemeOf H1437,loss
R159 T61 T59 ThemeOf H1437,escalates
R160 T62 T64 ThemeOf transactivation,target
R161 T62 T65 ThemeOf transactivation,promoters
R162 T63 T62 ThemeOf p53,transactivation
R163 T63 T64 ThemeOf p53,target
R164 T63 T65 ThemeOf p53,promoters
R165 T65 T64 ThemeOf promoters,target
R166 T68 T62 ThemeOf H1299 lung cancer,transactivation
R167 T68 T64 ThemeOf H1299 lung cancer,target
R168 T68 T65 ThemeOf H1299 lung cancer,promoters
R169 T68 T66 ThemeOf H1299 lung cancer,p53-null
R170 T71 T69 ThemeOf target,mutant
R171 T69 T73 CauseOf mutant,activated
R172 T69 T77 CauseOf mutant,activated
R173 T69 T85 CauseOf mutant,showing
R174 T70 T69 ThemeOf p53,mutant
R175 T70 T71 ThemeOf p53,target
R176 T70 T73 ThemeOf p53,activated
R177 T70 T74 ThemeOf p53,mutants
R178 T71 T73 ThemeOf target,activated
R179 T72 T69 ThemeOf Axl,mutant
R180 T72 T71 ThemeOf Axl,target
R181 T72 T73 ThemeOf Axl,activated
R182 T72 T74 ThemeOf Axl,mutants
R183 T74 T73 CauseOf mutants,activated
R184 T74 T77 CauseOf mutants,activated
R185 T74 T82 CauseOf mutants,not
R186 T74 T85 CauseOf mutants,showing
R187 T74 T86 CauseOf mutants,difference
R188 T75 T74 ThemeOf p21,mutants
R189 T75 T76 ThemeOf p21,promoter
R195 T80 T82 CauseOf wild-type,not
R196 T80 T85 CauseOf wild-type,showing
R197 T80 T86 CauseOf wild-type,difference
R198 T81 T74 ThemeOf p53,mutants
R199 T81 T76 ThemeOf p53,promoter
R200 T81 T77 ThemeOf p53,activated
R201 T81 T78 ThemeOf p53,p53-R267P
R202 T81 T80 ThemeOf p53,wild-type
R203 T81 T88 ThemeOf p53,mutants
R204 T82 T85 CauseOf not,showing
R205 T83 T85 CauseOf p53-P278S,showing
R206 T86 T85 ThemeOf difference,showing
R207 T87 T86 ThemeOf transcriptional activity,difference
R208 T88 T86 CauseOf mutants,difference
R209 T87 T85 ThemeOf transcriptional activity,showing
R210 T87 T88 ThemeOf transcriptional activity,mutants
R211 T88 T73 CauseOf mutants,activated
R212 T88 T77 CauseOf mutants,activated
R213 T88 T82 CauseOf mutants,not
R214 T88 T85 CauseOf mutants,showing
R215 T90 T89 ThemeOf specificity,allele
R216 T91 T89 ThemeOf GOF,allele
R217 T89 T101 CauseOf allele,activation
R218 T89 T104 CauseOf allele,suppression
R219 T91 T90 ThemeOf GOF,specificity
R220 T90 T93 ThemeOf specificity,mutants
R221 T91 T93 ThemeOf GOF,mutants
R222 T92 T89 ThemeOf p53,allele
R223 T92 T90 ThemeOf p53,specificity
R224 T92 T91 ThemeOf p53,GOF
R225 T92 T93 ThemeOf p53,mutants
R226 T92 T94 ThemeOf p53,specificity
R227 T93 T95 CauseOf mutants,dependent
R228 T93 T101 CauseOf mutants,activation
R229 T93 T104 CauseOf mutants,suppression
R230 T94 T95 ThemeOf specificity,dependent
R231 T96 T94 ThemeOf transactivation property,specificity
R232 T96 T95 ThemeOf transactivation property,dependent
R233 T97 T95 ThemeOf GOF,dependent
R234 T96 T97 ThemeOf transactivation property,GOF
R235 T98 T96 ThemeOf p53,transactivation property
R236 T96 T99 ThemeOf transactivation property,importance
R237 T97 T104 CauseOf GOF,suppression
R238 T98 T93 ThemeOf p53,mutants
R239 T98 T94 ThemeOf p53,specificity
R240 T98 T95 ThemeOf p53,dependent
R241 T98 T97 ThemeOf p53,GOF
R242 T101 T99 ThemeOf activation,importance
R243 T104 T99 ThemeOf suppression,importance
R244 T100 T99 ThemeOf p21,importance
R245 T100 T101 ThemeOf p21,activation
R246 T100 T104 ThemeOf p21,suppression
R247 T104 T101 ThemeOf suppression,activation
R248 T102 T99 ThemeOf tumor,importance
R249 T102 T101 ThemeOf tumor,activation
R250 T102 T104 ThemeOf tumor,suppression
R251 T105 T99 ThemeOf p53,importance
R252 T105 T104 CauseOf p53,suppression

DisGeNET

Id Subject Object Predicate Lexical cue
T0 45-48 gene:7157 denotes p53
T1 60-71 disease:C0242379 denotes lung cancer
T2 45-48 gene:7157 denotes p53
T3 60-71 disease:C0684249 denotes lung cancer
T4 328-331 gene:7157 denotes p53
T5 341-352 disease:C0684249 denotes lung cancer
T6 328-331 gene:7157 denotes p53
T7 341-352 disease:C0242379 denotes lung cancer
T8 390-393 gene:7157 denotes p53
T9 341-352 disease:C0242379 denotes lung cancer
T10 390-393 gene:7157 denotes p53
T11 341-352 disease:C0684249 denotes lung cancer
R1 T0 T1 associated_with p53,lung cancer
R2 T2 T3 associated_with p53,lung cancer
R3 T4 T5 associated_with p53,lung cancer
R4 T6 T7 associated_with p53,lung cancer
R5 T8 T9 associated_with p53,lung cancer
R6 T10 T11 associated_with p53,lung cancer

Allie

Id Subject Object Predicate Lexical cue
SS1_22989750_1_0 187-203 expanded denotes gain of function
SS2_22989750_1_0 206-209 abbr denotes GOF
AE1_22989750_1_0 SS1_22989750_1_0 SS2_22989750_1_0 abbreviatedTo gain of function,GOF

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 341-352 HP_0100526 denotes lung cancer
T2 346-352 HP_0002664 denotes cancer
T3 480-491 HP_0100526 denotes lung cancer
T4 485-491 HP_0002664 denotes cancer
T5 923-934 HP_0100526 denotes lung cancer
T6 928-934 HP_0002664 denotes cancer
T7 1415-1420 HP_0002664 denotes tumor

kaiyin_test

Id Subject Object Predicate Lexical cue
T3 16-32 PosReg denotes gain-of-function
T4 33-41 MPA denotes activity
T1 45-48 Gene denotes p53
T2 49-56 Var denotes mutants
T36 60-71 Disease denotes lung cancer
T6 79-82 Gene denotes p53
T5 83-92 Var denotes mutations
T7 130-142 Reg denotes resulting in
T8 143-153 MPA denotes expression
T9 187-203 PosReg denotes gain of function
T10 211-219 MPA denotes activity
T13 390-393 Gene denotes p53
T14 394-401 Var denotes mutants
T16 413-417 NegReg denotes loss
T17 425-433 MPA denotes activity
T18 446-454 NegReg denotes lowering
T19 458-474 CPA denotes cell growth rate
T20 540-568 Var denotes mutants p53-P278S and -R267P
T21 575-584 NegReg denotes reduction
T22 588-599 MPA denotes growth rate
T24 646-655 NegReg denotes reduction
T23 663-666 Var denotes p53
T26 681-685 NegReg denotes loss
T27 689-703 MPA denotes tumorigenicity
T28 736-745 PosReg denotes escalates
T29 746-760 MPA denotes tumorigenicity
R1 T1 T2 ThemeOf p53,mutants
R10 T14 T16 CauseOf mutants,loss
R11 T17 T16 ThemeOf activity,loss
R12 T14 T18 CauseOf mutants,lowering
R13 T19 T18 ThemeOf cell growth rate,lowering
R14 T20 T21 CauseOf mutants p53-P278S and -R267P,reduction
R15 T22 T21 ThemeOf growth rate,reduction
R18 T27 T26 ThemeOf tumorigenicity,loss
R19 T24 T23 ThemeOf reduction,p53
R2 T2 T3 CauseOf mutants,gain-of-function
R20 T23 T28 CauseOf p53,escalates
R21 T29 T28 ThemeOf tumorigenicity,escalates
R22 T23 T26 CauseOf p53,loss
R27 T36 T3 ThemeOf lung cancer,gain-of-function
R3 T4 T3 ThemeOf activity,gain-of-function
R4 T5 T7 CauseOf mutations,resulting in
R5 T8 T7 ThemeOf expression,resulting in
R6 T6 T5 ThemeOf p53,mutations
R7 T5 T9 CauseOf mutations,gain of function
R8 T10 T9 ThemeOf activity,gain of function
R9 T13 T14 ThemeOf p53,mutants

name_no

Id Subject Object Predicate Lexical cue
T3 16-32 PosReg denotes gain-of-function
T4 33-41 MPA denotes activity
T1 45-48 Gene denotes p53
T2 49-56 Var denotes mutants
T36 60-71 Disease denotes lung cancer
T6 79-82 Gene denotes p53
T5 83-92 Var denotes mutations
T7 130-142 Reg denotes resulting in
T8 143-153 MPA denotes expression
T9 187-203 PosReg denotes gain of function
T10 211-219 MPA denotes activity
T13 390-393 Gene denotes p53
T14 394-401 Var denotes mutants
T16 413-417 NegReg denotes loss
T17 425-433 MPA denotes activity
T18 446-454 NegReg denotes lowering
T19 458-474 CPA denotes cell growth rate
T20 540-568 Var denotes mutants p53-P278S and -R267P
T21 575-584 NegReg denotes reduction
T22 588-599 MPA denotes growth rate
T24 646-655 NegReg denotes reduction
T23 663-666 Var denotes p53
T26 681-685 NegReg denotes loss
T27 689-703 MPA denotes tumorigenicity
T28 736-745 PosReg denotes escalates
T29 746-760 MPA denotes tumorigenicity
R1 T1 T2 ThemeOf p53,mutants
R10 T14 T16 CauseOf mutants,loss
R11 T17 T16 ThemeOf activity,loss
R12 T14 T18 CauseOf mutants,lowering
R13 T19 T18 ThemeOf cell growth rate,lowering
R14 T20 T21 CauseOf mutants p53-P278S and -R267P,reduction
R15 T22 T21 ThemeOf growth rate,reduction
R18 T27 T26 ThemeOf tumorigenicity,loss
R19 T24 T23 ThemeOf reduction,p53
R2 T2 T3 CauseOf mutants,gain-of-function
R20 T23 T28 CauseOf p53,escalates
R21 T29 T28 ThemeOf tumorigenicity,escalates
R22 T23 T26 CauseOf p53,loss
R27 T36 T3 ThemeOf lung cancer,gain-of-function
R3 T4 T3 ThemeOf activity,gain-of-function
R4 T5 T7 CauseOf mutations,resulting in
R5 T8 T7 ThemeOf expression,resulting in
R6 T6 T5 ThemeOf p53,mutations
R7 T5 T9 CauseOf mutations,gain of function
R8 T10 T9 ThemeOf activity,gain of function
R9 T13 T14 ThemeOf p53,mutants